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Volumn 6, Issue 7, 2015, Pages

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CALCINEURIN; CASPASE; FK 506 BINDING PROTEIN; FK506 BINDING PROTEIN 12.6; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INHIBITOR OF APOPTOSIS PROTEIN; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NUCLEAR RESPIRATORY FACTOR; PEPTIDES AND PROTEINS; PLECKSTRIN; PROTEIN KINASE R LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN SERINE THREONINE KINASE; T CELL DEATH ASSOCIATED GENE 51 PROTEIN; TRIBBLES HOMOLOG 3 PROTEIN; UNCLASSIFIED DRUG; EIF2AK3 PROTEIN, HUMAN; PROTEIN KINASE R;

EID: 84949111233     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.183     Document Type: Review
Times cited : (219)

References (102)
  • 1
    • 34047192683 scopus 로고    scopus 로고
    • Review. The endoplasmic reticulum: A target for new anticancer drugs
    • Boelens J, Lust S, Offner F, Bracke ME, Vanhoecke BW Review. The endoplasmic reticulum: a target for new anticancer drugs. In Vivo 2007; 21: 215-226.
    • (2007) In Vivo , vol.21 , pp. 215-226
    • Boelens, J.1    Lust, S.2    Offner, F.3    Bracke, M.E.4    Vanhoecke, B.W.5
  • 2
    • 34548419344 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease
    • Gregor MF, Hotamisligil GS. Thematic review series: adipocyte biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res 2007; 48: 1905-1914.
    • (2007) J Lipid Res , vol.48 , pp. 1905-1914
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 3
    • 0344988979 scopus 로고
    • The rough endoplasmic reticulum is the site of reserve-protein synthesis in developing phaseolus vulgaris cotyledons
    • Bollini R, Chrispeels MJ. The rough endoplasmic reticulum is the site of reserve-protein synthesis in developing Phaseolus vulgaris cotyledons. Planta 1979; 146: 487-501.
    • (1979) Planta , vol.146 , pp. 487-501
    • Bollini, R.1    Chrispeels, M.J.2
  • 4
    • 0023940624 scopus 로고
    • Post-translational protein modification in the endoplasmic reticulum. Demonstration of fatty acylase and deoxymannojirimycin-sensitive alpha-mannosidase activities
    • Rizzolo LJ, Kornfeld R. Post-translational protein modification in the endoplasmic reticulum. Demonstration of fatty acylase and deoxymannojirimycin-sensitive alpha-mannosidase activities. J Biol Chem 1988; 263: 9520-9525.
    • (1988) J Biol Chem , vol.263 , pp. 9520-9525
    • Rizzolo, L.J.1    Kornfeld, R.2
  • 5
    • 0019800032 scopus 로고
    • Studies on glucose-6-phosphatase, fructose-1,6-diphosphatase activity, glycogen distribution and endoplasmic reticulum changes during hexachlorocyclohexane induced hepatocarcinogenesis in pure inbred swiss mice
    • Karnik AB, Thakore KN, Nigam SK, Babu KA, Lakkad BC, Bhatt DK et al. Studies on glucose-6-phosphatase, fructose-1,6-diphosphatase activity, glycogen distribution and endoplasmic reticulum changes during hexachlorocyclohexane induced hepatocarcinogenesis in pure inbred Swiss mice. Neoplasma 1981; 28: 575-584.
    • (1981) Neoplasma , vol.28 , pp. 575-584
    • Karnik, A.B.1    Thakore, K.N.2    Nigam, S.K.3    Babu, K.A.4    Lakkad, B.C.5    Bhatt, D.K.6
  • 6
    • 0023785849 scopus 로고
    • Post-translational translocation of polypeptides across the mammalian endoplasmic reticulum membrane is size and ribosome dependent
    • Roitsch T, Lehle L. Post-translational translocation of polypeptides across the mammalian endoplasmic reticulum membrane is size and ribosome dependent. Eur J Biochem 1988; 174: 699-705.
    • (1988) Eur J Biochem , vol.174 , pp. 699-705
    • Roitsch, T.1    Lehle, L.2
  • 7
    • 34548651757 scopus 로고    scopus 로고
    • PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress
    • Kondratyev M, Avezov E, Shenkman M, Groisman B, Lederkremer GZ. PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress. Exp Cell Res 2007; 313: 3395-3407.
    • (2007) Exp Cell Res , vol.313 , pp. 3395-3407
    • Kondratyev, M.1    Avezov, E.2    Shenkman, M.3    Groisman, B.4    Lederkremer, G.Z.5
  • 8
    • 0034644111 scopus 로고    scopus 로고
    • ER stress response: Getting the UPR hand on misfolded proteins
    • Hampton RY. ER stress response: getting the UPR hand on misfolded proteins. Curr Biol 2000; 10: R518-R521.
    • (2000) Curr Biol , vol.10 , pp. R518-R521
    • Hampton, R.Y.1
  • 9
    • 0023852783 scopus 로고
    • The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
    • Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 1988; 332: 462-464.
    • (1988) Nature , vol.332 , pp. 462-464
    • Kozutsumi, Y.1    Segal, M.2    Normington, K.3    Gething, M.J.4    Sambrook, J.5
  • 10
    • 18344388462 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program: Role of the ER chaperone GRP78
    • Rao RV, Peel A, Logvinova A, del Rio G, Hermel E, Yokota T et al. Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78. FEBS Lett 2002; 514: 122-128.
