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Volumn 87, Issue , 2015, Pages 366-372

New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death

Author keywords

24(S) Hydroxycholesterol; Cell death; Cholesterolhomeostasis; CYP46A1; Freeradicals; Neurodegenerativedisease

Indexed keywords

24 HYDROXYCHOLESTEROL; AMYLOID PRECURSOR PROTEIN; CASPASE 8; CHOLESTEROL DERIVATIVE; LIVER X RECEPTOR; OXYSTEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; ORPHAN NUCLEAR RECEPTOR;

EID: 84944324351     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.06.036     Document Type: Review
Times cited : (32)

References (94)
  • 1
  • 2
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelin is made locally, not imported into brain
    • H. Jurevics, and P. Morell Cholesterol for synthesis of myelin is made locally, not imported into brain J. Neurochem. 64 1995 895 901
    • (1995) J. Neurochem. , vol.64 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 3
    • 3543104951 scopus 로고    scopus 로고
    • Thematic review series: brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
    • J.M. Dietschy, and S.D. Turley Thematic review series: brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal J. Lipid Res. 45 2004 1375 1397
    • (2004) J. Lipid Res. , vol.45 , pp. 1375-1397
    • Dietschy, J.M.1    Turley, S.D.2
  • 4
    • 79960459422 scopus 로고    scopus 로고
    • Cholesterol metabolism in neurons and astrocytes
    • F.W. Pfrieger, and N. Ungerer Cholesterol metabolism in neurons and astrocytes Prog. Lipid Res. 50 2011 357 371
    • (2011) Prog. Lipid Res. , vol.50 , pp. 357-371
    • Pfrieger, F.W.1    Ungerer, N.2
  • 7
  • 8
    • 0030729021 scopus 로고    scopus 로고
    • Importance of a novel oxidative mechanism for elimination of brain cholesterol
    • I. Björkhem, D. Lütjohann, O. Breuer, A. Sakinis, and A. Wennmalm Importance of a novel oxidative mechanism for elimination of brain cholesterol J. Biol. Chem. 48 1997 30178 30184
    • (1997) J. Biol. Chem. , vol.48 , pp. 30178-30184
    • Björkhem, I.1    Lütjohann, D.2    Breuer, O.3    Sakinis, A.4    Wennmalm, A.5
  • 9
    • 0032892176 scopus 로고    scopus 로고
    • Removal of cholesterol from extrahepatic sources by oxidative mechanisms
    • I. Björkhem, U. Diczfalusy, and D. Lütjohann Removal of cholesterol from extrahepatic sources by oxidative mechanisms Curr. Opin. Lipidol. 10 1999 161 165
    • (1999) Curr. Opin. Lipidol. , vol.10 , pp. 161-165
    • Björkhem, I.1    Diczfalusy, U.2    Lütjohann, D.3
  • 10
    • 35548981361 scopus 로고    scopus 로고
    • Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier
    • S. Ohtsuki, S. Ito, A. Matsuda, S. Hori, T. Abe, and T. Terasaki Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier J. Neurochem. 103 2007 1430 1438
    • (2007) J. Neurochem. , vol.103 , pp. 1430-1438
    • Ohtsuki, S.1    Ito, S.2    Matsuda, A.3    Hori, S.4    Abe, T.5    Terasaki, T.6
  • 11
    • 0038265008 scopus 로고    scopus 로고
    • Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover
    • E.G. Lund, C. Xie, T. Kotti, S.D. Turley, J.M. Dietschy, and D.W. Russell Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover J. Biol. Chem. 278 2003 22980 22988
    • (2003) J. Biol. Chem. , vol.278 , pp. 22980-22988
    • Lund, E.G.1    Xie, C.2    Kotti, T.3    Turley, S.D.4    Dietschy, J.M.5    Russell, D.W.6
  • 12
    • 0029835410 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
    • D. Lütjohann, O. Breuer, G. Ahlborg, I. Nennesmo, A. Sidén, U. Diczfalusy, and I. Björkhem Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation Proc. Natl. Acad. Sci. USA 93 1996 9799 9804
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9799-9804
    • Lütjohann, D.1    Breuer, O.2    Ahlborg, G.3    Nennesmo, I.4    Sidén, A.5    Diczfalusy, U.6    Björkhem, I.7
  • 13
    • 34249848111 scopus 로고    scopus 로고
    • Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig
    • A. Radhakrishnan, Y. Ikeda, H.J. Kwon, M.S. Brown, and J.L. Goldstein Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig Proc. Natl. Acad. Sci. USA 104 2007 6511 6518
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6511-6518
    • Radhakrishnan, A.1    Ikeda, Y.2    Kwon, H.J.3    Brown, M.S.4    Goldstein, J.L.5
  • 15
    • 84898831894 scopus 로고    scopus 로고
    • Effects of oxysterols on the blood-brain barrier: implications for Alzheimer's disease
    • F. Gosselet, J. Saint-Pol, and L. Fenart Effects of oxysterols on the blood-brain barrier: implications for Alzheimer's disease Biochem. Biophys. Res. Commun. 446 2014 687 691
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 687-691
    • Gosselet, F.1    Saint-Pol, J.2    Fenart, L.3
  • 20
    • 80053557887 scopus 로고    scopus 로고
    • Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study
    • G. Zuliani, M.P. Donnorso, C. Bosi, A. Passaro, N.E. Dalla, A. Zurlo, F. Bonetti, A.F. Mozzi, and C. Cortese Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study BMC Neurol. 11 2011 121
    • (2011) BMC Neurol. , vol.11 , pp. 121
    • Zuliani, G.1    Donnorso, M.P.2    Bosi, C.3    Passaro, A.4    Dalla, N.E.5    Zurlo, A.6    Bonetti, F.7    Mozzi, A.F.8    Cortese, C.9
  • 21
    • 34548634369 scopus 로고    scopus 로고
    • Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxychholesterol in patients with cognitive disorders
    • M. Shafaati, A. Solomon, M. Kivipelto, I. Björkhem, and V. Leoni Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxychholesterol in patients with cognitive disorders Neurosci. Lett. 425 2007 78 82
    • (2007) Neurosci. Lett. , vol.425 , pp. 78-82
    • Shafaati, M.1    Solomon, A.2    Kivipelto, M.3    Björkhem, I.4    Leoni, V.5
  • 24
    • 84885120728 scopus 로고    scopus 로고
    • Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease
    • I. Björkhem, A. Lövgren-Sandblom, V. Leoni, S. Meaney, L. Brodin, L. Salveson, and et al. Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease Neurosci. Lett. 555 2013 102 105
    • (2013) Neurosci. Lett. , vol.555 , pp. 102-105
    • Björkhem, I.1    Lövgren-Sandblom, A.2    Leoni, V.3    Meaney, S.4    Brodin, L.5    Salveson, L.6
  • 25
    • 58849085001 scopus 로고    scopus 로고
    • Different patterns of oxidized lipid products in plasma and urine of dengue fever, stroke, and Parkinson's disease patients: cautions in the use of biomarkers of oxidative stress
    • C.Y. Lee, R.C. Seet, S.H. Huang, L.H. Long, and B. Halliwell Different patterns of oxidized lipid products in plasma and urine of dengue fever, stroke, and Parkinson's disease patients: cautions in the use of biomarkers of oxidative stress Antioxid. Redox Signaling 11 2009 407 420
    • (2009) Antioxid. Redox Signaling , vol.11 , pp. 407-420
    • Lee, C.Y.1    Seet, R.C.2    Huang, S.H.3    Long, L.H.4    Halliwell, B.5
  • 26
    • 84876731616 scopus 로고    scopus 로고
    • Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression
    • V. Leoni, J.D. Long, J.A. Mills, S. Di Donato, and J.S. Paulsen Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression Neurobiol. Dis. 55 2013 37 43
    • (2013) Neurobiol. Dis. , vol.55 , pp. 37-43
    • Leoni, V.1    Long, J.D.2    Mills, J.A.3    Di Donato, S.4    Paulsen, J.S.5
  • 27
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • V. Leoni, and C. Caccia Oxysterols as biomarkers in neurodegenerative diseases Chem. Phys. Lipids 164 2011 515 524
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 28
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier, oxysterols as cholesterol transporters and metabolic modulators in the brain
    • I. Björkhem Crossing the barrier, oxysterols as cholesterol transporters and metabolic modulators in the brain J. Intern. Med. 260 2006 493 508
    • (2006) J. Intern. Med. , vol.260 , pp. 493-508
    • Björkhem, I.1
  • 30
    • 65649083410 scopus 로고    scopus 로고
    • Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry
    • B. Sottero, P. Gamba, S. Gargiulo, S. Leonarduzzi, and G. Poli Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry Curr. Med. Chem. 16 2009 685 705
    • (2009) Curr. Med. Chem. , vol.16 , pp. 685-705
    • Sottero, B.1    Gamba, P.2    Gargiulo, S.3    Leonarduzzi, S.4    Poli, G.5
  • 31
    • 80051471752 scopus 로고    scopus 로고
    • Pathways of cholesterol oxidation via non-enzymatic mechanisms
    • L. Iuliano Pathways of cholesterol oxidation via non-enzymatic mechanisms Chem. Phys. Lipids 164 2011 457 458
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 457-458
    • Iuliano, L.1
  • 32
    • 84878798159 scopus 로고    scopus 로고
    • Oxysterols in the pathogenesis of major chronic diseases
    • G. Poli, F. Biasi, and G. Leonarduzzi Oxysterols in the pathogenesis of major chronic diseases Redox Biol 1 2013 125 130
    • (2013) Redox Biol , vol.1 , pp. 125-130
    • Poli, G.1    Biasi, F.2    Leonarduzzi, G.3
  • 33
    • 67650729358 scopus 로고    scopus 로고
    • Lipid peroxidation: physiological levels and dual biological effects
    • E. Niki Lipid peroxidation: physiological levels and dual biological effects Free Radic. Biol. Med. 47 2009 469 484
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 469-484
    • Niki, E.1
  • 34
    • 14844304305 scopus 로고    scopus 로고
    • Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide
    • T.J. Nelson, and D.L. Alkon Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide J. Biol. Chem. 280 2005 7377 7387
    • (2005) J. Biol. Chem. , vol.280 , pp. 7377-7387
    • Nelson, T.J.1    Alkon, D.L.2
  • 35
    • 52949150827 scopus 로고    scopus 로고
    • Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis
    • A. Vejux, L. Malvitte, and G. Lizard Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis Braz. J. Med. Biol. Res. 41 2008 545 556
    • (2008) Braz. J. Med. Biol. Res. , vol.41 , pp. 545-556
    • Vejux, A.1    Malvitte, L.2    Lizard, G.3
  • 36
    • 84898827016 scopus 로고    scopus 로고
    • 7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: difference between cellular and plasma lipid peroxidation
    • Y. Saito, and N. Noguchi 7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: difference between cellular and plasma lipid peroxidation Biochem. Biophys. Res. Commun. 446 2014 741 744
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 741-744
    • Saito, Y.1    Noguchi, N.2
  • 37
    • 84874111592 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol
    • T. Mitić, R. Andrew, B.R. Walker, and P.W. Hadoke 11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol Biochimie 95 2013 548 555
    • (2013) Biochimie , vol.95 , pp. 548-555
    • Mitić, T.1    Andrew, R.2    Walker, B.R.3    Hadoke, P.W.4
  • 38
    • 0027298061 scopus 로고
    • Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
    • J. Poirier, A. Baccichet, D. Dea, and S. Gauthier Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats Neuroscience 55 1993 81 90
    • (1993) Neuroscience , vol.55 , pp. 81-90
    • Poirier, J.1    Baccichet, A.2    Dea, D.3    Gauthier, S.4
  • 39
    • 41549141257 scopus 로고    scopus 로고
    • Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain
    • D.M. Ramirez, S. Andersson, and D.W. Russell Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain J. Comp. Neurol. 507 2008 1676 1693
    • (2008) J. Comp. Neurol. , vol.507 , pp. 1676-1693
    • Ramirez, D.M.1    Andersson, S.2    Russell, D.W.3
  • 40
    • 0035856407 scopus 로고    scopus 로고
    • On the turnover of brain cholesterol in patients with Alzheimer's disease: abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells
    • N. Bogdanovic, L. Bretillon, E.G. Lund, U. Diczfalusy, L. Lannfelt, B. Winblad, D.W. Russell, and I. Björkhem On the turnover of brain cholesterol in patients with Alzheimer's disease: abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells Neurosci. Lett. 314 2001 45 48
    • (2001) Neurosci. Lett. , vol.314 , pp. 45-48
