Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2

Cell Discovery

Volumn 1, Issue , 2015, Pages

  Lu, Alvin ^a,b   Li, Yang ^a,b   Yin, Qian ^a,b   Ruan, Jianbin ^a,b   Yu, Xiong ^c   Egelman, Edward ^c   Wu, Hao ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

AIM2 PYD filament; ASC dependent inflammasome; Cryo EM; Death Domain interaction; Helical reconstruction; Inflammasome; Nucleated polymerization; Plasticity

Indexed keywords

ABSENT IN MELANOMA 2 PROTEIN; GREEN FLUORESCENT PROTEIN; INFLAMMASOME; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CASPASE ACTIVATION AND RECRUITMENT DOMAIN; CELL MATURATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON TOMOGRAPHY; ESCHERICHIA COLI; NONHUMAN; PLASTICITY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN INTERACTION; PYRIN DOMAIN; PYROPTOSIS;

EID: 84951838786     PISSN: None     EISSN: 20565968     Source Type: Journal    
DOI: 10.1038/celldisc.2015.13     Document Type: Article

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