Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated pc12 cells by suppressing mitochondrial membrane permeability change

Neurochemical Research

Volumn 34, Issue 8, 2009, Pages 1433-1442

  Kim, Doo Eung ^a   Youn, Young Chul ^b   Kim, Young Ki ^c   Hong, Ki Moo ^d   Lee, Chung Soo ^d  

^a Seoul Veterans Hospital   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

^c University of Ulsan   (South Korea)

^d Chung Ang University   (South Korea)

Author keywords

18 Glycyrrhetinic acid; 7 Ketocholesterol; Glycyrrhizin; Mitochondria mediated cell death; PC12 cells; Protection

Indexed keywords

7 OXOCHOLESTEROL; CASPASE 3; CYTOCHROME C; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; PROTEIN BAX;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL LEVEL; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; FLOW CYTOMETRY; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; KETOCHOLESTEROLS; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; PC12 CELLS; PERMEABILITY; RATS;

GLYCYRRHIZA;

EID: 67349087552     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-9930-y     Document Type: Article

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