-
1
-
-
78049353258
-
Alcohol impairs interferon signaling and enhances full cycle hepatitis C virus JFH-1 infection of human hepatocytes
-
Ye, L.; Wang, S.; Wang, X.; Zhou, Y.; Li, J.; Persidsky, Y.; Ho, W. Alcohol impairs interferon signaling and enhances full cycle hepatitis C virus JFH-1 infection of human hepatocytes. Drug Alcohol Depend. 2010, 112, 107-116.
-
(2010)
Drug Alcohol Depend
, vol.112
, pp. 107-116
-
-
Ye, L.1
Wang, S.2
Wang, X.3
Zhou, Y.4
Li, J.5
Persidsky, Y.6
Ho, W.7
-
3
-
-
33645359715
-
Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity
-
Szabo, G.; Aloman, C.; Polyak, S. J.; Weinman, S. A.; Wands, J.; Zakhari, S. Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity. Alcohol. Clin. Exp. Res. 2006, 30, 709-719.
-
(2006)
Alcohol. Clin. Exp. Res
, vol.30
, pp. 709-719
-
-
Szabo, G.1
Aloman, C.2
Polyak, S.J.3
Weinman, S.A.4
Wands, J.5
Zakhari, S.6
-
4
-
-
0033932394
-
Effect of alcohol consumption on the progression of hepatitis C virus infection and risk of hepatocellular carcinoma in Japanese patients
-
Khan, K. N.; Yatsuhashi, H. Effect of alcohol consumption on the progression of hepatitis C virus infection and risk of hepatocellular carcinoma in Japanese patients. Alcohol Alcohol. 2000, 35, 286-295.
-
(2000)
Alcohol Alcohol
, vol.35
, pp. 286-295
-
-
Khan, K.N.1
Yatsuhashi, H.2
-
5
-
-
0030933395
-
Natural history of liver fibrosis progression in patients with chronic hepatitis C
-
Poynard, T.; Bedossa, P.; Opolon, P.; The Obsvirc, Metavir, Clinivir, and Dosvirc Groups. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997, 349, 825-832.
-
(1997)
Lancet
, vol.349
, pp. 825-832
-
-
Poynard, T.1
Bedossa, P.2
Opolon, P.3
-
6
-
-
0027970413
-
Efficacy of interferon therapy in patients with chronic hepatitis C: Comparison between non-drinkers and drinkers
-
Okazaki, T.; Yoshihara, H.; Suzuki, K.; Yamada, Y.; Tsujimura, T.; Kawano, K.; Abe, H. Efficacy of interferon therapy in patients with chronic hepatitis C: Comparison between non-drinkers and drinkers. Scand. J. Gastroenterol. 1994, 29, 1039-1043.
-
(1994)
Scand. J. Gastroenterol
, vol.29
, pp. 1039-1043
-
-
Okazaki, T.1
Yoshihara, H.2
Suzuki, K.3
Yamada, Y.4
Tsujimura, T.5
Kawano, K.6
Abe, H.7
-
7
-
-
0037310610
-
Hepatitis C and alcohol
-
Lieber, C. S. Hepatitis C and alcohol. J. Clin. Gastroenterol. 2003, 36, 100-102.
-
(2003)
J. Clin. Gastroenterol
, vol.36
, pp. 100-102
-
-
Lieber, C.S.1
-
8
-
-
11144342818
-
Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells
-
Otani, K.; Korenaga, M.; Beard, M. R.; Li, K.; Qian, T.; Showalter, L. A.; Singh, A. K.; Wang, T.; Weinman, S. A. Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology 2005, 128, 96-107.
-
(2005)
Gastroenterology
, vol.128
, pp. 96-107
-
-
Otani, K.1
Korenaga, M.2
Beard, M.R.3
Li, K.4
Qian, T.5
Showalter, L.A.6
Singh, A.K.7
Wang, T.8
Weinman, S.A.9
-
9
-
-
80052290588
-
Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway
-
Deng, L.; Shoji, I.; Ogawa, W.; Kaneda, S.; Soga, T.; Jiang, D. P.; Ide, Y. H.; Hotta, H. Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway. J. Virol. 2011, 85, 8556-8568.
-
(2011)
J. Virol
, vol.85
, pp. 8556-8568
-
-
Deng, L.1
Shoji, I.2
Ogawa, W.3
Kaneda, S.4
Soga, T.5
Jiang, D.P.6
Ide, Y.H.7
Hotta, H.8
-
10
-
-
33745797050
-
Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation
-
Machida, K.; Cheng, K. T.; Lai, C. K.; Jeng, K. S.; Sung, V. M.; Lai, M. M. Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation. J. Virol. 2006, 80, 7199-7207.
-
(2006)
J. Virol
, vol.80
, pp. 7199-7207
-
-
Machida, K.1
Cheng, K.T.2
Lai, C.K.3
Jeng, K.S.4
Sung, V.M.5
Lai, M.M.6
-
11
-
-
44649095826
-
Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress
-
Osna, N. A.; White, R. L.; Krutik, V. M.; Wang, T.; Weinman, S. A.; Donohue, T. M., Jr. Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress. Gastroenterology 2008, 134, 2144-2152.
-
(2008)
Gastroenterology
, vol.134
, pp. 2144-2152
-
-
Osna, N.A.1
White, R.L.2
Krutik, V.M.3
Wang, T.4
Weinman, S.A.5
Donohue, T.M.6
-
12
-
-
67649946750
-
Hepatitis C virus and alcohol
-
Siu, L.; Foont, J.; Wands, J. R. Hepatitis C virus and alcohol. Semin. Liver Dis. 2009, 29, 188-199.
-
(2009)
Semin. Liver Dis
, vol.29
, pp. 188-199
-
-
Siu, L.1
Foont, J.2
Wands, J.R.3
-
13
-
-
34547932626
-
Mechanisms of synergy between alcohol and hepatitis C virus
-
Singal, A. K.; Anand, B. S. Mechanisms of synergy between alcohol and hepatitis C virus. J. Clin. Gastroenterol. 2007, 41, 761-772.
-
(2007)
J. Clin. Gastroenterol
, vol.41
, pp. 761-772
-
-
Singal, A.K.1
Anand, B.S.2
-
14
-
-
0033063223
-
Hepatitis crna quasispecies complexity in patients with alcoholic liver disease
-
Sherman, K. E.; Rouster, S. D.; Mendenhall, C.; Thee, D. Hepatitis crna quasispecies complexity in patients with alcoholic liver disease. Hepatology 1999, 30, 265-270.
-
(1999)
Hepatology
, vol.30
, pp. 265-270
-
-
Sherman, K.E.1
Rouster, S.D.2
Mendenhall, C.3
Thee, D.4
-
15
-
-
0035030608
-
Difference in quasispecies of the hypervariable region 1 of hepatitis C virus between alcoholic and non-alcoholic patients
-
Takahashi, K.; Takahashi, T.; Takahashi, S.; Watanabe, K.; Boku, S.; Matsui, S.; Arai, F.; Asakura, H. Difference in quasispecies of the hypervariable region 1 of hepatitis C virus between alcoholic and non-alcoholic patients. J. Gastroenterol. Hepatol. 2001, 16, 416-423.
