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Volumn 15, Issue 28, 2009, Pages 3462-3471

Alcoholic liver disease and hepatitis C: A frequently underestimated combination

Author keywords

Alcoholic liver disease; Chronic hepatitis C; Cirrhosis; Fibrosis; Hepatocellular carcinoma; Iron accumulation; Reactive oxygen species; Steatohepatitis; Steatosis

Indexed keywords

ACETALDEHYDE; ALCOHOL; BETA CAROTENE; CYTOCHROME P450 2E1; FERROPORTIN; HEPCIDIN; INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; IRON; ISONIAZID; METHOTREXATE; PARACETAMOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RETINOL; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN;

EID: 70349567521     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.3462     Document Type: Review
Times cited : (121)

References (141)
  • 1
    • 0032451389 scopus 로고    scopus 로고
    • Alcoholic liver disease: Proposed recommendations for the American College of Gastroenterology
    • McCullough AJ, O'Connor JF. Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology. Am J Gastroenterol 1998; 93: 2022-2036
    • (1998) Am J Gastroenterol , vol.93 , pp. 2022-2036
    • McCullough, A.J.1    O'Connor, J.F.2
  • 2
    • 0242633858 scopus 로고    scopus 로고
    • Alcoholic liver disease
    • Feldman M, Friedman LS, Sleisenger MH, editors, Philadelphia: Saunders
    • Maher JJ. Alcoholic liver disease. In: Feldman M, Friedman LS, Sleisenger MH, editors. Gastrointestinal and Liver Disease Vol II. Philadelphia: Saunders, 2002: 1375-1391
    • (2002) Gastrointestinal and Liver Disease , vol.2 , pp. 1375-1391
    • Maher, J.J.1
  • 5
    • 70349571901 scopus 로고    scopus 로고
    • Jahrbuch Sucht 2007. Geesthacht: Neuland Verlagsgesellschaft mbH, 2007
    • Jahrbuch Sucht 2007. Geesthacht: Neuland Verlagsgesellschaft mbH, 2007
  • 6
    • 0033916804 scopus 로고    scopus 로고
    • Epidemiology of hepatitis C: Geographic differences and temporal trends
    • Wasley A, Alter MJ. Epidemiology of hepatitis C: geographic differences and temporal trends. Semin Liver Dis 2000; 20: 1-16
    • (2000) Semin Liver Dis , vol.20 , pp. 1-16
    • Wasley, A.1    Alter, M.J.2
  • 8
    • 34547932626 scopus 로고    scopus 로고
    • Mechanisms of synergy between alcohol and hepatitis C virus
    • Singal AK, Anand BS. Mechanisms of synergy between alcohol and hepatitis C virus. J Clin Gastroenterol 2007; 41: 761-772
    • (2007) J Clin Gastroenterol , vol.41 , pp. 761-772
    • Singal, A.K.1    Anand, B.S.2
  • 9
    • 37349077859 scopus 로고    scopus 로고
    • Alcohol-induced hepatitis: Pathophysiology and treatment
    • Diehl AM, Hayashy N, Manns MP, Sauerbruch T, editors, Dordrecht-Boston-London: Cluver Academic Publisher
    • Seitz HK, Becker P. Alcohol-induced hepatitis: pathophysiology and treatment. In: Diehl AM, Hayashy N, Manns MP, Sauerbruch T, editors. Chronic hepatitis: metabolic, cholestatic, viral und autoimmun. Dordrecht-Boston-London: Cluver Academic Publisher, 2007: 16-31
    • (2007) Chronic hepatitis: Metabolic, cholestatic, viral und autoimmun , pp. 16-31
    • Seitz, H.K.1    Becker, P.2
  • 10
    • 0028998145 scopus 로고
    • Clinical outcomes after transfusion-associated hepatitis C
    • Tong MJ, el-Farra NS, Reikes AR, Co RL. Clinical outcomes after transfusion-associated hepatitis C. N Engl J Med 1995; 332: 1463-1466
    • (1995) N Engl J Med , vol.332 , pp. 1463-1466
    • Tong, M.J.1    el-Farra, N.S.2    Reikes, A.R.3    Co, R.L.4
  • 11
    • 0033932001 scopus 로고    scopus 로고
    • Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome
    • Alter HJ, Seeff LB. Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome. Semin Liver Dis 2000; 20: 17-35
    • (2000) Semin Liver Dis , vol.20 , pp. 17-35
    • Alter, H.J.1    Seeff, L.B.2
  • 12
    • 0016861504 scopus 로고
    • Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse
    • Lelbach WK. Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse. Ann N Y Acad Sci 1975; 252: 85-105
    • (1975) Ann N Y Acad Sci , vol.252 , pp. 85-105
    • Lelbach, W.K.1
  • 13
    • 2642673699 scopus 로고
    • Les problemes nutritionelles de la societe industrielle
    • Pequignot G. Les problemes nutritionelles de la societe industrielle. La vie medicale en Canada francais 1974: 3: 216-255
    • (1974) La vie medicale en Canada francais , vol.3 , pp. 216-255
    • Pequignot, G.1
  • 14
    • 3042910782 scopus 로고    scopus 로고
    • Role of nutrition in the treatment of alcoholic liver disease
    • Arroyo V, Bosch J, Bruguera M, Rodes J, Sanchez-Tapia J, editors, Barcelona: Masson
    • Halsted C. Role of nutrition in the treatment of alcoholic liver disease. In: Arroyo V, Bosch J, Bruguera M, Rodes J, Sanchez-Tapia J, editors. Treatment of liver diseases. Barcelona: Masson, 1999: 221-232
    • (1999) Treatment of liver diseases , pp. 221-232
    • Halsted, C.1
  • 15
    • 0036288123 scopus 로고    scopus 로고
    • Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?
