The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase

Cell Metabolism

Volumn 17, Issue 6, 2013, Pages 988-999

  Sciacovelli, Marco ^a   Guzzo, Giulia ^a   Morello, Virginia ^c   Frezza, Christian ^d   Zheng, Liang ^d,e   Nannini, Nazarena ^b   Calabrese, Fiorella ^b   Laudiero, Gabriella ^f   Esposito, Franca ^f   Landriscina, Matteo ^g   Defilippi, Paola ^c   Bernardi, Paolo ^a   Rasola, Andrea ^a  

^a VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^e UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^f UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^g UNIVERSITY OF FOGGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN TRAP1; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL TRANSFORMATION; COLORECTAL CANCER; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME STABILITY; FEMALE; GLYCOLYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; RESPIRATORY CHAIN;

CARCINOGENESIS; CELL LINE, TUMOR; CELL PROLIFERATION; HELA CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOCHONDRIA; NEOPLASMS; OXYGEN CONSUMPTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SUCCINATE DEHYDROGENASE;

EID: 84878813471     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.04.019     Document Type: Article

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