-
1
-
-
84861974512
-
The Prdm family: expanding roles in stem cells and development
-
Hohenauer T., Moore A.W. The Prdm family: expanding roles in stem cells and development. Development 2012, 139:2267-2282.
-
(2012)
Development
, vol.139
, pp. 2267-2282
-
-
Hohenauer, T.1
Moore, A.W.2
-
2
-
-
83455259343
-
PRDM proteins: Important players in differentiation and disease
-
Fog C.K., et al. PRDM proteins: Important players in differentiation and disease. Bioessays 2012, 34:50-60.
-
(2012)
Bioessays
, vol.34
, pp. 50-60
-
-
Fog, C.K.1
-
3
-
-
42649120075
-
Regulation and functions of Blimp-1 in T and B lymphocytes
-
Martins G., Calame K. Regulation and functions of Blimp-1 in T and B lymphocytes. Annu. Rev. Immunol. 2008, 26:133-169.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 133-169
-
-
Martins, G.1
Calame, K.2
-
4
-
-
84055187645
-
PRDM1 is a tumor suppressor gene in natural killer cell malignancies
-
Küçük C., et al. PRDM1 is a tumor suppressor gene in natural killer cell malignancies. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:20119-20124.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 20119-20124
-
-
Küçük, C.1
-
5
-
-
84884160850
-
Induction of mouse germ-cell fate by transcription factors in vitro
-
Nakaki F., et al. Induction of mouse germ-cell fate by transcription factors in vitro. Nature 2013, 501:222-226.
-
(2013)
Nature
, vol.501
, pp. 222-226
-
-
Nakaki, F.1
-
6
-
-
84871133298
-
Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation
-
Chittka A., et al. Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation. J. Biol. Chem. 2012, 287:42995-43006.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 42995-43006
-
-
Chittka, A.1
-
7
-
-
84940589660
-
Deletion of Prdm8 impairs development of upper-layer neocortical neurons
-
Inoue M., et al. Deletion of Prdm8 impairs development of upper-layer neocortical neurons. Genes Cells 2015, 20:758-770.
-
(2015)
Genes Cells
, vol.20
, pp. 758-770
-
-
Inoue, M.1
-
8
-
-
84900394917
-
Prdm8 regulates the morphological transition at multipolar phase during neocortical development
-
Inoue M., et al. Prdm8 regulates the morphological transition at multipolar phase during neocortical development. PLoS ONE 2014, 9:e86356.
-
(2014)
PLoS ONE
, vol.9
, pp. e86356
-
-
Inoue, M.1
-
9
-
-
84863011484
-
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
-
Ross S.E., et al. Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron 2012, 73:292-303.
-
(2012)
Neuron
, vol.73
, pp. 292-303
-
-
Ross, S.E.1
-
10
-
-
84943537747
-
The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception
-
Nagy V., et al. The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception. Cell Cycle 2015, 14:1799-1808.
-
(2015)
Cell Cycle
, vol.14
, pp. 1799-1808
-
-
Nagy, V.1
-
11
-
-
84933279454
-
Transcriptional regulator PRDM12 is essential for human pain perception
-
Chen Y-C., et al. Transcriptional regulator PRDM12 is essential for human pain perception. Nat. Genet. 2015, 47:803-808.
-
(2015)
Nat. Genet.
, vol.47
, pp. 803-808
-
-
Chen, Y.-C.1
-
12
-
-
84943520196
-
Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus
-
Thélie A., et al. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development 2015, 142:3416-3428.
-
(2015)
Development
, vol.142
, pp. 3416-3428
-
-
Thélie, A.1
-
13
-
-
84877003488
-
Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits
-
Chang J.C., et al. Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits. Dev. Cell 2013, 25:182-195.
-
(2013)
Dev. Cell
, vol.25
, pp. 182-195
-
-
Chang, J.C.1
-
14
-
-
84892867335
-
The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube
-
Hanotel J., et al. The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube. Dev. Biol. 2014, 386:340-357.
-
(2014)
Dev. Biol.
, vol.386
, pp. 340-357
-
-
Hanotel, J.1
-
15
-
-
84929691973
-
Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity
-
Watanabe S., et al. Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. J. Neurosci. 2015, 35:8004-8020.
