Network analysis of gene essentiality in functional genomics experiments

Genome Biology

Volumn 16, Issue 1, 2015, Pages

  Jiang, Peng ^a   Wang, Hongfang ^b   Li, Wei ^a   Zang, Chongzhi ^a   Li, Bo ^a   Wong, Yinling J ^b   Meyer, Cliff ^a   Liu, Jun S ^c   Aster, Jon C ^b   Liu, X Shirley ^a,d  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d TONGJI UNIVERSITY   (China)

Author keywords

CRISPR screen; Gene essentiality; Network analysis

Indexed keywords

SHORT HAIRPIN RNA;

ARTICLE; CANCER PATIENT; CANCER SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; FUNCTIONAL GENOMICS; GENE ESSENTIALITY; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC PARAMETERS; HUMAN; HUMAN CELL; INFORMATION PROCESSING; NETWORK ESSENTIALITY SCORING TOOL; ONCOGENE; PREDICTION; QUALITY CONTROL; SURVIVAL RATE; CELL LINE; CRISPR CAS SYSTEM; ESSENTIAL GENE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; GENOMICS; MORTALITY; NEOPLASM; PROCEDURES; SOFTWARE; SURVIVAL ANALYSIS;

CELL LINE; CRISPR-CAS SYSTEMS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENES, ESSENTIAL; GENOMICS; HUMANS; NEOPLASMS; SOFTWARE; SURVIVAL ANALYSIS;

EID: 84945567414     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0808-9     Document Type: Article

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