-
(2001)
J. Gastroenterol. Hepatol
, vol.16
, pp. 416-423
-
-
Takahashi, K.1
Takahashi, T.2
Takahashi, S.3
Watanabe, K.4
Boku, S.5
Matsui, S.6
Arai, F.7
Asakura, H.8
-
16
-
-
80555129637
-
Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals
-
Seronello, S.; Montanez, J.; Presleigh, K.; Barlow, M.; Park, S. B.; Choi, J. Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals. PLOS ONE 2011, 6, e27436.
-
(2011)
PLOS ONE
, vol.6
-
-
Seronello, S.1
Montanez, J.2
Presleigh, K.3
Barlow, M.4
Park, S.B.5
Choi, J.6
-
17
-
-
56749131192
-
Alcohol metabolism increases the replication of hepatitis C virus and attenuates the antiviral action of interferon
-
McCartney, E. M.; Semendric, L.; Helbig, K. J.; Hinze, S.; Jones, B.; Weinman, S. A.; Beard, M. R. Alcohol metabolism increases the replication of hepatitis C virus and attenuates the antiviral action of interferon. J. Infect. Dis. 2008, 198, 1766-1775.
-
(2008)
J. Infect. Dis
, vol.198
, pp. 1766-1775
-
-
McCartney, E.M.1
Semendric, L.2
Helbig, K.J.3
Hinze, S.4
Jones, B.5
Weinman, S.A.6
Beard, M.R.7
-
18
-
-
74049115063
-
Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+
-
Seronello, S.; Ito, C.; Wakita, T.; Choi, J. Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+. J. Biol. Chem. 2010, 285, 845-854.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 845-854
-
-
Seronello, S.1
Ito, C.2
Wakita, T.3
Choi, J.4
-
19
-
-
34547674835
-
Redox regulation of hepatitis C in nonalcoholic and alcoholic liver
-
Seronello, S.; Sheikh, M. Y.; Choi, J. Redox regulation of hepatitis C in nonalcoholic and alcoholic liver. Free Radic. Biol. Med. 2007, 43, 869-882.
-
(2007)
Free Radic. Biol. Med
, vol.43
, pp. 869-882
-
-
Seronello, S.1
Sheikh, M.Y.2
Choi, J.3
-
20
-
-
33747312640
-
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures
-
Elaut, G.; Henkens, T.; Papeleu, P.; Snykers, S.; Vinken, M.; Vanhaecke, T.; Rogiers, V. Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. Curr. Drug Metab. 2006, 7, 629-660.
-
(2006)
Curr. Drug Metab
, vol.7
, pp. 629-660
-
-
Elaut, G.1
Henkens, T.2
Papeleu, P.3
Snykers, S.4
Vinken, M.5
Vanhaecke, T.6
Rogiers, V.7
-
21
-
-
84875685934
-
Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells
-
Hou, W.; Bukong, T. N.; Kodys, K.; Szabo, G. Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. Alcohol. Clin. Exp. Res. 2013, 37, 599-608.
-
(2013)
Alcohol. Clin. Exp. Res
, vol.37
, pp. 599-608
-
-
Hou, W.1
Bukong, T.N.2
Kodys, K.3
Szabo, G.4
-
22
-
-
84872148409
-
Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells
-
Bukong, T. N.; Hou, W.; Kodys, K.; Szabo, G. Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology 2013, 57, 70-80.
-
(2013)
Hepatology
, vol.57
, pp. 70-80
-
-
Bukong, T.N.1
Hou, W.2
Kodys, K.3
Szabo, G.4
-
23
-
-
34547913440
-
Cellular cofactors affecting hepatitis C virus infection and replication
-
Randall, G.; Panis, M.; Cooper, J. D.; Tellinghuisen, T. L.; Sukhodolets, K. E.; Pfeffer, S.; Landthaler, M.; Landgraf, P.; Kan, S.; Lindenbach, B. D.; et al. Cellular cofactors affecting hepatitis C virus infection and replication. Proc. Natl. Acad. Sci. USA 2007, 104, 12884-12889.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12884-12889
-
-
Randall, G.1
Panis, M.2
Cooper, J.D.3
Tellinghuisen, T.L.4
Sukhodolets, K.E.5
Pfeffer, S.6
Landthaler, M.7
Landgraf, P.8
Kan, S.9
Lindenbach, B.D.10
-
24
-
-
84909996208
-
Alcoholic and non-alcoholic steatohepatitis
-
Neuman, M. G.; French, S. W.; French, B. A.; Seitz, H. K.; Cohen, L. B.; Mueller, S.; Osna, N. A.; Kharbanda, K. K.; Seth, D.; Bautista, A.; et al. Alcoholic and non-alcoholic steatohepatitis. Exp. Mol. Pathol. 2014, 97, 492-510.
-
(2014)
Exp. Mol. Pathol
, vol.97
, pp. 492-510
-
-
Neuman, M.G.1
French, S.W.2
French, B.A.3
Seitz, H.K.4
Cohen, L.B.5
Mueller, S.6
Osna, N.A.7
Kharbanda, K.K.8
Seth, D.9
Bautista, A.10
-
25
-
-
84904746154
-
Ethanol affects hepatitis C pathogenesis: Humanized SCID Alb-upA mouse model
-
Osna, N. A.; Kharbanda, K. K.; Sun, Y.; Simpson, R. L.; Poluektova, L. E.; Ganesan, M.; Wisecarver, J. L.; Mercer, D. F. Ethanol affects hepatitis C pathogenesis: Humanized SCID Alb-upA mouse model. Biochem. Biophys. Res. Commun. 2014, 450, 773-776.
-
(2014)
Biochem. Biophys. Res. Commun
, vol.450
, pp. 773-776
-
-
Osna, N.A.1
Kharbanda, K.K.2
Sun, Y.3
Simpson, R.L.4
Poluektova, L.E.5
Ganesan, M.6
Wisecarver, J.L.7
Mercer, D.F.8
-
26
-
-
0037372134
-
Hepatitis C and alcohol: Interactions, outcomes, and implications
-
Bhattacharya, R.; Shuhart, M. C. Hepatitis C and alcohol: Interactions, outcomes, and implications. J. Clin. Gastroenterol. 2003, 36, 242-252.
-
(2003)
J. Clin. Gastroenterol
, vol.36
, pp. 242-252
-
-
Bhattacharya, R.1
Shuhart, M.C.2
-
27
-
-
17344367032
-
Effect of alcohol consumption on serum hepatitis C virus RNA and histological lesions in chronic hepatitis C
-
Pessione, F.; Degos, F.; Marcellin, P.; Duchatelle, V.; Njapoum, C.; Martinot-Peignoux, M.; Degott, C.; Valla, D.; Erlinger, S.; Rueff, B. Effect of alcohol consumption on serum hepatitis C virus RNA and histological lesions in chronic hepatitis C. Hepatology 1998, 27, 1717-1722.
