메뉴 건너뛰기




Volumn 14, Issue 8, 2013, Pages 793-803

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; MESSENGER RNA; STAT1 PROTEIN;

EID: 84880797948     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2647     Document Type: Article
Times cited : (455)

References (52)
  • 1
    • 36749069393 scopus 로고    scopus 로고
    • Interferons at age 50: Past, current and future impact on biomedicine
    • Borden, E.C. et al. Interferons at age 50: Past, current and future impact on biomedicine. Nat. Rev. Drug Discov. 6, 975-990 (2007).
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 975-990
    • Borden, E.C.1
  • 2
    • 61549137854 scopus 로고    scopus 로고
    • Interferons and their use in persistent viral infections
    • Chevaliez, S. & Pawlotsky, J.M. Interferons and their use in persistent viral infections. Handb. Exp. Pharmacol. 189, 203-241 (2009).
    • (2009) Handb. Exp. Pharmacol. , vol.189 , pp. 203-241
    • Chevaliez, S.1    Pawlotsky, J.M.2
  • 3
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall, R.E. & Goodbourn, S. Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol. 89, 1-47 (2008).
    • (2008) J. Gen. Virol. , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 4
    • 0017660534 scopus 로고
    • Interferon-induced transfer of viral resistance between animal cells
    • Blalock, J.E. & Baron, S. Interferon-induced transfer of viral resistance between animal cells. Nature 269, 422-425 (1977).
    • (1977) Nature , vol.269 , pp. 422-425
    • Blalock, J.E.1    Baron, S.2
  • 5
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • Théry, C., Ostrowski, M. & Segura, E. Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol. 9, 581-593 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 581-593
    • Théry, C.1    Ostrowski, M.2    Segura, E.3
  • 6
    • 84860218631 scopus 로고    scopus 로고
    • Intercellular communication: Diverse structures for exchange of genetic information
    • Mittelbrunn, M. & Sanchez-Madrid, F. Intercellular communication: Diverse structures for exchange of genetic information. Nat. Rev. Mol. Cell Biol. 13, 328-335 (2012).
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 328-335
    • Mittelbrunn, M.1    Sanchez-Madrid, F.2
  • 7
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi, H. et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9, 654-659 (2007).
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1
  • 8
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog, J. et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 10, 1470-1476 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1470-1476
    • Skog, J.1
  • 9
    • 79955070767 scopus 로고    scopus 로고
    • Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
    • Mittelbrunn, M. et al. Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat. Commun. 2, 282 (2011).
    • (2011) Nat. Commun. , vol.2 , Issue.282
    • Mittelbrunn, M.1
  • 10
    • 84862908547 scopus 로고    scopus 로고
    • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
    • Montecalvo, A. et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 119, 756-766 (2012).
    • (2012) Blood , vol.119 , pp. 756-766
    • Montecalvo, A.1
  • 11
    • 78650553841 scopus 로고    scopus 로고
    • Human tumor virus utilizes exosomes for intercellular communication
    • Meckes, D.G. Jr. et al. Human tumor virus utilizes exosomes for intercellular communication. Proc. Natl. Acad. Sci. USA 107, 20370-20375 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 20370-20375
    • Meckes Jr., D.G.1
  • 12
    • 77950889558 scopus 로고    scopus 로고
    • Functional delivery of viral miRNAs via exosomes
    • Pegtel, D.M. et al. Functional delivery of viral miRNAs via exosomes. Proc. Natl. Acad. Sci. USA 107, 6328-6333 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 6328-6333
    • Pegtel, D.M.1
  • 13
    • 0020041099 scopus 로고
    • Lack of interferon-induced transfer of viral resistance against murine leukemia virus or poliovirus in cocultivated cells
    • Mozes, L.W. Lack of interferon-induced transfer of viral resistance against murine leukemia virus or poliovirus in cocultivated cells. Virology 116, 359-362 (1982).
