-
1
-
-
0033152742
-
Clearance of glutamate inside the synapse and beyond
-
Bergles, D. E., Diamond, J. S. & Jahr, C. E. Clearance of glutamate inside the synapse and beyond. Curr Opin Neurobiol 9, 293-298 (1999).
-
(1999)
Curr Opin Neurobiol
, vol.9
, pp. 293-298
-
-
Bergles, D.E.1
Diamond, J.S.2
Jahr, C.E.3
-
2
-
-
0033104066
-
Immunogold evidence suggests that coupling of K1 siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains
-
Nagelhus, E. A. et al. Immunogold evidence suggests that coupling of K1 siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. Glia 26, 47-54 (1999).
-
(1999)
Glia
, vol.26
, pp. 47-54
-
-
Nagelhus, E.A.1
-
3
-
-
34547761212
-
Astrocyte glycogen and brain energy metabolism
-
Brown, A. M. & Ransom, B. R. Astrocyte glycogen and brain energy metabolism. Glia 55, 1263-1271 (2007).
-
(2007)
Glia
, vol.55
, pp. 1263-1271
-
-
Brown, A.M.1
Ransom, B.R.2
-
4
-
-
2442622731
-
Contribution of astrocytes to synaptic transmission in the rat supraoptic nucleus
-
Piet, R., Poulain, D. A. & Oliet, S. H. Contribution of astrocytes to synaptic transmission in the rat supraoptic nucleus. Neurochem Int 45, 251-257 (2004).
-
(2004)
Neurochem Int
, vol.45
, pp. 251-257
-
-
Piet, R.1
Poulain, D.A.2
Oliet, S.H.3
-
5
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott, N. J., Ronnback, L. & Hansson, E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7, 41-53 (2006).
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
6
-
-
0038353652
-
Astrocyte-mediated control of cerebral microcirculation
-
author reply 344-345
-
Anderson, C. M. & Nedergaard, M. Astrocyte-mediated control of cerebral microcirculation. Trends Neurosci 26, 340-344; author reply 344-345 (2003).
-
(2003)
Trends Neurosci
, vol.26
, pp. 340-344
-
-
Anderson, C.M.1
Nedergaard, M.2
-
7
-
-
76349091357
-
Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharideinduced blood-brain barrier disruption through matrix metalloproteinase activity
-
Aid, S. et al. Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharideinduced blood-brain barrier disruption through matrix metalloproteinase activity. J Cereb Blood Flow Metab 30, 370-380 (2010).
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 370-380
-
-
Aid, S.1
-
8
-
-
20344373695
-
Multiple roles for MMPs and TIMPs in cerebral ischemia
-
Cunningham, L. A., Wetzel, M. & Rosenberg, G. A. Multiple roles for MMPs and TIMPs in cerebral ischemia. Glia 50, 329-339 (2005).
-
(2005)
Glia
, vol.50
, pp. 329-339
-
-
Cunningham, L.A.1
Wetzel, M.2
Rosenberg, G.A.3
-
9
-
-
1542317072
-
Reactive astrocytes protect tissue and preserve function after spinal cord injury
-
Faulkner, J. R. et al. Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci 24, 2143-2155 (2004).
-
(2004)
J Neurosci
, vol.24
, pp. 2143-2155
-
-
Faulkner, J.R.1
-
10
-
-
70349103383
-
Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS
-
Voskuhl, R. R. et al. Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J Neurosci 29, 11511-11522 (2009).
-
(2009)
J Neurosci
, vol.29
, pp. 11511-11522
-
-
Voskuhl, R.R.1
-
11
-
-
33751560062
-
Astrogliosis in EAE spinal cord: Derivation from radial glia, and relationships to oligodendroglia
-
Bannerman, P., Hahn, A., Soulika, A., Gallo, V. & Pleasure, D. Astrogliosis in EAE spinal cord: derivation from radial glia, and relationships to oligodendroglia. Glia 55, 57-64 (2007).