-
(1998)
Hepatology
, vol.27
, pp. 1717-1722
-
-
Pessione, F.1
Degos, F.2
Marcellin, P.3
Duchatelle, V.4
Njapoum, C.5
Martinot-Peignoux, M.6
Degott, C.7
Valla, D.8
Erlinger, S.9
Rueff, B.10
-
28
-
-
25444502098
-
Alcohol has no effect on hepatitis C virus replication: A meta-analysis
-
Anand, B. S.; Thornby, J. Alcohol has no effect on hepatitis C virus replication: A meta-analysis. Gut 2005, 54, 1468-1472.
-
(2005)
Gut
, vol.54
, pp. 1468-1472
-
-
Anand, B.S.1
Thornby, J.2
-
29
-
-
22244447136
-
Efficient hepatitis C virus cell culture system: What a difference the host cell makes
-
Bartenschlager, R.; Pietschmann, T. Efficient hepatitis C virus cell culture system: What a difference the host cell makes. Proc. Natl. Acad. Sci. USA 2005, 102, 9739-9740.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9739-9740
-
-
Bartenschlager, R.1
Pietschmann, T.2
-
30
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-+B and IRF 3
-
Seth, R. B.; Sun, L.; Ea, C. K.; Chen, Z. J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-+B and IRF 3. Cell 2005, 122, 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
31
-
-
80052281413
-
Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus
-
Horner, S. M.; Liu, H. M.; Park, H. S.; Briley, J.; Gale, M., Jr. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc. Natl. Acad. Sci. USA 2011, 108, 14590-14595.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14590-14595
-
-
Horner, S.M.1
Liu, H.M.2
Park, H.S.3
Briley, J.4
Gale, M.5
-
32
-
-
84872396542
-
Innate immune responses in hepatitis C virus infection
-
Li, K.; Lemon, S. M. Innate immune responses in hepatitis C virus infection. Semin. Immunopathol. 2013, 35, 53-72.
-
(2013)
Semin. Immunopathol
, vol.35
, pp. 53-72
-
-
Li, K.1
Lemon, S.M.2
-
33
-
-
4344620814
-
The cytoplasmic "linker region" in toll-like receptor 3 controls receptor localization and signaling
-
Funami, K.; Matsumoto, M.; Oshiumi, H.; Akazawa, T.; Yamamoto, A.; Seya, T. The cytoplasmic "linker region" in toll-like receptor 3 controls receptor localization and signaling. Int. Immunol. 2004, 16, 1143-1154.
-
(2004)
Int. Immunol
, vol.16
, pp. 1143-1154
-
-
Funami, K.1
Matsumoto, M.2
Oshiumi, H.3
Akazawa, T.4
Yamamoto, A.5
Seya, T.6
-
34
-
-
56549116047
-
Toll-like receptor and RIG-I-like receptor signaling
-
Kawai, T.; Akira, S. Toll-like receptor and RIG-I-like receptor signaling. Ann. NY Acad. Sci. 2008, 1143, 1-20.
-
(2008)
Ann. NY Acad. Sci
, vol.1143
, pp. 1-20
-
-
Kawai, T.1
Akira, S.2
-
35
-
-
33947722603
-
TLR pathways and IFN-regulatory factors: To each its own
-
Colonna, M. TLR pathways and IFN-regulatory factors: To each its own. Eur. J. Immunol. 2007, 37, 306-309.
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 306-309
-
-
Colonna, M.1
-
36
-
-
20144389695
-
Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
-
Hornung, V.; Guenthner-Biller, M.; Bourquin, C.; Ablasser, A.; Schlee, M.; Uematsu, S.; Noronha, A.; Manoharan, M.; Akira, S.; de Fougerolles, A.; et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat. Med. 2005, 11, 263-270.
-
(2005)
Nat. Med
, vol.11
, pp. 263-270
-
-
Hornung, V.1
Guenthner-Biller, M.2
Bourquin, C.3
Ablasser, A.4
Schlee, M.5
Uematsu, S.6
Noronha, A.7
Manoharan, M.8
Akira, S.9
de Fougerolles, A.10
-
37
-
-
33747040825
-
Pattern recognition receptors: A contemporary view on liver diseases
-
Szabo, G.; Dolganiuc, A.; Mandrekar, P. Pattern recognition receptors: A contemporary view on liver diseases. Hepatology 2006, 44, 287-298.
-
(2006)
Hepatology
, vol.44
, pp. 287-298
-
-
Szabo, G.1
Dolganiuc, A.2
Mandrekar, P.3
-
38
-
-
46749128497
-
Hepatitis C and innate immunity: Recent advances
-
Szabo, G.; Dolganiuc, A. Hepatitis C and innate immunity: Recent advances. Clin. Liver Dis. 2008, 12, 675-692.
-
(2008)
Clin. Liver Dis
, vol.12
, pp. 675-692
-
-
Szabo, G.1
Dolganiuc, A.2
-
39
-
-
17644372733
-
Ipc: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
-
Liu, Y. J. Ipc: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 2005, 23, 275-306.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 275-306
-
-
Liu, Y.J.1
-
40
-
-
84880955471
-
Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance
-
Qashqari, H.; Al-Mars, A.; Chaudhary, A.; Abuzenadah, A.; Damanhouri, G.; Alqahtani, M.; Mahmoud, M.; El Sayed Zaki, M.; Fatima, K.; Qadri, I. Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance. Infect. Genet. Evol. 2013, 19, 113-119.
-
(2013)
Infect. Genet. Evol
, vol.19
, pp. 113-119
-
-
Qashqari, H.1
Al-Mars, A.2
Chaudhary, A.3
Abuzenadah, A.4
Damanhouri, G.5
Alqahtani, M.6
Mahmoud, M.7
El Sayed Zaki, M.8
Fatima, K.9
Qadri, I.10
-
41
-
-
44349109098
-
Interferon signaling and treatment outcome in chronic hepatitis C
-
Sarasin-Filipowicz, M.; Oakeley, E. J.; Duong, F. H.; Christen, V.; Terracciano, L.; Filipowicz, W.; Heim, M. H. Interferon signaling and treatment outcome in chronic hepatitis C. Proc. Natl. Acad. Sci. USA 2008, 105, 7034-7039.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7034-7039
-
-
Sarasin-Filipowicz, M.1
Oakeley, E.J.2
Duong, F.H.3
Christen, V.4
Terracciano, L.5
Filipowicz, W.6
Heim, M.H.7
-
42
-
-
34548525772
-
Expression of toll-like receptors in chronic hepatitis C virus infection
-
Sato, K.; Ishikawa, T.; Okumura, A.; Yamauchi, T.; Sato, S.; Ayada, M.; Matsumoto, E.; Hotta, N.; Oohashi, T.; Fukuzawa, Y.; et al. Expression of toll-like receptors in chronic hepatitis C virus infection. J. Gastroenterol. Hepatol. 2007, 22, 1627-1632.