    • (2002) FEBS Lett , vol.514 , pp. 122-128
    • Rao, R.V.1    Peel, A.2    Logvinova, A.3    Del Rio, G.4    Hermel, E.5    Yokota, T.6
  • 11
    • 84857868016 scopus 로고    scopus 로고
    • Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells
    • Lajoie P, Moir RD, Willis IM, Snapp EL. Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells. Mol Biol Cell 2012; 23: 955-964.
    • (2012) Mol Biol Cell , vol.23 , pp. 955-964
    • Lajoie, P.1    Moir, R.D.2    Willis, I.M.3    Snapp, E.L.4
  • 12
    • 84878225746 scopus 로고    scopus 로고
    • Functional and morphological impact of ER stress on mitochondria
    • Vannuvel K, Renard P, Raes M, Arnould T. Functional and morphological impact of ER stress on mitochondria. J Cell Physiol 2013; 228: 1802-1818.
    • (2013) J Cell Physiol , vol.228 , pp. 1802-1818
    • Vannuvel, K.1    Renard, P.2    Raes, M.3    Arnould, T.4
  • 13
    • 0038080911 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation
    • Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J Biol Chem 2003; 278: 20915-20924.
    • (2003) J Biol Chem , vol.278 , pp. 20915-20924
    • Reddy, R.K.1    Mao, C.2    Baumeister, P.3    Austin, R.C.4    Kaufman, R.J.5    Lee, A.S.6
  • 14
    • 15944366885 scopus 로고    scopus 로고
    • The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
    • Lee AS. The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods 2005; 35: 373-381.
    • (2005) Methods , vol.35 , pp. 373-381
    • Lee, A.S.1
  • 16
    • 0034515724 scopus 로고    scopus 로고
    • ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
    • Ye J, Rawson RB, Komuro R, Chen X, Dave UP, Prywes R et al. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 2000; 6: 1355-1364.
    • (2000) Mol Cell , vol.6 , pp. 1355-1364
    • Ye, J.1    Rawson, R.B.2    Komuro, R.3    Chen, X.4    Dave, U.P.5    Prywes, R.6
  • 17
    • 84898913480 scopus 로고    scopus 로고
    • ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response
    • Hirsch I, Weiwad M, Prell E, Ferrari DM. ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response. Apoptosis 2014; 19: 801-815.
    • (2014) Apoptosis , vol.19 , pp. 801-815
    • Hirsch, I.1    Weiwad, M.2    Prell, E.3    Ferrari, D.M.4
  • 18
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T et al. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 2002; 16: 452-466.
    • (2002) Genes Dev , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5    Okada, T.6
  • 19
    • 0037011917 scopus 로고    scopus 로고
    • IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
    • Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP et al. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002; 415: 92-96.
    • (2002) Nature , vol.415 , pp. 92-96
    • Calfon, M.1    Zeng, H.2    Urano, F.3    Till, J.H.4    Hubbard, S.R.5    Harding, H.P.6
  • 20
    • 79952708723 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in liver disease
    • Malhi H, Kaufman RJ. Endoplasmic reticulum stress in liver disease. J Hepatol 2011; 54: 795-809.
    • (2011) J Hepatol , vol.54 , pp. 795-809
    • Malhi, H.1    Kaufman, R.J.2
  • 21
    • 84887620237 scopus 로고    scopus 로고
    • ER stress-induced cell death mechanisms
    • Sano R, Reed JC. ER stress-induced cell death mechanisms. Biochim Biophys Acta 2013; 1833: 3460-3470.
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 3460-3470
    • Sano, R.1    Reed, J.C.2
  • 24
    • 30944458057 scopus 로고    scopus 로고
    • Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
    • Marciniak SJ, Garcia-Bonilla L, Hu J, Harding HP, Ron D. Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. J Cell Biol 2006; 172: 201-209.
    • (2006) J Cell Biol , vol.172 , pp. 201-209
    • Marciniak, S.J.1    Garcia-Bonilla, L.2    Hu, J.3    Harding, H.P.4    Ron, D.5
  • 25
    • 79952578365 scopus 로고    scopus 로고
    • Apolipoprotein E-deficient lipoproteins induce foam cell formation by activation of PERK-EIF-2alpha signaling cascade
    • Zhao Y, Guo Z, Lin X, Zhou L, Okoro EU, Fan G et al. Apolipoprotein E-deficient lipoproteins induce foam cell formation by activation of PERK-EIF-2alpha signaling cascade. J Bioanal Biomed 2010; 2: 113-120.
    • (2010) J Bioanal Biomed , vol.2 , pp. 113-120
    • Zhao, Y.1    Guo, Z.2    Lin, X.3    Zhou, L.4    Okoro, E.U.5    Fan, G.6
  • 26
    • 33846959081 scopus 로고    scopus 로고
    • HCV and CSFV IRES domain II mediate eIF2 release during 80 S ribosome assembly
    • Locker N, Easton LE, Lukavsky PJ. HCV and CSFV IRES domain II mediate eIF2 release during 80 S ribosome assembly. EMBO J 2007; 26: 795-805.