    • (1982) Virology , vol.116 , pp. 359-362
    • Mozes, L.W.1
  • 17
    • 77953295897 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus replication by MyD88 involves accelerated degradation of pregenomic RNA and nuclear retention of pre-S/S RNAs
    • Li, J. et al. Inhibition of hepatitis B virus replication by MyD88 involves accelerated degradation of pregenomic RNA and nuclear retention of pre-S/S RNAs. J. Virol. 84, 6387-6399 (2010).
    • (2010) J. Virol. , vol.84 , pp. 6387-6399
    • Li, J.1
  • 18
    • 71849094369 scopus 로고    scopus 로고
    • Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice
    • Hiraga, N. et al. Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice. J. Hepatol. 51, 1046-1054 (2009).
    • (2009) J. Hepatol. , vol.51 , pp. 1046-1054
    • Hiraga, N.1
  • 19
    • 79958127932 scopus 로고    scopus 로고
    • Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice
    • Lutgehetmann, M. et al. Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice. Gastroenterology 140, 2074-2083 (2011).
    • (2011) Gastroenterology , vol.140 , pp. 2074-2083
    • Lutgehetmann, M.1
  • 20
    • 84873311551 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase impairs interferon-(-induced STA T activation through inhibition of importin-(5 and protein kinase C-d
    • Chen, J. et al. Hepatitis B virus polymerase impairs interferon-(-induced STA T activation through inhibition of importin-(5 and protein kinase C.-d. Hepatology 57, 470-482 (2013).
    • (2013) Hepatology , vol.57 , pp. 470-482
    • Chen, J.1
  • 21
    • 39549097751 scopus 로고    scopus 로고
    • Liver: An organ with predominant innate immunity
    • Gao, B., Jeong, W.I. & Tian, Z. Liver: An organ with predominant innate immunity. Hepatology 47, 729-736 (2008).
    • (2008) Hepatology , vol.47 , pp. 729-736
    • Gao, B.1    Jeong, W.I.2    Tian, Z.3
  • 23
    • 36749058339 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1
    • Wu, M. et al. Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J. Gen. Virol. 88, 3260-3269 (2007).
    • (2007) J. Gen. Virol. , vol.88 , pp. 3260-3269
    • Wu, M.1
  • 24
    • 0037108818 scopus 로고    scopus 로고
    • Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
    • Yang, P.L., Althage, A., Chung, J. & Chisari, F.V. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection. Proc. Natl. Acad. Sci. USA 99, 13825-13830 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13825-13830
    • Yang, P.L.1    Althage, A.2    Chung, J.3    Chisari, F.V.4
  • 25
    • 77952008630 scopus 로고    scopus 로고
    • Adoptive transfer of ex vivo HO-1 modified bone marrow-derived macrophages prevents liver ischemia and reperfusion injury
    • Ke, B. et al. Adoptive transfer of ex vivo HO-1 modified bone marrow-derived macrophages prevents liver ischemia and reperfusion injury. Mol. Ther. 18, 1019-1025 (2010).
    • (2010) Mol. Ther. , vol.18 , pp. 1019-1025
    • Ke, B.1
  • 26
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • Trajkovic, K. et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 319, 1244-1247 (2008).
    • (2008) Science , vol.319 , pp. 1244-1247
    • Trajkovic, K.1
  • 27
    • 77952920881 scopus 로고    scopus 로고
    • Secretory mechanisms and intercellular transfer of microRNAs in living cells
    • Kosaka, N. et al. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J. Biol. Chem. 285, 17442-17452 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 17442-17452
    • Kosaka, N.1
  • 28
    • 84867653559 scopus 로고    scopus 로고
    • Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity
    • Dreux, M. et al. Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host Microbe 12, 558-570 (2012).
    • (2012) Cell Host Microbe , vol.12 , pp. 558-570
    • Dreux, M.1
  • 29
    • 67349114201 scopus 로고    scopus 로고
    • Acid sphingomyelinase activity triggers microparticle release from glial cells
    • Bianco, F. et al. Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J. 28, 1043-1054 (2009).
