Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation

eLife

Volumn 2015, Issue 4, 2015, Pages

  Chambers, Joseph E ^a   Dalton, Lucy E ^a   Clarke, Hanna J ^a   Malzer, Elke ^a   Dominicus, Caia S ^a   Patel, Vruti ^a   Moorhead, Greg ^b   Ron, David ^a   Marciniak, Stefan J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; ANAZOLENE SODIUM; F ACTIN; G ACTIN; HYBRID PROTEIN; INITIATION FACTOR 2ALPHA; JASPAMIDE; LATRUNCULIN B; MONOCLONAL ANTIBODY; PENICILLOYL POLYLYSINE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOTRANSFERASE; PLASMID DNA; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15A; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B; THAPSIGARGIN; TUNICAMYCIN; UNCLASSIFIED DRUG; ACTIN; DEPSIPEPTIDE; INITIATION FACTOR 2; PPP1R15A PROTEIN, HUMAN; PROTEIN BINDING;

ACTIN POLYMERIZATION; ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; NONHUMAN; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; SILVER STAINING; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; PHYSIOLOGICAL STRESS;

ANIMALIA; EUKARYOTA;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; DEPSIPEPTIDES; DROSOPHILA MELANOGASTER; EUKARYOTIC INITIATION FACTOR-2; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PHOSPHATASE 1; STRESS, PHYSIOLOGICAL;

EID: 84984876795     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.04872     Document Type: Article

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