Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions

Journal of Molecular Biology

Volumn 426, Issue 7, 2014, Pages 1420-1427

  Lu, Alvin ^a   Kabaleeswaran, Venkataraman ^a   Fu, Tianmin ^a   Magupalli, Venkat Giri ^a   Wu, Hao ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

AIM2; DED; inflammasome; interaction; PYD

Indexed keywords

DOUBLE STRANDED DNA; MALTOSE BINDING PROTEIN; PROTEIN ABSENT IN MELANOMA 2; UNCLASSIFIED DRUG; ABSENT IN MELANOMA 2 LIKE RECEPTOR; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING CARD; CASPASE 8; CYTOKINE; DEATH EFFECTOR DOMAIN PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PYRIN DOMAIN PROTEIN;

ARTICLE; CRYSTAL STRUCTURE; DNA STRUCTURE; MELANOMA; MUTAGENESIS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SEQUENCE HOMOLOGY; ANIMAL CELL; CELL DEATH; HUMAN; HUMAN CELL; IN VITRO STUDY; INNATE IMMUNITY; MOLECULAR INTERACTION; MOLECULAR SENSOR; MOLECULE; MOUSE; MUTANT; NONHUMAN; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SPECIES COMPARISON; STRUCTURAL HOMOLOGY;

AIM2; DED; INFLAMMASOME; INTERACTION; PYD;

HUMANS; INFLAMMASOMES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 84895923768     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.12.029     Document Type: Article

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