-
1
-
-
84931576897
-
Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss
-
R.R. Ager, and et al. Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss Hippocampus 25 7 2015 813 826 10.1002/hipo.22405
-
(2015)
Hippocampus
, vol.25
, Issue.7
, pp. 813-826
-
-
Ager, R.R.1
-
2
-
-
84904544563
-
An update on drug treatment options of Alzheimer's disease
-
M. Allgaier, and C. Allgaier An update on drug treatment options of Alzheimer's disease Front. Biosci 19 2014 1345 1354
-
(2014)
Front. Biosci
, vol.19
, pp. 1345-1354
-
-
Allgaier, M.1
Allgaier, C.2
-
3
-
-
61449171881
-
Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
-
N. Amariglio, and et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient PLoS Med 6 2009 e1000029 10.1371/journal.pmed.1000029
-
(2009)
PLoS Med
, vol.6
, pp. e1000029
-
-
Amariglio, N.1
-
4
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
C. Andorfer, and et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms J. Neurochem 86 2003 582 590
-
(2003)
J. Neurochem
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
-
5
-
-
77953675879
-
Probing the biology of Alzheimer's disease in mice
-
K.H. Ashe, and K.R. Zahs Probing the biology of Alzheimer's disease in mice Neuron 66 2010 631 645 10.1016/j.neuron.2010.04.031
-
(2010)
Neuron
, vol.66
, pp. 631-645
-
-
Ashe, K.H.1
Zahs, K.R.2
-
6
-
-
79952747862
-
Alzheimer's disease
-
C. Ballard, and et al. Alzheimer's disease Lancet 377 2011 1019 1031 10.1016/S0140-6736(10)61349-9
-
(2011)
Lancet
, vol.377
, pp. 1019-1031
-
-
Ballard, C.1
-
8
-
-
0035887736
-
Selective immunolesions of cholinergic neurons in mice: Effects on neuroanatomy, neurochemistry, and behavior
-
J. Berger-Sweeney, and et al. Selective immunolesions of cholinergic neurons in mice: effects on neuroanatomy, neurochemistry, and behavior J. Neurosci 21 2001 8164 8173
-
(2001)
J. Neurosci
, vol.21
, pp. 8164-8173
-
-
Berger-Sweeney, J.1
-
9
-
-
77955908261
-
Generation of microglial cells from mouse embryonic stem cells
-
C. Beutner, K. Roy, B. Linnartz, I. Napoli, and H. Neumann Generation of microglial cells from mouse embryonic stem cells Nat. Protoc 5 2010 1481 1494 10.1038/nprot.2010.90
-
(2010)
Nat. Protoc
, vol.5
, pp. 1481-1494
-
-
Beutner, C.1
Roy, K.2
Linnartz, B.3
Napoli, I.4
Neumann, H.5
-
10
-
-
79955411486
-
The controlled generation of functional basal forebrain cholinergic neurons from human embryonic stem cells
-
C.J. Bissonnette, and et al. The controlled generation of functional basal forebrain cholinergic neurons from human embryonic stem cells Stem Cells 29 2011 802 811 10.1002/stem.626
-
(2011)
Stem Cells
, vol.29
, pp. 802-811
-
-
Bissonnette, C.J.1
-
11
-
-
69449091994
-
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
-
M. Blurton-Jones, and et al. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease Proc. Natl. Acad. Sci. U.S.A. 106 2009 13594 13599 10.1073/pnas.0901402106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 13594-13599
-
-
Blurton-Jones, M.1
-
12
-
-
0029967424
-
Sheep cloned by nuclear transfer from a cultured cell line
-
K.H. Campbell, J. McWhir, W.A. Ritchie, and I. Wilmut Sheep cloned by nuclear transfer from a cultured cell line Nature 380 1996 64 66 10.1038/380064a0
-
(1996)
Nature
, vol.380
, pp. 64-66
-
-
Campbell, K.H.1
McWhir, J.2
Ritchie, W.A.3
Wilmut, I.4
-
13
-
-
0033869715
-
Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: Differential effects of APOE genotype and presenilin mutations
-
A.M. Cataldo, and et al. Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations Am. J. Pathol 157 2000 277 286
-
(2000)
Am. J. Pathol
, vol.157
, pp. 277-286
-
-
Cataldo, A.M.1
-
14
-
-
84901661940
-
Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?