-
(2015)
J. Neurosci.
, vol.35
, pp. 8004-8020
-
-
Watanabe, S.1
-
16
-
-
33947108472
-
RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines
-
Pastural E., et al. RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines. Oncogene 2006, 26:1586-1594.
-
(2006)
Oncogene
, vol.26
, pp. 1586-1594
-
-
Pastural, E.1
-
17
-
-
84874764746
-
Retinoblastoma protein-interacting zinc-finger gene 1 (RIZ1) dysregulation in human malignant meningiomas
-
Liu Z.Y., et al. Retinoblastoma protein-interacting zinc-finger gene 1 (RIZ1) dysregulation in human malignant meningiomas. Oncogene 2013, 32:1216-1222.
-
(2013)
Oncogene
, vol.32
, pp. 1216-1222
-
-
Liu, Z.Y.1
-
18
-
-
80555154347
-
The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating wnt/β-catenin signaling and is frequently silenced in multiple tumors
-
Shu X., et al. The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating wnt/β-catenin signaling and is frequently silenced in multiple tumors. PLoS ONE 2011, 6:e27346.
-
(2011)
PLoS ONE
, vol.6
, pp. e27346
-
-
Shu, X.1
-
19
-
-
84865680532
-
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity
-
Pinheiro I., et al. Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity. Cell 2012, 150:948-960.
-
(2012)
Cell
, vol.150
, pp. 948-960
-
-
Pinheiro, I.1
-
20
-
-
0345275880
-
Inactivation of a histone methyltransferase by mutations in human cancers
-
Kim K-C., et al. Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res. 2003, 63:7619-7623.
-
(2003)
Cancer Res.
, vol.63
, pp. 7619-7623
-
-
Kim, K.-C.1
-
21
-
-
68949148757
-
Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis
-
Eom G.H., et al. Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis. Biochem. Biophys. Res. Commun. 2009, 388:131-136.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.388
, pp. 131-136
-
-
Eom, G.H.1
-
22
-
-
84885867381
-
Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9
-
Wu H., et al. Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9. Cell Rep. 2013, 5:13-20.
-
(2013)
Cell Rep.
, vol.5
, pp. 13-20
-
-
Wu, H.1
-
23
-
-
37549072290
-
PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation
-
Wu Y., et al. PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. J. Mol. Cell. Cardiol. 2008, 44:47-58.
-
(2008)
J. Mol. Cell. Cardiol.
, vol.44
, pp. 47-58
-
-
Wu, Y.1
-
24
-
-
1542347557
-
PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing
-
Győry I., et al. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nat. Immunol. 2004, 5:299-308.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 299-308
-
-
Gyory, I.1
-
25
-
-
33744795753
-
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells
-
Ancelin K., et al. Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat. Cell Biol. 2006, 8:623-630.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 623-630
-
-
Ancelin, K.1
-
26
-
-
0142183452
-
A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation
-
Nishikata I., et al. A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation. Blood 2003, 102:3323-3332.
-
(2003)
Blood
, vol.102
, pp. 3323-3332
-
-
Nishikata, I.1
-
27
-
-
34347326271
-
Transcriptional control of brown fat determination by PRDM16
-
Seale P., et al. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 2007, 6:38-54.
-
(2007)
Cell Metab.
, vol.6
, pp. 38-54
-
-
Seale, P.1
-
28
-
-
84892727198
-
What we talk about when we talk about fat
-
Rosen E.D., Spiegelman B.M. What we talk about when we talk about fat. Cell 2014, 156:20-44.
-
(2014)
Cell
, vol.156
, pp. 20-44
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
29
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz P., et al. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 1994, 79:1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
-
30
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P., et al. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92:829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
-
31
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry M., et al. Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 2006, 3:333-341.
-
(2006)
Cell Metab.
, vol.3
, pp. 333-341
-
-
Uldry, M.1
-
32
-
-
50049122271
-
PRDM16 controls a brown fat/skeletal muscle switch
-
Seale P., et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 2008, 454:961-967.
