The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments

Journal of Biological Chemistry

Volumn 290, Issue 49, 2015, Pages 29217-29230

  Vajjhala, Parimala R ^a   Lu, Alvin ^b   Brown, Darren L ^a   Pang, Siew Wai ^a   Sagulenko, Vitaliya ^a   Sester, David P ^a   Cridland, Simon O ^a   Hill, Justine M ^a   Schroder, Kate ^a   Stow, Jennifer L ^a   Wu, Hao ^b   Stacey, Katryn J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CHEMICAL ACTIVATION;

ADAPTOR PROTEINS; CATALYTIC DOMAINS; CELLULAR STRESS; DEATH-RECEPTOR; EFFECTOR DOMAINS; FOLD SUPERFAMILIES; INTERACTION MODES; SELF-ASSOCIATIONS;

ASSOCIATION REACTIONS;

ADAPTOR PROTEIN; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CARD PROTEIN; PROCASPASE 8; UNCLASSIFIED DRUG; CASP8 PROTEIN, HUMAN; CASPASE 8; CYTOSKELETON PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN BINDING; PYCARD PROTEIN, HUMAN;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY; APOPTOSIS; CELL DEATH; ENZYME ACTIVE SITE; FLUORESCENCE MICROSCOPY; HEK293 CELL LINE; HUMAN; INFLAMMATION; METABOLISM; MUTATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASE 1; CASPASE 8; CATALYTIC DOMAIN; CELL DEATH; CYTOSKELETAL PROTEINS; HEK293 CELLS; HUMANS; INFLAMMASOMES; INFLAMMATION; MICROSCOPY, FLUORESCENCE; MUTATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

EID: 84951814419     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.687731     Document Type: Article

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