MDS1/EVI1 enhances TGF-β1 signaling and strengthens its growth-inhibitory effect, but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-β1

Leukemia

Volumn 13, Issue 3, 1999, Pages 348-357

  Sood, R ^a   Talwar Trikha, A ^a   Chakrabarti, S R ^a   Nucifora, G ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

AML1; AML1 MDS1 EVI1; G CSF; MDS1 EVI1; t(3; 21); TGF 1

Indexed keywords

CANCER GROWTH FACTOR; DNA; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH INHIBITOR; HYBRID PROTEIN; INTERLEUKIN 3; ZINC FINGER PROTEIN;

ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL PROLIFERATION; CHROMOSOME 3; CHROMOSOME REARRANGEMENT; DNA BINDING; DNA FLANKING REGION; GENE FUSION; GENE MUTATION; GRANULOCYTE; GROWTH INHIBITION; HEMATOPOIETIC STEM CELL; HUMAN; LYMPHOCYTE TRANSFORMATION; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPRESSOR GENE; TRANSCRIPTION REGULATION; TRANSGENE; YEAST CELL;

EID: 0033014867     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401360     Document Type: Article

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