    • Bogdanovic, N.1    Bretillon, L.2    Lund, E.G.3    Diczfalusy, U.4    Lannfelt, L.5    Winblad, B.6    Russell, D.W.7    Björkhem, I.8
  • 43
    • 40849118468 scopus 로고    scopus 로고
    • Peripheral neuropathy and neurosteroid formation in the central nervous system
    • C. Patte-Mensah, and A.G. Mensah-Nyagan Peripheral neuropathy and neurosteroid formation in the central nervous system Brain Res. Rev. 57 2008 454 459
    • (2008) Brain Res. Rev. , vol.57 , pp. 454-459
    • Patte-Mensah, C.1    Mensah-Nyagan, A.G.2
  • 44
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: endogenous role in the human brain and therapeutic potentials
    • S.R. Doodipala Neurosteroids: endogenous role in the human brain and therapeutic potentials Prog. Brain Res. 186 2010 113 137
    • (2010) Prog. Brain Res. , vol.186 , pp. 113-137
    • Doodipala, S.R.1
  • 46
    • 0033305132 scopus 로고    scopus 로고
    • Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain
    • I.H. Zwain, and S.S. Yen Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain Endocrinology 140 1999 3843 3852
    • (1999) Endocrinology , vol.140 , pp. 3843-3852
    • Zwain, I.H.1    Yen, S.S.2
  • 49
    • 74149083432 scopus 로고    scopus 로고
    • Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
    • E. Hudry, D. Van Dam, W. Kulik, P.P. De Deyn, F.S. Stet, O. Ahouansou, A. Benraiss, A. Delacourte, P. Bougnères, P. Aubourg, and N. Cartier Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease Mol. Ther. 18 2010 44 53
    • (2010) Mol. Ther. , vol.18 , pp. 44-53
    • Hudry, E.1    Van Dam, D.2    Kulik, W.3    De Deyn, P.P.4    Stet, F.S.5    Ahouansou, O.6    Benraiss, A.7    Delacourte, A.8    Bougnères, P.9    Aubourg, P.10    Cartier, N.11
  • 50
    • 62549132123 scopus 로고    scopus 로고
    • Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan
    • R.W. Halford, and D.W. Russell Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan Proc. Natl. Acad. Sci. USA 106 2009 3502 3506
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3502-3506
    • Halford, R.W.1    Russell, D.W.2
  • 51
    • 77957791628 scopus 로고    scopus 로고
    • Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain
    • N. Mast, C. Charvet, I.A. Pikuleva, and C.D. Stout Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain J. Biol. Chem. 285 2010 31783 31795
    • (2010) J. Biol. Chem. , vol.285 , pp. 31783-31795
    • Mast, N.1    Charvet, C.2    Pikuleva, I.A.3    Stout, C.D.4
  • 53
    • 84898808313 scopus 로고    scopus 로고
    • In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina
    • C. Fourgeux, L. Martine, N. Acar, A.M. Bron, C.P. Creuzot-Garcher, and L. Bretillon In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina Biochem. Biophys. Res. Commun. 446 2014 775 781
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 775-781
    • Fourgeux, C.1    Martine, L.2    Acar, N.3    Bron, A.M.4    Creuzot-Garcher, C.P.5    Bretillon, L.6
  • 54
    • 84870920138 scopus 로고    scopus 로고
    • Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal
    • Y. Huang, W. Li, and A.N. Kong Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal Cell Biosci 2 2012 40
    • (2012) Cell Biosci , vol.2 , pp. 40
    • Huang, Y.1    Li, W.2    Kong, A.N.3
  • 55
    • 33744940306 scopus 로고    scopus 로고
    • Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms
    • Z.H. Chen, Y. Yoshida, Y. Saito, A. Sekine, N. Noguchi, and E. Niki Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms J. Biol. Chem. 281 2006 14440 14445
    • (2006) J. Biol. Chem. , vol.281 , pp. 14440-14445
    • Chen, Z.H.1    Yoshida, Y.2    Saito, Y.3    Sekine, A.4    Noguchi, N.5    Niki, E.6
  • 56
    • 34547924456 scopus 로고    scopus 로고
    • Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione
    • Y. Saito, K. Nishio, Y. Numakawa, Y. Ogawa, Y. Yoshida, N. Noguchi, and E. Niki Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione J. Neurochem. 102 2007 1625 1634
    • (2007) J. Neurochem. , vol.102 , pp. 1625-1634
