Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

Nature Communications

Volumn 5, Issue , 2014, Pages

  Arenz, Stefan ^a   Ramu, Haripriya ^b   Gupta, Pulkit ^b   Berninghausen, Otto ^a   Beckmann, Roland ^a   Vázquez Laslop, Nora ^b   Mankin, Alexander S ^b   Wilson, Daniel N ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CLINDAMYCIN; ERMBL LEADER PEPTIDE; ERYTHROMYCIN; JOSAMYCIN; OLEANDOMYCIN; PEPTIDYLTRANSFERASE; QUINUPRISTIN; SIGNAL PEPTIDE; SOLITHROMYCIN; TRANSFER RNA; UNCLASSIFIED DRUG; METHYLTRANSFERASE; OLIGONUCLEOTIDE; RRNA (ADENOSINE-O-2'-)METHYLTRANSFERASE;

ANTIBIOTICS; BACTERIUM; BLOOD; ELECTRON MICROSCOPY; GENE EXPRESSION; MOLECULAR ANALYSIS; PEPTIDE; PROTEIN;

AMINOACYLATION; ANTIBIOTIC RESISTANCE; ARTICLE; CELL INTERACTION; COMPLEX FORMATION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ERYTHROMYCIN DEPENDENT RIBOSOME; ESCHERICHIA COLI; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RIBOSOME; RNA TRANSLATION; STALLED RIBOSOME COMPLEX; TRANSLATION REGULATION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; CRYOELECTRON MICROSCOPY; ERYTHROMYCIN; GENE EXPRESSION REGULATION, BACTERIAL; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PROTEIN BIOSYNTHESIS; PROTEIN SORTING SIGNALS; RIBOSOMES;

EID: 84903978452     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4501     Document Type: Article

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