메뉴 건너뛰기




Volumn 74, Issue , 2016, Pages 42-63

A review of toxicity studies of single-walled carbon nanotubes in laboratory animals

Author keywords

Carbon nanotubes; Inflammation; Inhalation; Intratracheal instillation; Nanomaterials; Nanotoxicology; Oxidative stress; Pharyngeal aspiration; Pulmonary toxicology; Single walled carbon nanotubes

Indexed keywords

SINGLE WALLED NANOTUBE; CARBON NANOTUBE;

EID: 84949871261     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2015.11.015     Document Type: Article
Times cited : (105)

References (115)
  • 1
    • 84880963815 scopus 로고    scopus 로고
    • Carbon nanotube structures and compositions: implications for toxicological studies
    • Informa Healthcare USA, New York, N.A. Monteiro-Riviere, C.L. Tran (Eds.)
    • Alexander A.J. Carbon nanotube structures and compositions: implications for toxicological studies. Nanotoxicology: Characterization, Dosing and Health Effects 2007, 7-18. Informa Healthcare USA, New York. N.A. Monteiro-Riviere, C.L. Tran (Eds.).
    • (2007) Nanotoxicology: Characterization, Dosing and Health Effects , pp. 7-18
    • Alexander, A.J.1
  • 3
    • 84899492527 scopus 로고    scopus 로고
    • Physicochemical characteristics of nanomaterials that affect pulmonary inflammation
    • Braakhuis H.M., Park M.V.D.Z., Gosens I., De Jong W., Cassee F. Physicochemical characteristics of nanomaterials that affect pulmonary inflammation. Part. Fibre Toxicol. 2014, 11:18. 10.1186/1743-8977-11-18.
    • (2014) Part. Fibre Toxicol. , vol.11 , pp. 18
    • Braakhuis, H.M.1    Park, M.V.D.Z.2    Gosens, I.3    De Jong, W.4    Cassee, F.5
  • 5
    • 84875307441 scopus 로고    scopus 로고
    • Response to pulmonary exposure to carbon nanotubes
    • Cambridge University Press, Cambridge, K. Donaldson, C. Poland, R. Duffin, J. Bonner (Eds.)
    • Castranova V., Mercer R.R. Response to pulmonary exposure to carbon nanotubes. The Toxicology of Carbon Nanotubes 2012, 134-149. Cambridge University Press, Cambridge. K. Donaldson, C. Poland, R. Duffin, J. Bonner (Eds.).
    • (2012) The Toxicology of Carbon Nanotubes , pp. 134-149
    • Castranova, V.1    Mercer, R.R.2
  • 6
    • 84875316354 scopus 로고    scopus 로고
    • Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers
    • Castranova V., Schulte P.A., Zumwalde R.D. Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers. Accou. Chem. Res. 2013, 46:642-649.
    • (2013) Accou. Chem. Res. , vol.46 , pp. 642-649
    • Castranova, V.1    Schulte, P.A.2    Zumwalde, R.D.3
  • 7
    • 84871869249 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition contributes to SWCNT-induced pulmonary fibrosis
    • Chang C.C., Tsai M.L.T., Huang H.C., Chen C.Y., Dai S.X. Epithelial-mesenchymal transition contributes to SWCNT-induced pulmonary fibrosis. Nanotoxicology 2012, 6:600-610.
    • (2012) Nanotoxicology , vol.6 , pp. 600-610
    • Chang, C.C.1    Tsai, M.L.T.2    Huang, H.C.3    Chen, C.Y.4    Dai, S.X.5
  • 10
    • 33645803825 scopus 로고    scopus 로고
    • Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure
    • Costa D.L., Lehmann J.R., Winsett D., Richards J., Ledbetter A.D., Dreher K.L. Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure. Toxicol. Sci. 2006, 91:237-246.
