Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 19, 2014, Pages 6964-6969

  Padera, Irina ^a   Sengupta, Rajib ^a   Cebula, Marcus ^a   Xu, Jianqiang ^a   Lundberg, Jon O ^a   Holmgren, Arne ^a   Johansson, Katarina ^a   Arnér, Elias S J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Nitric oxide; Oxidative stress; Redox regulation; Sulfur metabolism

Indexed keywords

CASPASE 3; CATHEPSIN B; CYSTINE; HYDROGEN PEROXIDE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; S DENITROSYLASE; S NITROSOTHIOL; THIOREDOXIN; THIOREDOXIN 1; THIOREDOXIN REDUCTASE 1; THIOREDOXIN RELATED PROTEIN OF 14 KDA; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MUTAGENESIS; NITROSYLATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PURIFICATION;

NITRIC OXIDE; OXIDATIVE STRESS; REDOX REGULATION; SULFUR METABOLISM;

CARCINOMA, SQUAMOUS CELL; CYSTEINE; CYSTINE; ENZYME ACTIVATION; GLUTATHIONE; HEK293 CELLS; HT29 CELLS; HUMANS; HYDROGEN PEROXIDE; LUNG NEOPLASMS; NADH, NADPH OXIDOREDUCTASES; NADP; NITRIC OXIDE; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SUBSTRATE SPECIFICITY; SULFUR; THIOREDOXIN REDUCTASE 1; THIOREDOXINS;

EID: 84900498924     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1317320111     Document Type: Article

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