-
(2007)
Glia
, vol.55
, pp. 57-64
-
-
Bannerman, P.1
Hahn, A.2
Soulika, A.3
Gallo, V.4
Pleasure, D.5
-
12
-
-
0343570065
-
N-cadherin influences migration of oligodendrocytes on astrocyte monolayers
-
Schnadelbach, O. et al. N-cadherin influences migration of oligodendrocytes on astrocyte monolayers. Mol Cell Neurosci 15, 288-302 (2000).
-
(2000)
Mol Cell Neurosci
, vol.15
, pp. 288-302
-
-
Schnadelbach, O.1
-
13
-
-
35349024347
-
Induction of the genes for Cxcl9 and Cxcl10 is dependent on IFN-gamma but shows differential cellular expression in experimental autoimmune encephalomyelitis and by astrocytes and microglia in vitro
-
Carter, S. L., Muller, M., Manders, P. M. & Campbell, I. L. Induction of the genes for Cxcl9 and Cxcl10 is dependent on IFN-gamma but shows differential cellular expression in experimental autoimmune encephalomyelitis and by astrocytes and microglia in vitro. Glia 55, 1728-1739 (2007).
-
(2007)
Glia
, vol.55
, pp. 1728-1739
-
-
Carter, S.L.1
Muller, M.2
Manders, P.M.3
Campbell, I.L.4
-
14
-
-
0041319041
-
Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
-
Babcock, A. A., Kuziel, W. A., Rivest, S. & Owens, T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci 23, 7922-7930 (2003).
-
(2003)
J Neurosci
, vol.23
, pp. 7922-7930
-
-
Babcock, A.A.1
Kuziel, W.A.2
Rivest, S.3
Owens, T.4
-
15
-
-
0031033952
-
Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis
-
Glabinski, A. R., Tani, M, Strieter, R. M., Tuohy, V. K. & Ransohoff, R. M. Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am J Pathol 150, 617-630 (1997).
-
(1997)
Am J Pathol
, vol.150
, pp. 617-630
-
-
Glabinski, A.R.1
Tani, M.2
Strieter, R.M.3
Tuohy, V.K.4
Ransohoff, R.M.5
-
16
-
-
0027530096
-
Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis
-
Ransohoff, R. M. et al. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 7, 592-600 (1993).
-
(1993)
FASEB J
, vol.7
, pp. 592-600
-
-
Ransohoff, R.M.1
-
17
-
-
0029126861
-
Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
-
Deli, M. A. et al. Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin. J Neurosci Res 41, 717-726 (1995).
-
(1995)
J Neurosci Res
, vol.41
, pp. 717-726
-
-
Deli, M.A.1
-
18
-
-
0029908222
-
Differential permeability of the BBB in acute EAE: Enhanced transport of TNT-alpha
-
Pan, W., Banks, W. A., Kennedy, M. K., Gutierrez, E. G. & Kastin, A. J. Differential permeability of the BBB in acute EAE: enhanced transport of TNT-alpha. Am J Physiol 271, E636-642 (1996).
-
(1996)
Am J Physiol
, vol.271
, pp. E636-E642
-
-
Pan, W.1
Banks, W.A.2
Kennedy, M.K.3
Gutierrez, E.G.4
Kastin, A.J.5
-
19
-
-
0037971138
-
Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability
-
Didier, N. et al. Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability. J Neurochem 86, 246-254 (2003).
-
(2003)
J Neurochem
, vol.86
, pp. 246-254
-
-
Didier, N.1
-
20
-
-
74149093963
-
Astrocyte- and endothelial-targeted CCL2 conditional knockout mice: Critical tools for studying the pathogenesis of neuroinflammation
-
Ge, S., Murugesan, N. & Pachter, J. S. Astrocyte- and Endothelial-Targeted CCL2 Conditional Knockout Mice: Critical Tools for Studying the Pathogenesis of Neuroinflammation. J Mol Neurosci. 39, 269-283 (2009).
-
(2009)
J Mol Neurosci.
