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Volumn 34, Issue 14, 2014, Pages 5023-5028

Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons

Author keywords

Amyloid ; Extrasynaptic; Nitric oxide; NMDA receptor; Synaptic

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; DYNAMIN RELATED PROTEIN 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG;

EID: 84899412672     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2907-13.2014     Document Type: Article
Times cited : (50)

References (38)
  • 1
    • 70549106846 scopus 로고    scopus 로고
    • Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
    • CrossRef Medline
    • Abramov E, Dolev I, Fogel H, Ciccotosto GD, Ruff E, Slutsky I (2009) Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci 12:1567-1576. CrossRef Medline
    • (2009) Nat Neurosci , vol.12 , pp. 1567-1576
    • Abramov, E.1    Dolev, I.2    Fogel, H.3    Ciccotosto, G.D.4    Ruff, E.5    Slutsky, I.6
  • 2
    • 50249135503 scopus 로고    scopus 로고
    • Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
    • CrossRef Medline
    • Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 31:454-463. CrossRef Medline
    • (2008) Trends Neurosci , vol.31 , pp. 454-463
    • Bezprozvanny, I.1    Mattson, M.P.2
  • 3
    • 78649417803 scopus 로고    scopus 로고
    • Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-β production
    • CrossRef Medline
    • Bordji K, Becerril-Ortega J, Nicole O, Buisson A (2010) Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-β production. J Neurosci 30:15927-15942. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 15927-15942
    • Bordji, K.1    Becerril-Ortega, J.2    Nicole, O.3    Buisson, A.4
  • 4
    • 0035194145 scopus 로고    scopus 로고
    • Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid β-peptide
    • CrossRef Medline
    • Butterfield DA, Drake J, Pocernich C, Castegna A (2001) Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide. Trends Mol Med 7:548-554. CrossRef Medline
    • (2001) Trends Mol Med , vol.7 , pp. 548-554
    • Butterfield, D.A.1    Drake, J.2    Pocernich, C.3    Castegna, A.4
  • 5
    • 64249133725 scopus 로고    scopus 로고
    • S-Nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury
    • CrossRef Medline
    • Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA (2009) S-Nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury. Science 324:102-105. CrossRef Medline
    • (2009) Science , vol.324 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3    Cieplak, P.4    Godzik, A.5    Gu, Z.6    Lipton, S.A.7
  • 6
    • 0033995950 scopus 로고    scopus 로고
    • Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation
    • CrossRef Medline
    • Choi YB, Tenneti L, Le DA, Ortiz J, Bai G, Chen HS, Lipton SA (2000) Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation. Nat Neurosci 3:15-21. CrossRef Medline
    • (2000) Nat Neurosci , vol.3 , pp. 15-21
    • Choi, Y.B.1    Tenneti, L.2    Le, D.A.3    Ortiz, J.4    Bai, G.5    Chen, H.S.6    Lipton, S.A.7
  • 7
    • 0033600913 scopus 로고    scopus 로고
    • PSD-95 assembles a ternary complex with the N-methyl-d-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain
    • CrossRef Medline
    • Christopherson KS, Hillier BJ, Lim WA, Bredt DS (1999) PSD-95 assembles a ternary complex with the N-methyl-d-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J Biol Chem 274:27467-27473. CrossRef Medline
    • (1999) J Biol Chem , vol.274 , pp. 27467-27473
    • Christopherson, K.S.1    Hillier, B.J.2    Lim, W.A.3    Bredt, D.S.4
  • 10
    • 0033637918 scopus 로고    scopus 로고
    • Nitric oxide synthase: Models and mechanisms
    • CrossRef Medline
    • Groves JT, Wang CC (2000) Nitric oxide synthase: models and mechanisms. Curr Opin Chem Biol 4:687-695. CrossRef Medline
    • (2000) Curr Opin Chem Biol , vol.4 , pp. 687-695
    • Groves, J.T.1    Wang, C.C.2
  • 11
    • 77956917231 scopus 로고    scopus 로고
    • Synaptic versus extrasynaptic NMDA receptor signalling: Implications for neurodegenerative disorders
    • CrossRef Medline
    • Hardingham GE, Bading H (2010) Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 11:682-696. CrossRef Medline
    • (2010) Nat Rev Neurosci , vol.11 , pp. 682-696
    • Hardingham, G.E.1    Bading, H.2
  • 12
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • CrossRef Medline
    • Hardingham GE, Fukunaga Y, Bading H (2002) Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 5:405-414. CrossRef Medline
    • (2002) Nat Neurosci , vol.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, Y.2    Bading, H.3
  • 15
    • 33645837486 scopus 로고    scopus 로고
    • Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons
    • CrossRef Medline
    • Ivanov A, Pellegrino C, Rama S, Dumalska I, Salyha Y, Ben-Ari Y, Medina I (2006) Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons. J Physiol 572:789-798. CrossRef Medline
    • (2006) J Physiol , vol.572 , pp. 789-798
    • Ivanov, A.1    Pellegrino, C.2    Rama, S.3    Dumalska, I.4    Salyha, Y.5    Ben-Ari, Y.6    Medina, I.7
  • 16
  • 19
    • 77955570062 scopus 로고    scopus 로고
