메뉴 건너뛰기




Volumn 19, Issue 1, 2014, Pages 37-48

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis

(24)  Schoors, Sandra a,b   De Bock, Katrien a,b   Cantelmo, Anna Rita a,b   Georgiadou, Maria a,b   Ghesquière, Bart a,b   Cauwenberghs, Sandra a,b   Kuchnio, Anna a,b   Wong, Brian W a,b   Quaegebeur, Annelies a,b   Goveia, Jermaine a,b   Bifari, Francesco a,b   Wang, Xingwu a,b   Blanco, Raquel c   Tembuyser, Bieke a,b   Cornelissen, Ivo a,b   Bouché, Ann a,b   Vinckier, Stefan a,b   Diaz Moralli, Santiago d   Gerhardt, Holger a,b,c   Telang, Sucheta e   more..


Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOFRUCTOKINASE 2 FRUCTOSE 2,6 BISPHOSPHATASE 3 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

EID: 84891841003     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.11.008     Document Type: Article
Times cited : (426)

References (37)
  • 8
    • 84887456534 scopus 로고    scopus 로고
    • Role of endothelial cell metabolism in vessel sprouting
    • K. De Bock, M. Georgiadou, and P. Carmeliet Role of endothelial cell metabolism in vessel sprouting Cell Metab. 18 2013 634 647
    • (2013) Cell Metab. , vol.18 , pp. 634-647
    • De Bock, K.1    Georgiadou, M.2    Carmeliet, P.3
  • 10
    • 79953244361 scopus 로고    scopus 로고
    • Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
    • J.M. Ebos, and R.S. Kerbel Antiangiogenic therapy: impact on invasion, disease progression, and metastasis Nat Rev Clin Oncol 8 2011 210 221
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 210-221
    • Ebos, J.M.1    Kerbel, R.S.2
  • 11
    • 0023193659 scopus 로고
    • Changes in the concentration of cAMP, fructose 2,6-bisphosphate and related metabolites and enzymes in Saccharomyces cerevisiae during growth on glucose
    • DOI 10.1111/j.1432-1033.1987.tb11067.x
    • J. François, P. Eraso, and C. Gancedo Changes in the concentration of cAMP, fructose 2,6-bisphosphate and related metabolites and enzymes in Saccharomyces cerevisiae during growth on glucose Eur. J. Biochem. 164 1987 369 373 (Pubitemid 17066662)
    • (1987) European Journal of Biochemistry , vol.164 , Issue.2 , pp. 369-373
    • Francois, J.1    Eraso, P.2    Gancedo, C.3
  • 12
    • 80054000495 scopus 로고    scopus 로고
    • Coordinating cell behaviour during blood vessel formation
    • I. Geudens, and H. Gerhardt Coordinating cell behaviour during blood vessel formation Development 138 2011 4569 4583
    • (2011) Development , vol.138 , pp. 4569-4583
    • Geudens, I.1    Gerhardt, H.2
  • 13
    • 84864402951 scopus 로고    scopus 로고
    • Anticancer agents that counteract tumor glycolysis
    • C. Granchi, and F. Minutolo Anticancer agents that counteract tumor glycolysis ChemMedChem 7 2012 1318 1350
    • (2012) ChemMedChem , vol.7 , pp. 1318-1350
    • Granchi, C.1    Minutolo, F.2
  • 14
    • 84867348672 scopus 로고    scopus 로고
    • Endothelial cell metabolism and implications for cancer therapy
    • U. Harjes, K. Bensaad, and A.L. Harris Endothelial cell metabolism and implications for cancer therapy Br. J. Cancer 107 2012 1207 1212
    • (2012) Br. J. Cancer , vol.107 , pp. 1207-1212
    • Harjes, U.1    Bensaad, K.2    Harris, A.L.3
  • 16
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • A. Herrero-Mendez, A. Almeida, E. Fernández, C. Maestre, S. Moncada, and J.P. Bolaños The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1 Nat. Cell Biol. 11 2009 747 752
    • (2009) Nat. Cell Biol. , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernández, E.3    Maestre, C.4    Moncada, S.5    Bolaños, J.P.6
  • 17
    • 77950364116 scopus 로고    scopus 로고
    • Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury
    • P. Hindryckx, A. Waeytens, D. Laukens, H. Peeters, J. Van Huysse, L. Ferdinande, P. Carmeliet, and M. De Vos Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury Lab. Invest. 90 2010 566 576
    • (2010) Lab. Invest. , vol.90 , pp. 566-576
    • Hindryckx, P.1    Waeytens, A.2    Laukens, D.3    Peeters, H.4    Van Huysse, J.5    Ferdinande, L.6    Carmeliet, P.7    De Vos, M.8
  • 21
  • 22
    • 80054046029 scopus 로고    scopus 로고
    • Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation
    • S.Y. Lunt, and M.G. Vander Heiden Aerobic glycolysis: meeting the metabolic requirements of cell proliferation Annu. Rev. Cell Dev. Biol. 27 2011 441 464
