메뉴 건너뛰기




Volumn 28, Issue 6, 2009, Pages 910-920

PERK-dependent regulation of IAP translation during ER stress

Author keywords

Apoptosis; ER stress; IAP; PERK

Indexed keywords

CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; PERK PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN DERIVATIVE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 60149106099     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.428     Document Type: Article
Times cited : (79)

References (63)
  • 1
    • 15244344356 scopus 로고    scopus 로고
    • A portrait of AKT kinases: Human cancer and animal models depict a family with strong individualities
    • Bellacosa A, Testa JR, Moore R, Larue L. (2004). A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities. Cancer Biol Ther 3: 268-275.
    • (2004) Cancer Biol Ther , vol.3 , pp. 268-275
    • Bellacosa, A.1    Testa, J.R.2    Moore, R.3    Larue, L.4
  • 2
    • 44949240664 scopus 로고    scopus 로고
    • cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
    • Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J et al. (2008). cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 30: 689-700.
    • (2008) Mol Cell , vol.30 , pp. 689-700
    • Bertrand, M.J.1    Milutinovic, S.2    Dickson, K.M.3    Ho, W.C.4    Boudreault, A.5    Durkin, J.6
  • 3
    • 27144458505 scopus 로고    scopus 로고
    • ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
    • Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N et al. (2005). ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J 24: 3470-3481.
    • (2005) EMBO J , vol.24 , pp. 3470-3481
    • Bi, M.1    Naczki, C.2    Koritzinsky, M.3    Fels, D.4    Blais, J.5    Hu, N.6
  • 4
    • 0033739622 scopus 로고    scopus 로고
    • PERK mediates cell-cycle exit during the mammalian unfolded protein response
    • Brewer JW, Diehl JA. (2000). PERK mediates cell-cycle exit during the mammalian unfolded protein response. Proc Natl Acad Sci USA 97: 12625-12630.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12625-12630
    • Brewer, J.W.1    Diehl, J.A.2
  • 5
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho H, Thorvaldsen JL, Chu Q, Feng F, Birnbaum MJ. (2001). Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem 276: 38349-38352.
    • (2001) J Biol Chem , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 7
    • 0027324844 scopus 로고
    • Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
    • Cox JS, Shamu CE, Walter P. (1993). Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73: 1197-1206.
    • (1993) Cell , vol.73 , pp. 1197-1206
    • Cox, J.S.1    Shamu, C.E.2    Walter, P.3
  • 8
    • 0027537461 scopus 로고
    • An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
    • Crook NE, Clem RJ, Miller LK. (1993). An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J Virol 67: 2168-2174.
    • (1993) J Virol , vol.67 , pp. 2168-2174
    • Crook, N.E.1    Clem, R.J.2    Miller, L.K.3
  • 10
    • 1242317030 scopus 로고    scopus 로고
    • Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
    • Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG et al. (2004). Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 279: 5405-5412.
    • (2004) J Biol Chem , vol.279 , pp. 5405-5412
    • Dan, H.C.1    Sun, M.2    Kaneko, S.3    Feldman, R.I.4    Nicosia, S.V.5    Wang, H.G.6
  • 11
    • 2342453921 scopus 로고    scopus 로고
    • Death receptors in chemotherapy and cancer
    • Debatin KM, Krammer PH. (2004). Death receptors in chemotherapy and cancer. Oncogene 23: 2950-2966.
    • (2004) Oncogene , vol.23 , pp. 2950-2966
    • Debatin, K.M.1    Krammer, P.H.2
  • 12
    • 8644282751 scopus 로고    scopus 로고
    • Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
    • Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N et al. (2004). Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 24: 10161-10168.
    • (2004) Mol Cell Biol , vol.24 , pp. 10161-10168
    • Deng, J.1    Lu, P.D.2    Zhang, Y.3    Scheuner, D.4    Kaufman, R.J.5    Sonenberg, N.6
  • 13
    • 38049155818 scopus 로고    scopus 로고
    • Deniaud A, Sharaf el dein O, Maillier E, Poncet D, Kroemer G, Lemaire C et al. (2008). Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 27: 285-299.