    • Saito, Y.1    Nishio, K.2    Numakawa, Y.3    Ogawa, Y.4    Yoshida, Y.5    Noguchi, N.6    Niki, E.7
  • 57
    • 0033386960 scopus 로고    scopus 로고
    • Induction of apoptosis and necrosis in human neuroblastoma cells by cholesterol oxides
    • M.L. Rao, D. Lütjohann, M. Ludwig, and H. Kölsch Induction of apoptosis and necrosis in human neuroblastoma cells by cholesterol oxides Ann. N.Y. Acad. Sci. 893 1999 379 381
    • (1999) Ann. N.Y. Acad. Sci. , vol.893 , pp. 379-381
    • Rao, M.L.1    Lütjohann, D.2    Ludwig, M.3    Kölsch, H.4
  • 58
    • 67349087552 scopus 로고    scopus 로고
    • Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated PC12 cells by suppressing mitochondrial membrane permeability change
    • D.E. Kim, Y.C. Youn, Y.K. Kim, K.M. Hong, and C.S. Lee Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated PC12 cells by suppressing mitochondrial membrane permeability change Neurochem. Res. 34 2009 1433 1442
    • (2009) Neurochem. Res. , vol.34 , pp. 1433-1442
    • Kim, D.E.1    Youn, Y.C.2    Kim, Y.K.3    Hong, K.M.4    Lee, C.S.5
  • 59
    • 78650414582 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways
    • E.R. Jang, and C.S. Lee 7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways Neurochem. Int. 58 2011 52 59
    • (2011) Neurochem. Int. , vol.58 , pp. 52-59
    • Jang, E.R.1    Lee, C.S.2
  • 60
    • 84890826882 scopus 로고    scopus 로고
    • Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death
    • A. Okabe, Y. Urano, S. Itoh, N. Suda, R. Kotani, Y. Nishimura, Y. Saito, and N. Noguchi Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death Redox Biol. 2 2013 28 35
    • (2013) Redox Biol. , vol.2 , pp. 28-35
    • Okabe, A.1    Urano, Y.2    Itoh, S.3    Suda, N.4    Kotani, R.5    Nishimura, Y.6    Saito, Y.7    Noguchi, N.8
  • 62
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 64
    • 0030808462 scopus 로고    scopus 로고
    • Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction
    • S. Estus, H.M. Tucker, C. van Rooyen, S. Wright, E.F. Brigham, M. Wogulis, and R.E. Rydel Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction J. Neurosci. 17 1997 7736 7745
    • (1997) J. Neurosci. , vol.17 , pp. 7736-7745
    • Estus, S.1    Tucker, H.M.2    Van Rooyen, C.3    Wright, S.4    Brigham, E.F.5    Wogulis, M.6    Rydel, R.E.7
  • 65
    • 62149140601 scopus 로고    scopus 로고
    • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells
    • J.R. Prasanthi, A. Huls, S. Thomasson, A. Thompson, E. Schommer, and O. Ghribi Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells Mol. Neurodegener 4 2009 1
    • (2009) Mol. Neurodegener , vol.4 , pp. 1
    • Prasanthi, J.R.1    Huls, A.2    Thomasson, S.3    Thompson, A.4    Schommer, E.5    Ghribi, O.6
  • 67
    • 14844314117 scopus 로고    scopus 로고
    • Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles
    • J. Kim, S. Hamamoto, M. Ravazzola, L. Orci, and R. Schekman Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles J. Biol. Chem. 280 2005 7758 7768
    • (2005) J. Biol. Chem. , vol.280 , pp. 7758-7768
    • Kim, J.1    Hamamoto, S.2    Ravazzola, M.3    Orci, L.4    Schekman, R.5
  • 69
    • 84885165023 scopus 로고    scopus 로고
    • Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking
    • Y. Urano, S. Ochiai, and N. Noguchi Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking FASEB J 27 2013 4305 4315
    • (2013) FASEB J , vol.27 , pp. 4305-4315
    • Urano, Y.1    Ochiai, S.2    Noguchi, N.3
  • 71
    • 84906939555 scopus 로고    scopus 로고
    • Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease
    • E. Hubin, N.A. van Nuland, K. Broersen, and K. Pauwels Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease Cell Mol. Life Sci. 71 2014 3507 3521
    • (2014) Cell Mol. Life Sci. , vol.71 , pp. 3507-3521
    • Hubin, E.1    Van Nuland, N.A.2    Broersen, K.3    Pauwels, K.4
  • 72
    • 84903713725 scopus 로고    scopus 로고
    • Inhibition of amyloid-β aggregation in Alzheimer's disease.
