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Volumn 12, Issue 7, 2006, Pages 1262-1270

Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits

Author keywords

30S ribosomal subunit; Antibacterial agents; Translational inhibitors; Translocation

Indexed keywords

ANTIBIOTIC AGENT; GE 82832; LUCIFERASE; NATURAL PRODUCT; PROTEIN INHIBITOR; RIBOSOME PROTEIN; RNA 16S; UNCLASSIFIED DRUG;

EID: 33745608210     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.61206     Document Type: Article
Times cited : (30)

References (35)
  • 1
    • 0032982866 scopus 로고    scopus 로고
    • EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome
    • Agrawal, R.K., Heagle, A.B., Penczek, P., Grassucci, R.A., and Frank, J. 1999. EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome. Nat. Struct. Biol. 6: 643-647.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 643-647
    • Agrawal, R.K.1    Heagle, A.B.2    Penczek, P.3    Grassucci, R.A.4    Frank, J.5
  • 2
    • 0034618071 scopus 로고    scopus 로고
    • Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle
    • Agrawal, R.K., Spahn, C.M., Penczek, P., Grassucci, R.A., Nierhaus, K.H., and Frank, J. 2000. Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J. Cell Biol. 150: 447-460.
    • (2000) J. Cell Biol. , vol.150 , pp. 447-460
    • Agrawal, R.K.1    Spahn, C.M.2    Penczek, P.3    Grassucci, R.A.4    Nierhaus, K.H.5    Frank, J.6
  • 3
    • 30444456799 scopus 로고    scopus 로고
    • Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic
    • Brandi, L., Fabbretti, A., La Teana, A., Abbondi, M., Losi, D., Donadio, S., and Gualerzi, C.O. 2006a. Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic. Proc. Natl. Acad. Sci. 103: 39-44.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 39-44
    • Brandi, L.1    Fabbretti, A.2    La Teana, A.3    Abbondi, M.4    Losi, D.5    Donadio, S.6    Gualerzi, C.O.7
  • 5
    • 0034704217 scopus 로고    scopus 로고
    • The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit
    • Brodersen, D.E., Clemons, W.M., Carter, A.P., Morgan-Warren, R.J., Wimberly, B.T., and Ramakrishnan, V. 2000. The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell 103: 1143-1154.
    • (2000) Cell , vol.103 , pp. 1143-1154
    • Brodersen, D.E.1    Clemons, W.M.2    Carter, A.P.3    Morgan-Warren, R.J.4    Wimberly, B.T.5    Ramakrishnan, V.6
  • 6
    • 0034699519 scopus 로고    scopus 로고
    • Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
    • Carter, A.P., Clemons, W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., and Ramakrishnan, V. 2000. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407: 340-348.
    • (2000) Nature , vol.407 , pp. 340-348
    • Carter, A.P.1    Clemons, W.M.2    Brodersen, D.E.3    Morgan-Warren, R.J.4    Wimberly, B.T.5    Ramakrishnan, V.6
  • 7
    • 0042173407 scopus 로고    scopus 로고
    • Ribosomal proteins S12 and S13 function as control elements for translocation of the mRNA-tRNA complex
    • Cukras, A.R., Southworth, D.R., Brunelle, J.L., Culver, G.M., and Green, R. 2003. Ribosomal proteins S12 and S13 function as control elements for translocation of the mRNA-tRNA complex. Mol. Cell 12: 321-328s.
    • (2003) Mol. Cell , vol.12
    • Cukras, A.R.1    Southworth, D.R.2    Brunelle, J.L.3    Culver, G.M.4    Green, R.5
  • 8
    • 0002331708 scopus 로고
    • Recognition sites for antibiotics within rRNA
    • eds. W.E. Hill et al., ASM Press, Washigton, DC
    • Cundliffe, E. 1990. Recognition sites for antibiotics within rRNA. In The ribosome. Structure, function & evolution (eds. W.E. Hill et al.), pp. 479-490. ASM Press, Washigton, DC.
    • (1990) The Ribosome. Structure, Function & Evolution , pp. 479-490
    • Cundliffe, E.1
  • 9
    • 0025305692 scopus 로고
    • Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16S ribosomal RNA
    • De Stasio, E.A. and Dahlberg, A.E. 1990. Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16S ribosomal RNA. J. Mol. Biol. 212: 127-133.
    • (1990) J. Mol. Biol. , vol.212 , pp. 127-133
    • De Stasio, E.A.1    Dahlberg, A.E.2
  • 10