    • Nair S, Mason A, Eason J, Loss G, Perrillo RP. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology 2002; 36: 150-155
    • (2002) Hepatology , vol.36 , pp. 150-155
    • Nair, S.1    Mason, A.2    Eason, J.3    Loss, G.4    Perrillo, R.P.5
  • 16
    • 0042034405 scopus 로고    scopus 로고
    • Ethanol toxicity and nutritional status
    • Kotsonis F, Mackey M, editors, 2nd ed. London, New York: Taylor and Francis
    • Seitz HK, Suter P. Ethanol toxicity and nutritional status. In: Kotsonis F, Mackey M, editors. Nutritional toxicology. 2nd ed. London, New York: Taylor and Francis, 2002: 122-154
    • (2002) Nutritional toxicology , pp. 122-154
    • Seitz, H.K.1    Suter, P.2
  • 17
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 update
    • Lieber CS. Alcohol and the liver: 1994 update. Gastroenterology 1994; 106: 1085-1105
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 18
  • 19
    • 0026545056 scopus 로고
    • Interaction of ethanol with beta-carotene: Delayed blood clearance and enhanced hepatotoxicity
    • Leo MA, Kim C, Lowe N, Lieber CS. Interaction of ethanol with beta-carotene: delayed blood clearance and enhanced hepatotoxicity. Hepatology 1992; 15: 883-891
    • (1992) Hepatology , vol.15 , pp. 883-891
    • Leo, M.A.1    Kim, C.2    Lowe, N.3    Lieber, C.S.4
  • 21
    • 0031573081 scopus 로고    scopus 로고
    • Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Wands JR. Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids. J Immunol 1997; 159: 5107-5113
    • (1997) J Immunol , vol.159 , pp. 5107-5113
    • Geissler, M.1    Gesien, A.2    Wands, J.R.3
  • 22
    • 0030473496 scopus 로고    scopus 로고
    • Effect of alcohol intake on the efficacy of interferon therapy in patients with chronic hepatitis C as evaluated by multivariate logistic regression analysis
    • Mochida S, Ohnishi K, Matsuo S, Kakihara K, Fujiwara K. Effect of alcohol intake on the efficacy of interferon therapy in patients with chronic hepatitis C as evaluated by multivariate logistic regression analysis. Alcohol Clin Exp Res 1996; 20: 371A-377A
    • (1996) Alcohol Clin Exp Res , vol.20
    • Mochida, S.1    Ohnishi, K.2    Matsuo, S.3    Kakihara, K.4    Fujiwara, K.5
  • 24
    • 0030460664 scopus 로고    scopus 로고
    • Chronic hepatitis C: Effect of alcohol on hepatitic activity and viral titre
    • Cromie SL, Jenkins PJ, Bowden DS, Dudley FJ. Chronic hepatitis C: effect of alcohol on hepatitic activity and viral titre. J Hepatol 1996; 25: 821-826
    • (1996) J Hepatol , vol.25 , pp. 821-826
    • Cromie, S.L.1    Jenkins, P.J.2    Bowden, D.S.3    Dudley, F.J.4
  • 26
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997; 349: 825-832
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 27
    • 0030800166 scopus 로고    scopus 로고
    • Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: A French survey of 6,664 patients. The Study Group for the Prevalence and the Epidemiology of Hepatitis C Virus
    • Roudot-Thoraval F, Bastie A, Pawlotsky JM, Dhumeaux D. Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: a French survey of 6,664 patients. The Study Group for the Prevalence and the Epidemiology of Hepatitis C Virus. Hepatology 1997; 26: 485-490
    • (1997) Hepatology , vol.26 , pp. 485-490
    • Roudot-Thoraval, F.1    Bastie, A.2    Pawlotsky, J.M.3    Dhumeaux, D.4
  • 29
    • 0031721879 scopus 로고    scopus 로고
    • Impact of alcohol on the histological and clinical progression of hepatitis C infection
    • Wiley TE, McCarthy M, Breidi L, McCarthy M, Layden TJ. Impact of alcohol on the histological and clinical progression of hepatitis C infection. Hepatology 1998; 28: 805-809
    • (1998) Hepatology , vol.28 , pp. 805-809
    • Wiley, T.E.1    McCarthy, M.2    Breidi, L.3    McCarthy, M.4    Layden, T.J.5
  • 30
    • 0031749109 scopus 로고    scopus 로고
    • Role of alcohol in the progression of liver disease caused by hepatitis C virus infection
    • Ostapowicz G, Watson KJ, Locarnini SA, Desmond PV. Role of alcohol in the progression of liver disease caused by hepatitis C virus infection. Hepatology 1998; 27: 1730-1735
    • (1998) Hepatology , vol.27 , pp. 1730-1735
    • Ostapowicz, G.1    Watson, K.J.2    Locarnini, S.A.3    Desmond, P.V.4
  • 32
    • 0033659649 scopus 로고    scopus 로고
    • The HCV National Register: Towards informing the natural history of hepatitis C infection in the UK
    • Harris HE, Ramsay ME, Heptonstall J, Soldan K, Eldridge KP. The HCV National Register: towards informing the natural history of hepatitis C infection in the UK. J Viral Hepat 2000; 7: 420-427
    • (2000) J Viral Hepat , vol.7 , pp. 420-427