-
J. Cedernaes, H.B. Schioth, and C. Benedict Efficacy of antibody-based therapies to treat Alzheimer's disease: just a matter of timing? Exp. Gerontol 57 2014 104 106 10.1016/j.exger.2014.05.002
-
(2014)
Exp. Gerontol
, vol.57
, pp. 104-106
-
-
Cedernaes, J.1
Schioth, H.B.2
Benedict, C.3
-
15
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
S.M. Chambers, and et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling Nat. Biotechnol 27 2009 275 280 10.1038/nbt.1529
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
-
16
-
-
84924219718
-
Generation of induced neuronal cells by the single reprogramming factor ASCL1
-
S. Chanda, and et al. Generation of induced neuronal cells by the single reprogramming factor ASCL1 Stem Cell Rep 3 2014 282 296 10.1016/j.stemcr.2014.05.020
-
(2014)
Stem Cell Rep
, vol.3
, pp. 282-296
-
-
Chanda, S.1
-
17
-
-
84896836202
-
Human pluripotent stem cell culture: Considerations for maintenance, expansion, and therapeutics
-
Chen K.G., B.S. Mallon, R.D. McKay, and P.G. Robey Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics Cell Stem Cell 14 2014 13 26 10.1016/j.stem.2013.12.005
-
(2014)
Cell Stem Cell
, vol.14
, pp. 13-26
-
-
Chen, K.G.1
Mallon, B.S.2
McKay, R.D.3
Robey, P.G.4
-
18
-
-
84912064761
-
A three-dimensional human neural cell culture model of Alzheimer's disease
-
S.H. Choi, and et al. A three-dimensional human neural cell culture model of Alzheimer's disease Nature 515 2014 274 278 10.1038/nature13800
-
(2014)
Nature
, vol.515
, pp. 274-278
-
-
Choi, S.H.1
-
19
-
-
84872185150
-
Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain
-
K.J. Christie, and A.M. Turnley Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain Front. Cell. Neurosci 6 2012 70 10.3389/fncel.2012.00070
-
(2012)
Front. Cell. Neurosci
, vol.6
, pp. 70
-
-
Christie, K.J.1
Turnley, A.M.2
-
21
-
-
33646119401
-
Hematopoietic stem-cell transplantation
-
E.A. Copelan Hematopoietic stem-cell transplantation N. Engl. J. Med 354 2006 1813 1826 10.1056/NEJMra052638
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1813-1826
-
-
Copelan, E.A.1
-
22
-
-
84883761513
-
Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling
-
L.A. Crompton, and et al. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling Stem Cell Res 11 2013 1206 1221 10.1016/j.scr.2013.08.002
-
(2013)
Stem Cell Res
, vol.11
, pp. 1206-1221
-
-
Crompton, L.A.1
-
23
-
-
0023663888
-
Expression of a single transfected cDNA converts fibroblasts to myoblasts
-
R.L. Davis, H. Weintraub, and A.B. Lassar Expression of a single transfected cDNA converts fibroblasts to myoblasts Cell 51 1987 987 1000
-
(1987)
Cell
, vol.51
, pp. 987-1000
-
-
Davis, R.L.1
Weintraub, H.2
Lassar, A.B.3
-
24
-
-
34247473080
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
-
F.P. Di Giorgio, M.A. Carrasco, M.C. Siao, T. Maniatis, and K. Eggan Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model Nat. Neurosci 10 2007 608 614 10.1038/nn1885
-
(2007)
Nat. Neurosci
, vol.10
, pp. 608-614
-
-
Di Giorgio, F.P.1
Carrasco, M.A.2
Siao, M.C.3
Maniatis, T.4
Eggan, K.5
-
25
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
J.T. Dimos, and et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons Science 321 2008 1218 1221 10.1126/science.1158799
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
-
26
-
-
84913594397
-
Genome editing. The new frontier of genome engineering with CRISPR-Cas9
-
J.A. Doudna, and E. Charpentier Genome editing. The new frontier of genome engineering with CRISPR-Cas9 Science 346 2014 1258096 10.1126/science.1258096
-
(2014)
Science
, vol.346
, pp. 1258096
-
-
Doudna, J.A.1
Charpentier, E.2
-
27
-
-
84892188499
-
Stem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death