-
(2008)
Nature
, vol.454
, pp. 961-967
-
-
Seale, P.1
-
33
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu J., et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 2012, 150:366-376.
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
-
34
-
-
84962076500
-
Brown and beige fat: molecular parts of a thermogenic machine
-
Cohen P., Spiegelman B.M. Brown and beige fat: molecular parts of a thermogenic machine. Diabetes 2015, 64:2346-2351.
-
(2015)
Diabetes
, vol.64
, pp. 2346-2351
-
-
Cohen, P.1
Spiegelman, B.M.2
-
35
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale P., et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J. Clin. Invest. 2011, 121:96-105.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 96-105
-
-
Seale, P.1
-
36
-
-
84892702771
-
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch
-
Cohen P., et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell 2014, 156:304-316.
-
(2014)
Cell
, vol.156
, pp. 304-316
-
-
Cohen, P.1
-
37
-
-
84897525104
-
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice
-
Harms M.J., et al. Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014, 19:593-604.
-
(2014)
Cell Metab.
, vol.19
, pp. 593-604
-
-
Harms, M.J.1
-
38
-
-
44149113548
-
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
-
Kajimura S., et al. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev. 2008, 22:1397-1409.
-
(2008)
Genes Dev.
, vol.22
, pp. 1397-1409
-
-
Kajimura, S.1
-
39
-
-
69349088117
-
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex
-
Kajimura S., et al. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex. Nature 2009, 460:1154-1158.
-
(2009)
Nature
, vol.460
, pp. 1154-1158
-
-
Kajimura, S.1
-
40
-
-
84889604511
-
EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex
-
Ohno H., et al. EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex. Nature 2013, 504:163-167.
-
(2013)
Nature
, vol.504
, pp. 163-167
-
-
Ohno, H.1
-
41
-
-
84921538870
-
Cold-onducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat
-
Dempersmier J., et al. Cold-onducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat. Mol. Cell 2015, 57:235-246.
-
(2015)
Mol. Cell
, vol.57
, pp. 235-246
-
-
Dempersmier, J.1
-
42
-
-
84875358826
-
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs
-
Villanueva C.J., et al. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. Cell Metab. 2013, 17:423-435.
-
(2013)
Cell Metab.
, vol.17
, pp. 423-435
-
-
Villanueva, C.J.1
-
43
-
-
84944180425
-
PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program
-
Harms M.J., et al. PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program. Genes Dev. 2015, 29:298-307.
-
(2015)
Genes Dev.
, vol.29
, pp. 298-307
-
-
Harms, M.J.1
-
44
-
-
84961289743
-
PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1
-
Iida S., et al. PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1. Genes Dev. 2015, 29:308-321.
-
(2015)
Genes Dev.
, vol.29
, pp. 308-321
-
-
Iida, S.1
-
45
-
-
84870595878
-
MyomiR-133 regulates brown fat differentiation through Prdm16
-
Trajkovski M., et al. MyomiR-133 regulates brown fat differentiation through Prdm16. Nat. Cell Biol. 2012, 14:1330-1335.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1330-1335
-
-
Trajkovski, M.1
-
46
-
-
84880812042
-
MiR-133a regulates adipocyte browning in vivo
-
Liu W., et al. miR-133a regulates adipocyte browning in vivo. PLoS Genet. 2013, 9:e1003626.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003626
-
-
Liu, W.1
-
47
-
-
84873327762
-
MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16
-
Yin H., et al. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab. 2013, 17:210-224.
-
(2013)
Cell Metab.
, vol.17
, pp. 210-224
-
-
Yin, H.1
-
48
-
-
84901372739
-
KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression
-
Chou C-F., et al. KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression. Diabetes 2014, 63:2949-2961.
-
(2014)
Diabetes
, vol.63
, pp. 2949-2961
-
-
Chou, C.-F.1
-
49
-
-
84892678138
-
MiR-27 orchestrates the transcriptional regulation of brown adipogenesis
-
Sun L., Trajkovski M. MiR-27 orchestrates the transcriptional regulation of brown adipogenesis. Metabolism 2014, 63:272-282.