    • (2007) EMBO J , vol.26 , pp. 795-805
    • Locker, N.1    Easton, L.E.2    Lukavsky, P.J.3
  • 27
    • 3843117589 scopus 로고    scopus 로고
    • Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
    • Vattem KM, Wek RC. Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA 2004; 101: 11269-11274.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11269-11274
    • Vattem, K.M.1    Wek, R.C.2
  • 28
    • 35848935017 scopus 로고    scopus 로고
    • Translational control and the unfolded protein response
    • Wek RC, Cavener DR. Translational control and the unfolded protein response. Antioxid Redox Signal 2007; 9: 2357-2371.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 2357-2371
    • Wek, R.C.1    Cavener, D.R.2
  • 29
    • 79953000185 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2
    • Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR et al. Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2. J Biol Chem 2011; 286: 4809-4818.
    • (2011) J Biol Chem , vol.286 , pp. 4809-4818
    • Saito, A.1    Ochiai, K.2    Kondo, S.3    Tsumagari, K.4    Murakami, T.5    Cavener, D.R.6
  • 30
    • 79955656979 scopus 로고    scopus 로고
    • The structure of the PERK kinase domain suggests the mechanism for its activation
    • Cui W, Li J, Ron D, Sha B. The structure of the PERK kinase domain suggests the mechanism for its activation. Acta Crystallogr D 2011; 67: 423-428.
    • (2011) Acta Crystallogr D , vol.67 , pp. 423-428
    • Cui, W.1    Li, J.2    Ron, D.3    Sha, B.4
  • 31
    • 84879294652 scopus 로고    scopus 로고
    • Low-dose radiation induces endoplasmic reticulum stress and activates PERK-CHOP signaling pathway in mouse testicular cells]
    • Fang F, Gong PS, Song XF, Gong SL, Wang ZC. Low-dose radiation induces endoplasmic reticulum stress and activates PERK-CHOP signaling pathway in mouse testicular cells]. Zhonghua Nan Ke Xue 2012; 18: 777-782.
    • (2012) Zhonghua Nan Ke Xue , vol.18 , pp. 777-782
    • Fang, F.1    Gong, P.S.2    Song, X.F.3    Gong, S.L.4    Wang, Z.C.5
  • 32
    • 8544283103 scopus 로고    scopus 로고
    • CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
    • Yamaguchi H, Wang HG. CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 2004; 279: 45495-45502.
    • (2004) J Biol Chem , vol.279 , pp. 45495-45502
    • Yamaguchi, H.1    Wang, H.G.2
  • 33
    • 0031609760 scopus 로고    scopus 로고
    • The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum
    • Frand AR, Kaiser CA. The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum. Mol Cell 1998; 1: 161-170.
    • (1998) Mol Cell , vol.1 , pp. 161-170
    • Frand, A.R.1    Kaiser, C.A.2
  • 34
    • 1342305497 scopus 로고    scopus 로고
    • Caspase-12 and ER-stress-mediated apoptosis: The story so far
    • Szegezdi E, Fitzgerald U, Samali A. Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann NY Acad Sci 2003; 1010: 186-194.
    • (2003) Ann NY Acad Sci , vol.1010 , pp. 186-194
    • Szegezdi, E.1    Fitzgerald, U.2    Samali, A.3
  • 35
    • 72949122555 scopus 로고    scopus 로고
    • Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils
    • Binet F, Chiasson S, Girard D. Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils. Biochem Biophys Res Commun 2010; 391: 18-23.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 18-23
    • Binet, F.1    Chiasson, S.2    Girard, D.3
  • 36
    • 78649960531 scopus 로고    scopus 로고
    • Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells
    • Martinez JA, Zhang Z, Svetlov SI, Hayes RL, Wang KK, Larner SF. Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells. Apoptosis 2010; 15: 1480-1493.
    • (2010) Apoptosis , vol.15 , pp. 1480-1493
    • Martinez, J.A.1    Zhang, Z.2    Svetlov, S.I.3    Hayes, R.L.4    Wang, K.K.5    Larner, S.F.6
  • 37
    • 0035818467 scopus 로고    scopus 로고
    • Internal initiation in saccharomyces cerevisiae mediated by an initiator tRNA/eIF2-independent internal ribosome entry site element
    • Thompson SR, Gulyas KD, Sarnow P. Internal initiation in Saccharomyces cerevisiae mediated by an initiator tRNA/eIF2-independent internal ribosome entry site element. Proc Natl Acad Sci USA 2001; 98: 12972-12977.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12972-12977
    • Thompson, S.R.1    Gulyas, K.D.2    Sarnow, P.3
  • 38
    • 84984876795 scopus 로고    scopus 로고
    • Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2alpha dephosphorylation
    • Chambers JE, Dalton LE, Clarke HJ, Malzer E, Dominicus CS, Patel V et al. Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2alpha dephosphorylation. eLife 2015; 4: e04872.
    • (2015) ELife , vol.4
    • Chambers, J.E.1    Dalton, L.E.2    Clarke, H.J.3    Malzer, E.4    Dominicus, C.S.5    Patel, V.6
  • 39
    • 84884997052 scopus 로고    scopus 로고
    • ER stress activating ATF4/CHOP-TNF-alpha signaling pathway contributes to alcohol-induced disruption of osteogenic lineage of multipotential mesenchymal stem cell
    • Chen Y, Gao H, Yin Q, Chen L, Dong P, Zhang X et al. ER stress activating ATF4/CHOP-TNF-alpha signaling pathway contributes to alcohol-induced disruption of osteogenic lineage of multipotential mesenchymal stem cell. Cell Physiol Biochem 2013; 32: 743-754.