, vol.39
, pp. 269-283
-
-
Ge, S.1
Murugesan, N.2
Pachter, J.S.3
-
21
-
-
17044372405
-
CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study
-
Dos Santos, A. C. et al. CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study. J Neuroimmunol 162, 122-129 (2005).
-
(2005)
J Neuroimmunol
, vol.162
, pp. 122-129
-
-
Dos Santos, A.C.1
-
22
-
-
0036533663
-
IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
-
Dufour, J. H. et al. IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol 168, 3195-3204 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 3195-3204
-
-
Dufour, J.H.1
-
23
-
-
0035313548
-
CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses
-
Kielian, T., Barry, B. & Hickey, W. F. CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses. J Immunol 166, 4634-4643 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 4634-4643
-
-
Kielian, T.1
Barry, B.2
Hickey, W.F.3
-
24
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis, J. M. & Avruch, J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81, 807-869 (2001).
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
25
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
Roux, P. P. & Blenis, J. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68, 320-344 (2004).
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
26
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson, G. et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22, 153-183 (2001).
-
(2001)
Endocr Rev
, vol.22
, pp. 153-183
-
-
Pearson, G.1
-
27
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis, J. M. & Avruch, J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 271, 24313-24316 (1996).
-
(1996)
J Biol Chem
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
28
-
-
34249334506
-
P38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun. Pathway
-
Hui, L. et al. p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun. pathway. Nat Genet 39, 741-749 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 741-749
-
-
Hui, L.1
-
29
-
-
33645723895
-
The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells
-
Dodeller, F. & Schulze-Koops, H. The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells. Arthritis Res Ther 8, 205 (2006).
-
(2006)
Arthritis Res Ther
, vol.8
, pp. 205
-
-
Dodeller, F.1
Schulze-Koops, H.2
-
30
-
-
0034213138
-
P38 MAP kinases: Beyond the stress response
-
Nebreda, A. R. & Porras, A. p38 MAP kinases: beyond the stress response. Trends Biochem Sci 25, 257-260 (2000).
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 257-260
-
-
Nebreda, A.R.1
Porras, A.2
-
31
-
-
0033965158
-
The p38 signal transduction pathway: Activation and function
-
Ono, K. & Han, J. The p38 signal transduction pathway: activation and function. Cell Signal 12, 1-13 (2000).
-
(2000)
Cell Signal
, vol.12
, pp. 1-13
-
-
Ono, K.1
Han, J.2
-
32
-
-
0032850020
-
P38 MAPK signalling cascades in inflammatory disease
-
Herlaar, E. & Brown, Z. p38 MAPK signalling cascades in inflammatory disease. Mol Med Today 5, 439-447 (1999).
-
(1999)
Mol Med Today
, vol.5
, pp. 439-447
-
-
Herlaar, E.1
Brown, Z.2
-
33
-
-
50049122380
-
The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression
-
Kim, C. et al. The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression. Nat Immunol 9, 1019-1027 (2008).
-
(2008)
Nat Immunol
, vol.9
, pp. 1019-1027
-
-
Kim, C.1
-
34
-
-
0033564341
-
P38 alpha mitogenactivated protein kinase is activated by CD28-mediated signaling and is required for IL-4 production by human CD41CD45RO1 T cells and Th2 effector cells
-
Schafer, P. H., Wadsworth, S. A., Wang, L. & Siekierka, J. J. p38 alpha mitogenactivated protein kinase is activated by CD28-mediated signaling and is required for IL-4 production by human CD41CD45RO1 T cells and Th2 effector cells. J Immunol 162, 7110-7119 (1999).
-
(1999)
J Immunol
, vol.162
, pp. 7110-7119
-
-
Schafer, P.H.1
Wadsworth, S.A.2
Wang, L.3
Siekierka, J.J.4
-
35
-
-
77955059513
-
Mechanisms and functions of p38 MAPK signalling
-
Cuadrado, A. & Nebreda, A. R. Mechanisms and functions of p38 MAPK signalling. Biochem J 429, 403-417 (2010).
