Glycolytic reprogramming in myofibroblast differentiation and lung fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 192, Issue 12, 2015, Pages 1462-1474

  Xie, Na ^a   Tan, Zheng ^a,b   Banerjee, Sami ^a   Cui, Huachun ^a   Ge, Jing ^a   Liu, Rui Ming ^a   Bernard, Karen ^a   Thannickal, Victor J ^a   Liu, Gang ^a  

^a University of Alabama at Birmingham   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Glycolysis; HIF 1 ; Lung fibrosis; Myofibroblast; PFKFB3

Indexed keywords

6 BIPHOSPHATASE 3; 6 PHOSPHOFRUCTO 2 KINASE; ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; FRUCTOSE 2; FRUCTOSE 2,6 BISPHOSPHATE; FRUCTOSE 6 PHOSPHATE; GLYCOLYTIC ENZYME; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTIC ACID; SUCCINIC ACID; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CITRIC ACID CYCLE; CONTROLLED STUDY; EXPERIMENTAL PULMONARY FIBROSIS; GLUCOSE INTAKE; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; LUNG PARENCHYMA; MITOCHONDRIAL RESPIRATION; MOUSE; MYOFIBROBLAST; NONHUMAN; NUCLEAR REPROGRAMMING; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; FIBROSING ALVEOLITIS; LUNG; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GLYCOLYSIS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; LUNG; MICE; MICE, INBRED C57BL; MYOFIBROBLASTS;

EID: 84952063696     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201504-0780OC     Document Type: Article

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