The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells

Journal of Neurochemistry

Volumn 130, Issue 1, 2014, Pages 97-108

  La Marca, Valeria ^a   Spagnuolo, Maria Stefania ^b   Cigliano, Luisa ^a,c   Marasco, Daniela ^a,c   Abrescia, Paolo ^a,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CNR   (Italy)

^c Centro Interuniversitario di Ricerca Sui Peptidi Bioattivi   (Italy)

Author keywords

ApoA I; ApoE; cerebrosterol; haptoglobin; LCAT; neuron culture

Indexed keywords

1 PALMITOYL 2 [6 [(7 NITRO 2 1,3 BENZOXADIAZOL 4 YL)AMINO]HEXANOYL]SN GLYCERO 3 PHOSPHOCHOLINE; 24 HYDROXYCHOLESTEROL; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; CHOLESTEROL; ESTER DERIVATIVE; GLYCEROPHOSPHORYLCHOLINE DERIVATIVE; HAPTOGLOBIN; OXYSTEROL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PROTEOLIPOSOME; UNCLASSIFIED DRUG; 24-HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE;

ADULT; ARTICLE; CATALYSIS; CELL DIFFERENTIATION; CELL SURVIVAL; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; ESTERIFICATION; HUMAN; INFLAMMATION; MALE; NERVE CELL CULTURE; NEUROTOXICITY; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; MIDDLE AGED; NERVE CELL; PHYSIOLOGY; TOXICITY; TUMOR CELL LINE;

CELL LINE, TUMOR; CELLS, CULTURED; ENZYME ACTIVATION; ESTERIFICATION; HUMANS; HYDROXYCHOLESTEROLS; MALE; MIDDLE AGED; NEURONS; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE;

EID: 84903182820     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12713     Document Type: Article

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