    • Deniaud A, Sharaf el dein O, Maillier E, Poncet D, Kroemer G, Lemaire C et al. (2008). Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 27: 285-299.
  • 14
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • Deveraux QL, Takahashi R, Salvesen GS, Reed JC. (1997). X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388: 300-304.
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 15
    • 33645124763 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism
    • Di Sano F, Ferraro E, Tufi R, Achsel T, Piacentini M, Cecconi F. (2006). Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem 281: 2693-2700.
    • (2006) J Biol Chem , vol.281 , pp. 2693-2700
    • Di Sano, F.1    Ferraro, E.2    Tufi, R.3    Achsel, T.4    Piacentini, M.5    Cecconi, F.6
  • 16
    • 33645640920 scopus 로고    scopus 로고
    • The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
    • Eckelman BP, Salvesen GS. (2006). The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 281: 3254-3260.
    • (2006) J Biol Chem , vol.281 , pp. 3254-3260
    • Eckelman, B.P.1    Salvesen, G.S.2
  • 17
    • 33751285479 scopus 로고    scopus 로고
    • The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth
    • Fels DR, Koumenis C. (2006). The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth. Cancer Biol Ther 5: 723-728.
    • (2006) Cancer Biol Ther , vol.5 , pp. 723-728
    • Fels, D.R.1    Koumenis, C.2
  • 18
    • 0037023688 scopus 로고    scopus 로고
    • Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner
    • Fernandez J, Bode B, Koromilas A, Diehl JA, Krukovets I, Snider MD et al (2002a). Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner. J Biol Chem 277: 11780-11787.
    • (2002) J Biol Chem , vol.277 , pp. 11780-11787
    • Fernandez, J.1    Bode, B.2    Koromilas, A.3    Diehl, J.A.4    Krukovets, I.5    Snider, M.D.6
  • 19
    • 0037166289 scopus 로고    scopus 로고
    • Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha
    • Fernandez J, Yaman I, Sarnow P, Snider MD, Hatzoglou M. (2002b). Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha. J Biol Chem 277: 19198-19205.
    • (2002) J Biol Chem , vol.277 , pp. 19198-19205
    • Fernandez, J.1    Yaman, I.2    Sarnow, P.3    Snider, M.D.4    Hatzoglou, M.5
  • 20
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M et al. (2000a). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6: 1099-1108.
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6
  • 21
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. (2000b). Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5: 897-904.
    • (2000) Mol Cell , vol.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 22
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
    • Harding HP, Zhang Y, Ron D. (1999). Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 23
    • 0032693671 scopus 로고    scopus 로고
    • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
    • Haze K, Yoshida H, Yanagi H, Yura T, Mori K. (1999). Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799.
    • (1999) Mol Biol Cell , vol.10 , pp. 3787-3799
    • Haze, K.1    Yoshida, H.2    Yanagi, H.3    Yura, T.4    Mori, K.5
  • 24
    • 2442432416 scopus 로고    scopus 로고
    • Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
    • Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y et al. (2004). Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 165: 347-356.
    • (2004) J Cell Biol , vol.165 , pp. 347-356
    • Hitomi, J.1    Katayama, T.2    Eguchi, Y.3    Kudo, T.4    Taniguchi, M.5    Koyama, Y.6
  • 25
    • 34249016897 scopus 로고    scopus 로고
    • Akt upand down-regulation in response to endoplasmic reticulum stress
    • Hosoi T, Hyoda K, Okuma Y, Nomura Y, Ozawa K. (2007). Akt upand down-regulation in response to endoplasmic reticulum stress. Brain Res 1152: 27-31.
    • (2007) Brain Res , vol.1152 , pp. 27-31
    • Hosoi, T.1    Hyoda, K.2    Okuma, Y.3    Nomura, Y.4    Ozawa, K.5
  • 26
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • Hu P, Han Z, Couvillon AD, Exton JH. (2004). Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem 279: 49420-49429.
    • (2004) J Biol Chem , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 27
    • 33645815074 scopus 로고    scopus 로고
    • Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
    • Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. (2006). Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol 26: 3071-3084.