    • Glutamate receptors, neurotoxicity and neurodegeneration
    • CrossRef Medline
    • Lau A, Tymianski M (2010) Glutamate receptors, neurotoxicity and neurodegeneration. Pflügers Archiv 460:525-542. CrossRef Medline
    • (2010) Pflügers Archiv , vol.460 , pp. 525-542
    • Lau, A.1    Tymianski, M.2
  • 20
    • 79955769953 scopus 로고    scopus 로고
    • Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
    • CrossRef Medline
    • Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar G, Selkoe DJ (2011) Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. J Neurosci 31:6627-6638. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 6627-6638
    • Li, S.1    Jin, M.2    Koeglsperger, T.3    Shepardson, N.E.4    Shankar, G.5    Selkoe, D.J.6
  • 21
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
    • CrossRef Medline
    • Lipton SA (2006) Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat Rev Drug Discov 5:160-170. CrossRef Medline
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 22
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitrosocompounds
    • CrossRef Medline
    • Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS (1993) A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitrosocompounds. Nature 364:626-632. CrossRef Medline
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Choi, Y.B.2    Pan, Z.H.3    Lei, S.Z.4    Chen, H.S.5    Sucher, N.J.6    Loscalzo, J.7    Singel, D.J.8    Stamler, J.S.9
  • 25
    • 84878443676 scopus 로고    scopus 로고
    • Aberrant protein S-nitrosylation in neurodegenerative diseases
    • CrossRef Medline
    • Nakamura T, Tu S, Akhtar MW, Sunico CR, Okamoto S, Lipton SA (2013) Aberrant protein S-nitrosylation in neurodegenerative diseases. Neuron 78:596-614. CrossRef Medline
    • (2013) Neuron , vol.78 , pp. 596-614
    • Nakamura, T.1    Tu, S.2    Akhtar, M.W.3    Sunico, C.R.4    Okamoto, S.5    Lipton, S.A.6
  • 27
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-β-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
    • CrossRef Medline
    • Palop JJ, Mucke L (2010) Amyloid-β-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 13:812-818. CrossRef Medline
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 29
    • 0032892343 scopus 로고    scopus 로고
    • Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist-a review of preclinical data
    • CrossRef Medline
    • Parsons CG, Danysz W, Quack G (1999) Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist-a review of preclinical data. Neuropharmacology 38:735-767. CrossRef Medline
    • (1999) Neuropharmacology , vol.38 , pp. 735-767
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 31
    • 80052150240 scopus 로고    scopus 로고
    • S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide
    • CrossRef Medline
    • Qu J, Nakamura T, Cao G, Holland EA, McKercher SR, Lipton SA (2011) S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide. Proc Natl Acad SciU S A 108:14330-14335. CrossRef Medline
    • (2011) Proc Natl Acad SciU S A , vol.108 , pp. 14330-14335
    • Qu, J.1    Nakamura, T.2    Cao, G.3    Holland, E.A.4    McKercher, S.R.5    Lipton, S.A.6
  • 32
    • 34248181511 scopus 로고    scopus 로고
    • Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
    • CrossRef Medline
    • Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L (2007) Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model. Science 316: 750-754. CrossRef Medline
    • (2007) Science , vol.316 , pp. 750-754
    • Roberson, E.D.1    Scearce-Levie, K.2    Palop, J.J.3    Yan, F.4    Cheng, I.H.5    Wu, T.6    Gerstein, H.7    Yu, G.Q.8    Mucke, L.9
  • 33
    • 0033546347 scopus 로고    scopus 로고
    • Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
    • CrossRef Medline
    • Sattler R, Xiong Z, Lu WY, Hafner M, MacDonald JF, Tymianski M (1999) Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 284:1845-1848. CrossRef Medline
    • (1999) Science , vol.284 , pp. 1845-1848
    • Sattler, R.1    Xiong, Z.2    Lu, W.Y.3    Hafner, M.4    Macdonald, J.F.5    Tymianski, M.6
  • 34
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • CrossRef Medline
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298:789-791. CrossRef Medline
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 35
    • 80053254091 scopus 로고    scopus 로고
    • Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection
    • CrossRef Medline
    • Stark DT, Bazan NG (2011) Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection. J Neurosci 31:13710-13721. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 13710-13721
    • Stark, D.T.1    Bazan, N.G.2
  • 38
    • 84860689529 scopus 로고    scopus 로고
    • Synaptic NMDA receptors mediate hypoxic excitotoxic death
    • CrossRef Medline
    • Wroge CM, Hogins J, Eisenman L, Mennerick S (2012) Synaptic NMDA receptors mediate hypoxic excitotoxic death. J Neurosci 32:6732-6742. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 6732-6742
    • Wroge, C.M.1    Hogins, J.2    Eisenman, L.3    Mennerick, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.