    • (2006) Toxicol. Sci. , vol.91 , pp. 237-246
    • Costa, D.L.1    Lehmann, J.R.2    Winsett, D.3    Richards, J.4    Ledbetter, A.D.5    Dreher, K.L.6
  • 11
    • 84887108887 scopus 로고    scopus 로고
    • Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes
    • Di Y.P., Tkach A.V., Yanamala N., Stanley S., Gao S., Shurin M.R., Kisin E.R., Kagan V.E., Shvedova A. Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes. Am. J. Respir. Cell Mol. Biol. 2013, 49:759-767.
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.49 , pp. 759-767
    • Di, Y.P.1    Tkach, A.V.2    Yanamala, N.3    Stanley, S.4    Gao, S.5    Shurin, M.R.6    Kisin, E.R.7    Kagan, V.E.8    Shvedova, A.9
  • 12
    • 0035226686 scopus 로고    scopus 로고
    • Effect of varying dietary fat levels on rat growth and oxidative DNA damage
    • Djuric Z., Lewis S.M., Lu M.H., Mayhugh M.H., Tang N., Hart R.W. Effect of varying dietary fat levels on rat growth and oxidative DNA damage. Nutr. Cancer 2001, 39:214-219.
    • (2001) Nutr. Cancer , vol.39 , pp. 214-219
    • Djuric, Z.1    Lewis, S.M.2    Lu, M.H.3    Mayhugh, M.H.4    Tang, N.5    Hart, R.W.6
  • 13
    • 84880958977 scopus 로고    scopus 로고
    • Nanotoxicity: challenging the myth of nano-specific toxicity
    • Donaldson K., Poland C.A. Nanotoxicity: challenging the myth of nano-specific toxicity. Curr. Opin. Biotechnol. 2013, 24:724-734.
    • (2013) Curr. Opin. Biotechnol. , vol.24 , pp. 724-734
    • Donaldson, K.1    Poland, C.A.2
  • 14
    • 33745597580 scopus 로고    scopus 로고
    • Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety
    • Donaldson K., Aiken R., Tran L., Stone V., Duffin R., Forrest G., Alexander A. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol. Sci. 2006, 92:5-22.
    • (2006) Toxicol. Sci. , vol.92 , pp. 5-22
    • Donaldson, K.1    Aiken, R.2    Tran, L.3    Stone, V.4    Duffin, R.5    Forrest, G.6    Alexander, A.7
  • 15
    • 77952317021 scopus 로고    scopus 로고
    • Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of lung fibre retention in the parietal pleura, inflammation and mesothelioma
    • Donaldson K., Murphy F.A., Duffin R., Poland C. Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of lung fibre retention in the parietal pleura, inflammation and mesothelioma. Part. Fibre Toxicol. 2010, 7:5. 10.1186/1743-8977-7-5.
    • (2010) Part. Fibre Toxicol. , vol.7 , pp. 5
    • Donaldson, K.1    Murphy, F.A.2    Duffin, R.3    Poland, C.4
  • 16
    • 0034107229 scopus 로고    scopus 로고
    • Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations
    • Driscoll K.E., Costa D.L., Hatch G., Henderson R., Oberdörster G., Salem H., Schlesinger R.B. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. Toxicol. Sci. 2000, 55:24-35.
    • (2000) Toxicol. Sci. , vol.55 , pp. 24-35
    • Driscoll, K.E.1    Costa, D.L.2    Hatch, G.3    Henderson, R.4    Oberdörster, G.5    Salem, H.6    Schlesinger, R.B.7
  • 17
    • 27944503449 scopus 로고    scopus 로고
    • Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology
    • Elder A., Gelein R., Finkelstein J.N., Driscoll K.E., Harkema J., Oberdörster G. Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology. Toxicol. Sci. 2005, 88:614-629.
    • (2005) Toxicol. Sci. , vol.88 , pp. 614-629
    • Elder, A.1    Gelein, R.2    Finkelstein, J.N.3    Driscoll, K.E.4    Harkema, J.5    Oberdörster, G.6
  • 18
    • 80855139735 scopus 로고    scopus 로고
    • Evaluation of dermal and eye irritation and skin sensitization due to carbon nanotubes
    • Ema M., Matsuda A., Kobayashi N., Naya M., Nakanishi J. Evaluation of dermal and eye irritation and skin sensitization due to carbon nanotubes. Regul. Toxicol. Pharmacol. 2011, 61:276-281.