-
(2010)
Biochem J
, vol.429
, pp. 403-417
-
-
Cuadrado, A.1
Nebreda, A.R.2
-
36
-
-
0036096284
-
Role of mitogen-activated protein kinases in inducible nitric oxide synthase and TNFalpha expression in human fetal astrocytes
-
Hua, L. L. et al. Role of mitogen-activated protein kinases in inducible nitric oxide synthase and TNFalpha expression in human fetal astrocytes. J Neuroimmunol 126, 180-189 (2002).
-
(2002)
J Neuroimmunol
, vol.126
, pp. 180-189
-
-
Hua, L.L.1
-
37
-
-
0033911179
-
P38 map kinase regulates TNF-alpha production in human astrocytes and microglia by multiple mechanisms
-
Lee, Y. B., Schrader, J. W. & Kim, S. U. p38 map kinase regulates TNF-alpha production in human astrocytes and microglia by multiple mechanisms. Cytokine 12, 874-880 (2000).
-
(2000)
Cytokine
, vol.12
, pp. 874-880
-
-
Lee, Y.B.1
Schrader, J.W.2
Kim, S.U.3
-
38
-
-
78649348355
-
Spinal injection of TNF-alpha-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1
-
Gao, Y. J., Zhang, L. & Ji, R. R. Spinal injection of TNF-alpha-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. Glia 58, 1871-1880 (2010).
-
(2010)
Glia
, vol.58
, pp. 1871-1880
-
-
Gao, Y.J.1
Zhang, L.2
Ji, R.R.3
-
39
-
-
0034660070
-
SICAM-1 and TNF-alpha induce MIP-2 with distinct kinetics in astrocytes and brain microvascular endothelial cells
-
Otto, V. I. et al. sICAM-1 and TNF-alpha induce MIP-2 with distinct kinetics in astrocytes and brain microvascular endothelial cells. J Neurosci Res 60, 733-742 (2000).
-
(2000)
J Neurosci Res
, vol.60
, pp. 733-742
-
-
Otto, V.I.1
-
40
-
-
40949132860
-
Activation of p38 MAPK induced peroxynitrite generation in LPS plus IFN-gamma-stimulated rat primary astrocytes via activation of iNOS and NADPH oxidase
-
Yoo, B. K. et al. Activation of p38 MAPK induced peroxynitrite generation in LPS plus IFN-gamma-stimulated rat primary astrocytes via activation of iNOS and NADPH oxidase. Neurochem Int 52, 1188-1197 (2008).
-
(2008)
Neurochem Int
, vol.52
, pp. 1188-1197
-
-
Yoo, B.K.1
-
41
-
-
0032032424
-
Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
-
Bhat, N. R., Zhang, P., Lee, J. C. & Hogan, E. L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. J Neurosci 18, 1633-1641 (1998).
-
(1998)
J Neurosci
, vol.18
, pp. 1633-1641
-
-
Bhat, N.R.1
Zhang, P.2
Lee, J.C.3
Hogan, E.L.4
-
42
-
-
0042673986
-
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult
-
Piao, C. S., Kim, J. B., Han, P. L. & Lee, J. K. Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult. J Neurosci Res 73, 537-544 (2003).
-
(2003)
J Neurosci Res
, vol.73
, pp. 537-544
-
-
Piao, C.S.1
Kim, J.B.2
Han, P.L.3
Lee, J.K.4
-
43
-
-
0035895803
-
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia
-
Legos, J. J. et al. SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia. Brain Res 892, 70-77 (2001).
-
(2001)
Brain Res
, vol.892
, pp. 70-77
-
-
Legos, J.J.1
-
44
-
-
0035142857
-
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia
-
Barone, F. C. et al. SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J Pharmacol Exp Ther 296, 312-321 (2001).
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 312-321
-
-
Barone, F.C.1
-
45
-
-
10044261073
-
P38alphamitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload
-
Nishida, K. et al. p38alphamitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol Cell Biol 24, 10611-10620 (2004).
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10611-10620
-
-
Nishida, K.1
-
46
-
-
35548932872
-
A global doublefluorescent Cre reporter mouse
-
Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007).