-
(2014)
Metabolism
, vol.63
, pp. 272-282
-
-
Sun, L.1
Trajkovski, M.2
-
50
-
-
79960984113
-
Mir193b-365 is essential for brown fat differentiation
-
Sun L., et al. Mir193b-365 is essential for brown fat differentiation. Nat. Cell Biol. 2011, 13:958-965.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 958-965
-
-
Sun, L.1
-
51
-
-
77957551487
-
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
-
Chuikov S., et al. Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 2010, 12:999-1006.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 999-1006
-
-
Chuikov, S.1
-
52
-
-
79955974326
-
Prdm16 is a physiologic regulator of hematopoietic stem cells
-
Aguilo F., et al. Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood 2011, 117:5057-5066.
-
(2011)
Blood
, vol.117
, pp. 5057-5066
-
-
Aguilo, F.1
-
53
-
-
77950526610
-
Prdm16 is required for normal palatogenesis in mice
-
Bjork B.C., et al. Prdm16 is required for normal palatogenesis in mice. Hum. Mol. Genet. 2010, 19:774-789.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 774-789
-
-
Bjork, B.C.1
-
54
-
-
84880268274
-
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy
-
Arndt A-K., et al. Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am. J. Hum. Genet. 2013, 93:67-77.
-
(2013)
Am. J. Hum. Genet.
, vol.93
, pp. 67-77
-
-
Arndt, A.-K.1
-
55
-
-
84898667019
-
Identification of critical regions and candidate genes for cardiovascular malformations and cardiomyopathy associated with deletions of chromosome 1p36
-
Zaveri H.P., et al. Identification of critical regions and candidate genes for cardiovascular malformations and cardiomyopathy associated with deletions of chromosome 1p36. PLoS ONE 2014, 9:e85600.
-
(2014)
PLoS ONE
, vol.9
, pp. e85600
-
-
Zaveri, H.P.1
-
56
-
-
83555164871
-
PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies: PRDM16 (1p36) translocations
-
Duhoux F.P., et al. PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies: PRDM16 (1p36) translocations. Br. J. Haematol. 2012, 156:76-88.
-
(2012)
Br. J. Haematol.
, vol.156
, pp. 76-88
-
-
Duhoux, F.P.1
-
57
-
-
84904069664
-
Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del (5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts
-
Masetti R., et al. Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del (5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts. Br. J. Haematol. 2014, 166:449-452.
-
(2014)
Br. J. Haematol.
, vol.166
, pp. 449-452
-
-
Masetti, R.1
-
58
-
-
25844450207
-
NovelRUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22)
-
Sakai I., et al. NovelRUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22). Genes. Chromosomes Cancer 2005, 44:265-270.
-
(2005)
Genes. Chromosomes Cancer
, vol.44
, pp. 265-270
-
-
Sakai, I.1
-
59
-
-
33744502344
-
Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t (1; 21)(p36; q22)-positive therapy-related AML
-
Stevens-Kroef M.P., et al. Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t (1; 21)(p36; q22)-positive therapy-related AML. Leukemia 2006, 20:1187-1189.
-
(2006)
Leukemia
, vol.20
, pp. 1187-1189
-
-
Stevens-Kroef, M.P.1
-
60
-
-
0034332196
-
A novel gene, MEL1, mapped to 1p36. 3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t (1; 3)(p36; q21)-positive leukemia cells
-
Mochizuki N., et al. A novel gene, MEL1, mapped to 1p36. 3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t (1; 3)(p36; q21)-positive leukemia cells. Blood 2000, 96:3209-3214.
-
(2000)
Blood
, vol.96
, pp. 3209-3214
-
-
Mochizuki, N.1
-
61
-
-
30144431840
-
MEL1S, not MEL1, is overexpressed in myelodysplastic syndromes patients with t(1;3)(p36;q21)
-
Xiao Z., et al. MEL1S, not MEL1, is overexpressed in myelodysplastic syndromes patients with t(1;3)(p36;q21). Leuk. Res. 2006, 30:332-334.
-
(2006)
Leuk. Res.
, vol.30
, pp. 332-334
-
-
Xiao, Z.1
-
62
-
-
1642398688
-
Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells
-
Yoshida M., et al. Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells. Blood 2004, 103:2753-2760.