-
(2007)
J. Gastroenterol. Hepatol
, vol.22
, pp. 1627-1632
-
-
Sato, K.1
Ishikawa, T.2
Okumura, A.3
Yamauchi, T.4
Sato, S.5
Ayada, M.6
Matsumoto, E.7
Hotta, N.8
Oohashi, T.9
Fukuzawa, Y.10
-
43
-
-
14544280209
-
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
-
Li, K.; Foy, E.; Ferreon, J. C.; Nakamura, M.; Ferreon, A. C.; Ikeda, M.; Ray, S. C.; Gale, M., Jr.; Lemon, S. M. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc. Natl. Acad. Sci. USA 2005, 102, 2992-2997.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2992-2997
-
-
Li, K.1
Foy, E.2
Ferreon, J.C.3
Nakamura, M.4
Ferreon, A.C.5
Ikeda, M.6
Ray, S.C.7
Gale, M.8
Lemon, S.M.9
-
44
-
-
23944485662
-
Evasion of intracellular host defence by hepatitis C virus
-
Gale, M., Jr.; Foy, E. M. Evasion of intracellular host defence by hepatitis C virus. Nature 2005, 436, 939-945.
-
(2005)
Nature
, vol.436
, pp. 939-945
-
-
Gale, M.1
Foy, E.M.2
-
45
-
-
84862514366
-
Interaction of hepatitis C virus proteins with pattern recognition receptors
-
Imran, M.; Waheed, Y.; Manzoor, S.; Bilal, M.; Ashraf, W.; Ali, M.; Ashraf, M. Interaction of hepatitis C virus proteins with pattern recognition receptors. Virol. J. 2012, doi: 10. 1186/1743-422X-9-126.
-
(2012)
Virol. J
-
-
Imran, M.1
Waheed, Y.2
Manzoor, S.3
Bilal, M.4
Ashraf, W.5
Ali, M.6
Ashraf, M.7
-
46
-
-
44949154435
-
Interferon-beta is activated by hepatitis C virus NS5B and inhibited by NS4A, NS4B, AND NS5A
-
Moriyama, M.; Kato, N.; Otsuka, M.; Shao, R. X.; Taniguchi, H.; Kawabe, T.; Omata, M. Interferon-beta is activated by hepatitis C virus NS5B and inhibited by NS4A, NS4B, AND NS5A. Hepatol. Int. 2007, 1, 302-310.
-
(2007)
Hepatol. Int
, vol.1
, pp. 302-310
-
-
Moriyama, M.1
Kato, N.2
Otsuka, M.3
Shao, R.X.4
Taniguchi, H.5
Kawabe, T.6
Omata, M.7
-
47
-
-
73449145993
-
Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells
-
Chang, S.; Kodys, K.; Szabo, G. Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells. Hepatology 2010, 51, 35-42.
-
(2010)
Hepatology
, vol.51
, pp. 35-42
-
-
Chang, S.1
Kodys, K.2
Szabo, G.3
-
48
-
-
33644631594
-
Reduced expression and functional impairment of toll-like receptor 2 on dendritic cells in chronic hepatitis C virus infection
-
Yakushijin, T.; Kanto, T.; Inoue, M.; Oze, T.; Miyazaki, M.; Itose, I.; Miyatake, H.; Sakakibara, M.; Kuzushita, N.; Hiramatsu, N.; et al. Reduced expression and functional impairment of toll-like receptor 2 on dendritic cells in chronic hepatitis C virus infection. Hepatol. Res. 2006, 34, 156-162.
-
(2006)
Hepatol. Res
, vol.34
, pp. 156-162
-
-
Yakushijin, T.1
Kanto, T.2
Inoue, M.3
Oze, T.4
Miyazaki, M.5
Itose, I.6
Miyatake, H.7
Sakakibara, M.8
Kuzushita, N.9
Hiramatsu, N.10
-
49
-
-
22644432777
-
Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection
-
Szabo, G.; Dolganiuc, A. Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection. Immunobiology 2005, 210, 237-247.
-
(2005)
Immunobiology
, vol.210
, pp. 237-247
-
-
Szabo, G.1
Dolganiuc, A.2
-
50
-
-
33750826035
-
Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection
-
Dolganiuc, A.; Chang, S.; Kodys, K.; Mandrekar, P.; Bakis, G.; Cormier, M.; Szabo, G. Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection. J. Immunol. 2006, 177, 6758-6768.
-
(2006)
J. Immunol
, vol.177
, pp. 6758-6768
-
-
Dolganiuc, A.1
Chang, S.2
Kodys, K.3
Mandrekar, P.4
Bakis, G.5
Cormier, M.6
Szabo, G.7
-
51
-
-
77953286248
-
Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles
-
Hoffmann, M.; Zeisel, M. B.; Jilg, N.; Paranhos-Baccala, G.; Stoll-Keller, F.; Wakita, T.; Hafkemeyer, P.; Blum, H. E.; Barth, H.; Henneke, P.; et al. Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles. J. Innate Immun. 2009, 1, 446-454.
-
(2009)
J. Innate Immun
, vol.1
, pp. 446-454
-
-
Hoffmann, M.1
Zeisel, M.B.2
Jilg, N.3
Paranhos-Baccala, G.4
Stoll-Keller, F.5
Wakita, T.6
Hafkemeyer, P.7
Blum, H.E.8
Barth, H.9
Henneke, P.10
-
52
-
-
34548418137
-
Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins
-
Chang, S.; Dolganiuc, A.; Szabo, G. Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. J. Leukoc. Biol. 2007, 82, 479-487.
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 479-487
-
-
Chang, S.1
Dolganiuc, A.2
Szabo, G.3
-
53
-
-
39549097752
-
Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function
-
Shiina, M.; Rehermann, B. Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function. Hepatology 2008, 47, 385-395.
-
(2008)
Hepatology
, vol.47
, pp. 385-395
-
-
Shiina, M.1
Rehermann, B.2
-
54
-
-
84900385674
-
Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression
-
Stone, A. E.; Mitchell, A.; Brownell, J.; Miklin, D. J.; Golden-Mason, L.; Polyak, S. J.; Gale, M. J., Jr.; Rosen, H. R. Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression. PLOS ONE 2014, 9, e95627.
-
(2014)
PLOS ONE
, vol.9
-
-
Stone, A.E.1
Mitchell, A.2
Brownell, J.3
Miklin, D.J.4
Golden-Mason, L.5
Polyak, S.J.6
Gale, M.J.7
Rosen, H.R.8
-
55
-
-
43049183612
-
Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication
-
Broering, R.; Wu, J.; Meng, Z.; Hilgard, P.; Lu, M.; Trippler, M.; Szczeponek, A.; Gerken, G.; Schlaak, J. F. Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication. J. Hepatol. 2008, 48, 914-922.
-
(2008)
J. Hepatol
, vol.48
, pp. 914-922
-
-
Broering, R.1
Wu, J.2
Meng, Z.3
Hilgard, P.4
Lu, M.5
Trippler, M.6
Szczeponek, A.7
Gerken, G.8
Schlaak, J.F.9
-
56
-
-
79955579228
-
HCV-related proteins activate kupffer cells isolated from human liver tissues
-
Hosomura, N.; Kono, H.; Tsuchiya, M.; Ishii, K.; Ogiku, M.; Matsuda, M.; Fujii, H. HCV-related proteins activate kupffer cells isolated from human liver tissues. Dig. Dis. Sci. 2011, 56, 1057-1064.