    • Harris, H.E.1    Ramsay, M.E.2    Heptonstall, J.3    Soldan, K.4    Eldridge, K.P.5
  • 33
    • 37149016438 scopus 로고    scopus 로고
    • Natural history of factors influencing the severity of chronic HCV infection in HIV-HCV coinfected patients]
    • Roulot D, Vallet-Pichard A. [Natural history of factors influencing the severity of chronic HCV infection in HIV-HCV coinfected patients] Gastroenterol Clin Biol 2007; 31: 881-886
    • (2007) Gastroenterol Clin Biol , vol.31 , pp. 881-886
    • Roulot, D.1    Vallet-Pichard, A.2
  • 34
    • 35248828024 scopus 로고    scopus 로고
    • Documented rapid course of hepatic fibrosis between two biopsies in patients coinfected by HIV and HCV despite high CD4 cell count
    • Bonnard P, Lescure FX, Amiel C, Guiard-Schmid JB, Callard P, Gharakhanian S, Pialoux G. Documented rapid course of hepatic fibrosis between two biopsies in patients coinfected by HIV and HCV despite high CD4 cell count. J Viral Hepat 2007; 14: 806-811
    • (2007) J Viral Hepat , vol.14 , pp. 806-811
    • Bonnard, P.1    Lescure, F.X.2    Amiel, C.3    Guiard-Schmid, J.B.4    Callard, P.5    Gharakhanian, S.6    Pialoux, G.7
  • 36
    • 34248377706 scopus 로고    scopus 로고
    • Therapeutic issues in HIV/ HCV-coinfected patients
    • Sulkowski MS, Benhamou Y. Therapeutic issues in HIV/ HCV-coinfected patients. J Viral Hepat 2007; 14: 371-386
    • (2007) J Viral Hepat , vol.14 , pp. 371-386
    • Sulkowski, M.S.1    Benhamou, Y.2
  • 37
    • 33748508848 scopus 로고    scopus 로고
    • Is time to treat for HCV all the HIV/HCV coinfected hemophiliacs?
    • Franchini M. Is time to treat for HCV all the HIV/HCV coinfected hemophiliacs? Hematology 2006; 11: 209-213
    • (2006) Hematology , vol.11 , pp. 209-213
    • Franchini, M.1
  • 40
    • 33750591210 scopus 로고    scopus 로고
    • Clinical challenges and controversies in the management of HIV/HCV-coinfected individuals
    • Santana JL, Rodriguez-Medina JR, Rodriguez-Orengo JF. Clinical challenges and controversies in the management of HIV/HCV-coinfected individuals. P R Health Sci J 2004; 23: 35-40
    • (2004) P R Health Sci J , vol.23 , pp. 35-40
    • Santana, J.L.1    Rodriguez-Medina, J.R.2    Rodriguez-Orengo, J.F.3
  • 41
  • 43
    • 33645999692 scopus 로고    scopus 로고
    • Characteristics of HCV positive subjects referring to hospitals in Italy: A multicentre prevalence study on 6,999 cases
    • Stroffolini T, Sagnelli E, Mariano A, Craxi A, Almasio P. Characteristics of HCV positive subjects referring to hospitals in Italy: a multicentre prevalence study on 6,999 cases. J Viral Hepat 2006; 13: 351-354
    • (2006) J Viral Hepat , vol.13 , pp. 351-354
    • Stroffolini, T.1    Sagnelli, E.2    Mariano, A.3    Craxi, A.4    Almasio, P.5
  • 44
    • 33646250428 scopus 로고    scopus 로고
    • The natural history of hepatitis C virus (HCV) infection
    • Chen SL, Morgan TR. The natural history of hepatitis C virus (HCV) infection. Int J Med Sci 2006; 3: 47-52
    • (2006) Int J Med Sci , vol.3 , pp. 47-52
    • Chen, S.L.1    Morgan, T.R.2
  • 45
    • 33645058677 scopus 로고    scopus 로고
    • Park JS, Saraf N, Dieterich DT. HBV plus HCV, HCV plus HIV, HBV plus HIV. Curr Gastroenterol Rep 2006; 8: 67-74
    • Park JS, Saraf N, Dieterich DT. HBV plus HCV, HCV plus HIV, HBV plus HIV. Curr Gastroenterol Rep 2006; 8: 67-74
  • 48
    • 33644873326 scopus 로고    scopus 로고
    • Pathophysiology of portal hypertension in HCV-related cirrhosis. Putative role of assessment of portal pressure gradient in Peginterferon-treated patients
    • Ratti L, Pozzi M, Bosch J. Pathophysiology of portal hypertension in HCV-related cirrhosis. Putative role of assessment of portal pressure gradient in Peginterferon-treated patients. Dig Liver Dis 2005; 37: 886-893
    • (2005) Dig Liver Dis , vol.37 , pp. 886-893
    • Ratti, L.1    Pozzi, M.2    Bosch, J.3
  • 49
    • 25844439419 scopus 로고    scopus 로고
    • Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases
    • Colletta C, Smirne C, Fabris C, Toniutto P, Rapetti R, Minisini R, Pirisi M. Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases. Hepatology 2005; 42: 838-845
    • (2005) Hepatology , vol.42 , pp. 838-845
    • Colletta, C.1    Smirne, C.2    Fabris, C.3    Toniutto, P.4    Rapetti, R.5    Minisini, R.6    Pirisi, M.7
  • 51
    • 16644392018 scopus 로고    scopus 로고
    • Dieterich DT, Kontorinis N, Agarwal K. HIV/HCV coinfection in clinical practice. J Int Assoc Physicians AIDS Care (Chic Ill) 2004; 3 Suppl 1: S4-S14; quiz S16-S17
    • Dieterich DT, Kontorinis N, Agarwal K. HIV/HCV coinfection in clinical practice. J Int Assoc Physicians AIDS Care (Chic Ill) 2004; 3 Suppl 1: S4-S14; quiz S16-S17
