Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes

BMC Immunology

Volumn 12, Issue , 2011, Pages

  Pang, Maoyin ^a,b   Bala, Shashi ^a   Kodys, Karen ^a   Catalano, Donna ^a   Szabo, Gyongyi ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Acute; Alcohol; Chronic; Ifn ; Il 10; Tnf alpha

Indexed keywords

ALCOHOL; INTERFERON; INTERLEUKIN 10; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CL 075; LIPOPOLYSACCHARIDE; QUINOLINE DERIVATIVE; THIAZOLE DERIVATIVE; TLR4 PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CELL VIABILITY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONOCYTE; PROTEIN EXPRESSION; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY;

CELLS, CULTURED; ETHANOL; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERFERON TYPE I; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; QUINOLINES; THIAZOLES; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053370841     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-12-55     Document Type: Article

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