-
(2011)
Dig. Dis. Sci
, vol.56
, pp. 1057-1064
-
-
Hosomura, N.1
Kono, H.2
Tsuchiya, M.3
Ishii, K.4
Ogiku, M.5
Matsuda, M.6
Fujii, H.7
-
57
-
-
84876871333
-
IL-1beta production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease
-
Negash, A. A.; Ramos, H. J.; Crochet, N.; Lau, D. T.; Doehle, B.; Papic, N.; Delker, D. A.; Jo, J.; Bertoletti, A.; Hagedorn, C. H.; et al. IL-1beta production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease. PLOS Pathog. 2013, 9, e1003330.
-
(2013)
PLOS Pathog
, vol.9
-
-
Negash, A.A.1
Ramos, H.J.2
Crochet, N.3
Lau, D.T.4
Doehle, B.5
Papic, N.6
Delker, D.A.7
Jo, J.8
Bertoletti, A.9
Hagedorn, C.H.10
-
58
-
-
84896494832
-
Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner
-
Fletcher, N. F.; Sutaria, R.; Jo, J.; Barnes, A.; Blahova, M.; Meredith, L. W.; Cosset, F. L.; Curbishley, S. M.; Adams, D. H.; Bertoletti, A.; et al. Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner. Hepatology 2014, 59, 1320-1330.
-
(2014)
Hepatology
, vol.59
, pp. 1320-1330
-
-
Fletcher, N.F.1
Sutaria, R.2
Jo, J.3
Barnes, A.4
Blahova, M.5
Meredith, L.W.6
Cosset, F.L.7
Curbishley, S.M.8
Adams, D.H.9
Bertoletti, A.10
-
59
-
-
84879464300
-
Multi-step regulation of interferon induction by hepatitis C virus
-
Oshiumi, H.; Funami, K.; Aly, H. H.; Matsumoto, M.; Seya, T. Multi-step regulation of interferon induction by hepatitis C virus. Arch. Immunol. Ther. Exp. 2013, 61, 127-138.
-
(2013)
Arch. Immunol. Ther. Exp
, vol.61
, pp. 127-138
-
-
Oshiumi, H.1
Funami, K.2
Aly, H.H.3
Matsumoto, M.4
Seya, T.5
-
60
-
-
84984572492
-
Regulation of host innate immunity by hepatitis C virus: Crosstalk between hepatocyte and NK/DC
-
Park, S. J.; Hahn, Y. S. Regulation of host innate immunity by hepatitis C virus: Crosstalk between hepatocyte and NK/DC. Rev. Infect. 2010, 1, 151-157.
-
(2010)
Rev. Infect
, vol.1
, pp. 151-157
-
-
Park, S.J.1
Hahn, Y.S.2
-
61
-
-
84885060120
-
Emerging concepts in immunity to hepatitis C virus infection
-
Rosen, H. R. Emerging concepts in immunity to hepatitis C virus infection. J. Clin. Investig. 2013, 123, 4121-4130.
-
(2013)
J. Clin. Investig
, vol.123
, pp. 4121-4130
-
-
Rosen, H.R.1
-
62
-
-
80051712972
-
Hepatitis C virus nonstructural 5A protein inhibits lipopolysaccharidemediated apoptosis of hepatocytes by decreasing expression of toll-like receptor 4
-
Tamura, R.; Kanda, T.; Imazeki, F.; Wu, S.; Nakamoto, S.; Tanaka, T.; Arai, M.; Fujiwara, K.; Saito, K.; Roger, T.; et al. Hepatitis C virus nonstructural 5A protein inhibits lipopolysaccharidemediated apoptosis of hepatocytes by decreasing expression of toll-like receptor 4. J. Infect. Dis. 2011, 204, 793-801.
-
(2011)
J. Infect. Dis
, vol.204
, pp. 793-801
-
-
Tamura, R.1
Kanda, T.2
Imazeki, F.3
Wu, S.4
Nakamoto, S.5
Tanaka, T.6
Arai, M.7
Fujiwara, K.8
Saito, K.9
Roger, T.10
-
63
-
-
0028798823
-
Role of STAT2 in the alpha interferon signaling pathway
-
Leung, S.; Qureshi, S. A.; Kerr, I. M.; Darnell, J. E., Jr.; Stark, G. R. Role of STAT2 in the alpha interferon signaling pathway. Mol. Cell. Biol. 1995, 15, 1312-1317.
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 1312-1317
-
-
Leung, S.1
Qureshi, S.A.2
Kerr, I.M.3
Darnell, J.E.4
Stark, G.R.5
-
64
-
-
0029869176
-
The SH2 domains of STAT1 and STAT2 mediate multiple interactions in the transduction of IFN-alpha signals
-
Gupta, S.; Yan, H.; Wong, L. H.; Ralph, S.; Krolewski, J.; Schindler, C. The SH2 domains of STAT1 and STAT2 mediate multiple interactions in the transduction of IFN-alpha signals. EMBO J. 1996, 15, 1075-1084.
-
(1996)
EMBO J
, vol.15
, pp. 1075-1084
-
-
Gupta, S.1
Yan, H.2
Wong, L.H.3
Ralph, S.4
Krolewski, J.5
Schindler, C.6
-
65
-
-
0034658696
-
Complex roles of STAT1 in regulating gene expression
-
Ramana, C. V.; Chatterjee-Kishore, M.; Nguyen, H.; Stark, G. R. Complex roles of STAT1 in regulating gene expression. Oncogene 2000, 19, 2619-2627.
-
(2000)
Oncogene
, vol.19
, pp. 2619-2627
-
-
Ramana, C.V.1
Chatterjee-Kishore, M.2
Nguyen, H.3
Stark, G.R.4
-
66
-
-
58849139353
-
A phosphorylation-acetylation switch regulates STAT1 signaling
-
Kramer, O. H.; Knauer, S. K.; Greiner, G.; Jandt, E.; Reichardt, S.; Guhrs, K. H.; Stauber, R. H.; Bohmer, F. D.; Heinzel, T. A phosphorylation-acetylation switch regulates STAT1 signaling. Genes Dev. 2009, 23, 223-235.
-
(2009)
Genes Dev
, vol.23
, pp. 223-235
-
-
Kramer, O.H.1
Knauer, S.K.2
Greiner, G.3
Jandt, E.4
Reichardt, S.5
Guhrs, K.H.6
Stauber, R.H.7
Bohmer, F.D.8
Heinzel, T.9
-
67
-
-
36749069393
-
Interferons at age 50: Past, current and future impact on biomedicine
-
Borden, E. C.; Sen, G. C.; Uze, G.; Silverman, R. H.; Ransohoff, R. M.; Foster, G. R.; Stark, G. R. Interferons at age 50: Past, current and future impact on biomedicine. Nat. Rev. Drug Discov. 2007, 6, 975-990.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 975-990
-
-
Borden, E.C.1
Sen, G.C.2
Uze, G.3
Silverman, R.H.4
Ransohoff, R.M.5
Foster, G.R.6
Stark, G.R.7
-
68
-
-
78649708165
-
IL28B and the control of hepatitis C virus infection
-
Balagopal, A.; Thomas, D. L.; Thio, C. L. IL28B and the control of hepatitis C virus infection. Gastroenterology 2010, 139, 1865-1876.