    • (2013) Cell Physiol Biochem , vol.32 , pp. 743-754
    • Chen, Y.1    Gao, H.2    Yin, Q.3    Chen, L.4    Dong, P.5    Zhang, X.6
  • 40
    • 58049203872 scopus 로고    scopus 로고
    • C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
    • Su N, Kilberg MS. C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene. J Biol Chem 2008; 283: 35106-35117.
    • (2008) J Biol Chem , vol.283 , pp. 35106-35117
    • Su, N.1    Kilberg, M.S.2
  • 41
    • 84863985147 scopus 로고    scopus 로고
    • Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
    • Cao J, Dai DL, Yao L, Yu HH, Ning B, Zhang Q et al. Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway. Mol Cell Biochem 2012; 364: 115-129.
    • (2012) Mol Cell Biochem , vol.364 , pp. 115-129
    • Cao, J.1    Dai, D.L.2    Yao, L.3    Yu, H.H.4    Ning, B.5    Zhang, Q.6
  • 42
    • 84869027086 scopus 로고    scopus 로고
    • ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation
    • Qing G, Li B, Vu A, Skuli N, Walton ZE, Liu X et al. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell 2012; 22: 631-644.
    • (2012) Cancer Cell , vol.22 , pp. 631-644
    • Qing, G.1    Li, B.2    Vu, A.3    Skuli, N.4    Walton, Z.E.5    Liu, X.6
  • 43
    • 84911459987 scopus 로고    scopus 로고
    • Co-administration of ABT-737 and SAHA induces apoptosis, mediated by noxa upregulation, bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines
    • Foster KA, Jane EP, Premkumar DR, Morales A, Pollack IF. Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines. J Neurooncol 2014; 120: 459-472.
    • (2014) J Neurooncol , vol.120 , pp. 459-472
    • Foster, K.A.1    Jane, E.P.2    Premkumar, D.R.3    Morales, A.4    Pollack, I.F.5
  • 44
    • 0042845994 scopus 로고    scopus 로고
    • Apoptosis-resistance of hypoxic cells: Multiple factors involved and a role for IAP-2
    • Dong Z, Wang JZ, Yu F, Venkatachalam MA. Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. Am J Pathol 2003; 163: 663-671.
    • (2003) Am J Pathol , vol.163 , pp. 663-671
    • Dong, Z.1    Wang, J.Z.2    Yu, F.3    Venkatachalam, M.A.4
  • 47
    • 2342430610 scopus 로고    scopus 로고
    • Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element
    • Warnakulasuriyarachchi D, Cerquozzi S, Cheung HH, Holcik M. Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element. J Biol Chem 2004; 279: 17148-17157.
    • (2004) J Biol Chem , vol.279 , pp. 17148-17157
    • Warnakulasuriyarachchi, D.1    Cerquozzi, S.2    Cheung, H.H.3    Holcik, M.4
  • 49
    • 84882962273 scopus 로고    scopus 로고
    • TDAG51 deficiency promotes oxidative stress-induced apoptosis through the generation of reactive oxygen species in mouse embryonic fibroblasts
    • Park ES, Kim J, Ha TU, Choi JS, Soo Hong K, Rho J. TDAG51 deficiency promotes oxidative stress-induced apoptosis through the generation of reactive oxygen species in mouse embryonic fibroblasts. Exp Mol Med 2013; 45: e35.
    • (2013) Exp Mol Med , vol.45 , pp. e35
    • Park, E.S.1    Kim, J.2    Ha, T.U.3    Choi, J.S.4    Soo Hong, K.5    Rho, J.6
  • 50
    • 0041989674 scopus 로고    scopus 로고
    • TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia
    • Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG et al. TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia. J Biol Chem 2003; 278: 30317-30327.
    • (2003) J Biol Chem , vol.278 , pp. 30317-30327
    • Hossain, G.S.1    Van Thienen, J.V.2    Werstuck, G.H.3    Zhou, J.4    Sood, S.K.5    Dickhout, J.G.6
  • 51
    • 17144419252 scopus 로고    scopus 로고
    • Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhou J, Lhotak S, Hilditch BA, Austin RC. Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 2005; 111: 1814-1821.
    • (2005) Circulation , vol.111 , pp. 1814-1821
    • Zhou, J.1    Lhotak, S.2    Hilditch, B.A.3    Austin, R.C.4
  • 52
    • 79954416526 scopus 로고    scopus 로고
    • The cytoprotective role of the keap1-nrf2 pathway
    • Baird L, Dinkova-Kostova AT. The cytoprotective role of the Keap1-Nrf2 pathway. Arch Toxicol 2011; 85: 241-272.
    • (2011) Arch Toxicol , vol.85 , pp. 241-272
    • Baird, L.1    Dinkova-Kostova, A.T.2
  • 55
    • 84889889353 scopus 로고    scopus 로고
    • Nrf2 and nrf1 signaling and ER stress crosstalk: Implication for proteasomal degradation and autophagy
    • Digaleh H, Kiaei M, Khodagholi F. Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy. Cell Mol Life Sci 2013; 70: 4681-4694.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 4681-4694
    • Digaleh, H.1    Kiaei, M.2    Khodagholi, F.3
  • 56
    • 84919762436 scopus 로고    scopus 로고
    • Involvement of the nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress
    • Zhang B, Wang XQ, Chen HY, Liu BH. Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress. J Pharmacol Sci 2014; 126: 216-229.
