Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1

GLIA

Volumn 58, Issue 15, 2010, Pages 1871-1880

  Gao, Yong Jing ^a   Zhang, Ling ^a   Ji, Ru Rong ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Astrocytes; Central sensitization; JNK; MCP 1; TNF

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; ENZYME ACTIVATION; MICROGLIA; MOUSE; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SPINAL CORD;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; ASTROCYTES; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CEREBRAL CORTEX; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; PAIN THRESHOLD; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RNA, SMALL INTERFERING; SPINAL CORD; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78649348355     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21056     Document Type: Article

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