    • (2011) Regul. Toxicol. Pharmacol. , vol.61 , pp. 276-281
    • Ema, M.1    Matsuda, A.2    Kobayashi, N.3    Naya, M.4    Nakanishi, J.5
  • 19
    • 84880702786 scopus 로고    scopus 로고
    • Genotoxicity evaluation for single-walled carbon nanotubes in battery on in vitro and in vivo assays
    • Ema M., Imamura T., Suzuki H., Kobayashi N., Naya M., Nakanishi J. Genotoxicity evaluation for single-walled carbon nanotubes in battery on in vitro and in vivo assays. J. Appl. Toxicol. 2013, 33:933-939.
    • (2013) J. Appl. Toxicol. , vol.33 , pp. 933-939
    • Ema, M.1    Imamura, T.2    Suzuki, H.3    Kobayashi, N.4    Naya, M.5    Nakanishi, J.6
  • 20
    • 84960425843 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity of carbon-based nanomaterials: a literature review
    • Ema M., Hougaard K.S., Kishimoto A., Honda K. Reproductive and developmental toxicity of carbon-based nanomaterials: a literature review. Nanotoxicology 2015, 10.3109/1435390.2015.1073811.
    • (2015) Nanotoxicology
    • Ema, M.1    Hougaard, K.S.2    Kishimoto, A.3    Honda, K.4
  • 21
    • 0003510680 scopus 로고    scopus 로고
    • Available at:, (accessed 08.06.15)
    • ENRHES (Engineered Nanoparticles: Review of Health and Environmental Safety) European Commission 2009, Available at:, (accessed 08.06.15). http://www.ecoweb.info/2775_3661_engineered-nanoparticles-review-health-environmental-safety.
    • (2009) European Commission
  • 24
    • 77954694221 scopus 로고    scopus 로고
    • Long-term follow-up of lung biodistribution and effect of instilled SWCNTs using multiscale imaging techniques
    • Faraj A.A., Besaad A., Cieslar K., Lacroix G., Canet-Soulas E., Crémillieux Y. Long-term follow-up of lung biodistribution and effect of instilled SWCNTs using multiscale imaging techniques. Nanotechnology 2010, 21(17):175103. 10.1088/0957-4484/21/17/175103.
    • (2010) Nanotechnology , vol.21 , Issue.17 , pp. 175103
    • Faraj, A.A.1    Besaad, A.2    Cieslar, K.3    Lacroix, G.4    Canet-Soulas, E.5    Crémillieux, Y.6
  • 27
    • 84929670850 scopus 로고    scopus 로고
    • Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression
    • Fujita K., Fukuda M., Fukui H., Horie M., Endoh S., Uchida K., Shichiri M., Morimoto Y., Iwahashi H. Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression. Nanotoxicology 2015, 9:290-301.
    • (2015) Nanotoxicology , vol.9 , pp. 290-301
    • Fujita, K.1    Fukuda, M.2    Fukui, H.3    Horie, M.4    Endoh, S.5    Uchida, K.6    Shichiri, M.7    Morimoto, Y.8    Iwahashi, H.9
  • 29
    • 84863804355 scopus 로고    scopus 로고
    • Acute pulmonary and moderate cardiovascular responses of spontaneous hypertensive rats after exposure to single-walled carbon nanotubes
    • Ge C., Meng L., Xu L., Bai R., Du J., Zhang L., Li Y., Chang Y., Zkao Y., Chen C. Acute pulmonary and moderate cardiovascular responses of spontaneous hypertensive rats after exposure to single-walled carbon nanotubes. Nanotoxicology 2012, 6:526-542.
    • (2012) Nanotoxicology , vol.6 , pp. 526-542
    • Ge, C.1    Meng, L.2    Xu, L.3    Bai, R.4    Du, J.5    Zhang, L.6    Li, Y.7    Chang, Y.8    Zkao, Y.9    Chen, C.10
  • 30
    • 84871922476 scopus 로고    scopus 로고
    • Redox control of teratogenesis
    • Hansen J.M., Harris C. Redox control of teratogenesis. Reprod. Toxicol. 2012, 35:165-179.
