Apolipoprotein E-deficient lipoproteins induce foam cell formation by activation of PERK-EIF-2α signaling cascade

Journal of Bioanalysis and Biomedicine

Volumn 2, Issue 5, 2010, Pages 113-120

  Zhao, YanFeng ^a,b   Guo, ZhongMao ^a,b   Lin, XingHua ^a   Zhou, LiChun ^a   Okoro, Emmanuel U ^a   Fan, GuoHuang ^c   Ramaswamy, Raju ^a   Yang, Hong ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b WUHAN UNIVERSITY   (China)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apolipoprotein E deficient lipoproteins; eIF 2 kinase; Endoplasmic reticulum stress; Eukaryotic initiation factor 2 ; Foam cells

Indexed keywords

ACID LIPASE; APOLIPOPROTEIN B48; APOLIPOPROTEIN E; CATHEPSIN B; CHOLESTEROL ESTER; INITIATION FACTOR 2ALPHA; LYSOSOME ENZYME; MESSENGER RNA; MUTANT PROTEIN; PROTEIN KINASE; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; FOAM CELL; LIPID STORAGE; LIPOPROTEIN SYNTHESIS; MACROPHAGE MIGRATION INHIBITION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSLATION REGULATION;

EID: 79952578365     PISSN: None     EISSN: 1948593X     Source Type: Journal    
DOI: 10.4172/1948-593X.1000033     Document Type: Article

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