    • (2009) EMBO J. , vol.28 , pp. 1043-1054
    • Bianco, F.1
  • 30
    • 0033526089 scopus 로고    scopus 로고
    • Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis
    • Zhang, J., Reedy, M.C., Hannun, Y.A. & Obeid, L.M. Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis. J. Cell Biol. 145, 99-108 (1999).
    • (1999) J. Cell Biol. , vol.145 , pp. 99-108
    • Zhang, J.1    Reedy, M.C.2    Hannun, Y.A.3    Obeid, L.M.4
  • 31
    • 79953136097 scopus 로고    scopus 로고
    • Rab27a and Rab27b control different steps of the exosome secretion pathway
    • Ostrowski, M. et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat. Cell Biol 12, 19-30 (2010).
    • (2010) Nat. Cell Biol , vol.12 , pp. 19-30
    • Ostrowski, M.1
  • 33
    • 84855855145 scopus 로고    scopus 로고
    • Microvesicles and viral infection
    • Meckes, D.G. Jr. & Raab-Traub, N. Microvesicles and viral infection. J. Virol. 85, 12844-12854 (2011).
    • (2011) J. Virol. , vol.85 , pp. 12844-12854
    • Meckes Jr., D.G.1    Raab-Traub, N.2
  • 34
    • 1642308939 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus replication by APOBEC3G
    • Turelli, P., Mangeat, B., Jost, S., Vianin, S. & Trono, D. Inhibition of hepatitis B virus replication by APOBEC3G. Science 303, 1829 (2004).
    • (2004) Science , vol.303 , pp. 1829
    • Turelli, P.1    Mangeat, B.2    Jost, S.3    Vianin, S.4    Trono, D.5
  • 35
    • 81055157995 scopus 로고    scopus 로고
    • PKR-dependent mechanisms of interferon-α for inhibiting hepatitis B virus replication
    • Park, I.H., Baek, K.W., Cho, E.Y. & Ahn, B.Y. PKR-dependent mechanisms of interferon-α for inhibiting hepatitis B virus replication. Mol. Cells 32, 167-172 (2011).
    • (2011) Mol. Cells , vol.32 , pp. 167-172
    • Park, I.H.1    Baek, K.W.2    Cho, E.Y.3    Ahn, B.Y.4
  • 36
    • 63649092087 scopus 로고    scopus 로고
    • Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
    • Keller, S. et al. Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes. Cancer Lett. 278, 73-81 (2009).
    • (2009) Cancer Lett. , vol.278 , pp. 73-81
    • Keller, S.1
  • 37
    • 29144451985 scopus 로고    scopus 로고
    • Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus
    • Weiss, S.R. & Navas-Martin, S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol. Mol. Biol. Rev. 69, 635-664 (2005).
    • (2005) Microbiol. Mol. Biol. Rev. , vol.69 , pp. 635-664
    • Weiss, S.R.1    Navas-Martin, S.2
  • 38
    • 68149157175 scopus 로고    scopus 로고
    • Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
    • DuPage, M., Dooley, A.L. & Jacks, T. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat. Protoc. 4, 1064-1072 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 1064-1072
    • DuPage, M.1    Dooley, A.L.2    Jacks, T.3
  • 39
    • 77952127743 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection
    • Takahashi, K. et al. Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection. Proc. Natl. Acad. Sci. USA 107, 7431-7436 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7431-7436
    • Takahashi, K.1
  • 40
    • 79955481749 scopus 로고    scopus 로고
    • Exosomes as intercellular signalosomes and pharmacological effectors
    • Record, M., Subra, C., Silvente-Poirot, S. & Poirot, M. Exosomes as intercellular signalosomes and pharmacological effectors. Biochem. Pharmacol. 81, 1171-1182 (2011).