    • (2012) Reprod. Toxicol. , vol.35 , pp. 165-179
    • Hansen, J.M.1    Harris, C.2
  • 31
    • 84888129490 scopus 로고    scopus 로고
    • The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development
    • Huang X., Zhang F., Sun X., Choi K.Y., Niu G., Zhang G., Guo J., Lee S., Chen X. The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development. Biomaterials 2014, 35:856-865.
    • (2014) Biomaterials , vol.35 , pp. 856-865
    • Huang, X.1    Zhang, F.2    Sun, X.3    Choi, K.Y.4    Niu, G.5    Zhang, G.6    Guo, J.7    Lee, S.8    Chen, X.9
  • 32
    • 0033983168 scopus 로고    scopus 로고
    • Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study
    • Hubbard R., Venn A., Lewis S., Britton J. Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study. Am. J. Respir. Crit. Care Med. 2000, 161:5-8.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 5-8
    • Hubbard, R.1    Venn, A.2    Lewis, S.3    Britton, J.4
  • 34
    • 85013823158 scopus 로고    scopus 로고
    • Workplace inhalation exposure to engineered nanomaterials. Detection, measurement, and assessment
    • CRC Press, Boca Raton, N.A. Monteiro-Riviere, C.L. Tran (Eds.)
    • Jiménez A.S., Brouwer D., Van Tongeren M. Workplace inhalation exposure to engineered nanomaterials. Detection, measurement, and assessment. Nanotoxicology: Progress Toward Nanomedicine 2014, 77-96. CRC Press, Boca Raton. second ed. N.A. Monteiro-Riviere, C.L. Tran (Eds.).
    • (2014) Nanotoxicology: Progress Toward Nanomedicine , pp. 77-96
    • Jiménez, A.S.1    Brouwer, D.2    Van Tongeren, M.3
  • 35
    • 77952829224 scopus 로고    scopus 로고
    • A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics
    • Johnston H.J., Hutchison G.R., Christensen F.M., Peters S., Hankin S., Aschberger K., Stone V. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics. Nanotoxicology 2010, 4:207-246.
    • (2010) Nanotoxicology , vol.4 , pp. 207-246
    • Johnston, H.J.1    Hutchison, G.R.2    Christensen, F.M.3    Peters, S.4    Hankin, S.5    Aschberger, K.6    Stone, V.7
  • 38
    • 0036110825 scopus 로고    scopus 로고
    • Mechanisms for ovarian cycle disruption by immune/inflammatory stress
    • Karsch F., Battaglia D.F., Breen K.M., Debus N., Harris T.G. Mechanisms for ovarian cycle disruption by immune/inflammatory stress. Stress 2002, 5:101-112.
    • (2002) Stress , vol.5 , pp. 101-112
    • Karsch, F.1    Battaglia, D.F.2    Breen, K.M.3    Debus, N.4    Harris, T.G.5
  • 40
    • 80155146877 scopus 로고    scopus 로고
    • Pulmonary and systemic responses of highly pure and well-dispersed carbon nanotubes after intratracheal instillation
    • Kobayashi N., Naya M., Mizuno K., Yamamoto K., Ema M., Nakanishi J. Pulmonary and systemic responses of highly pure and well-dispersed carbon nanotubes after intratracheal instillation. Inhal. Toxicol. 2011, 23:814-828.
    • (2011) Inhal. Toxicol. , vol.23 , pp. 814-828
    • Kobayashi, N.1    Naya, M.2    Mizuno, K.3    Yamamoto, K.4    Ema, M.5    Nakanishi, J.6
  • 41
    • 77950154641 scopus 로고    scopus 로고
    • In vivo behavior of large doses of ultrashort and full-length single-walled carbon nanotubes after oral and intraperitoneal administration to Swiss mice
    • Kolosnjaj-Tabi J., Hartman K.B., Boudjemaa S., Ananta J.S., Morgant G., Szwarc H., Wilson L.J., Moussa F. In vivo behavior of large doses of ultrashort and full-length single-walled carbon nanotubes after oral and intraperitoneal administration to Swiss mice. ACS Nano 2010, 4:1481-1492.