    • (2006) Mol Cell Biol , vol.26 , pp. 3071-3084
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Kaufman, R.J.4    Exton, J.H.5
  • 28
    • 0029817451 scopus 로고    scopus 로고
    • Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME
    • Jamora C, Dennert G, Lee AS. (1996). Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci USA 93: 7690-7694.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7690-7694
    • Jamora, C.1    Dennert, G.2    Lee, A.S.3
  • 29
    • 0037306165 scopus 로고    scopus 로고
    • In vivo association of the stability control protein alphaCP with actively translating mRNAs
    • Ji X, Kong J, Liebhaber SA. (2003). In vivo association of the stability control protein alphaCP with actively translating mRNAs. Mol Cell Biol 23: 899-907.
    • (2003) Mol Cell Biol , vol.23 , pp. 899-907
    • Ji, X.1    Kong, J.2    Liebhaber, S.A.3
  • 30
    • 0043133837 scopus 로고    scopus 로고
    • Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses
    • Jiang HY, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR et al (2003). Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses. Mol Cell Biol 23: 5651-5663.
    • (2003) Mol Cell Biol , vol.23 , pp. 5651-5663
    • Jiang, H.Y.1    Wek, S.A.2    McGrath, B.C.3    Scheuner, D.4    Kaufman, R.J.5    Cavener, D.R.6
  • 32
    • 1542316306 scopus 로고    scopus 로고
    • Regulation of mRNA translation by protein folding in the endoplasmic reticulum
    • Kaufman RJ. (2004). Regulation of mRNA translation by protein folding in the endoplasmic reticulum. Trends Biochem Sci 29: 152-158.
    • (2004) Trends Biochem Sci , vol.29 , pp. 152-158
    • Kaufman, R.J.1
  • 33
    • 34548511321 scopus 로고    scopus 로고
    • A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway
    • Kazemi S, Mounir Z, Baltzis D, Raven JF, Wang S, Krishnamoorthy JL et al. (2007). A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway. Mol Biol Cell 18: 3635-3644.
    • (2007) Mol Biol Cell , vol.18 , pp. 3635-3644
    • Kazemi, S.1    Mounir, Z.2    Baltzis, D.3    Raven, J.F.4    Wang, S.5    Krishnamoorthy, J.L.6
  • 34
    • 33646373219 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced apoptosis: Multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
    • Li J, Lee B, Lee AS. (2006). Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J Biol Chem 281: 7260-7270.
    • (2006) J Biol Chem , vol.281 , pp. 7260-7270
    • Li, J.1    Lee, B.2    Lee, A.S.3
  • 35
    • 0346880501 scopus 로고    scopus 로고
    • The inhibitors of apoptosis: There is more to life than Bcl2
    • Liston P, Fong WG, Korneluk RG. (2003). The inhibitors of apoptosis: there is more to life than Bcl2. Oncogene 22: 8568-8580.
    • (2003) Oncogene , vol.22 , pp. 8568-8580
    • Liston, P.1    Fong, W.G.2    Korneluk, R.G.3
  • 36
    • 21244462014 scopus 로고    scopus 로고
    • BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death
    • Mathai JP, Germain M, Shore GC. (2005). BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 280: 23829-23836.
    • (2005) J Biol Chem , vol.280 , pp. 23829-23836
    • Mathai, J.P.1    Germain, M.2    Shore, G.C.3
  • 37
    • 0037072937 scopus 로고    scopus 로고
    • An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
    • Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y. (2002). An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294.
    • (2002) J Biol Chem , vol.277 , pp. 34287-34294
    • Morishima, N.1    Nakanishi, K.2    Takenouchi, H.3    Shibata, T.4    Yasuhiko, Y.5
  • 38
    • 9644295726 scopus 로고    scopus 로고
    • Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis
    • Morishima N, Nakanishi K, Tsuchiya K, Shibata T, Seiwa E. (2004). Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis. J Biol Chem 279: 50375-50381.