    • Q. Wang, X. Yu, L. Li, and J. Zheng Inhibition of amyloid-β aggregation in Alzheimer's disease. Curr. Pharm. Des 20 2014 1223 1243
    • (2014) Curr. Pharm. Des , vol.20 , pp. 1223-1243
    • Wang, Q.1    Yu, X.2    Li, L.3    Zheng, J.4
  • 75
    • 0037073670 scopus 로고    scopus 로고
    • Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels
    • H. Fukumoto, A. Deng, M.C. Irizarry, M.L. Fitzgerald, and G.W. Rebeck Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels J. Biol. Chem. 277 2002 48508 48513
    • (2002) J. Biol. Chem. , vol.277 , pp. 48508-48513
    • Fukumoto, H.1    Deng, A.2    Irizarry, M.C.3    Fitzgerald, M.L.4    Rebeck, G.W.5
  • 76
    • 46249124246 scopus 로고    scopus 로고
    • Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress
    • P. Ferrera, O. Mercado-Gómez, M. Silva-Aguilar, M. Valverde, and C. Arias Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress Neurochem. Res. 33 2008 1509 1517
    • (2008) Neurochem. Res. , vol.33 , pp. 1509-1517
    • Ferrera, P.1    Mercado-Gómez, O.2    Silva-Aguilar, M.3    Valverde, M.4    Arias, C.5
  • 77
    • 38949085846 scopus 로고    scopus 로고
    • Complex of amyloid beta peptides with 24-hydroxycholesterol and its effect on hemicholinium-3 sensitive carriers
    • Z. Kristofiková, V. Kopecký Jr, K. Hofbauerová, P. Hovorková, and D. Rípová Complex of amyloid beta peptides with 24-hydroxycholesterol and its effect on hemicholinium-3 sensitive carriers Neurochem. Res. 33 2008 412 421
    • (2008) Neurochem. Res. , vol.33 , pp. 412-421
    • Kristofiková, Z.1    Kopecký, V.2    Hofbauerová, K.3    Hovorková, P.4    Rípová, D.5
  • 78
    • 79955955895 scopus 로고    scopus 로고
    • Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime
    • P. Gamba, G. Leonarduzzi, E. Tamagno, M. Guglielmotto, G. Testa, B. Sottero, S. Gargiulo, F. Biasi, A. Mauro, J. Viña, and G. Poli Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime Aging Cell 10 2011 403 417
    • (2011) Aging Cell , vol.10 , pp. 403-417
    • Gamba, P.1    Leonarduzzi, G.2    Tamagno, E.3    Guglielmotto, M.4    Testa, G.5    Sottero, B.6    Gargiulo, S.7    Biasi, F.8    Mauro, A.9    Viña, J.10    Poli, G.11
  • 80
    • 0033528279 scopus 로고    scopus 로고
    • The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells
    • H. Kölsch, D. Lütjohann, A. Tulke, I. Björkhem, and M.L. Rao The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells Brain Res. 818 1999 171 175
    • (1999) Brain Res. , vol.818 , pp. 171-175
    • Kölsch, H.1    Lütjohann, D.2    Tulke, A.3    Björkhem, I.4    Rao, M.L.5
  • 81
    • 0034904940 scopus 로고    scopus 로고
    • Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17β.