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27 , pp. 441-464
    • Lunt, S.Y.1    Vander Heiden, M.G.2
  • 23
    • 84872021668 scopus 로고    scopus 로고
    • Vascular endothelial growth factor a in intraocular vascular disease
    • J.W. Miller, J. Le Couter, E.C. Strauss, and N. Ferrara Vascular endothelial growth factor a in intraocular vascular disease Ophthalmology 120 2013 106 114
    • (2013) Ophthalmology , vol.120 , pp. 106-114
    • Miller, J.W.1    Le Couter, J.2    Strauss, E.C.3    Ferrara, N.4
  • 25
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • M. Potente, H. Gerhardt, and P. Carmeliet Basic and therapeutic aspects of angiogenesis Cell 146 2011 873 887
    • (2011) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 27
    • 84887150456 scopus 로고    scopus 로고
    • Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON: A Multicenter Cohort Study (SEVEN-UP)
    • SEVEN-UP Study Group
    • S. Rofagha, R.B. Bhisitkul, D.S. Boyer, S.R. Sadda, K. Zhang SEVEN-UP Study Group Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON: A Multicenter Cohort Study (SEVEN-UP) Ophthalmology 120 2013 2292 2299
    • (2013) Ophthalmology , vol.120 , pp. 2292-2299
    • Rofagha, S.1    Bhisitkul, R.B.2    Boyer, D.S.3    Sadda, S.R.4    Zhang, K.5
  • 28
    • 84155166961 scopus 로고    scopus 로고
    • Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices
    • A. Sacharidou, A.N. Stratman, and G.E. Davis Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices Cells Tissues Organs (Print) 195 2012 122 143
    • (2012) Cells Tissues Organs (Print) , vol.195 , pp. 122-143
    • Sacharidou, A.1    Stratman, A.N.2    Davis, G.E.3
  • 29
    • 77949459766 scopus 로고    scopus 로고
    • Oxygen-induced retinopathy: A model for vascular pathology in the retina
    • A. Scott, and M. Fruttiger Oxygen-induced retinopathy: a model for vascular pathology in the retina Eye (Lond.) 24 2010 416 421
    • (2010) Eye (Lond.) , vol.24 , pp. 416-421
    • Scott, A.1    Fruttiger, M.2
  • 30
    • 80052988662 scopus 로고    scopus 로고
    • Structure-based development of small molecule PFKFB3 inhibitors: A framework for potential cancer therapeutic agents targeting the Warburg effect
    • M. Seo, J.D. Kim, D. Neau, I. Sehgal, and Y.H. Lee Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect PLoS ONE 6 2011 e24179
    • (2011) PLoS ONE , vol.6 , pp. 24179
    • Seo, M.1    Kim, J.D.2    Neau, D.3    Sehgal, I.4    Lee, Y.H.5
  • 31
    • 84863691378 scopus 로고    scopus 로고
    • Modeling and predicting clinical efficacy for drugs targeting the tumor milieu
    • M. Singh, and N. Ferrara Modeling and predicting clinical efficacy for drugs targeting the tumor milieu Nat. Biotechnol. 30 2012 648 657
    • (2012) Nat. Biotechnol. , vol.30 , pp. 648-657
    • Singh, M.1    Ferrara, N.2
  • 32
    • 84855655264 scopus 로고    scopus 로고
    • The expanding role of vascular endothelial growth factor inhibitors in ophthalmology
    • M.W. Stewart The expanding role of vascular endothelial growth factor inhibitors in ophthalmology Mayo Clin. Proc. 87 2012 77 88
    • (2012) Mayo Clin. Proc. , vol.87 , pp. 77-88
    • Stewart, M.W.1
  • 35
    • 0020438908 scopus 로고
    • A kinetic study of pyrophosphate: Fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate
    • E. Van Schaftingen, B. Lederer, R. Bartrons, and H.G. Hers A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate Eur. J. Biochem. 129 1982 191 195
    • (1982) Eur. J. Biochem. , vol.129 , pp. 191-195
    • Van Schaftingen, E.1    Lederer, B.2    Bartrons, R.3    Hers, H.G.4
  • 36
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • T.A. Wynn, A. Chawla, and J.W. Pollard Macrophage biology in development, homeostasis and disease Nature 496 2013 445 455
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 37
    • 67349131613 scopus 로고    scopus 로고
    • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases in cancer
    • A. Yalcin, S. Telang, B. Clem, and J. Chesney Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer Exp. Mol. Pathol. 86 2009 174 179
    • (2009) Exp. Mol. Pathol. , vol.86 , pp. 174-179
    • Yalcin, A.1    Telang, S.2    Clem, B.3    Chesney, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.