Differential affinity of FLIP and procaspase 8 for FADD's DED binding surfaces regulates DISC assembly

Nature Communications

Volumn 5, Issue , 2014, Pages

  Majkut, J ^a   Sgobba, M ^a,b   Holohan, C ^a   Crawford, N ^a   Logan, A E ^a   Kerr, E ^a   Higgins, C A ^a   Redmond, K L ^a   Riley, J S ^a   Stasik, I ^a   Fennell, D A ^a,c   Van Schaeybroeck, S ^a   Haider, S ^a,d   Johnston, P G ^a   Haigh, D ^a   Longley, D B ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLICE INHIBITORY PROTEIN; PROCASPASE 8; TRIPARTITE MOTIF PROTEIN 5; CASPASE 8; FADD PROTEIN, HUMAN; PROTEIN BINDING;

CELL ORGANELLE; GENE EXPRESSION; INHIBITOR; SIGNAL;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL MUTANT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEATH EFFECTOR DOMAIN; ENZYME MECHANISM; ENZYME REGULATION; HUMAN; HUMAN CELL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; STOICHIOMETRY; HCT116 CELL LINE; IMMUNOPRECIPITATION; METABOLISM; SIZE EXCLUSION CHROMATOGRAPHY; WESTERN BLOTTING;

BLOTTING, WESTERN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CHROMATOGRAPHY, GEL; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HCT116 CELLS; HUMANS; IMMUNOPRECIPITATION; PROTEIN BINDING;

EID: 84896890429     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4350     Document Type: Article

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