-
Duan L., and et al. Stem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death Mol. Neurodegener 9 2014 3 10.1186/1750-1326-9-3
-
(2014)
Mol. Neurodegener
, vol.9
, pp. 3
-
-
Duan, L.1
-
28
-
-
54949102049
-
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals
-
M. Eiraku, and et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals Cell Stem Cell 3 2008 519 532 10.1016/j.stem.2008.09.002
-
(2008)
Cell Stem Cell
, vol.3
, pp. 519-532
-
-
Eiraku, M.1
-
30
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
M.J. Evans, and M.H. Kaufman Establishment in culture of pluripotential cells from mouse embryos Nature 292 1981 154 156
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
31
-
-
84901272462
-
Clinical applications of mesenchymal stem cells in chronic diseases
-
A. Farini, C. Sitzia, S. Erratico, M. Meregalli, and Y. Torrente Clinical applications of mesenchymal stem cells in chronic diseases Stem Cells Int 2014 2014 306573 10.1155/2014/306573
-
(2014)
Stem Cells Int
, vol.2014
, pp. 306573
-
-
Farini, A.1
Sitzia, C.2
Erratico, S.3
Meregalli, M.4
Torrente, Y.5
-
32
-
-
70450195439
-
LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons
-
A. Fragkouli, N.V. van Wijk, R. Lopes, N. Kessaris, and V. Pachnis LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons Development 136 2009 3841 3851 10.1242/dev.038083
-
(2009)
Development
, vol.136
, pp. 3841-3851
-
-
Fragkouli, A.1
Van Wijk, N.V.2
Lopes, R.3
Kessaris, N.4
Pachnis, V.5
-
33
-
-
84857644799
-
Embryonic stem cell pioneer Geron exits field, cuts losses
-
S. Frantz Embryonic stem cell pioneer Geron exits field, cuts losses Nat. Biotechnol 30 2012 12 13 10.1038/nbt0112-12
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 12-13
-
-
Frantz, S.1
-
34
-
-
39749095115
-
Omega-3 supplementation in mild to moderate Alzheimer's disease: Effects on neuropsychiatric symptoms
-
Y. Freund-Levi, and et al. Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms Int. J. Geriatr. Psychiatry 23 2008 161 169 10.1002/gps.1857
-
(2008)
Int. J. Geriatr. Psychiatry
, vol.23
, pp. 161-169
-
-
Freund-Levi, Y.1
-
35
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo Q., and et al. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice Nat. Med 5 1999 101 106 10.1038/4789
-
(1999)
Nat. Med
, vol.5
, pp. 101-106
-
-
Guo, Q.1
-
36
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
J. Hanna, and et al. Direct cell reprogramming is a stochastic process amenable to acceleration Nature 462 2009 595 601 10.1038/nature08592
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
-
37
-
-
84897954222
-
TREM2 and the neuroimmunology of Alzheimer's disease
-
S.E. Hickman, and J. El Khoury TREM2 and the neuroimmunology of Alzheimer's disease Biochem. Pharmacol 88 2014 495 498 10.1016/j.bcp.2013.11.021
-
(2014)
Biochem. Pharmacol
, vol.88
, pp. 495-498
-
-
Hickman, S.E.1
El Khoury, J.2
-
38
-
-
84902214868
-
Vectorology and factor delivery in induced pluripotent stem cell reprogramming
-
Hu K. Vectorology and factor delivery in induced pluripotent stem cell reprogramming Stem Cells Dev 23 2014 1301 1315 10.1089/scd.2013.0621
-
(2014)
Stem Cells Dev
, vol.23
, pp. 1301-1315
-
-
Hu, K.1
-
39
-
-
84863337843
-
Alzheimer mechanisms and therapeutic strategies
-
Huang Y., and L. Mucke Alzheimer mechanisms and therapeutic strategies Cell 148 2012 1204 1222 10.1016/j.cell.2012.02.040
-
(2012)
Cell
, vol.148
, pp. 1204-1222
-
-
Huang, Y.1
Mucke, L.2
-
40
-
-
84898608302
-
IPS cells: A game changer for future medicine
-
H. Inoue, N. Nagata, H. Kurokawa, and S. Yamanaka iPS cells: a game changer for future medicine EMBO J. 33 2014 409 417 10.1002/embj.201387098
-
(2014)
EMBO J.