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
47
-
-
53949093338
-
Culture of postnatal mesencephalic dopamine neurons on an astrocyte monolayer
-
Unit 3 21
-
Fasano, C., Thibault, D. & Trudeau, L. E. Culture of postnatal mesencephalic dopamine neurons on an astrocyte monolayer. Curr Protoc Neurosci Chapter 3, Unit 3 21 (2008).
-
(2008)
Curr Protoc Neurosci Chapter
, vol.3
-
-
Fasano, C.1
Thibault, D.2
Trudeau, L.E.3
-
48
-
-
28844446890
-
Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes
-
Hamby, M. E., Uliasz, T. F., Hewett, S. J. & Hewett, J. A. Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes. J Neurosci Methods 150, 128-137 (2006).
-
(2006)
J Neurosci Methods
, vol.150
, pp. 128-137
-
-
Hamby, M.E.1
Uliasz, T.F.2
Hewett, S.J.3
Hewett, J.A.4
-
49
-
-
67650556403
-
Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia
-
Gubern, C. et al. Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia. BMC Mol Biol 10, 57 (2009).
-
(2009)
BMC Mol Biol
, vol.10
, pp. 57
-
-
Gubern, C.1
-
50
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) Method
-
Livak, K. J. & Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) Method. Methods 25, 402-408 (2001).
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
51
-
-
0033568608
-
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
-
Winzen, R. et al. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 18, 4969-4980 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 4969-4980
-
-
Winzen, R.1
-
52
-
-
0028846219
-
Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response
-
Cao, C., Matsumura, K., Yamagata, K. & Watanabe, Y. Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response. Brain Res 697, 187-196 (1995).
-
(1995)
Brain Res
, vol.697
, pp. 187-196
-
-
Cao, C.1
Matsumura, K.2
Yamagata, K.3
Watanabe, Y.4
-
53
-
-
0028283232
-
Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse
-
Steffen, B. J., Butcher, E. C. & Engelhardt, B. Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. Am J Pathol 145, 189-201 (1994).
-
(1994)
Am J Pathol
, vol.145
, pp. 189-201
-
-
Steffen, B.J.1
Butcher, E.C.2
Engelhardt, B.3
-
54
-
-
0034610981
-
Deficiency of the stress kinase p38alpha results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzymedeficient embryonic stem cells
-
Allen, M. et al. Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzymedeficient embryonic stem cells. J Exp Med 191, 859-870 (2000).
-
(2000)
J Exp Med
, vol.191
, pp. 859-870
-
-
Allen, M.1
-
55
-
-
0034641614
-
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis
-
Mudgett, J. S. et al. Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci U S A 97, 10454-10459 (2000).
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10454-10459
-
-
Mudgett, J.S.1
-
56
-
-
77955406469
-
Rhizoma coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway
-
Remppis, A. et al. Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators Inflamm 2010, 194896 (2010).
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 194896
-
-
Remppis, A.1
-
57
-
-
27744596001
-
Akt/protein kinase B activation by adenovirus vectors contributes to NFkappaB-dependent CXCL10 expression
-
Liu, Q. et al. Akt/protein kinase B activation by adenovirus vectors contributes to NFkappaB-dependent CXCL10 expression. J Virol 79, 14507-14515 (2005).
-
(2005)
J Virol
, vol.79
, pp. 14507-14515
-
-
Liu, Q.1
-
58
-
-
0025343895
-
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
-
Libermann, T. A. & Baltimore, D. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol Cell Biol 10, 2327-2334 (1990).
-
(1990)
Mol Cell Biol
, vol.10
, pp. 2327-2334
-
-
Libermann, T.A.1
Baltimore, D.2
-
59
-
-
68049083543
-
Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected]
-
Thompson, W. L. & Van Eldik, L. J. Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected]. Brain Res 1287, 47-57 (2009).