    • (2014) J Pharmacol Sci , vol.126 , pp. 216-229
    • Zhang, B.1    Wang, X.Q.2    Chen, H.Y.3    Liu, B.H.4
  • 57
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
    • Cullinan SB, Diehl JA. Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 2006; 38: 317-332.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 58
    • 57449102900 scopus 로고    scopus 로고
    • TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis
    • Qian B, Wang H, Men X, Zhang W, Cai H, Xu S et al. TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis. J Endocrinol 2008; 199: 407-416.
    • (2008) J Endocrinol , vol.199 , pp. 407-416
    • Qian, B.1    Wang, H.2    Men, X.3    Zhang, W.4    Cai, H.5    Xu, S.6
  • 59
    • 67651183896 scopus 로고    scopus 로고
    • Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain
    • Ishikawa F, Akimoto T, Yamamoto H, Araki Y, Yoshie T, Mori K et al. Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain. J Biochem 2009; 146: 123-132.
    • (2009) J Biochem , vol.146 , pp. 123-132
    • Ishikawa, F.1    Akimoto, T.2    Yamamoto, H.3    Araki, Y.4    Yoshie, T.5    Mori, K.6
  • 60
    • 84897494593 scopus 로고    scopus 로고
    • Ionizing radiation activates PERK/eIF2alpha/ATF4 signaling via ER stress-independent pathway in human vascular endothelial cells
    • Kim EJ, Lee YJ, Kang S, Lim YB. Ionizing radiation activates PERK/eIF2alpha/ATF4 signaling via ER stress-independent pathway in human vascular endothelial cells. Int J Radiat Biol 2014; 90: 306-312.
    • (2014) Int J Radiat Biol , vol.90 , pp. 306-312
    • Kim, E.J.1    Lee, Y.J.2    Kang, S.3    Lim, Y.B.4
  • 61
    • 33748774661 scopus 로고    scopus 로고
    • Calcium-sensitive mitochondrial membrane potential in human platelets and intrinsic signals of cell death
    • Leaver HA, Schou AC, Rizzo MT, Prowse CV. Calcium-sensitive mitochondrial membrane potential in human platelets and intrinsic signals of cell death. Platelets 2006; 17: 368-377.
    • (2006) Platelets , vol.17 , pp. 368-377
    • Leaver, H.A.1    Schou, A.C.2    Rizzo, M.T.3    Prowse, C.V.4
  • 62
    • 84893210242 scopus 로고    scopus 로고
    • Dissociation of FK506-binding protein 12.6 kD from ryanodine receptor in bronchial smooth muscle cells in airway hyperresponsiveness in asthma
    • Du Y, Zhao J, Li X, Jin S, Ma WL, Mu Q et al. Dissociation of FK506-binding protein 12.6 kD from ryanodine receptor in bronchial smooth muscle cells in airway hyperresponsiveness in asthma. Am J Respir Cell Mol Biol 2014; 50: 398-408.
    • (2014) Am J Respir Cell Mol Biol , vol.50 , pp. 398-408
    • Du, Y.1    Zhao, J.2    Li, X.3    Jin, S.4    Ma, W.L.5    Mu, Q.6
  • 63
    • 84875608277 scopus 로고    scopus 로고
    • Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: Involvement of GRP78
    • Hammadi M, Oulidi A, Gackiere F, Katsogiannou M, Slomianny C, Roudbaraki M et al. Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78. FASEB J 2013; 27: 1600-1609.
    • (2013) FASEB J , vol.27 , pp. 1600-1609
    • Hammadi, M.1    Oulidi, A.2    Gackiere, F.3    Katsogiannou, M.4    Slomianny, C.5    Roudbaraki, M.6
  • 64
    • 84907717563 scopus 로고    scopus 로고
    • Protein kinase RNA-like endoplasmic reticulum kinase (PERK)/calcineurin signaling is a novel pathway regulating intracellular calcium accumulation which might be involved in ventricular arrhythmias in diabetic cardiomyopathy
    • Liu Z, Cai H, Zhu H, Toque H, Zhao N, Qiu C et al. Protein kinase RNA-like endoplasmic reticulum kinase (PERK)/calcineurin signaling is a novel pathway regulating intracellular calcium accumulation which might be involved in ventricular arrhythmias in diabetic cardiomyopathy. Cell Signal 2014; 26: 2591-2600.
    • (2014) Cell Signal , vol.26 , pp. 2591-2600
    • Liu, Z.1    Cai, H.2    Zhu, H.3    Toque, H.4    Zhao, N.5    Qiu, C.6
  • 65
    • 84868197448 scopus 로고    scopus 로고
    • Programmed cell death pathways in cancer: A review of apoptosis, autophagy and programmed necrosis
    • Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B et al. Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif 2012; 45: 487-498.