  • 52
    • 17144433700 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) infections in alcoholics
    • Prakash O, Mason A, Luftig RB, Bautista AP. Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) infections in alcoholics. Front Biosci 2002; 7: e286-e300
    • (2002) Front Biosci , vol.7
    • Prakash, O.1    Mason, A.2    Luftig, R.B.3    Bautista, A.P.4
  • 56
    • 33644617560 scopus 로고    scopus 로고
    • The Hepatitis C Surveillance System Steering Committee. Past excessive alcohol consumption: A major determinant of severe liver disease among newly referred hepatitis C virus infected patients in hepatology reference centers, France, 2001
    • Delarocque-Astagneau E, Roudot-Thoraval F, Campese C, Desenclos JC, The Hepatitis C Surveillance System Steering Committee. Past excessive alcohol consumption: a major determinant of severe liver disease among newly referred hepatitis C virus infected patients in hepatology reference centers, France, 2001. Ann Epidemiol 2005; 15: 551-557
    • (2005) Ann Epidemiol , vol.15 , pp. 551-557
    • Delarocque-Astagneau, E.1    Roudot-Thoraval, F.2    Campese, C.3    Desenclos, J.C.4
  • 58
    • 33644762256 scopus 로고    scopus 로고
    • Hepatitis C screening and treatment outcomes in patients with substance use/ dependence disorders
    • Rifai MA, Moles JK, Lehman LP, Van der Linden BJ. Hepatitis C screening and treatment outcomes in patients with substance use/ dependence disorders. Psychosomatics 2006; 47: 112-121
    • (2006) Psychosomatics , vol.47 , pp. 112-121
    • Rifai, M.A.1    Moles, J.K.2    Lehman, L.P.3    Van der Linden, B.J.4
  • 60
    • 0038707215 scopus 로고    scopus 로고
    • Impact of moderate alcohol consumption on histological activity and fibrosis in patients with chronic hepatitis C, and specific influence of steatosis: A prospective study
    • Hezode C, Lonjon I, Roudot-Thoraval F, Pawlotsky JM, Zafrani ES, Dhumeaux D. Impact of moderate alcohol consumption on histological activity and fibrosis in patients with chronic hepatitis C, and specific influence of steatosis: a prospective study. Aliment Pharmacol Ther 2003; 17: 1031-1037
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 1031-1037
    • Hezode, C.1    Lonjon, I.2    Roudot-Thoraval, F.3    Pawlotsky, J.M.4    Zafrani, E.S.5    Dhumeaux, D.6
  • 61
    • 0029049451 scopus 로고
    • Relation between markers for viral hepatitis and clinical features of Japanese patients with hepatocellular carcinoma: Possible role of alcohol in promoting carcinogenesis
    • Matsuda Y, Amuro Y, Higashino K, Hada T, Yamamoto T, Fujikura M, Yamaguchi K, Shimomura S, Iijima H, Nakano T. Relation between markers for viral hepatitis and clinical features of Japanese patients with hepatocellular carcinoma: possible role of alcohol in promoting carcinogenesis. Hepatogastroenterology 1995; 42: 151-154
    • (1995) Hepatogastroenterology , vol.42 , pp. 151-154
    • Matsuda, Y.1    Amuro, Y.2    Higashino, K.3    Hada, T.4    Yamamoto, T.5    Fujikura, M.6    Yamaguchi, K.7    Shimomura, S.8    Iijima, H.9    Nakano, T.10
  • 62
    • 0031026902 scopus 로고    scopus 로고
    • Risk factors and the effect of interferon therapy in the development of hepatocellular carcinoma: A multivariate analysis in 343 patients
    • Kuwana K, Ichida T, Kamimura T, Ohkoshi S, Ogata N, Harada T, Endoh K, Asakura H. Risk factors and the effect of interferon therapy in the development of hepatocellular carcinoma: a multivariate analysis in 343 patients. J Gastroenterol Hepatol 1997; 12: 149-155
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. 149-155
    • Kuwana, K.1    Ichida, T.2    Kamimura, T.3    Ohkoshi, S.4    Ogata, N.5    Harada, T.6    Endoh, K.7    Asakura, H.8
  • 63
    • 0032960127 scopus 로고    scopus 로고
    • Casecontrol study on hepatitis C virus (HCV) as a risk factor for hepatocellular carcinoma: The role of HCV genotypes and the synergism with hepatitis B virus and alcohol. Brescia HCC Study
    • Tagger A, Donato F, Ribero ML, Chiesa R, Portera G, Gelatti U, Albertini A, Fasola M, Boffetta P, Nardi G. Casecontrol study on hepatitis C virus (HCV) as a risk factor for hepatocellular carcinoma: the role of HCV genotypes and the synergism with hepatitis B virus and alcohol. Brescia HCC Study. Int J Cancer 1999; 81: 695-699
    • (1999) Int J Cancer , vol.81 , pp. 695-699
    • Tagger, A.1    Donato, F.2    Ribero, M.L.3    Chiesa, R.4    Portera, G.5    Gelatti, U.6    Albertini, A.7    Fasola, M.8    Boffetta, P.9    Nardi, G.10
  • 64
    • 0034234726 scopus 로고    scopus 로고
