Structural insights into phosphoinositide 3-kinase catalysis and signalling

Nature

Volumn 402, Issue 6759, 1999, Pages 313-320

  Walker, Edward H ^a   Perisic, Olga ^a   Ried, Christian ^a   Stephens, Len ^b   Williams, Roger L ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHOSPHOINOSITIDE; RAS PROTEIN; TRIPHOSPHOINOSITIDE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; INSECT; INTRACELLULAR MEMBRANE; NONHUMAN; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SECOND MESSENGER; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CATALYTIC DOMAIN; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RAP1 GTP-BINDING PROTEINS; RAS PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SWINE;

EID: 0033581886     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/46319     Document Type: Article

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