-
(2009)
Brain Res
, vol.1287
, pp. 47-57
-
-
Thompson, W.L.1
Van Eldik, L.J.2
-
60
-
-
0036143654
-
P38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment
-
Saccani, S., Pantano, S. & Natoli, G. p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 3, 69-75 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 69-75
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
61
-
-
46749125681
-
Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway
-
Lin, S. T. et al. Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway. Mol Cell Biochem 315, 41-49 (2008).
-
(2008)
Mol Cell Biochem
, vol.315
, pp. 41-49
-
-
Lin, S.T.1
-
62
-
-
0035348410
-
Induction of RANTES chemokine expression in human astrocytic cells is dependent upon activation of NF-kappaB transcription factor
-
Li, Q. Q., Bever, C. T., Burt, D. R., Judge, S. I. & Trisler, G. D. Induction of RANTES chemokine expression in human astrocytic cells is dependent upon activation of NF-kappaB transcription factor. Int J Mol Med 7, 527-533 (2001).
-
(2001)
Int J Mol Med
, vol.7
, pp. 527-533
-
-
Li, Q.Q.1
Bever, C.T.2
Burt, D.R.3
Judge, S.I.4
Trisler, G.D.5
-
63
-
-
0037332421
-
Interleukin-1beta stimulates macrophage inflammatory protein-1alpha and -1beta expression in human neuronal cells (NT2-N)
-
Guo, C. J. et al. Interleukin-1beta stimulates macrophage inflammatory protein-1alpha and -1beta expression in human neuronal cells (NT2-N). J Neurochem 84, 997-1005 (2003).
-
(2003)
J Neurochem
, vol.84
, pp. 997-1005
-
-
Guo, C.J.1
-
64
-
-
79955936789
-
Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-kappaB and JNK activation in intestinal epithelial cells
-
Song, Y. A. et al. Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-kappaB and JNK activation in intestinal epithelial cells. Inflamm Res 60, 493-500 (2010).
-
(2010)
Inflamm Res
, vol.60
, pp. 493-500
-
-
Song, Y.A.1
-
65
-
-
37349081594
-
Antagonistic control of cell fates by JNK and p38-MAPK signaling
-
Wada, T. et al. Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death Differ 15, 89-93 (2008).
-
(2008)
Cell Death Differ
, vol.15
, pp. 89-93
-
-
Wada, T.1
-
66
-
-
41549160315
-
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
-
Junttila, M. R., Li, S. P. & Westermarck, J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 22, 954-965 (2008).
-
(2008)
FASEB J
, vol.22
, pp. 954-965
-
-
Junttila, M.R.1
Li, S.P.2
Westermarck, J.3
-
67
-
-
67749117934
-
Signal integration by JNK and p38 MAPK pathways in cancer development
-
Wagner, E. F. & Nebreda, A. R. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer 9, 537-549 (2009).
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
68
-
-
45549094532
-
Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun. Pathway
-
Hoffmann, E. et al. Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun. pathway. J Biol Chem 283, 12120-12128 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 12120-12128
-
-
Hoffmann, E.1
-
69
-
-
1642483742
-
2-terminal kinase activation in human neutrophils: Role of phosphatidylinositol 3-Kinase and Syk-mediated pathways
-
2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathways. J Biol Chem 279, 10883-10891 (2004).
-
(2004)
J Biol Chem
, vol.279
, pp. 10883-10891
-
-
Arndt, P.G.1
Suzuki, N.2
Avdi, N.J.3
Malcolm, K.C.4
Worthen, G.S.5
-
70
-
-
0344643419
-
TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway
-
Funakoshi-Tago, M., Tago, K., Sonoda, Y., Tominaga, S. & Kasahara, T. TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway. Eur J Biochem 270, 1257-1268 (2003).
-
(2003)
Eur J Biochem
, vol.270
, pp. 1257-1268
-
-
Funakoshi-Tago, M.1
Tago, K.2
Sonoda, Y.3
Tominaga, S.4
Kasahara, T.5
-
71
-
-
0032854964
-
Adenovirus-mediated overexpression of c-Jun. and c-Fos induces intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human endothelial cells
-
Wang, N. et al. Adenovirus-mediated overexpression of c-Jun. and c-Fos induces intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human endothelial cells. Arterioscler Thromb Vasc Biol 19, 2078-2084 (1999).