    • (2012) Cell Prolif , vol.45 , pp. 487-498
    • Ouyang, L.1    Shi, Z.2    Zhao, S.3    Wang, F.T.4    Zhou, T.T.5    Liu, B.6
  • 66
    • 33750974189 scopus 로고    scopus 로고
    • Endoplasmic reticulum and golgi complex: Contributions to, and turnover by, autophagy
    • Mijaljica D, Prescott M, Devenish RJ. Endoplasmic reticulum and Golgi complex: contributions to, and turnover by, autophagy. Traffic 2006; 7: 1590-1595.
    • (2006) Traffic , vol.7 , pp. 1590-1595
    • Mijaljica, D.1    Prescott, M.2    Devenish, R.J.3
  • 67
    • 33749579383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress triggers autophagy
    • Yorimitsu T, Nair U, Yang Z, Klionsky DJ. Endoplasmic reticulum stress triggers autophagy. J Biol Chem 2006; 281: 30299-30304.
    • (2006) J Biol Chem , vol.281 , pp. 30299-30304
    • Yorimitsu, T.1    Nair, U.2    Yang, Z.3    Klionsky, D.J.4
  • 68
    • 33947386684 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: A new pathway to induce autophagy
    • Yorimitsu T, Klionsky DJ. Endoplasmic reticulum stress: a new pathway to induce autophagy. Autophagy 2007; 3: 160-162.
    • (2007) Autophagy , vol.3 , pp. 160-162
    • Yorimitsu, T.1    Klionsky, D.J.2
  • 69
    • 66449115318 scopus 로고    scopus 로고
    • Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
    • Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia A et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 2009; 119: 1359-1372.
    • (2009) J Clin Invest , vol.119 , pp. 1359-1372
    • Salazar, M.1    Carracedo, A.2    Salanueva, I.J.3    Hernandez-Tiedra, S.4    Lorente, M.5    Egia, A.6
  • 70
    • 56349138968 scopus 로고    scopus 로고
    • DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death
    • Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H et al. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ 2008; 15: 1875-1886.
    • (2008) Cell Death Differ , vol.15 , pp. 1875-1886
    • Gozuacik, D.1    Bialik, S.2    Raveh, T.3    Mitou, G.4    Shohat, G.5    Sabanay, H.6
  • 71
    • 84890861050 scopus 로고    scopus 로고
    • Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3
    • Rubiolo JA, Lopez-Alonso H, Martinez P, Millan A, Cagide E, Vieytes MR et al. Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3. Cell Signal 2014; 26: 419-432.
    • (2014) Cell Signal , vol.26 , pp. 419-432
    • Rubiolo, J.A.1    Lopez-Alonso, H.2    Martinez, P.3    Millan, A.4    Cagide, E.5    Vieytes, M.R.6
  • 72
    • 84907856144 scopus 로고    scopus 로고
    • Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1
    • Gade P, Manjegowda SB, Nallar SC, Maachani UB, Cross AS, Kalvakolanu DV. Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1. Mol Cell Biol 2014; 34: 4033-4048.
    • (2014) Mol Cell Biol , vol.34 , pp. 4033-4048
    • Gade, P.1    Manjegowda, S.B.2    Nallar, S.C.3    Maachani, U.B.4    Cross, A.S.5    Kalvakolanu, D.V.6
  • 73
    • 84872311621 scopus 로고    scopus 로고
    • XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation
    • Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S et al. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem 2013; 288: 859-872.
    • (2013) J Biol Chem , vol.288 , pp. 859-872
    • Margariti, A.1    Li, H.2    Chen, T.3    Martin, D.4    Vizcay-Barrena, G.5    Alam, S.6
  • 74
    • 36849062033 scopus 로고    scopus 로고
    • Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines
    • Gomez BP, Riggins RB, Shajahan AN, Klimach U, Wang A, Crawford AC et al. Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines. FASEB J 2007; 21: 4013-4027.
    • (2007) FASEB J , vol.21 , pp. 4013-4027
    • Gomez, B.P.1    Riggins, R.B.2    Shajahan, A.N.3    Klimach, U.4    Wang, A.5    Crawford, A.C.6
  • 76
    • 42149123787 scopus 로고    scopus 로고
    • Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1
    • Gade P, Roy SK, Li H, Nallar SC, Kalvakolanu DV. Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1. Mol Cell Biol 2008; 28: 2528-2548.
    • (2008) Mol Cell Biol , vol.28 , pp. 2528-2548
    • Gade, P.1    Roy, S.K.2    Li, H.3    Nallar, S.C.4    Kalvakolanu, D.V.5
  • 77
    • 81255177778 scopus 로고    scopus 로고
    • Temporal orchestration of circadian autophagy rhythm by C/EBPbeta
    • Ma D, Panda S, Lin JD. Temporal orchestration of circadian autophagy rhythm by C/EBPbeta. EMBO J 2011; 30: 4642-4651.
    • (2011) EMBO J , vol.30 , pp. 4642-4651
    • Ma, D.1    Panda, S.2    Lin, J.D.3
  • 78
    • 84881299126 scopus 로고    scopus 로고
    • Transactivation of atg4b by C/EBPbeta promotes autophagy to facilitate adipogenesis
    • Guo L, Huang JX, Liu Y, Li X, Zhou SR, Qian SW et al. Transactivation of Atg4b by C/EBPbeta promotes autophagy to facilitate adipogenesis. Mol Cell Biol 2013; 33: 3180-3190.