, vol.33
, pp. 409-417
-
-
Inoue, H.1
Nagata, N.2
Kurokawa, H.3
Yamanaka, S.4
-
41
-
-
84856956771
-
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
-
M.A. Israel, and et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells Nature 482 2012 216 220 10.1038/nature10821
-
(2012)
Nature
, vol.482
, pp. 216-220
-
-
Israel, M.A.1
-
42
-
-
84926246629
-
Toward beta cell replacement for diabetes
-
B. Johannesson, L. Sui, D.O. Freytes, R.J. Creusot, and D. Egli Toward beta cell replacement for diabetes EMBO J. 34 7 2015 841 855 10.15252/embj.201490685
-
(2015)
EMBO J.
, vol.34
, Issue.7
, pp. 841-855
-
-
Johannesson, B.1
Sui, L.2
Freytes, D.O.3
Creusot, R.J.4
Egli, D.5
-
43
-
-
84875916922
-
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness
-
T. Kondo, and et al. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness Cell Stem Cell 12 2013 487 496 10.1016/j.stem.2013.01.009
-
(2013)
Cell Stem Cell
, vol.12
, pp. 487-496
-
-
Kondo, T.1
-
44
-
-
84884414984
-
Cerebral organoids model human brain development and microcephaly
-
M.A. Lancaster, and et al. Cerebral organoids model human brain development and microcephaly Nature 501 2013 373 379 10.1038/nature12517
-
(2013)
Nature
, vol.501
, pp. 373-379
-
-
Lancaster, M.A.1
-
45
-
-
84906318882
-
Considering a new paradigm for Alzheimer's disease research
-
G.R. Langley Considering a new paradigm for Alzheimer's disease research Drug Discov. Today 19 2014 1114 1124 10.1016/j.drudis.2014.03.013
-
(2014)
Drug Discov. Today
, vol.19
, pp. 1114-1124
-
-
Langley, G.R.1
-
46
-
-
84882239370
-
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
-
A.S. Lee, Tang C., Rao M.S., I.L. Weissman, and Wu J.C. Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies Nat. Med 19 2013 998 1004 10.1038/nm.3267
-
(2013)
Nat. Med
, vol.19
, pp. 998-1004
-
-
Lee, A.S.1
Tang, C.2
Rao, M.S.3
Weissman, I.L.4
Wu, J.C.5
-
47
-
-
84894460947
-
A cut above the rest: Targeted genome editing technologies in human pluripotent stem cells
-
Li M., K. Suzuki, N.Y. Kim, Liu G.H., and J.C. Izpisua Belmonte A cut above the rest: targeted genome editing technologies in human pluripotent stem cells J. Biol. Chem 289 2014 4594 4599 10.1074/jbc.R113.488247
-
(2014)
J. Biol. Chem
, vol.289
, pp. 4594-4599
-
-
Li, M.1
Suzuki, K.2
Kim, N.Y.3
Liu, G.H.4
Izpisua Belmonte, J.C.5
-
48
-
-
77049107114
-
Neuronal gene expression in non-demented individuals with intermediate Alzheimer's disease neuropathology
-
Liang W.S., and et al. Neuronal gene expression in non-demented individuals with intermediate Alzheimer's disease neuropathology Neurobiol. Aging 31 2010 549 566 10.1016/j.neurobiolaging.2008.05.013
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 549-566
-
-
Liang, W.S.1
-
49
-
-
84877342649
-
Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
-
Liu Y., and et al. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits Nat. Biotechnol 31 2013 440 447 10.1038/nbt.2565
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 440-447
-
-
Liu, Y.1
-
50
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
G.R. Martin Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proc. Natl. Acad. Sci. U.S.A. 78 1981 7634 7638
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
51
-
-
84890109489
-
Human iPSC-based modeling of late-onset disease via progerin-induced aging
-
J.D. Miller, and et al. Human iPSC-based modeling of late-onset disease via progerin-induced aging Cell Stem Cell 13 2013 691 705 10.1016/j.stem.2013.11.006
-
(2013)
Cell Stem Cell
, vol.13
, pp. 691-705
-
-
Miller, J.D.1
-
52
-
-
84933677790
-
APP metabolism regulates Tau proteostasis in human cerebral cortex neurons