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2078-2084
-
-
Wang, N.1
-
72
-
-
46149104370
-
C-Jun. Controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene
-
Wolter, S. et al. c-Jun. controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol 28, 4407-4423 (2008).
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4407-4423
-
-
Wolter, S.1
-
73
-
-
0037223402
-
P38 Mitogen-activated protein kinase-dependent and - Independent signaling of mRNA stability of AU-rich element-containing transcripts
-
Frevel, M. A. et al. p38 Mitogen-activated protein kinase-dependent and - independent signaling of mRNA stability of AU-rich element-containing transcripts. Mol Cell Biol 23, 425-436 (2003).
-
(2003)
Mol Cell Biol
, vol.23
, pp. 425-436
-
-
Frevel, M.A.1
-
74
-
-
3142546235
-
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathwaymediated mRNA stabilisation
-
Dean, J. L., Sully, G., Clark, A. R. & Saklatvala, J. The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathwaymediated mRNA stabilisation. Cell Signal 16, 1113-1121 (2004).
-
(2004)
Cell Signal
, vol.16
, pp. 1113-1121
-
-
Dean, J.L.1
Sully, G.2
Clark, A.R.3
Saklatvala, J.4
-
75
-
-
0141960214
-
P38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation
-
Dean, J. L., Sarsfield, S. J., Tsounakou, E. & Saklatvala, J. p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation. J Biol Chem 278, 39470-39476 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 39470-39476
-
-
Dean, J.L.1
Sarsfield, S.J.2
Tsounakou, E.3
Saklatvala, J.4
-
76
-
-
0344586094
-
Analysis of the mechanism regulating the stability of rat macrophage inflammatory protein-2 mRNA in RBL-2H3 cells
-
Numahata, K. et al. Analysis of the mechanism regulating the stability of rat macrophage inflammatory protein-2 mRNA in RBL-2H3 cells. J Cell Biochem 90, 976-986 (2003).
-
(2003)
J Cell Biochem
, vol.90
, pp. 976-986
-
-
Numahata, K.1
-
77
-
-
0036479125
-
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different posttranscriptional levels
-
Neininger, A. et al. MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different posttranscriptional levels. J Biol Chem 277, 3065-3068 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 3065-3068
-
-
Neininger, A.1
-
78
-
-
0034816062
-
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
-
Mahtani, K. R. et al. Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol Cell Biol 21, 6461-6469 (2001).
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6461-6469
-
-
Mahtani, K.R.1
-
79
-
-
33845807361
-
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK
-
Ronkina, N. et al. The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol Cell Biol 27, 170-181 (2007).
-
(2007)
Mol Cell Biol
, vol.27
, pp. 170-181
-
-
Ronkina, N.1
-
80
-
-
33747632142
-
MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease
-
Culbert, A. A. et al. MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease. J Biol Chem 281, 23658-23667 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 23658-23667
-
-
Culbert, A.A.1
-
81
-
-
33645101274
-
MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA
-
Sun, D. & Ding, A. MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA. Nat Immunol 7, 375-381 (2006).
-
(2006)
Nat Immunol
, vol.7
, pp. 375-381
-
-
Sun, D.1
Ding, A.2
-
82
-
-
77950521720
-
Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion
-
Pineau, I., Sun, L., Bastien, D. & Lacroix, S. Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion. Brain Behav Immun 24, 540-553 (2010).
-
(2010)
Brain Behav Immun
, vol.24
, pp. 540-553
-
-
Pineau, I.1
Sun, L.2
Bastien, D.3
Lacroix, S.4
-
83
-
-
78650250592
-
Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFkappaB signaling, MAPK, and Jak1/Stat1 pathways
-
Gorina, R. et al. Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFkappaB signaling, MAPK, and Jak1/Stat1 pathways. Glia 59, 242-255 (2011).