    • 0031721651 scopus 로고    scopus 로고
    • Effect of temperature on in vivo protein synthetic capacity in Escherichia coli
    • Farewell, A. and Neidhardt, F.C. 1998. Effect of temperature on in vivo protein synthetic capacity in Escherichia coli. J. Bacteriol. 180: 4704-4710.
    • (1998) J. Bacteriol. , vol.180 , pp. 4704-4710
    • Farewell, A.1    Neidhardt, F.C.2
  • 11
    • 0028889120 scopus 로고
    • Contribution of cotranslational folding to the rate of formation of native protein structure
    • Fedorov, A.N. and Baldwin, T.O. 1995. Contribution of cotranslational folding to the rate of formation of native protein structure. Proc. Natl. Acad. Sci. 92: 1227-1231.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 1227-1231
    • Fedorov, A.N.1    Baldwin, T.O.2
  • 12
    • 0034691576 scopus 로고    scopus 로고
    • A ratchet-like intersubunit reorganization of the ribosome during translocation
    • Frank, J. and Agrawal, R.K. 2000. A ratchet-like intersubunit reorganization of the ribosome during translocation. Nature 406: 318-322.
    • (2000) Nature , vol.406 , pp. 318-322
    • Frank, J.1    Agrawal, R.K.2
  • 15
    • 84886634813 scopus 로고
    • Factor-free ("non-enzymic") and factor-dependent systems of translation of polyuridylic acid by Escherichia coli ribosomes
    • Gavrilova, L.P., Kostiashkina, V.E., Rutkevitch, N.M., and Spirin, A.S. 1976. Factor-free ("non-enzymic") and factor-dependent systems of translation of polyuridylic acid by Escherichia coli ribosomes. J. Mol. Biol. 101: 537-552.
    • (1976) J. Mol. Biol. , vol.101 , pp. 537-552
    • Gavrilova, L.P.1    Kostiashkina, V.E.2    Rutkevitch, N.M.3    Spirin, A.S.4
  • 16
    • 0034595692 scopus 로고    scopus 로고
    • Co-translational folding of an eukaryotic multidomain protein in a prokaryotic translation system
    • Kolb, V.A., Makeyev, E.V., and Spirin, A.S. 2000. Co-translational folding of an eukaryotic multidomain protein in a prokaryotic translation system. J. Biol. Chem. 275: 16597-16601.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16597-16601
    • Kolb, V.A.1    Makeyev, E.V.2    Spirin, A.S.3
  • 17
    • 0027151981 scopus 로고
    • Translation of mRNAs with degenerate initiation triplet AUU displays high initiation factor 2 dependence and is subject to initiation factor 3 repression
    • La Teana, A., Pon, C.L., and Gualerzi, C.O. 1993. Translation of mRNAs with degenerate initiation triplet AUU displays high initiation factor 2 dependence and is subject to initiation factor 3 repression. Proc. Natl. Acad. Sci. 90: 4161-4165.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 4161-4165
    • La Teana, A.1    Pon, C.L.2    Gualerzi, C.O.3
  • 18
    • 33745632844 scopus 로고
    • Dinucleotide codon-anticodon interaction as a minimum requirement for ribosomal aa-tRNA binding: Stabilisation by viomycin of aa-tRNA in the A site
    • Luehrmann, R. 1980. Dinucleotide codon-anticodon interaction as a minimum requirement for ribosomal aa-tRNA binding: Stabilisation by viomycin of aa-tRNA in the A site. Nucleic Acids Res. 58: 13-24.
    • (1980) Nucleic Acids Res. , vol.58 , pp. 13-24
    • Luehrmann, R.1
  • 19
    • 0033032414 scopus 로고    scopus 로고
    • Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors
    • Matassova, N.B., Rodnina, M.V., Endermann, R., Kroll, H.P., Pleiss, U., Wild, H., and Wintermeyer, W. 1999. Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA 5: 939-946.
    • (1999) RNA , vol.5 , pp. 939-946
    • Matassova, N.B.1    Rodnina, M.V.2    Endermann, R.3    Kroll, H.P.4    Pleiss, U.5    Wild, H.6    Wintermeyer, W.7
  • 20
    • 0033534197 scopus 로고    scopus 로고
    • Nucleotides in 16S rRNA Protected by the association of 30S and 50S ribosomal subunits
    • Merryman, C., Moazed, D., McWhirter, J., and Noller, H.F. 1999. Nucleotides in 16S rRNA Protected by the association of 30S and 50S ribosomal subunits. J. Mol. Biol. 285: 97-105.
    • (1999) J. Mol. Biol. , vol.285 , pp. 97-105
    • Merryman, C.1    Moazed, D.2    McWhirter, J.3    Noller, H.F.4
  • 21
    • 0023604799 scopus 로고
    • Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