    • Analysis of factors affecting the appearance of hepatocellular carcinoma in patients with chronic hepatitis C. A long term follow-up study after histologic diagnosis
    • Aizawa Y, Shibamoto Y, Takagi I, Zeniya M, Toda G. Analysis of factors affecting the appearance of hepatocellular carcinoma in patients with chronic hepatitis C. A long term follow-up study after histologic diagnosis. Cancer 2000; 89: 53-59
    • (2000) Cancer , vol.89 , pp. 53-59
    • Aizawa, Y.1    Shibamoto, Y.2    Takagi, I.3    Zeniya, M.4    Toda, G.5
  • 65
    • 0033669792 scopus 로고    scopus 로고
    • Clinical significance of hepatitis C virus infection to alcoholics with cirrhosis in Korea
    • Kwon SY, Ahn MS, Chang HJ. Clinical significance of hepatitis C virus infection to alcoholics with cirrhosis in Korea. J Gastroenterol Hepatol 2000; 15: 1282-1286
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 1282-1286
    • Kwon, S.Y.1    Ahn, M.S.2    Chang, H.J.3
  • 66
    • 0033932394 scopus 로고    scopus 로고
    • Effect of alcohol consumption on the progression of hepatitis C virus infection and risk of hepatocellular carcinoma in Japanese patients
    • Khan KN, Yatsuhashi H. Effect of alcohol consumption on the progression of hepatitis C virus infection and risk of hepatocellular carcinoma in Japanese patients. Alcohol Alcohol 2000; 35: 286-295
    • (2000) Alcohol Alcohol , vol.35 , pp. 286-295
    • Khan, K.N.1    Yatsuhashi, H.2
  • 69
    • 29244434123 scopus 로고    scopus 로고
    • Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells
    • Plumlee CR, Lazaro CA, Fausto N, Polyak SJ. Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. Virol J 2005; 2: 89
    • (2005) Virol J , vol.2 , pp. 89
    • Plumlee, C.R.1    Lazaro, C.A.2    Fausto, N.3    Polyak, S.J.4
  • 71
    • 0026733835 scopus 로고
    • Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism
    • Hardardottir I, Doerrler W, Feingold KR, Grunfeld C. Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism. Biochem Biophys Res Commun 1992; 186: 237-243
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 237-243
    • Hardardottir, I.1    Doerrler, W.2    Feingold, K.R.3    Grunfeld, C.4
  • 72
    • 0023220709 scopus 로고
    • Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo
    • Feingold KR, Grunfeld C. Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo. J Clin Invest 1987; 80: 184-190
    • (1987) J Clin Invest , vol.80 , pp. 184-190
    • Feingold, K.R.1    Grunfeld, C.2
  • 73
    • 0028382594 scopus 로고
    • Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: Synergy among TNF, IL-6, and IL-1
    • Nachiappan V, Curtiss D, Corkey BE, Kilpatrick L. Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: synergy among TNF, IL-6, and IL-1. Shock 1994; 1: 123-129
    • (1994) Shock , vol.1 , pp. 123-129
    • Nachiappan, V.1    Curtiss, D.2    Corkey, B.E.3    Kilpatrick, L.4
  • 75
    • 0032185432 scopus 로고    scopus 로고
    • II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
    • Thurman RG. II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol 1998; 275: G605-G611
    • (1998) Am J Physiol , vol.275
    • Thurman, R.G.1
  • 76
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000; 343: 1467-1476
    • (2000) N Engl J Med , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 77
    • 0035834684 scopus 로고    scopus 로고
    • Stabilization of tumor necrosis factor alpha mRNA by chronic ethanol: Role of A + U-rich elements and p38 mitogen-activated protein kinase signaling pathway
    • Kishore R, McMullen MR, Nagy LE. Stabilization of tumor necrosis factor alpha mRNA by chronic ethanol: role of A + U-rich elements and p38 mitogen-activated protein kinase signaling pathway. J Biol Chem 2001; 276: 41930-41937
    • (2001) J Biol Chem , vol.276 , pp. 41930-41937
    • Kishore, R.1    McMullen, M.R.2    Nagy, L.E.3
  • 78
    • 0037177899 scopus 로고    scopus 로고
    • Chronic ethanol increases lipopolysaccharide-stimulated Egr-1 expression in RAW 264.7 macrophages: Contribution to enhanced tumor necrosis factor alpha production
    • Shi L, Kishore R, McMullen MR, Nagy LE. Chronic ethanol increases lipopolysaccharide-stimulated Egr-1 expression in RAW 264.7 macrophages: contribution to enhanced tumor necrosis factor alpha production. J Biol Chem 2002; 277: 14777-14785
    • (2002) J Biol Chem , vol.277 , pp. 14777-14785
    • Shi, L.1    Kishore, R.2    McMullen, M.R.3    Nagy, L.E.4
  • 80
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel T. Oxidant signals and oxidative stress. Curr Opin Cell Biol 2003; 15: 247-254
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 247-254