-
S. Moore, and et al. APP metabolism regulates Tau proteostasis in human cerebral cortex neurons Cell Rep 11 2015 689 696 10.1016/j.celrep.2015.03.068
-
(2015)
Cell Rep
, vol.11
, pp. 689-696
-
-
Moore, S.1
-
53
-
-
84055213663
-
Adult hippocampal neurogenesis and its role in Alzheimer's disease
-
Mu Y., and F.H. Gage Adult hippocampal neurogenesis and its role in Alzheimer's disease Mol. Neurodegener 6 2011 85 10.1186/1750-1326-6-85
-
(2011)
Mol. Neurodegener
, vol.6
, pp. 85
-
-
Mu, Y.1
Gage, F.H.2
-
54
-
-
84902303124
-
The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
-
C.R. Muratore, and et al. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons Hum. Mol. Genet 23 2014 3523 3536 10.1093/hmg/ddu064
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. 3523-3536
-
-
Muratore, C.R.1
-
55
-
-
84877337520
-
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells
-
F.J. Najm, and et al. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells Nat. Biotechnol 31 2013 426 433 10.1038/nbt.2561
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 426-433
-
-
Najm, F.J.1
-
56
-
-
80053916211
-
Human oocytes reprogram somatic cells to a pluripotent state
-
S. Noggle, and et al. Human oocytes reprogram somatic cells to a pluripotent state Nature 478 2011 70 75 10.1038/nature10397
-
(2011)
Nature
, vol.478
, pp. 70-75
-
-
Noggle, S.1
-
57
-
-
0029554875
-
A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene
-
J. Perez-Tur, and et al. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene Neuroreport 7 1995 297 301
-
(1995)
Neuroreport
, vol.7
, pp. 297-301
-
-
Perez-Tur, J.1
-
58
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
U. Pfisterer, and et al. Direct conversion of human fibroblasts to dopaminergic neurons Proc. Natl. Acad. Sci. U.S.A. 108 2011 10343 10348 10.1073/pnas.1105135108
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 10343-10348
-
-
Pfisterer, U.1
-
59
-
-
0023080585
-
Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
-
R.E. Pitas, J.K. Boyles, S.H. Lee, D. Foss, and R.W. Mahley Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins Biochim. Biophys. Acta 917 1987 148 161
-
(1987)
Biochim. Biophys. Acta
, vol.917
, pp. 148-161
-
-
Pitas, R.E.1
Boyles, J.K.2
Lee, S.H.3
Foss, D.4
Mahley, R.W.5
-
60
-
-
84905706814
-
Knock-in of human BACE1 cleaves murine APP and reiterates Alzheimer-like phenotypes
-
K. Plucinska, and et al. Knock-in of human BACE1 cleaves murine APP and reiterates Alzheimer-like phenotypes J. Neurosci 34 2014 10710 10728 10.1523/JNEUROSCI.0433-14.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 10710-10728
-
-
Plucinska, K.1
-
61
-
-
84904976176
-
A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs)
-
D. Pre, and et al. A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs) PLoS ONE 9 2014 e103418 10.1371/journal.pone.0103418
-
(2014)
PLoS ONE
, vol.9
, pp. e103418
-
-
Pre, D.1
-
62
-
-
41149140767
-
The value of incomplete mouse models of Alzheimer's disease
-
R. Radde, C. Duma, M. Goedert, and M. Jucker The value of incomplete mouse models of Alzheimer's disease Eur. J. Nucl. Med. Mol. Imaging 35 Suppl. 1 2008 S70 S74 10.1007/s00259-007-0704-y
-
(2008)
Eur. J. Nucl. Med. Mol. Imaging
, vol.35
, pp. S70-S74
-
-
Radde, R.1
Duma, C.2
Goedert, M.3
Jucker, M.4
-
63
-
-
84907752479
-
Japan stem-cell trial stirs envy
-
S. Reardon, and D. Cyranoski Japan stem-cell trial stirs envy Nature 513 2014 287 288 10.1038/513287a
-
(2014)
Nature
, vol.513
, pp. 287-288
-
-
Reardon, S.1
Cyranoski, D.2
-
64
-
-
84863625049
-
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor
-