    • (2010) ACS Nano , vol.4 , pp. 1481-1492
    • Kolosnjaj-Tabi, J.1    Hartman, K.B.2    Boudjemaa, S.3    Ananta, J.S.4    Morgant, G.5    Szwarc, H.6    Wilson, L.J.7    Moussa, F.8
  • 42
    • 84949770559 scopus 로고    scopus 로고
    • Toxicity studies of [60]fullerene and carbon nanotubes: state of the art
    • World Scientific, New Jersey, F. D'Souza, K.M. Kadish (Eds.) Handbook of Carbon Nano Materials
    • Kolosnjaj-Tabi J., Baati T., Szwarc H., Moussa F. Toxicity studies of [60]fullerene and carbon nanotubes: state of the art. Medical and Bio-related Applications 2012, vol. 3:49-81. World Scientific, New Jersey. F. D'Souza, K.M. Kadish (Eds.).
    • (2012) Medical and Bio-related Applications , vol.3 , pp. 49-81
    • Kolosnjaj-Tabi, J.1    Baati, T.2    Szwarc, H.3    Moussa, F.4
  • 43
    • 84915748313 scopus 로고    scopus 로고
    • Nanosafety research-are we on the right tract?
    • Krug H.F. Nanosafety research-are we on the right tract?. Angew. Chem. Int. Ed. 2014, 53:12304-12319.
    • (2014) Angew. Chem. Int. Ed. , vol.53 , pp. 12304-12319
    • Krug, H.F.1
  • 44
    • 1542726626 scopus 로고    scopus 로고
    • Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    • Lam C.Y., James J.T., McCluskey R., Hunter R.L. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 2004, 77:126-134.
    • (2004) Toxicol. Sci. , vol.77 , pp. 126-134
    • Lam, C.Y.1    James, J.T.2    McCluskey, R.3    Hunter, R.L.4
  • 49
    • 34547206282 scopus 로고    scopus 로고
    • Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation
    • Li J.G., Li W.L., Xu J.Y., Cai X.Q., Liu R.L., Li Y.J., Zhao Q.F., Li Q.N. Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation. Environ. Toxicol. 2007, 22:415-421.
    • (2007) Environ. Toxicol. , vol.22 , pp. 415-421
    • Li, J.G.1    Li, W.L.2    Xu, J.Y.3    Cai, X.Q.4    Liu, R.L.5    Li, Y.J.6    Zhao, Q.F.7    Li, Q.N.8
  • 50
    • 84891400033 scopus 로고    scopus 로고
    • A comparative study of lung toxicity in rats induced by three types of nanomaterials
    • Lin Z., Ma L., X Z., Zhang H., Lin B. A comparative study of lung toxicity in rats induced by three types of nanomaterials. Nanoscale Res. Lett. 2013, 8:521. 10.1186/1556-276x-8-521.
    • (2013) Nanoscale Res. Lett. , vol.8 , pp. 521
    • Lin, Z.1    Ma, L.2    Zhang, H.3    Lin, B.4
  • 51
    • 33748631281 scopus 로고    scopus 로고
    • Nanoparticles and their biological and environmental applications
    • Liu W.T. Nanoparticles and their biological and environmental applications. J. Biosci. Bioeng. 2006, 102:1-7.
    • (2006) J. Biosci. Bioeng. , vol.102 , pp. 1-7
    • Liu, W.T.1
  • 52
    • 33846845060 scopus 로고    scopus 로고
    • In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice
    • Liu Z., Cai W., He L., Nakayama N., Chen K., Sun X., Chen X., Dai H. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat. Nanotechnol. 2007, 2:47-52.
    • (2007) Nat. Nanotechnol. , vol.2 , pp. 47-52
    • Liu, Z.1    Cai, W.2    He, L.3    Nakayama, N.4    Chen, K.5    Sun, X.6    Chen, X.7    Dai, H.8
  • 53
    • 40349112868 scopus 로고    scopus 로고
    • Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
    • Liu Z., Davis C., Cai W., He L., Chen X., Dai H. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc. Natl. Acad. Sci. 2008, 105:1410-1415.
