Probing the dynamic regulation of peripheral membrane proteins using hydrogen deuterium exchange-MS (HDX-MS)

Biochemical Society Transactions

Volumn 43, Issue , 2015, Pages 773-786

  Vadas, Oscar ^a   Burke, John E ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF VICTORIA   (Canada)

Author keywords

Catalytic subunit of PI3K (PIK3CA); Hydrogen deuterium exchange mass spectrometry (HDX MS); Membrane proteins; P85 regulatory subunit of class I PI3K (PIK3R1); Phosphoinositide 3 kinases (PI3Ks); Protein dynamics

Indexed keywords

G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN TYROSINE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE;

ARTICLE; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVATION; ENZYME REGULATION; GENE MUTATION; HUMAN; MASS SPECTROMETRY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; AWARDS AND PRIZES; BIOCHEMISTRY; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; GREAT BRITAIN; HEALTH CARE ORGANIZATION; HISTORY; METABOLISM; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN TRANSPORT;

ANIMALS; ANNIVERSARIES AND SPECIAL EVENTS; AWARDS AND PRIZES; BIOCHEMISTRY; CELL MEMBRANE; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; DEUTERIUM EXCHANGE MEASUREMENT; GREAT BRITAIN; HUMANS; MASS SPECTROMETRY; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SOCIETIES, SCIENTIFIC;

EID: 84947294620     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20150065     Document Type: Article

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