RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines

Oncogene

Volumn 26, Issue 11, 2007, Pages 1586-1594

  Pastural, E ^a   Takahashi, N ^a   Dong, W F ^a   Bainbridge, M ^a   Hull, A ^a   Pearson, D ^a   Huang, S ^b   Lowsky, R ^a,c   DeCoteau, J F ^a,d   Geyer, C R ^a,d  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b BURNHAM INSTITUTE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Saskatoon Cancer Center   (Canada)

Author keywords

Chronic myeloid leukemia; Histone methyltransferase; IGF 1; RIZ1

Indexed keywords

COMPLEMENTARY DNA; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE RIZ1; SOMATOMEDIN C; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLAST TRANSFORMATION; CANCER CELL; CANCER INHIBITION; CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DNA MICROARRAY; ENZYME REPRESSION; HETEROZYGOSITY; HUMAN; HUMAN CELL; METASTASIS INHIBITION; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HISTONES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; LYSINE; METHYLATION; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 33947108472     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209959     Document Type: Article

References (34)

1. Abbondanza C, Medici N, Nigro V, Rossi V, Gallo L, Piluso G et al. (2000). The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action. Proc Natl Acad Sci USA 97: 3130-3135.
2. Aro AL, Savikko J, Pulkkinen V, von Willebrand E. (2002). Expression of insulin-like growth factors IGF-I and IGF-II, and their receptors during the growth and megakaryocytic differentiation of K562cells. Leuk Res 26: 831-837.
3. Buyse I, Shao G, Huang S. (1995). The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Proc Natl Acad Sci USA 92: 4467-4471.
4. Calabretta B, Perrotti D. (2004). The biology of CML blast crisis. Blood 103: 4010-4022.
5. Carling T, Kim KC, Yang XH, Gu J, Zhang XK, Huang S. (2004). A histone methyltransferase is required for maximal response to female sex hormones. Mol Cell Biol 24: 7032-7042.
6. Chadwick RB, Jiang GL, Bennington GA, Yuan B, Johnson CK, Stevens MW et al. (2000). Candidate tumor suppressor RIZ is frequently involved in colorectral carcinogenesis. Proc Natl Acad Sci USA 97: 2662-2667.
7. Chang HW, Chan A, Kwang DL, Wei WI, Sham JS, Yuen AP. (2004). Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric cancer. Int J Cancer 110: 212-218.
8. Dong WF, Scott SA, Guo Y, Bergen SP, Sheridan DP, DeCoteau JF. (2003). RIZ1, a protein/histone methyltransferase superfamily member, is epigenetically silenced in human AML and its constitutive expression promotes apoptosis and differentiation. Blood 102: 579-580.
9. Du Y, Carling T, Fang W, Piao Z, Sheu JC, Huang S. (2001). Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res 61: 8094-8099.
10. Endo K, Harigae H, Nagai T, Fujie H, Meguro K, Watanabe N et al. (1993). Two chronic myelogenous leukaemia cell lines which represent different stages of erythroid differentiation. Br J Hematol 85: 653-662.
11. Francki A, Motamed K, McClure TD, Kaya M, Murri C, Blake DJ et al. (2003). SPARC regulates cell cycle progression in mesangial cells via its inhibition of IGF-dependent signaling. J Cell Biochem 88: 802-811.
12. Gazzerro P, Abbondanza C, D'Arcangelo A, Rossi M, Medici N, Moncharmont B et al. (2006). Modulation of RIZ gene expression is associated to estradiol control of MCF-7 breast cancer cell proliferation. Exp Cell Res 312: 340-349.
13. Hicks DG, Ohlsson-Wilhelm BM, Farley BA, Kosciolek BA, Rowley PT. (1985). K562 cell erythroid differentiation: requirement for factor in fetal bovine serum. Exp Hematol 13: 273-280.
14. Hoeflich A, Reisinger R, Lahm H, Kiess W, Blum WF, Kolb HJ et al. (2001). Insulin-like growth factor-binding protein 2 in tumorigenesis: protector or promoter? Cancer Res 61: 8601-8610.
15. Huang S, Shao G, Liu L. (1998). The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem 273: 15933-15939.
16. Kang CD, Do I, Kim K, Ahn B, Kim S, Chung B et al. (1999). Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells. Exp Mol Med 31: 76-82.
17. Kim D, Liqing G, Huang S. (2003). Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res 63: 7619-7623.
18. Liu L, Shao G, Steele-Perkins G, Huang S. (1997). The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter. J Biol Chem 272: 2984-2991.
19. Medici N, Abbondanza C, Nigro V, Rossi V, Piluso G, Belsito A et al. (1999). Identification of a DNA binding protein cooperating with estrogen receptor as RIZ (retinoblastoma interacting zinc finger protein). Biochem Biophys Res Commun 264: 983-989.
20. Mori N, Morosetti R, Spira S, Lee S, Ben-Yehuda D, Schiller G et al. (1998). Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelocytic leukemia. Blood 92: 3405-3409.
21. Muraosa Y, Takahashi K, Yoshizawa M, Shibahara S. (1996). cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Eur J Biochem 235: 471-479.
22. Pepe MG, Ginzton NH, Lee PD, Hintz RL, Greenberg PL. (1987). Receptor binding and mitogenic effects of insulin and insulin-like growth factors I and II for human myeloid leukemic cells. J Cell Physiol 133: 219-227.
23. Piao Z, Fang W, Malkhosyan S, Kim H, Horii A, Perucho M et al. (2000). Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability. Cancer Res 60: 4701-4704.
24. Ribadeau Dumas A, Hamouda NB, Leriche L, Piffaut MC, Bonnemye P, Kuen RL et al. (2004). Establishment and characterization of a new human erythroleukemic cell line, ERY-1. Leuk Res 28: 1329-1339.
25. Rutherford TR, Clegg JB, Weatherall DJ. (1979). K562 human leukaemic cells synthesize embryonic haemoglobin in response to haemin. Nature 280: 164-165.
26. Shapiro VS, Lee P, Winoto A. (1995). Identification and cloning of the G3B cDNA encoding a 3′ segment of a protein binding to GATA-3. Gene 163: 329-330.
27. Steele-Perkins G, Fang W, Yang XH, Van Gele M, Carling T, Gu J et al. (2001). Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily. Genes Dev 15: 2250-2262.
28. Takahashi N, Dong WF, Bainbridge M, Hull A, Pastural E, Pearson D et al. (2005). RIZ1 is down-regulated during CML progression and displays tumor suppressor properties in CML cell lines. Blood 106: 1028.
29. Tusher V, Tibshirani R, Chu C. (2001). Significance analysis of microarrays applied to ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121.
30. van de Loosdrecht AA, Beelen RH, Ossenkoppele GJ, Broekhoven MG, Langenhuijsen MM. (1994). A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia. J Immunol Methods 174: 311-320.
31. Woelfle J, Chia DJ, Rotwein P. (2003). Transcription Regulatory Regions Database (TRRD): its status in 2002. J Biol Chem 278: 51261-51266.
32. Woessmann W, Mivechi NF. (2001). Role of ERK activation in growth and erythroid differentiation of K562 cells. Exp Cell Res 264: 193-200.
33. Woessmann W, Zwanzger D, Borkhardt A. (2004). ERK signaling pathway is differentially involved in erythroid differentiation of K562 cells depending on time and the inducing agent. Cell Biol Int 28: 403-410.
34. Xie M, Shao G, Buyse IE, Huang S. (1997). Transcriptional repression mediated by the PR domain zinc finger gene RIZ. J Biol Chem 272: 26360-26366.