    • (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 1410-1415
    • Liu, Z.1    Davis, C.2    Cai, W.3    He, L.4    Chen, X.5    Dai, H.6
  • 54
    • 0032464139 scopus 로고    scopus 로고
    • High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2-deoxyguanosine excretion in rats
    • Loft S., Thorling E.B., Poulsen H.E. High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2-deoxyguanosine excretion in rats. Free Radic. Res. 1998, 29:595-600.
    • (1998) Free Radic. Res. , vol.29 , pp. 595-600
    • Loft, S.1    Thorling, E.B.2    Poulsen, H.E.3
  • 55
    • 33845667408 scopus 로고    scopus 로고
    • Single-walled carbon nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In situ
    • Mangum J.B., Turpin E.A., Antao-Menezes A., Cesta M., Bermudez E., Bonner J.C. Single-walled carbon nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In situ. Part. Fibre Toxicol. 2006, 3(15). 10.1186/1743-8977-3-15.
    • (2006) Part. Fibre Toxicol. , vol.3 , Issue.15
    • Mangum, J.B.1    Turpin, E.A.2    Antao-Menezes, A.3    Cesta, M.4    Bermudez, E.5    Bonner, J.C.6
  • 57
    • 1642503815 scopus 로고    scopus 로고
    • Exposure to carbon nanotubes material: aerosol release during the handling of unrefined single-walled carbon nanotube material
    • Maynard A.D., Baron P.A., Foley M., Shvedova A.A., Kisin E.R., Castranova V. Exposure to carbon nanotubes material: aerosol release during the handling of unrefined single-walled carbon nanotube material. J. Toxicol. Environ. Health 2004, 67:87-107.
    • (2004) J. Toxicol. Environ. Health , vol.67 , pp. 87-107
    • Maynard, A.D.1    Baron, P.A.2    Foley, M.3    Shvedova, A.A.4    Kisin, E.R.5    Castranova, V.6
  • 68
    • 84885438020 scopus 로고    scopus 로고
    • Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats
    • Nagai H., Okazaki Y., Chew S.H., Misawa N., Miyata Y., Shinohara H., Toyokuni S. Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats. Pathol. Int. 2013, 63:457-462.
    • (2013) Pathol. Int. , vol.63 , pp. 457-462
    • Nagai, H.1    Okazaki, Y.2    Chew, S.H.3    Misawa, N.4    Miyata, Y.5    Shinohara, H.6    Toyokuni, S.7
  • 69
    • 80053587356 scopus 로고    scopus 로고
    • Evaluation of the genotoxic potential of single-walled carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays
    • Naya M., Kobayashi N., Mizuno K., Matsumoto K., Ema M., Nakanishi J. Evaluation of the genotoxic potential of single-walled carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays. Regul. Toxicol. Pharmacol. 2011, 61:192-198.
    • (2011) Regul. Toxicol. Pharmacol. , vol.61 , pp. 192-198
    • Naya, M.1    Kobayashi, N.2    Mizuno, K.3    Matsumoto, K.4    Ema, M.5    Nakanishi, J.6
  • 71
    • 0035508412 scopus 로고    scopus 로고
    • Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamsters
    • Nemmar A., Vanbilloen H., Hoylaerts M.F., Hoet P.H.M., Verbruggen A., Nemery B. Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamsters. Am. J. Crit. Care Med. 2001, 164:1665-1688.
    • (2001) Am. J. Crit. Care Med. , vol.164 , pp. 1665-1688
    • Nemmar, A.1    Vanbilloen, H.2    Hoylaerts, M.F.3    Hoet, P.H.M.4    Verbruggen, A.5    Nemery, B.6
  • 72
  • 75
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolution from studies of ultrafine particles
    • Oberdörster G., Oberdörster E., Oberdörster J. Nanotoxicology: an emerging discipline evolution from studies of ultrafine particles. Environ. Health Perspect. 2005, 113:823-839.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 823-839
    • Oberdörster, G.1    Oberdörster, E.2    Oberdörster, J.3
  • 76
    • 79956101542 scopus 로고    scopus 로고
    • Release potential of single-wall carbon nanotubes produced by super-growth method during manufacturing and handling
    • Ogura I., Sakurai H., Mizuno K., Gamo M. Release potential of single-wall carbon nanotubes produced by super-growth method during manufacturing and handling. J. Nanopart. Res. 2011, 13:1265-1280.