    • H. Kölsch, M. Ludwig, D. Lütjohann, and M.L. Rao Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17β. J. Neural Transmission 108 2001 475 488
    • (2001) J. Neural Transmission , vol.108 , pp. 475-488
    • Kölsch, H.1    Ludwig, M.2    Lütjohann, D.3    Rao, M.L.4
  • 82
    • 84898825097 scopus 로고    scopus 로고
    • Diverse functions of 24(S)-hydroxycholesterol in the brain: a special issue on oxysterols
    • N. Noguchi, Y. Saito, and Y. Urano Diverse functions of 24(S)-hydroxycholesterol in the brain: a special issue on oxysterols Biochem. Biophys. Res. Commun. 446 2014 692 696
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 692-696
    • Noguchi, N.1    Saito, Y.2    Urano, Y.3
  • 83
    • 79960111702 scopus 로고    scopus 로고
    • 24(S)-Hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis
    • K. Yamanaka, Y. Saito, T. Yamamori, Y. Urano, and N. Noguchi 24(S)-Hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis J. Biol. Chem. 286 2011 24666 24673
    • (2011) J. Biol. Chem. , vol.286 , pp. 24666-24673
    • Yamanaka, K.1    Saito, Y.2    Yamamori, T.3    Urano, Y.4    Noguchi, N.5
  • 84
    • 84865246069 scopus 로고    scopus 로고
    • A novel fluorescent probe with high sensitivity and selective detection of lipid hydroperoxides in cells
    • K. Yamanaka, Y. Saito, J. Sakiyama, Y. Ohuchi, F. Oseto, and N. Noguchi A novel fluorescent probe with high sensitivity and selective detection of lipid hydroperoxides in cells RSC Adv 2 2012 7894 7900
    • (2012) RSC Adv , vol.2 , pp. 7894-7900
    • Yamanaka, K.1    Saito, Y.2    Sakiyama, J.3    Ohuchi, Y.4    Oseto, F.5    Noguchi, N.6
  • 85
    • 43749104015 scopus 로고    scopus 로고
    • Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells
    • M. Jiang, K. Zhu, J. Grenet, and J.M. Lahti Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells Biochim. Biophys. Acta 1783 2008 1055 1067
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 1055-1067
    • Jiang, M.1    Zhu, K.2    Grenet, J.3    Lahti, J.M.4
  • 86
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • L. Sun, H. Wang, Z. Wang, S. He, S. Chen, D. Liao, L. Wang, J. Yan, W. Liu, X. Lei, and X. Wang Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase Cell 148 2012 213 227
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6    Wang, L.7    Yan, J.8    Liu, W.9    Lei, X.10    Wang, X.11
  • 87
    • 84898027331 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3
    • H. Wang, L. Sun, L. Su, J. Rizo, L. Liu, L.F. Wang, F.S. Wang, and X. Wang Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3 Mol. Cell 54 2014 133 146
    • (2014) Mol. Cell , vol.54 , pp. 133-146
    • Wang, H.1    Sun, L.2    Su, L.3    Rizo, J.4    Liu, L.5    Wang, L.F.6    Wang, F.S.7    Wang, X.8
  • 89
    • 84937410053 scopus 로고    scopus 로고
    • 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8
    • D.K. Vo, Y. Urano, W. Takabe, Y. Saito, and N. Noguchi 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8 Steroids 99 2015 230 237
    • (2015) Steroids , vol.99 , pp. 230-237
    • Vo, D.K.1    Urano, Y.2    Takabe, W.3    Saito, Y.4    Noguchi, N.5
  • 90
    • 84891771031 scopus 로고    scopus 로고
    • Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1
    • K. Yamanaka, Y. Urano, W. Takabe, Y. Saito, and N. Noguchi Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1 Cell Death Dis. 5 2014 e990
    • (2014) Cell Death Dis. , vol.5 , pp. e990
    • Yamanaka, K.1    Urano, Y.2    Takabe, W.3    Saito, Y.4    Noguchi, N.5
  • 92
    • 84903182820 scopus 로고    scopus 로고
    • The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells
    • V.L. Marca, M.S. Spagnuolo, L. Cigliano, D. Marasco, and P. Abrescia The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells J. Neurochem. 130 2014 97 108
    • (2014) J. Neurochem. , vol.130 , pp. 97-108
    • Marca, V.L.1    Spagnuolo, M.S.2    Cigliano, L.3    Marasco, D.4    Abrescia, P.5
  • 93
    • 84872308031 scopus 로고    scopus 로고
    • A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes
    • M.X. He, and Y.W. He A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes Cell Death Differ. 20 2013 188 197
    • (2013) Cell Death Differ. , vol.20 , pp. 188-197
    • He, M.X.1    He, Y.W.2


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