    • (2004) J Biol Chem , vol.279 , pp. 50375-50381
    • Morishima, N.1    Nakanishi, K.2    Tsuchiya, K.3    Shibata, T.4    Seiwa, E.5
  • 39
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA et al. (2000). Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103.
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6
  • 40
    • 0030910584 scopus 로고    scopus 로고
    • Bik and Bak induce apoptosis downstream of CrmA but upstream of inhibitor of apoptosis
    • Orth K, Dixit VM. (1997). Bik and Bak induce apoptosis downstream of CrmA but upstream of inhibitor of apoptosis. J Biol Chem 272: 8841-8844.
    • (1997) J Biol Chem , vol.272 , pp. 8841-8844
    • Orth, K.1    Dixit, V.M.2
  • 41
    • 35948994157 scopus 로고    scopus 로고
    • Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis
    • Petersen SL, Wang L, Yalcin-Chin A, Li L, Peyton M, Minna J et al. (2007). Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 12: 445-456.
    • (2007) Cancer Cell , vol.12 , pp. 445-456
    • Petersen, S.L.1    Wang, L.2    Yalcin-Chin, A.3    Li, L.4    Peyton, M.5    Minna, J.6
  • 43
    • 0037077254 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
    • Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del Rio G et al. (2002). Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 277: 21836-21842.
    • (2002) J Biol Chem , vol.277 , pp. 21836-21842
    • Rao, R.V.1    Castro-Obregon, S.2    Frankowski, H.3    Schuler, M.4    Stoka, V.5    del Rio, G.6
  • 44
    • 0042477717 scopus 로고    scopus 로고
    • Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
    • Reimertz C, Kogel D, Rami A, Chittenden T, Prehn JH. (2003). Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol 162: 587-597.
    • (2003) J Cell Biol , vol.162 , pp. 587-597
    • Reimertz, C.1    Kogel, D.2    Rami, A.3    Chittenden, T.4    Prehn, J.H.5
  • 45
    • 4344660747 scopus 로고    scopus 로고
    • XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
    • Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H et al. (2004). XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res 64: 5943-5947.
    • (2004) Cancer Res , vol.64 , pp. 5943-5947
    • Romero-Ramirez, L.1    Cao, H.2    Nelson, D.3    Hammond, E.4    Lee, A.H.5    Yoshida, H.6
  • 46
    • 0030698127 scopus 로고    scopus 로고
    • The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    • Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. (1997). The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 16: 6914-6925.
    • (1997) EMBO J , vol.16 , pp. 6914-6925
    • Roy, N.1    Deveraux, Q.L.2    Takahashi, R.3    Salvesen, G.S.4    Reed, J.C.5
  • 47
    • 0036088471 scopus 로고    scopus 로고
    • IAP proteins: Blocking the road to death's door
    • Salvesen GS, Duckett CS. (2002). IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 3: 401-410.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 401-410
    • Salvesen, G.S.1    Duckett, C.S.2
  • 48
    • 0034973982 scopus 로고    scopus 로고
    • Translational control is required for the unfolded protein response and in vivo glucose homeostasis
    • Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P et al. (2001). Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 7: 1165-1176.
    • (2001) Mol Cell , vol.7 , pp. 1165-1176
    • Scheuner, D.1    Song, B.2    McEwen, E.3    Liu, C.4    Laybutt, R.5    Gillespie, P.6
  • 49
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • Schroder M, Kaufman RJ. (2005). The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789.
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 50
    • 14844323968 scopus 로고    scopus 로고
    • XIAP inhibits caspase-3 and -7 using two binding sites: Evolutionarily conserved mechanism of IAPs
    • Scott FL, Denault JB, Riedl SJ, Shin H, Renatus M, Salvesen GS. (2005). XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs. EMBO J 24: 645-655.
    • (2005) EMBO J , vol.24 , pp. 645-655
    • Scott, F.L.1    Denault, J.B.2    Riedl, S.J.3    Shin, H.4    Renatus, M.5    Salvesen, G.S.6
  • 51
    • 0031755020 scopus 로고    scopus 로고
    • Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
    • Shi Y, Vattem KM, Sood R, An J, Liang J, Stramm L et al. (1998). Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 18: 7499-7509.