K.L. Ring, and et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor Cell Stem Cell 11 2012 100 109 10.1016/j.stem.2012.05.018
-
(2012)
Cell Stem Cell
, vol.11
, pp. 100-109
-
-
Ring, K.L.1
-
65
-
-
84906829737
-
Human-induced pluripotent stem cells: Potential for neurodegenerative diseases
-
C.A. Ross, and S.S. Akimov Human-induced pluripotent stem cells: potential for neurodegenerative diseases Hum. Mol. Genet 23 2014 R17 R26 10.1093/hmg/ddu204
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. R17-R26
-
-
Ross, C.A.1
Akimov, S.S.2
-
66
-
-
33646050649
-
Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation
-
A.D. Roth, G. Ramirez, R. Alarcon, and R. Von Bernhardi Oligodendrocytes damage in Alzheimer's disease: beta amyloid toxicity and inflammation Biol. Res 38 2005 381 387
-
(2005)
Biol. Res
, vol.38
, pp. 381-387
-
-
Roth, A.D.1
Ramirez, G.2
Alarcon, R.3
Von Bernhardi, R.4
-
67
-
-
0024342769
-
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease
-
B. Rumble, and et al. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease N. Engl. J. Med 320 1989 1446 1452 10.1056/NEJM198906013202203
-
(1989)
N. Engl. J. Med
, vol.320
, pp. 1446-1452
-
-
Rumble, B.1
-
68
-
-
2942611429
-
Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease
-
C. Schwab, M. Hosokawa, and P.L. McGeer Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease Exp. Neurol 188 2004 52 64 10.1016/j.expneurol.2004.03.016
-
(2004)
Exp. Neurol
, vol.188
, pp. 52-64
-
-
Schwab, C.1
Hosokawa, M.2
McGeer, P.L.3
-
69
-
-
84857643783
-
Embryonic stem cell trials for macular degeneration: A preliminary report
-
S.D. Schwartz, and et al. Embryonic stem cell trials for macular degeneration: a preliminary report Lancet 379 2012 713 720 10.1016/S0140-6736(12)60028-2
-
(2012)
Lancet
, vol.379
, pp. 713-720
-
-
Schwartz, S.D.1
-
70
-
-
84913587253
-
Wrongful termination: Lessons from the geron clinical trial
-
C.T. Scott, and D. Magnus Wrongful termination: lessons from the geron clinical trial Stem Cells Transl. Med 3 2014 1398 1401 10.5966/sctm.2014-0147
-
(2014)
Stem Cells Transl. Med
, vol.3
, pp. 1398-1401
-
-
Scott, C.T.1
Magnus, D.2
-
71
-
-
84937516777
-
Neurogenesis in the normal ageing hippocampus: A mini-review
-
D.R. Seib, and A. Martin-Villalba Neurogenesis in the normal ageing hippocampus: a mini-review Gerontology 2014 10.1159/000368575
-
(2014)
Gerontology
-
-
Seib, D.R.1
Martin-Villalba, A.2
-
72
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
D.J. Selkoe Alzheimer's disease is a synaptic failure Science 298 2002 789 791 10.1126/science.1074069
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
73
-
-
84863229339
-
A human stem cell model of early Alzheimer's disease pathology in Down syndrome
-
Shi Y., and et al. A human stem cell model of early Alzheimer's disease pathology in Down syndrome Sci. Transl. Med 4 2012 124ra129 10.1126/scitranslmed.3003771
-
(2012)
Sci. Transl. Med
, vol.4
, pp. 124ra129
-
-
Shi, Y.1
-
74
-
-
84870030633
-
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
-
Shi Y., P. Kirwan, and F.J. Livesey Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks Nat. Protoc 7 2012 1836 1846 10.1038/nprot.2012.116
-
(2012)
Nat. Protoc
, vol.7
, pp. 1836-1846
-
-
Shi, Y.1
Kirwan, P.2
Livesey, F.J.3
-
75
-
-
80052295767
-
Conversion of mouse and human fibroblasts into functional spinal motor neurons
-
E.Y. Son, and et al. Conversion of mouse and human fibroblasts into functional spinal motor neurons Cell Stem Cell 9 2011 205 218 10.1016/j.stem.2011.07.014
-
(2011)
Cell Stem Cell
, vol.9
, pp. 205-218
-
-
Son, E.Y.1
-
76
-
-
84897136184
-
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors
-