-
(2011)
Glia
, vol.59
, pp. 242-255
-
-
Gorina, R.1
-
85
-
-
0345690207
-
Cross-talk in the innate immune system: Neutrophils instruct recruitment and activation of dendritic cells during microbial infection
-
Bennouna, S., Bliss, S. K., Curiel, T. J. & Denkers, E. Y. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J Immunol 171, 6052-6058 (2003).
-
(2003)
J Immunol
, vol.171
, pp. 6052-6058
-
-
Bennouna, S.1
Bliss, S.K.2
Curiel, T.J.3
Denkers, E.Y.4
-
86
-
-
0032925898
-
Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1alpha attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis
-
Diab, A. et al. Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1alpha attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis. Infect Immun 67, 2590-2601 (1999).
-
(1999)
Infect Immun
, vol.67
, pp. 2590-2601
-
-
Diab, A.1
-
87
-
-
1542298238
-
Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production
-
Kim, S. H., Smith, C. J. & Van Eldik, L. J. Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production. Neurobiol Aging 25, 431-439 (2004).
-
(2004)
Neurobiol Aging
, vol.25
, pp. 431-439
-
-
Kim, S.H.1
Smith, C.J.2
Van Eldik, L.J.3
-
88
-
-
1942486751
-
Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat
-
D'Aversa, T. G., Yu, K. O. & Berman, J. W. Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat. J Neurovirol 10, 86-97 (2004).
-
(2004)
J Neurovirol
, vol.10
, pp. 86-97
-
-
D'Aversa, T.G.1
Yu, K.O.2
Berman, J.W.3
-
89
-
-
0032733230
-
Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis
-
Persidsky, Y. et al. Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. Am J Pathol 155, 1599-1611 (1999).
-
(1999)
Am J Pathol
, vol.155
, pp. 1599-1611
-
-
Persidsky, Y.1
-
90
-
-
0035983756
-
TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion
-
Ciesielski, C. J., Andreakos, E., Foxwell, B. M. & Feldmann, M. TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur J Immunol 32, 2037-2045 (2002).
-
(2002)
Eur J Immunol
, vol.32
, pp. 2037-2045
-
-
Ciesielski, C.J.1
Andreakos, E.2
Foxwell, B.M.3
Feldmann, M.4
-
91
-
-
0027999958
-
A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions
-
Jones, D. A., McIntire, L. V., Smith, C. W. & Picker, L. J. A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions. J Clin Invest 94, 2443-2450 (1994).
-
(1994)
J Clin Invest
, vol.94
, pp. 2443-2450
-
-
Jones, D.A.1
McIntire, L.V.2
Smith, C.W.3
Picker, L.J.4
-
92
-
-
0025301596
-
Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system
-
Sobel, R. A., Mitchell, M. E. & Fondren, G. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. Am J Pathol 136, 1309-1316 (1990).
-
(1990)
Am J Pathol
, vol.136
, pp. 1309-1316
-
-
Sobel, R.A.1
Mitchell, M.E.2
Fondren, G.3
-
93
-
-
15544370150
-
Adult neurogenesis: From precursors to network and physiology
-
Abrous, D. N., Koehl, M. & Le Moal, M. Adult neurogenesis: from precursors to network and physiology. Physiol Rev 85, 523-569 (2005).
-
(2005)
Physiol Rev
, vol.85
, pp. 523-569
-
-
Abrous, D.N.1
Koehl, M.2
Le Moal, M.3
-
94
-
-
7044233126
-
GFAPexpressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain
-
Garcia, A. D., Doan, N. B., Imura, T., Bush, T. G. & Sofroniew, M. V. GFAPexpressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci 7, 1233-1241 (2004).
-
(2004)
Nat Neurosci
, vol.7
, pp. 1233-1241
-
-
Garcia, A.D.1
Doan, N.B.2
Imura, T.3
Bush, T.G.4
Sofroniew, M.V.5
-
95
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch, F., Caille, I., Lim, D. A., Garcia-Verdugo, J. M. & Alvarez-Buylla, A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97, 703-716 (1999).
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
|