Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity

Aging Cell

Volumn 14, Issue 2, 2015, Pages 209-218

  Satoh, Akiko ^a   Brace, Cynthia S ^a   Rensing, Nick ^a   Imai, Shin Ichiro ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Age associated pathophysiology; Aging; DMH enriched gene; Dorsomedial hypothalamus; Nkx2 1; NREM delta power; Prdm13

Indexed keywords

COREPRESSOR PROTEIN; NEUROPEPTIDE; NEUROPEPTIDE VF PRECURSOR; NUCLEIC ACID BINDING PROTEIN; PR DOMAIN CONTAINING 13 PROTEIN; PROTEIN PRECURSOR; SK1 FAMILY TRANSCRIPTIONAL COREPRESSOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; UNCLASSIFIED DRUG; HISTONE LYSINE METHYLTRANSFERASE; PRDM13 PROTEIN, MOUSE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BODY COMPOSITION; BODY WEIGHT; BRAIN REGION; CIRCADIAN RHYTHM; CONTROLLED STUDY; DIET RESTRICTION; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; FEMALE; FOOD INTAKE; GENE EXPRESSION PROFILING; GENE SILENCING; HEK293 CELL LINE; HYPOTHALAMUS NUCLEUS; LIGHT DARK CYCLE; LONGEVITY; MOUSE; NERVE CELL; NONHUMAN; NONREM SLEEP; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REM SLEEP; SLEEP QUALITY; SLEEP WAKING CYCLE; TRANSCRIPTION INITIATION SITE; WAKEFULNESS; AGE; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; DEFICIENCY; ENERGY METABOLISM; GENETICS; HUMAN; HYPOTHALAMUS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROMOTER REGION; SLEEP;

MAMMALIA; MUS;

ADIPOSITY; AGE FACTORS; AMINO ACID SEQUENCE; ANIMALS; ENERGY METABOLISM; FEMALE; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; HYPOTHALAMUS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SLEEP; TRANSCRIPTION FACTORS;

EID: 84924266513     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12299     Document Type: Article

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