A.A. Sproul, and et al. Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors PLoS ONE 9 2014 e84547 10.1371/journal.pone.0084547
-
(2014)
PLoS ONE
, vol.9
, pp. e84547
-
-
Sproul, A.A.1
-
77
-
-
84897954126
-
Generation of iPSC lines from archived non-cryoprotected biobanked dura mater
-
A.A. Sproul, and et al. Generation of iPSC lines from archived non-cryoprotected biobanked dura mater Acta Neuropathol. Commun 2 2014 4 10.1186/2051-5960-2-4
-
(2014)
Acta Neuropathol. Commun
, vol.2
, pp. 4
-
-
Sproul, A.A.1
-
78
-
-
84878838747
-
Human embryonic stem cells derived by somatic cell nuclear transfer
-
M. Tachibana, and et al. Human embryonic stem cells derived by somatic cell nuclear transfer Cell 153 2013 1228 1238 10.1016/j.cell.2013.05.006
-
(2013)
Cell
, vol.153
, pp. 1228-1238
-
-
Tachibana, M.1
-
79
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676 10.1016/j.cell.2006.07.024
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
80
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
J.A. Thomson, and et al. Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
-
81
-
-
41749096713
-
A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia
-
T. Tomiyama, and et al. A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia Ann. Neurol 63 2008 377 387 10.1002/ana.21321
-
(2008)
Ann. Neurol
, vol.63
, pp. 377-387
-
-
Tomiyama, T.1
-
82
-
-
84904344899
-
Inhibitory interneuron progenitor transplantation restores normal learning and memory in ApoE4 knock-in mice without or with Abeta accumulation
-
Tong L.M., and et al. Inhibitory interneuron progenitor transplantation restores normal learning and memory in ApoE4 knock-in mice without or with Abeta accumulation J. Neurosci 34 2014 9506 9515 10.1523/JNEUROSCI.0693-14.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 9506-9515
-
-
Tong, L.M.1
-
83
-
-
77955483685
-
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects
-
J.Q. Trojanowski, and et al. Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects Alzheimers Dement 6 2010 230 238 10.1016/j.jalz.2010.03.008
-
(2010)
Alzheimers Dement
, vol.6
, pp. 230-238
-
-
Trojanowski, J.Q.1
-
84
-
-
13844292402
-
Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma
-
T. Tsuchiya, and et al. Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma J. Neuroimmunol 160 2005 210 218 10.1016/j.jneuroim.2004.10.025
-
(2005)
J. Neuroimmunol
, vol.160
, pp. 210-218
-
-
Tsuchiya, T.1
-
85
-
-
84885101524
-
Toward the development of a global induced pluripotent stem cell library
-
M. Turner, and et al. Toward the development of a global induced pluripotent stem cell library Cell Stem Cell 13 2013 382 384 10.1016/j.stem.2013.08.003
-
(2013)
Cell Stem Cell
, vol.13
, pp. 382-384
-
-
Turner, M.1
-
86
-
-
70350455062
-
The beta-secretase enzyme BACE in health and Alzheimer's disease: Regulation, cell biology, function, and therapeutic potential
-
R. Vassar, D.M. Kovacs, Yan R., and P.C. Wong The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential J. Neurosci 29 2009 12787 12794 10.1523/JNEUROSCI.3657-09.2009
-
(2009)
J. Neurosci
, vol.29
, pp. 12787-12794
-
-
Vassar, R.1
Kovacs, D.M.2
Yan, R.3
Wong, P.C.4
-
87
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
T. Vierbuchen, and et al. Direct conversion of fibroblasts to functional neurons by defined factors Nature 463 2010 1035 1041 10.1038/nature08797
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
-
88
-
-
84887534693
-
Toward pluripotency by reprogramming: Mechanisms and application
-
Wang T., S.T. Warren, and Jin P. Toward pluripotency by reprogramming: mechanisms and application Protein Cell 4 2013 820 832 10.1007/s13238-013-3074-1
-