    • (2011) J. Nanopart. Res. , vol.13 , pp. 1265-1280
    • Ogura, I.1    Sakurai, H.2    Mizuno, K.3    Gamo, M.4
  • 78
    • 85033518600 scopus 로고    scopus 로고
    • Intratracheal inhalation vs intratracheal instillation: differences in particle effects
    • Osier M., Oberdörster G. Intratracheal inhalation vs intratracheal instillation: differences in particle effects. Fundam. Appl. Toxicol. 1997, 40:220-227.
    • (1997) Fundam. Appl. Toxicol. , vol.40 , pp. 220-227
    • Osier, M.1    Oberdörster, G.2
  • 79
    • 80052699285 scopus 로고    scopus 로고
    • A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice
    • Park E.J., Roh J., Kim S.N., Kang M.S., Han Y.A., Kim Y., Hong J.T., Choi K. A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice. Arch. Toxicol. 2011, 85:1121-1131.
    • (2011) Arch. Toxicol. , vol.85 , pp. 1121-1131
    • Park, E.J.1    Roh, J.2    Kim, S.N.3    Kang, M.S.4    Han, Y.A.5    Kim, Y.6    Hong, J.T.7    Choi, K.8
  • 81
    • 78650487003 scopus 로고    scopus 로고
    • Biochemical and histopathological evaluation of functionalized single-walled carbon nanotube in Swiss-Webster mice
    • Patlolla A., McGinnis B., Tchounwou P. Biochemical and histopathological evaluation of functionalized single-walled carbon nanotube in Swiss-Webster mice. J. Appl. Toxicol. 2011, 31:75-83.
    • (2011) J. Appl. Toxicol. , vol.31 , pp. 75-83
    • Patlolla, A.1    McGinnis, B.2    Tchounwou, P.3
  • 83
    • 82155175728 scopus 로고    scopus 로고
    • Investigating the effects of functionalized carbon nanotubes on reproduction and development in Drosophila melanogaster and CD-1 mice
    • Philbrook N.A., Walker V.K., Afrooz A.R.M.N., Saleh N.B., Winn L.M. Investigating the effects of functionalized carbon nanotubes on reproduction and development in Drosophila melanogaster and CD-1 mice. Reprod. Toxicol. 2011, 32:442-448.
    • (2011) Reprod. Toxicol. , vol.32 , pp. 442-448
    • Philbrook, N.A.1    Walker, V.K.2    Afrooz, A.R.M.N.3    Saleh, N.B.4    Winn, L.M.5
  • 86
    • 84880693748 scopus 로고    scopus 로고
    • Developmental neurotoxicity of engineered nanomaterials: identifying research needs to support human health risk assessment
    • Powers C.N., Bale A.S., Kraft A.D., Makris S.L., Trecki J., Cowden J., Hotchkiss A., Gillespire P.A. Developmental neurotoxicity of engineered nanomaterials: identifying research needs to support human health risk assessment. Toxicol. Sci. 2013, 134:225-242.
    • (2013) Toxicol. Sci. , vol.134 , pp. 225-242
    • Powers, C.N.1    Bale, A.S.2    Kraft, A.D.3    Makris, S.L.4    Trecki, J.5    Cowden, J.6    Hotchkiss, A.7    Gillespire, P.A.8
  • 89
    • 37349054623 scopus 로고    scopus 로고
    • Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-walled carbon nanotubes
    • Saxena R.V., Williams D., McGee K., Daniels M.J., Boykin E., Gilmour M.I. Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-walled carbon nanotubes. Nanotoxicology 2007, 1:291-300.