    • (2013) Mol Cell Biol , vol.33 , pp. 3180-3190
    • Guo, L.1    Huang, J.X.2    Liu, Y.3    Li, X.4    Zhou, S.R.5    Qian, S.W.6
  • 79
    • 83455169115 scopus 로고    scopus 로고
    • IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux
    • Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW et al. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux. Hum Mol Genet 2012; 21: 101-114.
    • (2012) Hum Mol Genet , vol.21 , pp. 101-114
    • Lee, H.1    Noh, J.Y.2    Oh, Y.3    Kim, Y.4    Chang, J.W.5    Chung, C.W.6
  • 80
    • 84879584007 scopus 로고    scopus 로고
    • Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions
    • Choi MS, Kim Y, Jung JY, Yang SH, Lee TR, Shin DW. Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions. Exp Dermatol 2013; 22: 491-494.
    • (2013) Exp Dermatol , vol.22 , pp. 491-494
    • Choi, M.S.1    Kim, Y.2    Jung, J.Y.3    Yang, S.H.4    Lee, T.R.5    Shin, D.W.6
  • 81
    • 84862977176 scopus 로고    scopus 로고
    • An IFN-gamma-stimulated ATF6-C/EBP-beta-signaling pathway critical for the expression of death associated protein kinase 1 and induction of autophagy
    • Gade P, Ramachandran G, Maachani UB, Rizzo MA, Okada T, Prywes R et al. An IFN-gamma-stimulated ATF6-C/EBP-beta-signaling pathway critical for the expression of death associated protein kinase 1 and induction of autophagy. Proc Natl Acad Sci USA 2012; 109: 10316-10321.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 10316-10321
    • Gade, P.1    Ramachandran, G.2    Maachani, U.B.3    Rizzo, M.A.4    Okada, T.5    Prywes, R.6
  • 82
    • 33846211417 scopus 로고    scopus 로고
    • ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
    • Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H et al. ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ 2007; 14: 230-239.
    • (2007) Cell Death Differ , vol.14 , pp. 230-239
    • Kouroku, Y.1    Fujita, E.2    Tanida, I.3    Ueno, T.4    Isoai, A.5    Kumagai, H.6
  • 86
    • 84912528393 scopus 로고    scopus 로고
    • mTOR and autophagy: A dynamic relationship governed by nutrients and energy
    • Dunlop EA, Tee AR. mTOR and autophagy: a dynamic relationship governed by nutrients and energy. Semin Cell Dev Biol 2014; 36: 121-129.
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 121-129
    • Dunlop, E.A.1    Tee, A.R.2
  • 87
    • 84859360525 scopus 로고    scopus 로고
    • Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
    • Shi WY, Xiao D, Wang L, Dong LH, Yan ZX, Shen ZX et al. Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy. Cell Death Dis 2012; 3: e275.
    • (2012) Cell Death Dis , vol.3 , pp. e275
    • Shi, W.Y.1    Xiao, D.2    Wang, L.3    Dong, L.H.4    Yan, Z.X.5    Shen, Z.X.6
  • 88
    • 84925270605 scopus 로고    scopus 로고
    • Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2alpha/ATF4 axis in selenite-treated NB4 cells
    • Jiang Q, Li F, Shi K, Wu P, An J, Yang Y et al. Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2alpha/ATF4 axis in selenite-treated NB4 cells. Cell Death Dis 2014; 5: e1270.
    • (2014) Cell Death Dis , vol.5
    • Jiang, Q.1    Li, F.2    Shi, K.3    Wu, P.4    An, J.5    Yang, Y.6
  • 89
    • 84880701227 scopus 로고    scopus 로고
    • ATF4 activation by the p38MAPK-eIF4E axis mediates apoptosis and autophagy induced by selenite in jurkat cells
    • Jiang Q, Li F, Shi K, Wu P, An J, Yang Y et al. ATF4 activation by the p38MAPK-eIF4E axis mediates apoptosis and autophagy induced by selenite in Jurkat cells. FEBS Lett 2013; 587: 2420-2429.
    • (2013) FEBS Lett , vol.587 , pp. 2420-2429
    • Jiang, Q.1    Li, F.2    Shi, K.3    Wu, P.4    An, J.5    Yang, Y.6
  • 90
    • 77951705616 scopus 로고    scopus 로고
    • HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at ser1046/1047 in human pancreatic cancer cells
    • Adachi S, Yasuda I, Nakashima M, Yamauchi T, Yamauchi J, Natsume H et al. HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells. Oncol Rep 2010; 23: 1709-1714.
    • (2010) Oncol Rep , vol.23 , pp. 1709-1714
    • Adachi, S.1    Yasuda, I.2    Nakashima, M.3    Yamauchi, T.4    Yamauchi, J.5    Natsume, H.6
  • 91
    • 84886730359 scopus 로고    scopus 로고
    • Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy
    • Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C et al. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy. Cardiovasc Diabetol 2013; 12: 158.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 158
    • Liu, Z.W.1    Zhu, H.T.2    Chen, K.L.3    Dong, X.4    Wei, J.5    Qiu, C.6
  • 92
    • 84870984470 scopus 로고    scopus 로고
    • PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
    • Verfaillie T, Rubio N, Garg AD, Bultynck G, Rizzuto R, Decuypere JP et al. PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress. Cell Death Differ 2012; 19: 1880-1891.