-
(2010)
Gastroenterology
, vol.139
, pp. 1865-1876
-
-
Balagopal, A.1
Thomas, D.L.2
Thio, C.L.3
-
69
-
-
33748488244
-
Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain
-
Lin, W.; Kim, S. S.; Yeung, E.; Kamegaya, Y.; Blackard, J. T.; Kim, K. A.; Holtzman, M. J.; Chung, R. T. Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain. J. Virol. 2006, 80, 9226-9235.
-
(2006)
J. Virol
, vol.80
, pp. 9226-9235
-
-
Lin, W.1
Kim, S.S.2
Yeung, E.3
Kamegaya, Y.4
Blackard, J.T.5
Kim, K.A.6
Holtzman, M.J.7
Chung, R.T.8
-
70
-
-
84877790291
-
Hepatitis C virus targets the interferon-alpha JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes
-
Stevenson, N. J.; Bourke, N. M.; Ryan, E. J.; Binder, M.; Fanning, L.; Johnston, J. A.; Hegarty, J. E.; Long, A.; O'Farrelly, C. Hepatitis C virus targets the interferon-alpha JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes. FEBS Lett. 2013, 587, 1571-1578.
-
(2013)
FEBS Lett
, vol.587
, pp. 1571-1578
-
-
Stevenson, N.J.1
Bourke, N.M.2
Ryan, E.J.3
Binder, M.4
Fanning, L.5
Johnston, J.A.6
Hegarty, J.E.7
Long, A.8
O'Farrelly, C.9
-
71
-
-
84865086668
-
Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling
-
Kumthip, K.; Chusri, P.; Jilg, N.; Zhao, L.; Fusco, D. N.; Zhao, H.; Goto, K.; Cheng, D.; Schaefer, E. A.; Zhang, L.; et al. Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling. J. Virol. 2012, 86, 8581-8591.
-
(2012)
J. Virol
, vol.86
, pp. 8581-8591
-
-
Kumthip, K.1
Chusri, P.2
Jilg, N.3
Zhao, L.4
Fusco, D.N.5
Zhao, H.6
Goto, K.7
Cheng, D.8
Schaefer, E.A.9
Zhang, L.10
-
72
-
-
0037362931
-
IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3
-
Bode, J. G.; Ludwig, S.; Ehrhardt, C.; Albrecht, U.; Erhardt, A.; Schaper, F.; Heinrich, P. C.; Haussinger, D. IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3. FASEB J. 2003, 17, 488-490.
-
(2003)
FASEB J
, vol.17
, pp. 488-490
-
-
Bode, J.G.1
Ludwig, S.2
Ehrhardt, C.3
Albrecht, U.4
Erhardt, A.5
Schaper, F.6
Heinrich, P.C.7
Haussinger, D.8
-
73
-
-
33645984234
-
S-adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro
-
Duong, F. H.; Christen, V.; Filipowicz, M.; Heim, M. H. S-adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro. Hepatology 2006, 43, 796-806.
-
(2006)
Hepatology
, vol.43
, pp. 796-806
-
-
Duong, F.H.1
Christen, V.2
Filipowicz, M.3
Heim, M.H.4
-
74
-
-
77950605031
-
Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair
-
Duong, F. H.; Christen, V.; Lin, S.; Heim, M. H. Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair. Hepatology 2010, 51, 741-751.
-
(2010)
Hepatology
, vol.51
, pp. 741-751
-
-
Duong, F.H.1
Christen, V.2
Lin, S.3
Heim, M.H.4
-
75
-
-
0346100572
-
Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A
-
Duong, F. H.; Filipowicz, M.; Tripodi, M.; la Monica, N.; Heim, M. H. Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A. Gastroenterology 2004, 126, 263-277.
-
(2004)
Gastroenterology
, vol.126
, pp. 263-277
-
-
Duong, F.H.1
Filipowicz, M.2
Tripodi, M.3
la Monica, N.4
Heim, M.H.5
-
76
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda, K.; Yanai, H.; Negishi, H.; Asagiri, M.; Sato, M.; Mizutani, T.; Shimada, N.; Ohba, Y.; Takaoka, A.; Yoshida, N.; et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434, 772-777.
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
Shimada, N.7
Ohba, Y.8
Takaoka, A.9
Yoshida, N.10
-
77
-
-
79251632920
-
PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection
-
Ma, C. J.; Ni, L.; Zhang, Y.; Zhang, C. L.; Wu, X. Y.; Atia, A. N.; Thayer, P.; Moorman, J. P.; Yao, Z. Q. PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection. Immunology 2011, 132, 421-431.
-
(2011)
Immunology
, vol.132
, pp. 421-431
-
-
Ma, C.J.1
Ni, L.2
Zhang, Y.3
Zhang, C.L.4
Wu, X.Y.5
Atia, A.N.6
Thayer, P.7
Moorman, J.P.8
Yao, Z.Q.9
-
78
-
-
0033516497
-
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein
-
Taylor, D. R.; Shi, S. T.; Romano, P. R.; Barber, G. N.; Lai, M. M. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein. Science 1999, 285, 107-110.
-
(1999)
Science
, vol.285
, pp. 107-110
-
-
Taylor, D.R.1
Shi, S.T.2
Romano, P.R.3
Barber, G.N.4
Lai, M.M.5
-
79
-
-
0343924357
-
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
-
Gale, M. J., Jr.; Korth, M. J.; Tang, N. M.; Tan, S. L.; Hopkins, D. A.; Dever, T. E.; Polyak, S. J.; Gretch, D. R.; Katze, M. G. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 1997, 230, 217-227.
-
(1997)
Virology
, vol.230
, pp. 217-227
-
-
Gale, M.J.1
Korth, M.J.2
Tang, N.M.3
Tan, S.L.4
Hopkins, D.A.5
Dever, T.E.6
Polyak, S.J.7
Gretch, D.R.8
Katze, M.G.9
-
80
-
-
84870623251
-
DsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection
-
Dabo, S.; Meurs, E. F. DsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection. Viruses 2012, 4, 2598-2635.
-
(2012)
Viruses
, vol.4
, pp. 2598-2635
-
-
Dabo, S.1
Meurs, E.F.2
-
81
-
-
84861330800
-
MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors
-
Castanier, C.; Zemirli, N.; Portier, A.; Garcin, D.; Bidere, N.; Vazquez, A.; Arnoult, D. MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors. BMC Biol. 2012, doi: 10. 1186/1741-7007-10-44.
-
(2012)
BMC Biol
-
-
Castanier, C.1
Zemirli, N.2
Portier, A.3
Garcin, D.4
Bidere, N.5
Vazquez, A.6
Arnoult, D.7
-
82
-
-
70449725290
-
Negative regulation of MAVS-mediated innate immune response by PSMA7
-
Jia, Y.; Song, T.; Wei, C.; Ni, C.; Zheng, Z.; Xu, Q.; Ma, H.; Li, L.; Zhang, Y.; He, X.; et al. Negative regulation of MAVS-mediated innate immune response by PSMA7. J. Immunol. 2009, 183, 4241-4248.
