The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

Nature Structural and Molecular Biology

Volumn 17, Issue 11, 2010, Pages 1324-1329

  Wang, Liwei ^a,h,i   Yang, Jin Kuk ^a,b   Kabaleeswaran, Venkataraman ^a   Rice, Amanda J ^c   Cruz, Anthony C ^d   Park, Ah Young ^e   Yin, Qian ^a   Damko, Ermelinda ^a   Jang, Se Bok ^a,f   Raunser, Stefan ^c,h   Robinson, Carol V ^e   Siegel, Richard M ^d   Walz, Thomas ^c,g   Wu, Hao ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Soongsil University   (South Korea)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f Pusan National University   (South Korea)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h INSTITUTE OF BIOPHYSICS   (China)

ⁱ MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; DEATH INDUCING SIGNAL COMPLEX; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; OLIGOMER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; COMPLEX FORMATION; CORRELATION COEFFICIENT; CRYSTAL STRUCTURE; GENE DISRUPTION; GENE MUTATION; HUMAN; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD95; APOPTOSIS; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; CASPASE 8; CELL LINE; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 78549236456     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.1920     Document Type: Article

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