    • Moazed, D. and Noller, H.F. 1987. Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie 69: 879-884.
    • (1987) Biochimie , vol.69 , pp. 879-884
    • Moazed, D.1    Noller, H.F.2
  • 22
    • 0022470564 scopus 로고
    • Rapid chemical probing of conformation in 16 S ribosomal RNA and 30S ribosomal subunits using primer extension
    • Moazed, D., Stern, S., and Noller, H.F. 1986. Rapid chemical probing of conformation in 16 S ribosomal RNA and 30S ribosomal subunits using primer extension. J. Mol. Biol. 187: 399-416.
    • (1986) J. Mol. Biol. , vol.187 , pp. 399-416
    • Moazed, D.1    Stern, S.2    Noller, H.F.3
  • 24
    • 6344252614 scopus 로고    scopus 로고
    • Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation
    • Peske, F., Savelsbergh, A.K., Rodnina, M.V., and Wintermeyer, W. 2004. Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation. J. Mol. Biol. 343: 1183-1194.
    • (2004) J. Mol. Biol. , vol.343 , pp. 1183-1194
    • Peske, F.1    Savelsbergh, A.K.2    Rodnina, M.V.3    Wintermeyer, W.4
  • 26
    • 0038433302 scopus 로고    scopus 로고
    • An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation
    • Savelsbergh, A., Katunin, V.I., Mohr, D., Peske, F., Rodnina, M.V., and Wintermeyer, W. 2003. An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation. Mol. Cell 11: 1517-1523.
    • (2003) Mol. Cell , vol.11 , pp. 1517-1523
    • Savelsbergh, A.1    Katunin, V.I.2    Mohr, D.3    Peske, F.4    Rodnina, M.V.5    Wintermeyer, W.6
  • 28
    • 0034603196 scopus 로고    scopus 로고
    • Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation
    • Stark, H., Rodnina, M.V., Wieden, H.-J., van Heel, M., and Wintermeyer, W. 2000. Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation. Cell 100: 301-309.
    • (2000) Cell , vol.100 , pp. 301-309
    • Stark, H.1    Rodnina, M.V.2    Wieden, H.-J.3    Van Heel, M.4    Wintermeyer, W.5
  • 29
    • 0034624039 scopus 로고    scopus 로고
    • Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation
    • van Loock, M.S., Agrawal, R.K., Gabashvili, I.S., Qi, L., Frank, J., and Harvey, S.C. 2000. Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation. J. Mol. Biol. 304: 507-515.
    • (2000) J. Mol. Biol. , vol.304 , pp. 507-515
    • Van Loock, M.S.1    Agrawal, R.K.2    Gabashvili, I.S.3    Qi, L.4    Frank, J.5    Harvey, S.C.6
  • 30
    • 0035986708 scopus 로고    scopus 로고
    • Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site
    • Vicens, Q. and Westhof, E. 2002. Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site. Chem. Biol. 9: 747-755.
    • (2002) Chem. Biol. , vol.9 , pp. 747-755
    • Vicens, Q.1    Westhof, E.2
  • 31
    • 0042337397 scopus 로고    scopus 로고
    • Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: An analysis of x-ray crystal structures
    • Vicens, Q. and Westhof, E. 2003. Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: An analysis of x-ray crystal structures. Biopolymers 70: 42-57.
    • (2003) Biopolymers , vol.70 , pp. 42-57
    • Vicens, Q.1    Westhof, E.2
  • 33
  • 34
    • 84955162315 scopus 로고    scopus 로고
    • Antibiotics and the inhibition of ribosome function
    • eds. K. Nierhaus and D.N. Wilson, Wiley-VSH Verlag, Weinheim, Germany
    • Wilson, D.N. 2004. Antibiotics and the inhibition of ribosome function. In Protein synthesis and ribosome structure (eds. K. Nierhaus and D.N. Wilson), pp. 449-519. Wiley-VSH Verlag, Weinheim, Germany.
    • (2004) Protein Synthesis and Ribosome Structure , pp. 449-519
    • Wilson, D.N.1
  • 35
    • 0019192572 scopus 로고
    • The translocation inhibitor tuberactinomycin binds to nucleic acids and blocks the in vitro assembly of 50S subunits
    • Yamada, T., Teshima, T., Shiba, T., and Nierhaus, K.H. 1980. The translocation inhibitor tuberactinomycin binds to nucleic acids and blocks the in vitro assembly of 50S subunits. Nucleic Acids Res. 8: 5767-5777.
    • (1980) Nucleic Acids Res. , vol.8 , pp. 5767-5777
    • Yamada, T.1    Teshima, T.2    Shiba, T.3    Nierhaus, K.H.4


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