ATF4 activation by the p38MAPK-eIF4E axis mediates apoptosis and autophagy induced by selenite in Jurkat cells

FEBS Letters

Volumn 587, Issue 15, 2013, Pages 2420-2429

  Jiang, Qian ^a   Li, Feng ^a   Shi, Kejian ^a   Wu, Pa ^a   An, Jiajia ^a   Yang, Yang ^a   Xu, Caimin ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Apoptosis; ATF4; Autophagy; eIF4E; p38MAPK; Sodium selenite

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BECLIN 1; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 4E; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P62; SELENITE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL METABOLISM; CHOP GENE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MAP1LC3B GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T CELL LEUKEMIA; TRANSCRIPTION INITIATION; UPREGULATION;

17-AAG; 17-ALLYLAMINO-DEMETHOXYGELDAMYCIN; APOPTOSIS; ATF4; AUTOPHAGY; EIF2Α; EIF4E; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT ALPHA; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E; HEAT SHOCK PROTEIN 90; HSP90; P38MAPK; S.C.; SODIUM SELENITE; SUBCUTANEOUS INJECTION;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; AUTOPHAGY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; JURKAT CELLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REAL-TIME POLYMERASE CHAIN REACTION; SODIUM SELENITE;

EID: 84880701227     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.06.011     Document Type: Article

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