-
(2004)
Blood
, vol.103
, pp. 2753-2760
-
-
Yoshida, M.1
-
63
-
-
36849080028
-
Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice
-
Shing D.C., et al. Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice. J. Clin. Invest. 2007, 117:3696-3707.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3696-3707
-
-
Shing, D.C.1
-
64
-
-
80053593820
-
Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation
-
Nishikata I., et al. Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation. Oncogene 2011, 30:4194-4207.
-
(2011)
Oncogene
, vol.30
, pp. 4194-4207
-
-
Nishikata, I.1
-
65
-
-
84908613134
-
Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo
-
Yu H., et al. Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo. Blood 2014, 124:1737-1747.
-
(2014)
Blood
, vol.124
, pp. 1737-1747
-
-
Yu, H.1
-
66
-
-
84929262244
-
High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML
-
Jo A., et al. High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML. Leukemia 2015, 29:1076-1083.
-
(2015)
Leukemia
, vol.29
, pp. 1076-1083
-
-
Jo, A.1
-
67
-
-
84900033263
-
The role of EVI1 in myeloid malignancies
-
Glass C., et al. The role of EVI1 in myeloid malignancies. Blood Cells Mol. Dis. 2014, 53:67-76.
-
(2014)
Blood Cells Mol. Dis.
, vol.53
, pp. 67-76
-
-
Glass, C.1
-
68
-
-
84864315640
-
Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis
-
Kataoka K., Kurokawa M. Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis. Cancer Sci. 2012, 103:1371-1377.
-
(2012)
Cancer Sci.
, vol.103
, pp. 1371-1377
-
-
Kataoka, K.1
Kurokawa, M.2
-
69
-
-
59149091641
-
SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells
-
Takahata M., et al. SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. J. Biol. Chem. 2009, 284:3334-3344.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3334-3344
-
-
Takahata, M.1
-
70
-
-
34249676875
-
PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue
-
Warner D.R., et al. PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue. Biochim. Biophys. Acta 2007, 1773:814-820.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 814-820
-
-
Warner, D.R.1
-
71
-
-
0035353203
-
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling
-
Izutsu K., et al. The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling. Blood 2001, 97:2815-2822.
-
(2001)
Blood
, vol.97
, pp. 2815-2822
-
-
Izutsu, K.1
-
72
-
-
0033014867
-
MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1
-
Sood R., et al. MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1. Leukemia 1999, 13:348-357.
-
(1999)
Leukemia
, vol.13
, pp. 348-357
-
-
Sood, R.1
-
73
-
-
84858039282
-
PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein
-
Ohno H., et al. PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein. Cell Metab. 2012, 15:395-404.
-
(2012)
Cell Metab.
, vol.15
, pp. 395-404
-
-
Ohno, H.1
-
74
-
-
84906934662
-
Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
-
Kir S., et al. Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia. Nature 2014, 513:100-104.
-
(2014)
Nature
, vol.513
, pp. 100-104
-
-
Kir, S.1
-
75
-
-
84913602920
-
A wwitch from white to brown fat increases energy expenditure in cancer-associated cachexia
-
Petruzzelli M., et al. A wwitch from white to brown fat increases energy expenditure in cancer-associated cachexia. Cell Metab. 2014, 20:433-447.
-
(2014)
Cell Metab.
, vol.20
, pp. 433-447
-
-
Petruzzelli, M.1
-
76
-
-
84865489581
-
Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis
-
Chang L., et al. Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis. Circulation 2012, 126:1067-1078.
-
(2012)
Circulation
, vol.126
, pp. 1067-1078
-
-
Chang, L.1
-
77
-
-
84879846992
-
Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis
-
Dong M., et al. Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis. Cell Metab. 2013, 18:118-129.
-
(2013)
Cell Metab.