    • (2012) Cell Death Differ , vol.19 , pp. 1880-1891
    • Verfaillie, T.1    Rubio, N.2    Garg, A.D.3    Bultynck, G.4    Rizzuto, R.5    Decuypere, J.P.6
  • 93
    • 84926681917 scopus 로고    scopus 로고
    • Mitochondria-associated membranes (MAMs): Composition, molecular mechanisms and physiopathological implications
    • Pinton P, Giorgi C, Missiroli S, Patergnani S, Duszynski J, Wieckowski M. Mitochondria-associated membranes (MAMs): composition, molecular mechanisms and physiopathological implications. Antioxid Redox Signal 2015; 22: 995-1019.
    • (2015) Antioxid Redox Signal , vol.22 , pp. 995-1019
    • Pinton, P.1    Giorgi, C.2    Missiroli, S.3    Patergnani, S.4    Duszynski, J.5    Wieckowski, M.6
  • 94
    • 84902458305 scopus 로고    scopus 로고
    • The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress
    • Lin A, Yao J, Zhuang L, Wang D, Han J, Lam EW et al. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene 2014; 33: 3183-3194.
    • (2014) Oncogene , vol.33 , pp. 3183-3194
    • Lin, A.1    Yao, J.2    Zhuang, L.3    Wang, D.4    Han, J.5    Lam, E.W.6
  • 95
    • 84874268065 scopus 로고    scopus 로고
    • ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation
    • Zhang W, Hietakangas V, Wee S, Lim SC, Gunaratne J, Cohen SM. ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation. Genes Dev 2013; 27: 441-449.
    • (2013) Genes Dev , vol.27 , pp. 441-449
    • Zhang, W.1    Hietakangas, V.2    Wee, S.3    Lim, S.C.4    Gunaratne, J.5    Cohen, S.M.6
  • 96
    • 84879545572 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase kinase beta phosphorylation of sirtuin 1 in endothelium is atheroprotective
    • 2+/calmodulin-dependent protein kinase kinase beta phosphorylation of Sirtuin 1 in endothelium is atheroprotective. Proc Natl Acad Sci USA 2013; 110: E2420-7.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E2420-E2427
    • Wen, L.1    Chen, Z.2    Zhang, F.3    Cui, X.4    Sun, W.5    Geary, G.G.6
  • 97
    • 84954323123 scopus 로고    scopus 로고
    • Estrogen activates AMP-activated protein kinase in human endothelial cells via ERbeta/Ca/calmodulin-dependent protein kinase kinase beta pathway
    • Yang S, Wang J. Estrogen activates AMP-activated protein kinase in human endothelial cells via ERbeta/Ca/calmodulin-dependent protein kinase kinase beta pathway. Cell Biochem Biophys 2015; 24: 24.
    • (2015) Cell Biochem Biophys , vol.24 , pp. 24
    • Yang, S.1    Wang, J.2
  • 98
    • 84883453343 scopus 로고    scopus 로고
    • Suppression of eIF2alpha kinases alleviates Alzheimer's disease-related plasticity and memory deficits
    • Ma T, Trinh MA, Wexler AJ, Bourbon C, Gatti E, Pierre P et al. Suppression of eIF2alpha kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci 2013; 16: 1299-1305.
    • (2013) Nat Neurosci , vol.16 , pp. 1299-1305
    • Ma, T.1    Trinh, M.A.2    Wexler, A.J.3    Bourbon, C.4    Gatti, E.5    Pierre, P.6
  • 99
    • 84868135034 scopus 로고    scopus 로고
    • ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's disease
    • Hashida K, Kitao Y, Sudo H, Awa Y, Maeda S, Mori K et al. ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's disease. PLoS One 2012; 7: e47950.
    • (2012) PLoS One , vol.7
    • Hashida, K.1    Kitao, Y.2    Sudo, H.3    Awa, Y.4    Maeda, S.5    Mori, K.6
  • 100
    • 84864878269 scopus 로고    scopus 로고
    • Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
    • Vidal RL, Hetz C. Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease. Autophagy 2012; 8: 970-972.
    • (2012) Autophagy , vol.8 , pp. 970-972
    • Vidal, R.L.1    Hetz, C.2
  • 101
    • 84907157987 scopus 로고    scopus 로고
    • PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation
    • Meares GP, Liu Y, Rajbhandari R, Qin H, Nozell SE, Mobley JA et al. PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. Mol Cell Biol 2014; 34: 3911-3925.
    • (2014) Mol Cell Biol , vol.34 , pp. 3911-3925
    • Meares, G.P.1    Liu, Y.2    Rajbhandari, R.3    Qin, H.4    Nozell, S.E.5    Mobley, J.A.6
  • 102
    • 84891670635 scopus 로고    scopus 로고
    • PERK-eIF2alpha-ATF4-CHOP signaling contributes to TNFalpha-induced vascular calcification
    • Masuda M, Miyazaki-Anzai S, Levi M, Ting TC, Miyazaki M. PERK-eIF2alpha-ATF4-CHOP signaling contributes to TNFalpha-induced vascular calcification. J Am Heart Assoc 2013; 2: e000238.
    • (2013) J Am Heart Assoc , vol.2
    • Masuda, M.1    Miyazaki-Anzai, S.2    Levi, M.3    Ting, T.C.4    Miyazaki, M.5


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