    • (1998) Mol Cell Biol , vol.18 , pp. 7499-7509
    • Shi, Y.1    Vattem, K.M.2    Sood, R.3    An, J.4    Liang, J.5    Stramm, L.6
  • 53
    • 33750440743 scopus 로고    scopus 로고
    • ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1
    • Shiraishi H, Okamoto H, Yoshimura A, Yoshida H. (2006). ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sci 119: 3958-3966.
    • (2006) J Cell Sci , vol.119 , pp. 3958-3966
    • Shiraishi, H.1    Okamoto, H.2    Yoshimura, A.3    Yoshida, H.4
  • 54
    • 0032902337 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons
    • Simons M, Beinroth S, Gleichmann M, Liston P, Korneluk RG, MacKenzie AE et al. (1999). Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. J Neurochem 72: 292-301.
    • (1999) J Neurochem , vol.72 , pp. 292-301
    • Simons, M.1    Beinroth, S.2    Gleichmann, M.3    Liston, P.4    Korneluk, R.G.5    MacKenzie, A.E.6
  • 55
    • 0032525990 scopus 로고    scopus 로고
    • A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
    • Tirasophon W, Welihinda AA, Kaufman RJ. (1998). A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 12: 1812-1824.
    • (1998) Genes Dev , vol.12 , pp. 1812-1824
    • Tirasophon, W.1    Welihinda, A.A.2    Kaufman, R.J.3
  • 56
    • 84883840386 scopus 로고
    • Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
    • Todaro GJ, Green H. (1963). Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 17: 299-313.
    • (1963) J Cell Biol , vol.17 , pp. 299-313
    • Todaro, G.J.1    Green, H.2
  • 57
    • 36048999753 scopus 로고    scopus 로고
    • IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
    • Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P et al. (2007). IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 131: 669-681.
    • (2007) Cell , vol.131 , pp. 669-681
    • Varfolomeev, E.1    Blankenship, J.W.2    Wayson, S.M.3    Fedorova, A.V.4    Kayagaki, N.5    Garg, P.6
  • 58
    • 3843117589 scopus 로고    scopus 로고
    • Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
    • Vattem KM, Wek RC. (2004). Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA 101: 11269-11274.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11269-11274
    • Vattem, K.M.1    Wek, R.C.2
  • 59
    • 36148954336 scopus 로고    scopus 로고
    • IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
    • Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU et al. (2007). IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 131: 682-693.
    • (2007) Cell , vol.131 , pp. 682-693
    • Vince, J.E.1    Wong, W.W.2    Khan, N.3    Feltham, R.4    Chau, D.5    Ahmed, A.U.6
  • 60
    • 35948950248 scopus 로고    scopus 로고
    • The inhibitor of apoptosis proteins as therapeutic targets in cancer
    • Vucic D, Fairbrother WJ. (2007). The inhibitor of apoptosis proteins as therapeutic targets in cancer. Clin Cancer Res 13: 5995-6000.
    • (2007) Clin Cancer Res , vol.13 , pp. 5995-6000
    • Vucic, D.1    Fairbrother, W.J.2
  • 61
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin Jr AS. (1998a). NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr, A.S.5
  • 62
    • 0032190546 scopus 로고    scopus 로고
    • Cloning of mammalian Ire1 reveals diversity in the ER stress responses
    • Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D. (1998b). Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 17: 5708-5717.
    • (1998) EMBO J , vol.17 , pp. 5708-5717
    • Wang, X.Z.1    Harding, H.P.2    Zhang, Y.3    Jolicoeur, E.M.4    Kuroda, M.5    Ron, D.6
  • 63
    • 2342430610 scopus 로고    scopus 로고
    • Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element
    • Warnakulasuriyarachchi D, Cerquozzi S, Cheung HH, Holcik M. (2004). Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element. J Biol Chem 279: 17148-17157.
    • (2004) J Biol Chem , vol.279 , pp. 17148-17157
    • Warnakulasuriyarachchi, D.1    Cerquozzi, S.2    Cheung, H.H.3    Holcik, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.