Drug sensing by the ribosome induces translational arrest via active site perturbation

Molecular Cell

Volumn 56, Issue 3, 2014, Pages 446-452

  Arenz, Stefan ^a   Meydan, Sezen ^b   Starosta, Agata L ^a   Berninghausen, Otto ^a   Beckmann, Roland ^a   Vázquez Laslop, Nora ^b   Wilson, Daniel N ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYL TRANSFER RNA; ERYTHROMYCIN; METHYLTRANSFERASE; PEPTIDYLTRANSFERASE; POLYPEPTIDE; SIGNAL PEPTIDE; BACTERIAL PROTEIN; PEPTIDE FRAGMENT; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; GENE CONTROL; NONHUMAN; PROTEIN SYNTHESIS; RIBOSOME; STAPHYLOCOCCUS AUREUS; SUCROSE GRADIENT; TRANSLATION REGULATION; CHEMICAL STRUCTURE; CHEMISTRY; PHYSIOLOGY; PROTEIN QUATERNARY STRUCTURE;

STAPHYLOCOCCUS AUREUS;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; ERYTHROMYCIN; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES;

EID: 84922433015     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.09.014     Document Type: Article

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