    • Finkel, T.1
  • 81
    • 33645804223 scopus 로고    scopus 로고
    • Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding
    • Thakur V, Pritchard MT, McMullen MR, Nagy LE. Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding. Am J Physiol Gastrointest Liver Physiol 2006; 290: G998-G1007
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Thakur, V.1    Pritchard, M.T.2    McMullen, M.R.3    Nagy, L.E.4
  • 82
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 83
    • 24144496133 scopus 로고    scopus 로고
    • Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice
    • You M, Considine RV, Leone TC, Kelly DP, Crabb DW. Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice. Hepatology 2005; 42: 568-577
    • (2005) Hepatology , vol.42 , pp. 568-577
    • You, M.1    Considine, R.V.2    Leone, T.C.3    Kelly, D.P.4    Crabb, D.W.5
  • 84
    • 0030586328 scopus 로고    scopus 로고
    • Activation by acetaldehyde of the promoter of the mouse alpha2(I) collagen gene when transfected into rat activated stellate cells
    • Anania FA, Potter JJ, Rennie-Tankersley L, Mezey E. Activation by acetaldehyde of the promoter of the mouse alpha2(I) collagen gene when transfected into rat activated stellate cells. Arch Biochem Biophys 1996; 331: 187-193
    • (1996) Arch Biochem Biophys , vol.331 , pp. 187-193
    • Anania, F.A.1    Potter, J.J.2    Rennie-Tankersley, L.3    Mezey, E.4
  • 85
    • 0037115736 scopus 로고    scopus 로고
    • Acetaldehyde stimulates the activation of latent transforming growth factor-beta1 and induces expression of the type II receptor of the cytokine in rat cultured hepatic stellate cells
    • Chen A. Acetaldehyde stimulates the activation of latent transforming growth factor-beta1 and induces expression of the type II receptor of the cytokine in rat cultured hepatic stellate cells. Biochem J 2002; 368: 683-693
    • (2002) Biochem J , vol.368 , pp. 683-693
    • Chen, A.1
  • 87
    • 34547118090 scopus 로고    scopus 로고
    • Molecular mechanisms of alcohol-mediated carcinogenesis
    • Seitz HK, Stickel F. Molecular mechanisms of alcohol-mediated carcinogenesis. Nat Rev Cancer 2007; 7: 599-612
    • (2007) Nat Rev Cancer , vol.7 , pp. 599-612
    • Seitz, H.K.1    Stickel, F.2
  • 88
    • 33845927120 scopus 로고    scopus 로고
    • Alcohol, oxidative stress and free radical damage
    • Albano E. Alcohol, oxidative stress and free radical damage. Proc Nutr Soc 2006; 65: 278-290
    • (2006) Proc Nutr Soc , vol.65 , pp. 278-290
    • Albano, E.1
  • 89
    • 3042739680 scopus 로고    scopus 로고
    • Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis
    • Frank A, Seitz HK, Bartsch H, Frank N, Nair J. Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis. Carcinogenesis 2004; 25: 1027-1031
    • (2004) Carcinogenesis , vol.25 , pp. 1027-1031
    • Frank, A.1    Seitz, H.K.2    Bartsch, H.3    Frank, N.4    Nair, J.5
  • 92
    • 0036023302 scopus 로고    scopus 로고
    • Oxidative stress EPR measurement in human liver by radical-probe technique. Correlation with etiology, histology and cell proliferation
    • Valgimigli M, Valgimigli L, Trere D, Gaiani S, Pedulli GF, Gramantieri L, Bolondi L. Oxidative stress EPR measurement in human liver by radical-probe technique. Correlation with etiology, histology and cell proliferation. Free Radic Res 2002; 36: 939-948
    • (2002) Free Radic Res , vol.36 , pp. 939-948
    • Valgimigli, M.1    Valgimigli, L.2    Trere, D.3    Gaiani, S.4    Pedulli, G.F.5    Gramantieri, L.6    Bolondi, L.7
  • 94
    • 0037371816 scopus 로고    scopus 로고
    • Oxidants and antioxidants in alcohol-induced liver disease
    • Arteel GE. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003; 124: 778-790
    • (2003) Gastroenterology , vol.124 , pp. 778-790
    • Arteel, G.E.1
  • 95
    • 0036017180 scopus 로고    scopus 로고
    • Ethanol, oxidative stress, and cytokine-induced liver cell injury
    • Hoek JB, Pastorino JG. Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 2002; 27: 63-68
    • (2002) Alcohol , vol.27 , pp. 63-68
    • Hoek, J.B.1    Pastorino, J.G.2
  • 96
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM, Weinman SA. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002; 122: 366-375
    • (2002) Gastroenterology , vol.122 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6    Weinman, S.A.7
  • 97
    • 0035859871 scopus 로고    scopus 로고
    • Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B
    • Gong G, Waris G, Tanveer R, Siddiqui A. Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci USA 2001; 98: 9599-9604
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9599-9604