-
(2009)
J. Immunol
, vol.183
, pp. 4241-4248
-
-
Jia, Y.1
Song, T.2
Wei, C.3
Ni, C.4
Zheng, Z.5
Xu, Q.6
Ma, H.7
Li, L.8
Zhang, Y.9
He, X.10
-
83
-
-
80055065839
-
Hepatitis C virus reveals a novel early control in acute immune response
-
Arnaud, N.; Dabo, S.; Akazawa, D.; Fukasawa, M.; Shinkai-Ouchi, F.; Hugon, J.; Wakita, T.; Meurs, E. F. Hepatitis C virus reveals a novel early control in acute immune response. PLOS Pathog. 2011, 7, e1002289.
-
(2011)
PLOS Pathog
, vol.7
-
-
Arnaud, N.1
Dabo, S.2
Akazawa, D.3
Fukasawa, M.4
Shinkai-Ouchi, F.5
Hugon, J.6
Wakita, T.7
Meurs, E.F.8
-
84
-
-
84874116578
-
Innate immunity and HCV
-
Heim, M. H. Innate immunity and HCV. J. Hepatol. 2013, 58, 564-574.
-
(2013)
J. Hepatol
, vol.58
, pp. 564-574
-
-
Heim, M.H.1
-
85
-
-
0030752667
-
Hepatitis C virus: Epidemiology and transmission
-
Heintges, T.; Wands, J. R. Hepatitis C virus: Epidemiology and transmission. Hepatology 1997, 26, 521-526.
-
(1997)
Hepatology
, vol.26
, pp. 521-526
-
-
Heintges, T.1
Wands, J.R.2
-
86
-
-
79251482742
-
Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
-
Petrasek, J.; Dolganiuc, A.; Csak, T.; Nath, B.; Hritz, I.; Kodys, K.; Catalano, D.; Kurt-Jones, E.; Mandrekar, P.; Szabo, G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology 2011, 53, 649-660.
-
(2011)
Hepatology
, vol.53
, pp. 649-660
-
-
Petrasek, J.1
Dolganiuc, A.2
Csak, T.3
Nath, B.4
Hritz, I.5
Kodys, K.6
Catalano, D.7
Kurt-Jones, E.8
Mandrekar, P.9
Szabo, G.10
-
87
-
-
4043177671
-
Suppression of innate immunity by acute ethanol administration: A global perspective and a new mechanism beginning with inhibition of signaling through TLR3
-
Pruett, S. B.; Schwab, C.; Zheng, Q.; Fan, R. Suppression of innate immunity by acute ethanol administration: A global perspective and a new mechanism beginning with inhibition of signaling through TLR3. J. Immunol. 2004, 173, 2715-2724.
-
(2004)
J. Immunol
, vol.173
, pp. 2715-2724
-
-
Pruett, S.B.1
Schwab, C.2
Zheng, Q.3
Fan, R.4
-
88
-
-
19344375848
-
Acute exposure to ethanol affects toll-like receptor signaling and subsequent responses: An overview of recent studies
-
Pruett, S. B.; Zheng, Q.; Fan, R.; Matthews, K.; Schwab, C. Acute exposure to ethanol affects toll-like receptor signaling and subsequent responses: An overview of recent studies. Alcohol 2004, 33, 235-239.
-
(2004)
Alcohol
, vol.33
, pp. 235-239
-
-
Pruett, S.B.1
Zheng, Q.2
Fan, R.3
Matthews, K.4
Schwab, C.5
-
89
-
-
84872366958
-
Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating kupffer cells and stellate cells to produce interleukin-10 in mice
-
Byun, J. S.; Suh, Y. G.; Yi, H. S.; Lee, Y. S.; Jeong, W. I. Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating kupffer cells and stellate cells to produce interleukin-10 in mice. J. Hepatol. 2013, 58, 342-349.
-
(2013)
J. Hepatol
, vol.58
, pp. 342-349
-
-
Byun, J.S.1
Suh, Y.G.2
Yi, H.S.3
Lee, Y.S.4
Jeong, W.I.5
-
90
-
-
80053370841
-
Inhibition of TLR8-and TLR4-induced type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes
-
Pang, M.; Bala, S.; Kodys, K.; Catalano, D.; Szabo, G. Inhibition of TLR8-and TLR4-induced type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol. 2011, doi: 10. 1186/1471-2172-12-55.
-
(2011)
BMC Immunol
-
-
Pang, M.1
Bala, S.2
Kodys, K.3
Catalano, D.4
Szabo, G.5
-
91
-
-
66549093053
-
Toll-like receptors and their role in gastrointestinal disease
-
Testro, A. G.; Visvanathan, K. Toll-like receptors and their role in gastrointestinal disease. J. Gastroenterol. Hepatol. 2009, 24, 943-954.
-
(2009)
J. Gastroenterol. Hepatol
, vol.24
, pp. 943-954
-
-
Testro, A.G.1
Visvanathan, K.2
-
92
-
-
70249091176
-
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes
-
Mandrekar, P.; Bala, S.; Catalano, D.; Kodys, K.; Szabo, G. The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. J. Immunol. 2009, 183, 1320-1327.
-
(2009)
J. Immunol
, vol.183
, pp. 1320-1327
-
-
Mandrekar, P.1
Bala, S.2
Catalano, D.3
Kodys, K.4
Szabo, G.5
-
93
-
-
79953277497
-
TLRs, alcohol, HCV, and tumorigenesis
-
Machida, K. TLRs, alcohol, HCV, and tumorigenesis. Gastroenterol. Res. Pract. 2010, doi: 10. 1155/2010/518674.
-
(2010)
Gastroenterol. Res. Pract
-
-
Machida, K.1
-
94
-
-
70349567521
-
Alcoholic liver disease and hepatitis C: A frequently underestimated combination
-
Mueller, S.; Millonig, G.; Seitz, H. K. Alcoholic liver disease and hepatitis C: A frequently underestimated combination. World J. Gastroenterol. 2009, 15, 3462-3471.
-
(2009)
World J. Gastroenterol
, vol.15
, pp. 3462-3471
-
-
Mueller, S.1
Millonig, G.2
Seitz, H.K.3
-
95
-
-
60849102149
-
Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog
-
Machida, K.; Tsukamoto, H.; Mkrtchyan, H.; Duan, L.; Dynnyk, A.; Liu, H. M.; Asahina, K.; Govindarajan, S.; Ray, R.; Ou, J. H.; et al. Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog. Proc. Natl. Acad. Sci. USA 2009, 106, 1548-1553.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1548-1553
-
-
Machida, K.1
Tsukamoto, H.2
Mkrtchyan, H.3
Duan, L.4
Dynnyk, A.5
Liu, H.M.6
Asahina, K.7
Govindarajan, S.8
Ray, R.9
Ou, J.H.10
-
96
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya, K.; Fujie, H.; Shintani, Y.; Yotsuyanagi, H.; Tsutsumi, T.; Ishibashi, K.; Matsuura, Y.; Kimura, S.; Miyamura, T.; Koike, K. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat. Med. 1998, 4, 1065-1067.