    • (2007) Nanotoxicology , vol.1 , pp. 291-300
    • Saxena, R.V.1    Williams, D.2    McGee, K.3    Daniels, M.J.4    Boykin, E.5    Gilmour, M.I.6
  • 93
    • 49549102011 scopus 로고    scopus 로고
    • Increased accumulation of neutrophil and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes
    • Shvedova A.A., Kisin E.R., Murray A.R., Kommineni C., Castranova V., Fadeel B., Kagan V.E. Increased accumulation of neutrophil and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes. Toxicol. Appl. Pharmacol. 2008, 231:235-240.
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 235-240
    • Shvedova, A.A.1    Kisin, E.R.2    Murray, A.R.3    Kommineni, C.4    Castranova, V.5    Fadeel, B.6    Kagan, V.E.7
  • 95
    • 59849113938 scopus 로고    scopus 로고
    • Mechanism of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus?
    • Shvedova A.A., Kisin E.R., Porter D., Kagan V.E., Fadeel B., Castranova V. Mechanism of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus?. Pharmacol. Ther. 2009, 121:192-204.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 192-204
    • Shvedova, A.A.1    Kisin, E.R.2    Porter, D.3    Kagan, V.E.4    Fadeel, B.5    Castranova, V.6
  • 97
  • 101
    • 84925585586 scopus 로고    scopus 로고
    • Carbon nanotube structure, synthesis, and application
    • Cambridge University Press, Cambridge, K. Donaldson, C. Poland, R. Duffin, J. Bonner (Eds.)
    • Singh C., Song W. Carbon nanotube structure, synthesis, and application. The Toxicology of Carbon Nanotubes 2012, 1-37. Cambridge University Press, Cambridge. K. Donaldson, C. Poland, R. Duffin, J. Bonner (Eds.).
    • (2012) The Toxicology of Carbon Nanotubes , pp. 1-37
    • Singh, C.1    Song, W.2
  • 105
    • 69049117178 scopus 로고    scopus 로고
    • Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice
    • Tong H., McGee J.K., Saxena R.K., Kodavanti U.P., Devlin R.B., Gilmour M.I. Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice. Toxicol. Appl. Pharmacol. 2009, 239:224-232.
    • (2009) Toxicol. Appl. Pharmacol. , vol.239 , pp. 224-232
    • Tong, H.1    McGee, J.K.2    Saxena, R.K.3    Kodavanti, U.P.4    Devlin, R.B.5    Gilmour, M.I.6
  • 108
    • 30744461850 scopus 로고    scopus 로고
    • Rapidly functionalized, water-dispersed carbon nanotubes at high concentration
    • Wang Y., Iqbal Z., Mitra S. Rapidly functionalized, water-dispersed carbon nanotubes at high concentration. Am. J. Chem. Soc. 2006, 95:95-99.
    • (2006) Am. J. Chem. Soc. , vol.95 , pp. 95-99
    • Wang, Y.1    Iqbal, Z.2    Mitra, S.3
  • 109
    • 77957894948 scopus 로고    scopus 로고
    • Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies
    • Wang L., Castranova V., Mishra A., Chen B., Mercer R.R., Schwegler-Berry D., Rajanasakul Y. Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies. Part. Fibre Toxicol. 2010, 7:31. 10.1186/1743-8977-31.
    • (2010) Part. Fibre Toxicol. , vol.7 , pp. 31
    • Wang, L.1    Castranova, V.2    Mishra, A.3    Chen, B.4    Mercer, R.R.5    Schwegler-Berry, D.6    Rajanasakul, Y.7
  • 114
    • 52049100604 scopus 로고    scopus 로고
    • Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice
    • Yang S.T., Wang X., Jia G., Gu Y., Wang T., Nie H., Ge C., Wang H., Liu Y. Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice. Toxicol. Lett. 2008, 181:182-189.
    • (2008) Toxicol. Lett. , vol.181 , pp. 182-189
    • Yang, S.T.1    Wang, X.2    Jia, G.3    Gu, Y.4    Wang, T.5    Nie, H.6    Ge, C.7    Wang, H.8    Liu, Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.