Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells

Cell Death and Disease

Volumn 5, Issue , 2014, Pages

  Jiang, Q ^a   Li, F ^a   Shi, K ^a   Wu, P ^a   An, J ^a   Yang, Y ^a   Xu, C ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Apoptosis; Autophagy; p38; p53; Selenite

Indexed keywords

3 METHYLADENINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 4; BAFILOMYCIN A1; BECLIN 1; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INITIATION FACTOR 4E; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3B; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; PKR LIKE ER KINASE; PROTEIN P53; SALUBRINAL; SMALL INTERFERING RNA; SODIUM SELENITE; UNCLASSIFIED DRUG; ATF4 PROTEIN, HUMAN; EIF2AK3 PROTEIN, HUMAN; INITIATION FACTOR 2; MAP1LC3C PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN KINASE R; SELENIOUS ACID; TP53 PROTEIN, HUMAN; TRACE ELEMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; AUTOPHOSPHORYLATION; CELL FATE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG MEGADOSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME SPECIFICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE TEST; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH; TUMOR VOLUME; TUNEL ASSAY; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA, PROMYELOCYTIC, ACUTE; METABOLISM; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE; XENOGRAFT;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION, LEUKEMIC; HETEROGRAFTS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM TRANSPLANTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RESPONSE ELEMENTS; SELENIOUS ACID; SIGNAL TRANSDUCTION; TRACE ELEMENTS; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84925270605     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.200     Document Type: Article

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