-
(1998)
Nat. Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
Yotsuyanagi, H.4
Tsutsumi, T.5
Ishibashi, K.6
Matsuura, Y.7
Kimura, S.8
Miyamura, T.9
Koike, K.10
-
97
-
-
84919774560
-
Pathogenesis of alcoholic liver disease: Role of oxidative metabolism
-
Ceni, E.; Mello, T.; Galli, A. Pathogenesis of alcoholic liver disease: Role of oxidative metabolism. World J. Gastroenterol. 2014, 20, 17756-17772.
-
(2014)
World J. Gastroenterol
, vol.20
, pp. 17756-17772
-
-
Ceni, E.1
Mello, T.2
Galli, A.3
-
98
-
-
29244434123
-
Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells
-
Plumlee, C. R.; Lazaro, C. A.; Fausto, N.; Polyak, S. J. Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. Virol. J. 2005, doi: 10. 1186/1743-422X-2-89.
-
(2005)
Virol. J
-
-
Plumlee, C.R.1
Lazaro, C.A.2
Fausto, N.3
Polyak, S.J.4
-
99
-
-
0034662145
-
Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: Differential regulation by acute ethanol via a protein kinase C-dependent mechanism
-
Nguyen, V. A.; Chen, J.; Hong, F.; Ishac, E. J.; Gao, B. Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: Differential regulation by acute ethanol via a protein kinase C-dependent mechanism. Biochem. J. 2000, 349, 427-434.
-
(2000)
Biochem. J
, vol.349
, pp. 427-434
-
-
Nguyen, V.A.1
Chen, J.2
Hong, F.3
Ishac, E.J.4
Gao, B.5
-
100
-
-
30944453568
-
Ethanol metabolism alters interferon gamma signaling in recombinant HEPG2 cells
-
Osna, N. A.; Clemens, D. L.; Donohue, T. M., Jr. Ethanol metabolism alters interferon gamma signaling in recombinant HEPG2 cells. Hepatology 2005, 42, 1109-1117.
-
(2005)
Hepatology
, vol.42
, pp. 1109-1117
-
-
Osna, N.A.1
Clemens, D.L.2
Donohue, T.M.3
-
101
-
-
84905321988
-
CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
-
Osna, N. A.; Donohue, T. M., Jr. CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy. Subcell. Biochem. 2013, 67, 177-197.
-
(2013)
Subcell. Biochem
, vol.67
, pp. 177-197
-
-
Osna, N.A.1
Donohue, T.M.2
-
102
-
-
84868211262
-
Circulating micrornas in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
-
Bala, S.; Petrasek, J.; Mundkur, S.; Catalano, D.; Levin, I.; Ward, J.; Alao, H.; Kodys, K.; Szabo, G. Circulating micrornas in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology 2012, 56, 1946-1957.
-
(2012)
Hepatology
, vol.56
, pp. 1946-1957
-
-
Bala, S.1
Petrasek, J.2
Mundkur, S.3
Catalano, D.4
Levin, I.5
Ward, J.6
Alao, H.7
Kodys, K.8
Szabo, G.9
-
103
-
-
84880797948
-
Exosomes mediate the cell-to-cell transmission of IFN-alpha-induced antiviral activity
-
Li, J.; Liu, K.; Liu, Y.; Xu, Y.; Zhang, F.; Yang, H.; Liu, J.; Pan, T.; Chen, J.; Wu, M.; et al. Exosomes mediate the cell-to-cell transmission of IFN-alpha-induced antiviral activity. Nat. Immunol. 2013, 14, 793-803.
-
(2013)
Nat. Immunol
, vol.14
, pp. 793-803
-
-
Li, J.1
Liu, K.2
Liu, Y.3
Xu, Y.4
Zhang, F.5
Yang, H.6
Liu, J.7
Pan, T.8
Chen, J.9
Wu, M.10
-
104
-
-
0033854171
-
Ethanol inhibition: The humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization
-
Encke, J.; Wands, J. R. Ethanol inhibition: The humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization. Alcohol. Clin. Exp. Res. 2000, 24, 1063-1069.
-
(2000)
Alcohol. Clin. Exp. Res
, vol.24
, pp. 1063-1069
-
-
Encke, J.1
Wands, J.R.2
-
105
-
-
0032212215
-
Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model
-
Encke, J.; zu Putlitz, J.; Geissler, M.; Wands, J. R. Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model. J. Immunol. 1998, 161, 4917-4923.
-
(1998)
J. Immunol
, vol.161
, pp. 4917-4923
-
-
Encke, J.1
zu Putlitz, J.2
Geissler, M.3
Wands, J.R.4
-
106
-
-
84860463134
-
Early growth response-1 contributes to steatosis development after acute ethanol administration
-
Donohue, T. M., Jr.; Osna, N. A.; Trambly, C. S.; Whitaker, N. P.; Thomes, P. G.; Todero, S. L.; Davis, J. S. Early growth response-1 contributes to steatosis development after acute ethanol administration. Alcohol. Clin. Exp. Res. 2012, 36, 759-767.
-
(2012)
Alcohol. Clin. Exp. Res
, vol.36
, pp. 759-767
-
-
Donohue, T.M.1
Osna, N.A.2
Trambly, C.S.3
Whitaker, N.P.4
Thomes, P.G.5
Todero, S.L.6
Davis, J.S.7
-
107
-
-
65449181938
-
Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells
-
Osna, N. A.; White, R. L.; Thiele, G. M.; Donohue, T. M., Jr. Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells. Hepatology 2009, 49, 1308-1315.
-
(2009)
Hepatology
, vol.49
, pp. 1308-1315
-
-
Osna, N.A.1
White, R.L.2
Thiele, G.M.3
Donohue, T.M.4
-
108
-
-
33846421564
-
Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells
-
Osna, N. A.; White, R. L.; Todero, S.; McVicker, B. L.; Thiele, G. M.; Clemens, D. L.; Tuma, D. J.; Donohue, T. M., Jr. Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells. Hepatology 2007, 45, 53-61.
-
(2007)
Hepatology
, vol.45
, pp. 53-61
-
-
Osna, N.A.1
White, R.L.2
Todero, S.3
McVicker, B.L.4
Thiele, G.M.5
Clemens, D.L.6
Tuma, D.J.7
Donohue, T.M.8
-
109
-
-
84904757279
-
Mode of oral ethanol feeding affects liver oxidative stress levels and methylation status: Study on NS5A-transgenic mice
-
Osna, N.; McVicker, B.; Poluektova, L.; Ganesan, M.; Kharbanda, K. Mode of oral ethanol feeding affects liver oxidative stress levels and methylation status: Study on NS5A-transgenic mice. Int. J. Biochem. Res. Rev. 2014, 4, 344-357.
-
(2014)
Int. J. Biochem. Res. Rev
, vol.4
, pp. 344-357
-
-
Osna, N.1
McVicker, B.2
Poluektova, L.3
Ganesan, M.4
Kharbanda, K.5
-
110
-
-
84920945807
-
Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir
-
Donaldson, E. F.; Harrington, P. R.; O'Rear, J. J.; Naeger, L. K. Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir. Hepatology 2015, 61, 56-65.
-
(2015)
Hepatology
, vol.61
, pp. 56-65
-
-
Donaldson, E.F.1
Harrington, P.R.2
O'Rear, J.J.3
Naeger, L.K.4
|