(2013)
Protein Cell
, vol.4
, pp. 820-832
-
-
Wang, T.1
Warren, S.T.2
Jin, P.3
-
89
-
-
0033366335
-
Young neurons from medial ganglionic eminence disperse in adult and embryonic brain
-
H. Wichterle, J.M. Garcia-Verdugo, D.G. Herrera, and A. Alvarez-Buylla Young neurons from medial ganglionic eminence disperse in adult and embryonic brain Nat. Neurosci 2 1999 461 466 10.1038/8131
-
(1999)
Nat. Neurosci
, vol.2
, pp. 461-466
-
-
Wichterle, H.1
Garcia-Verdugo, J.M.2
Herrera, D.G.3
Alvarez-Buylla, A.4
-
90
-
-
84888433312
-
The presenilin-1 DeltaE9 mutation results in reduced gamma-secretase activity, but not total loss of PS1 function, in isogenic human stem cells
-
G. Woodruff, and et al. The presenilin-1 DeltaE9 mutation results in reduced gamma-secretase activity, but not total loss of PS1 function, in isogenic human stem cells Cell Rep 5 2013 974 985 10.1016/j.celrep.2013.10.018
-
(2013)
Cell Rep
, vol.5
, pp. 974-985
-
-
Woodruff, G.1
-
91
-
-
81255169342
-
Modeling familial Alzheimer's disease with induced pluripotent stem cells
-
T. Yagi, and et al. Modeling familial Alzheimer's disease with induced pluripotent stem cells Hum. Mol. Genet 20 2011 4530 4539 10.1093/hmg/ddr394
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 4530-4539
-
-
Yagi, T.1
-
92
-
-
84903535623
-
Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells
-
M. Yamada, and et al. Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells Nature 510 2014 533 536 10.1038/nature13287
-
(2014)
Nature
, vol.510
, pp. 533-536
-
-
Yamada, M.1
-
93
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
A.S. Yoo, and et al. MicroRNA-mediated conversion of human fibroblasts to neurons Nature 476 2011 228 231 10.1038/nature10323
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
-
94
-
-
84896083027
-
Modeling hippocampal neurogenesis using human pluripotent stem cells
-
Yu D.X., and et al. Modeling hippocampal neurogenesis using human pluripotent stem cells Stem Cell Rep 2 2014 295 310 10.1016/j.stemcr.2014.01.009
-
(2014)
Stem Cell Rep
, vol.2
, pp. 295-310
-
-
Yu, D.X.1
-
95
-
-
77955641542
-
Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells
-
Zeng H., and et al. Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells PLoS ONE 5 2010 e11853 10.1371/journal.pone.0011853
-
(2010)
PLoS ONE
, vol.5
, pp. e11853
-
-
Zeng, H.1
-
96
-
-
84876907931
-
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease
-
Zhang B., and et al. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease Cell 153 2013 707 720 10.1016/j.cell.2013.03.030
-
(2013)
Cell
, vol.153
, pp. 707-720
-
-
Zhang, B.1
-
97
-
-
84878849645
-
Rapid single-step induction of functional neurons from human pluripotent stem cells
-
Zhang Y., and et al. Rapid single-step induction of functional neurons from human pluripotent stem cells Neuron 78 2013 785 798 10.1016/j.neuron.2013.05.029
-
(2013)
Neuron
, vol.78
, pp. 785-798
-
-
Zhang, Y.1
-
98
-
-
33846423521
-
Oligodendrocyte progenitor cells derived from human embryonic stem cells express neurotrophic factors
-
Zhang Y.W., J. Denham, and R.S. Thies Oligodendrocyte progenitor cells derived from human embryonic stem cells express neurotrophic factors Stem Cells Dev 15 2006 943 952 10.1089/scd.2006.15.943
-
(2006)
Stem Cells Dev
, vol.15
, pp. 943-952
-
-
Zhang, Y.W.1
Denham, J.2
Thies, R.S.3
-
100
-
-
84894413040
-
Direct conversion of human fibroblasts into neuronal restricted progenitors
-
Zou Q., and et al. Direct conversion of human fibroblasts into neuronal restricted progenitors J. Biol. Chem 289 2014 5250 5260 10.1074/jbc.M113.516112
-
(2014)
J. Biol. Chem
, vol.289
, pp. 5250-5260
-
-
Zou, Q.1
|