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 1171-1182
    • Record, M.1    Subra, C.2    Silvente-Poirot, S.3    Poirot, M.4
  • 41
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings, D.J., Ciaudo, C., Erhardt, M. & Voinnet, O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat. Cell Biol. 11, 1143-1149 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 42
    • 58149517753 scopus 로고    scopus 로고
    • Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells
    • Khatua, A.K., Taylor, H.E., Hildreth, J.E. & Popik, W. Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells. J. Virol. 83, 512-521 (2009).
    • (2009) J. Virol. , vol.83 , pp. 512-521
    • Khatua, A.K.1    Taylor, H.E.2    Hildreth, J.E.3    Popik, W.4
  • 43
    • 84869118771 scopus 로고    scopus 로고
    • The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy
    • Chang, J., Block, T.M. & Guo, J.T. The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy. Antiviral Res. 96, 405-413 (2012).
    • (2012) Antiviral Res. , vol.96 , pp. 405-413
    • Chang, J.1    Block, T.M.2    Guo, J.T.3
  • 44
    • 78650666385 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells
    • Mao, R. et al. Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells. J. Virol. 85, 1048-1057 (2011).
    • (2011) J. Virol. , vol.85 , pp. 1048-1057
    • Mao, R.1
  • 45
    • 79954576940 scopus 로고    scopus 로고
    • Roles of TIPE2 in hepatitis B virus-induced hepatic inflammation in humans and mice
    • Xi, W. et al. Roles of TIPE2 in hepatitis B virus-induced hepatic inflammation in humans and mice. Mol. Immunol. 48, 1203-1208 (2011).
    • (2011) Mol. Immunol. , vol.48 , pp. 1203-1208
    • Xi, W.1
  • 46
    • 84871484827 scopus 로고    scopus 로고
    • The broad-spectrum antiviral functions of IFIT and IFITM proteins
    • Diamond, M.S. & Farzan, M. The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat. Rev. Immunol. 13, 46-57 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 46-57
    • Diamond, M.S.1    Farzan, M.2
  • 47
    • 0023339694 scopus 로고
    • An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
    • Pinkert, C.A., Ornitz, D.M., Brinster, R.L. & Palmiter, R.D. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev. 1, 268-276 (1987).
    • (1987) Genes Dev. , vol.1 , pp. 268-276
    • Pinkert, C.A.1    Ornitz, D.M.2    Brinster, R.L.3    Palmiter, R.D.4
  • 48
    • 0028120907 scopus 로고
    • The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor
    • Zhang, D.E., Hetherington, C.J., Chen, H.M. & Tenen, D.G. The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol. Cell. Biol. 14, 373-381 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 373-381
    • Zhang, D.E.1    Hetherington, C.J.2    Chen, H.M.3    Tenen, D.G.4
  • 49
    • 0033575335 scopus 로고    scopus 로고
    • Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene
    • Fadel, B.M., Boutet, S.C. & Quertermous, T. Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene. J. Biol. Chem. 274, 20376-20383 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 20376-20383
    • Fadel, B.M.1    Boutet, S.C.2    Quertermous, T.3
  • 50
    • 0025963002 scopus 로고
    • The Human leukemia-cell line, Thp-1-A multifaceted model for the study of monocyte-macrophage differentiation
    • Auwerx, J. The Human leukemia-cell line, Thp-1-a multifaceted model for the study of monocyte-macrophage differentiation. Experientia 47, 22-31 (1991).
    • (1991) Experientia , vol.47 , pp. 22-31
    • Auwerx, J.1
  • 51
    • 44649185201 scopus 로고    scopus 로고
    • Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H
    • Köck, J. & Blum, H.E. Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H. J. Gen. Virol. 89, 1184-1191 (2008).
    • (2008) J. Gen. Virol. , vol.89 , pp. 1184-1191
    • Köck, J.1    Blum, H.E.2
  • 52
    • 80051822117 scopus 로고    scopus 로고
    • Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies
    • Liu, W. et al. Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies. Proteomics 11, 3556-3564 (2011). Diseases
    • (2011) Proteomics , vol.11 , pp. 3556-3564
    • Liu, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.