    • Gong, G.1    Waris, G.2    Tanveer, R.3    Siddiqui, A.4
  • 98
    • 0034954325 scopus 로고    scopus 로고
    • Effects of alcohol consumption on indices of iron stores and of iron stores on alcohol intake markers
    • Whitfield JB, Zhu G, Heath AC, Powell And LW, Martin NG. Effects of alcohol consumption on indices of iron stores and of iron stores on alcohol intake markers. Alcohol Clin Exp Res 2001; 25: 1037-1045
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1037-1045
    • Whitfield, J.B.1    Zhu, G.2    Heath, A.C.3    Powell And, L.W.4    Martin, N.G.5
  • 102
    • 33748310762 scopus 로고    scopus 로고
    • Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
    • Zhuge J, Cederbaum AI. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1. Free Radic Biol Med 2006; 41: 1100-1112
    • (2006) Free Radic Biol Med , vol.41 , pp. 1100-1112
    • Zhuge, J.1    Cederbaum, A.I.2
  • 103
    • 0030815178 scopus 로고    scopus 로고
    • Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans
    • Gebhardt AC, Lucas D, Menez JF, Seitz HK. Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans. Hepatology 1997; 26: 957-961
    • (1997) Hepatology , vol.26 , pp. 957-961
    • Gebhardt, A.C.1    Lucas, D.2    Menez, J.F.3    Seitz, H.K.4
  • 104
    • 0031900249 scopus 로고    scopus 로고
    • Endotoxemia, pentose cycle, and the oxidant/ antioxidant balance in the hepatic sinusoid
    • Spolarics Z. Endotoxemia, pentose cycle, and the oxidant/ antioxidant balance in the hepatic sinusoid. J Leukoc Biol 1998; 63: 534-541
    • (1998) J Leukoc Biol , vol.63 , pp. 534-541
    • Spolarics, Z.1
  • 107
    • 37349108815 scopus 로고    scopus 로고
    • Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis
    • Jeong WI, Park O, Gao B. Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis. Gastroenterology 2008; 134: 248-258
    • (2008) Gastroenterology , vol.134 , pp. 248-258
    • Jeong, W.I.1    Park, O.2    Gao, B.3
  • 110
    • 2142809627 scopus 로고    scopus 로고
    • The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia
    • Ioannou GN, Dominitz JA, Weiss NS, Heagerty PJ, Kowdley KV. The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia. Gastroenterology 2004; 126: 1293-1301
    • (2004) Gastroenterology , vol.126 , pp. 1293-1301
    • Ioannou, G.N.1    Dominitz, J.A.2    Weiss, N.S.3    Heagerty, P.J.4    Kowdley, K.V.5
  • 112
    • 0031801787 scopus 로고    scopus 로고
    • Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C
    • Smith BC, Gorve J, Guzail MA, Day CP, Daly AK, Burt AD, Bassendine MF. Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C. Hepatology 1998; 27: 1695-1699
    • (1998) Hepatology , vol.27 , pp. 1695-1699
    • Smith, B.C.1    Gorve, J.2    Guzail, M.A.3    Day, C.P.4    Daly, A.K.5    Burt, A.D.6    Bassendine, M.F.7
  • 114
    • 0022368621 scopus 로고
    • Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
    • Niederau C, Fischer R, Sonnenberg A, Stremmel W, Trampisch HJ, Strohmeyer G. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med 1985; 313: 1256-1262
    • (1985) N Engl J Med , vol.313 , pp. 1256-1262
    • Niederau, C.1    Fischer, R.2    Sonnenberg, A.3    Stremmel, W.4    Trampisch, H.J.5    Strohmeyer, G.6
  • 115
    • 0032761853 scopus 로고    scopus 로고
    • Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection
    • Huang H, Fujii H, Sankila A, Mahler-Araujo BM, Matsuda M, Cathomas G, Ohgaki H. Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection. Am J Pathol 1999; 155: 1795-1801
    • (1999) Am J Pathol , vol.155 , pp. 1795-1801
    • Huang, H.1    Fujii, H.2    Sankila, A.3    Mahler-Araujo, B.M.4    Matsuda, M.5    Cathomas, G.6    Ohgaki, H.7
  • 116
    • 0023803172 scopus 로고
    • Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis
    • Green R, Esparza I, Schreiber R. Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis. Ann N Y Acad Sci 1988; 526: 301-309
    • (1988) Ann N Y Acad Sci , vol.526 , pp. 301-309
    • Green, R.1    Esparza, I.2    Schreiber, R.3
  • 121
    • 33846564416 scopus 로고    scopus 로고
    • Liver-homing of purified glucose oxidase: A novel in vivo model of physiological hepatic oxidative stress (H2O2)
    • Rost D, Welker A, Welker J, Millonig G, Berger I, Autschbach F, Schuppan D, Mueller S. Liver-homing of purified glucose oxidase: a novel in vivo model of physiological hepatic oxidative stress (H2O2). J Hepatol 2007; 46: 482-491
    • (2007) J Hepatol , vol.46 , pp. 482-491
    • Rost, D.1    Welker, A.2    Welker, J.3    Millonig, G.4    Berger, I.5    Autschbach, F.6    Schuppan, D.7    Mueller, S.8
  • 122
    • 0034282101 scopus 로고    scopus 로고
