Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42995-43006

  Chittka, Alexandra ^a   Nitarska, Justyna ^b   Grazini, Ursula ^a   Richardson, William D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; ARGININE; CELL PROLIFERATION; CYTOLOGY; METHYLATION; NEURONS; PROTEINS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELL-CYCLE PROGRESSION; METHYLTRANSFERASES; MUTATIONAL ANALYSIS; NEURAL STEM CELL; NEURONAL DIFFERENTIATION; PROTEIN-ARGININE METHYLTRANSFERASE; REGULATORY COMPLEXES; REGULATORY DOMAIN;

STEM CELLS;

BUB1 RELATED PROTEIN; CYCLIN B; MESSENGER RNA; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PRDM4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN DEVELOPMENT; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE OVEREXPRESSION; HISTONE METHYLATION; IN VITRO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ZINC FINGER MOTIF;

EID: 84871133298     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.392746     Document Type: Article

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