, vol.18
, pp. 118-129
-
-
Dong, M.1
-
78
-
-
3543033990
-
A histone methyltransferase is required for maximal response to female sex hormones
-
Carling T., et al. A histone methyltransferase is required for maximal response to female sex hormones. Mol. Cell. Biol. 2004, 24:7032-7042.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7032-7042
-
-
Carling, T.1
-
79
-
-
48149095026
-
Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells
-
Goyama S., et al. Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells. Cell Stem Cell 2008, 3:207-220.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 207-220
-
-
Goyama, S.1
-
80
-
-
84862908988
-
Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity
-
Kataoka K., et al. Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity. J. Exp. Med. 2011, 208:2403-2416.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2403-2416
-
-
Kataoka, K.1
-
81
-
-
0034660525
-
The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death
-
Kurokawa M., et al. The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death. EMBO J. 2000, 19:2958-2968.
-
(2000)
EMBO J.
, vol.19
, pp. 2958-2968
-
-
Kurokawa, M.1
-
82
-
-
1842456983
-
The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E
-
Chittka A. The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. J. Cell Biol. 2004, 164:985-996.
-
(2004)
J. Cell Biol.
, vol.164
, pp. 985-996
-
-
Chittka, A.1
-
83
-
-
34748897679
-
Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5
-
Duan Z., et al. Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5. Mol. Cell. Biol. 2007, 27:6889-6902.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6889-6902
-
-
Duan, Z.1
-
84
-
-
79958826990
-
Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance
-
Burkitt Wright E.M.M., et al. Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance. Am. J. Hum. Genet. 2011, 88:767-777.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 767-777
-
-
Burkitt Wright, E.M.M.1
-
85
-
-
59249091253
-
The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development
-
Meani N., et al. The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development. PLoS ONE 2009, 4:e4273.
-
(2009)
PLoS ONE
, vol.4
, pp. e4273
-
-
Meani, N.1
-
86
-
-
33645239290
-
PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells
-
Davis C.A., et al. PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol. Cell. Biol. 2006, 26:2626-2636.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2626-2636
-
-
Davis, C.A.1
-
87
-
-
84931287869
-
Transcription factor PRDM8 is required for rod bipolar and type 2 OFF-cone bipolar cell survival and amacrine subtype identity
-
Jung C.C., et al. Transcription factor PRDM8 is required for rod bipolar and type 2 OFF-cone bipolar cell survival and amacrine subtype identity. Proc. Natl. Acad. Sci. U.S.A. 2015, 112:E3010-E3019.
-
(2015)
Proc. Natl. Acad. Sci. U.S.A.
, vol.112
, pp. E3010-E3019
-
-
Jung, C.C.1
-
88
-
-
27844440989
-
A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
-
Hayashi K., et al. A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature 2005, 438:374-378.
-
(2005)
Nature
, vol.438
, pp. 374-378
-
-
Hayashi, K.1
-
89
-
-
76749170346
-
PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice
-
Baudat F., et al. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science 2010, 327:836-840.
-
(2010)
Science
, vol.327
, pp. 836-840
-
-
Baudat, F.1
-
90
-
-
77951920367
-
Expression patterns of PRDM10 during mouse embryonic development
-
Park J-A., Kim K-C. Expression patterns of PRDM10 during mouse embryonic development. BMB Rep. 2010, 43:29-33.
-
(2010)
BMB Rep.
, vol.43
, pp. 29-33
-
-
Park, J.-A.1
Kim, K.-C.2
-
91
-
-
84923365961
-
Loss of PRDM11 promotes MYC-driven lymphomagenesis
-
Fog C.K., et al. Loss of PRDM11 promotes MYC-driven lymphomagenesis. Blood 2015, 125:1272-1281.
-
(2015)
Blood
, vol.125
, pp. 1272-1281
-
-
Fog, C.K.1
-
92
-
-
84924266513
-
Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity
-
Satoh A., et al. Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity. Aging Cell 2015, 14:209-218.
-
(2015)
Aging Cell
, vol.14
, pp. 209-218
-
-
Satoh, A.1
-
93
-
-
84901190070
-
PRDM14: a unique regulator for pluripotency and epigenetic reprogramming
-
Nakaki F., Saitou M. PRDM14: a unique regulator for pluripotency and epigenetic reprogramming. Trends Biochem. Sci. 2014, 39:289-298.
-
(2014)
Trends Biochem. Sci.
, vol.39
, pp. 289-298
-
-
Nakaki, F.1
Saitou, M.2
|