    • Sensitive and nonenzymatic measurement of hydrogen peroxide in biological systems
    • Mueller S. Sensitive and nonenzymatic measurement of hydrogen peroxide in biological systems. Free Radic Biol Med 2000; 29: 410-415
    • (2000) Free Radic Biol Med , vol.29 , pp. 410-415
    • Mueller, S.1
  • 123
    • 0035933846 scopus 로고    scopus 로고
    • IRP1 activation by extracellular oxidative stress in the perfused rat liver
    • Mueller S, Pantopoulos K, Hubner CA, Stremmel W, Hentze MW. IRP1 activation by extracellular oxidative stress in the perfused rat liver. J Biol Chem 2001; 276: 23192-23196
    • (2001) J Biol Chem , vol.276 , pp. 23192-23196
    • Mueller, S.1    Pantopoulos, K.2    Hubner, C.A.3    Stremmel, W.4    Hentze, M.W.5
  • 124
    • 34547125378 scopus 로고    scopus 로고
    • Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron-responsive element network
    • Andriopoulos B, Hegedusch S, Mangin J, Riedel HD, Hebling U, Wang J, Pantopoulos K, Mueller S. Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron-responsive element network. J Biol Chem 2007; 282: 20301-20308
    • (2007) J Biol Chem , vol.282 , pp. 20301-20308
    • Andriopoulos, B.1    Hegedusch, S.2    Mangin, J.3    Riedel, H.D.4    Hebling, U.5    Wang, J.6    Pantopoulos, K.7    Mueller, S.8
  • 125
    • 7044272621 scopus 로고    scopus 로고
    • Pathogenesis of hepatitis C-associated hepatocellular carcinoma
    • Liang TJ, Heller T. Pathogenesis of hepatitis C-associated hepatocellular carcinoma. Gastroenterology 2004; 127: S62-S71
    • (2004) Gastroenterology , vol.127
    • Liang, T.J.1    Heller, T.2
  • 131
    • 0027202804 scopus 로고
    • A unique rodent model for both the cardiotoxic and hepatotoxic effects of prolonged iron overload
    • Carthew P, Dorman BM, Edwards RE, Francis JE, Smith AG. A unique rodent model for both the cardiotoxic and hepatotoxic effects of prolonged iron overload. Lab Invest 1993; 69: 217-222
    • (1993) Lab Invest , vol.69 , pp. 217-222
    • Carthew, P.1    Dorman, B.M.2    Edwards, R.E.3    Francis, J.E.4    Smith, A.G.5
  • 133
  • 135
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-1276
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3    Keller, C.4    Taudorf, S.5    Pedersen, B.K.6    Ganz, T.7
  • 136
    • 28644443925 scopus 로고    scopus 로고
    • Iron regulatory protein 1 as a sensor of reactive oxygen species
    • Mueller S. Iron regulatory protein 1 as a sensor of reactive oxygen species. Biofactors 2005; 24: 171-181
    • (2005) Biofactors , vol.24 , pp. 171-181
    • Mueller, S.1
  • 137
    • 3943098598 scopus 로고    scopus 로고
    • Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3
    • Theurl I, Zoller H, Obrist P, Datz C, Bachmann F, Elliott RM, Weiss G. Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3. J Infect Dis 2004; 190: 819-825
    • (2004) J Infect Dis , vol.190 , pp. 819-825
    • Theurl, I.1    Zoller, H.2    Obrist, P.3    Datz, C.4    Bachmann, F.5    Elliott, R.M.6    Weiss, G.7
  • 138
    • 19544363018 scopus 로고    scopus 로고
    • IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities
    • Fillebeen C, Caltagirone A, Martelli A, Moulis JM, Pantopoulos K. IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities. Biochem J 2005; 388: 143-150
    • (2005) Biochem J , vol.388 , pp. 143-150
    • Fillebeen, C.1    Caltagirone, A.2    Martelli, A.3    Moulis, J.M.4    Pantopoulos, K.5
  • 139
    • 0036117799 scopus 로고    scopus 로고
    • Hepatic iron overload does not prevent a sustained virological response to interferon-alpha therapy: A long term follow-up study in hepatitis C-infected patients with beta thalassemia major
    • Sievert W, Pianko S, Warner S, Bowden S, Simpson I, Bowden D, Locarnini S. Hepatic iron overload does not prevent a sustained virological response to interferon-alpha therapy: a long term follow-up study in hepatitis C-infected patients with beta thalassemia major. Am J Gastroenterol 2002; 97: 982-987
    • (2002) Am J Gastroenterol , vol.97 , pp. 982-987
    • Sievert, W.1    Pianko, S.2    Warner, S.3    Bowden, S.4    Simpson, I.5    Bowden, D.6    Locarnini, S.7
  • 141
    • 0031948693 scopus 로고    scopus 로고
    • Independent and combined action of hepatitis C virus infection and alcohol consumption on the risk of symptomatic liver cirrhosis
    • Corrao G, Arico S. Independent and combined action of hepatitis C virus infection and alcohol consumption on the risk of symptomatic liver cirrhosis. Hepatology 1998; 27: 914-919
    • (1998) Hepatology , vol.27 , pp. 914-919
    • Corrao, G.1    Arico, S.2


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