-
1
-
-
0028283579
-
Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product
-
Sudol M. Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product. Oncogene 1994, 9:2145-2152.
-
(1994)
Oncogene
, vol.9
, pp. 2145-2152
-
-
Sudol, M.1
-
2
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
-
Huang J., Wu S., Barrera J., et al. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 2005, 122:421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
-
3
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
Lai Z.C., Wei X., Shimizu T., et al. Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 2005, 120:675-685.
-
(2005)
Cell
, vol.120
, pp. 675-685
-
-
Lai, Z.C.1
Wei, X.2
Shimizu, T.3
-
4
-
-
0042232429
-
Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
Wu S., Huang J., Dong J., et al. Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 2003, 114:445-456.
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
-
5
-
-
34247191134
-
Hippo signaling in organ size control
-
Pan D. Hippo signaling in organ size control. Genes & Development 2007, 21:886-897.
-
(2007)
Genes & Development
, vol.21
, pp. 886-897
-
-
Pan, D.1
-
6
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. The hippo signaling pathway in development and cancer. Developmental Cell 2010, 19:491-505.
-
(2010)
Developmental Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
7
-
-
0032954260
-
Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
-
Tao W., Zhang S., Turenchalk G.S., et al. Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nature Genetics 1999, 21:177-181.
-
(1999)
Nature Genetics
, vol.21
, pp. 177-181
-
-
Tao, W.1
Zhang, S.2
Turenchalk, G.S.3
-
8
-
-
84884291548
-
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
-
Yin F., Yu J., Zheng Y., et al. Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell 2013, 154:1342-1355.
-
(2013)
Cell
, vol.154
, pp. 1342-1355
-
-
Yin, F.1
Yu, J.2
Zheng, Y.3
-
9
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J., Feldmann G., Huang J., et al. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007, 130:1120-1133.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
-
10
-
-
0035873391
-
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
-
Vassilev A., Kaneko K.J., Shu H., et al. TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes & Development 2001, 15:1229-1241.
-
(2001)
Genes & Development
, vol.15
, pp. 1229-1241
-
-
Vassilev, A.1
Kaneko, K.J.2
Shu, H.3
-
11
-
-
84862605178
-
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
-
Liu-Chittenden Y., Huang B., Shim J.S., et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes & Development 2012, 26:1300-1305.
-
(2012)
Genes & Development
, vol.26
, pp. 1300-1305
-
-
Liu-Chittenden, Y.1
Huang, B.2
Shim, J.S.3
-
12
-
-
84878371755
-
The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression
-
Koontz L.M., Liu-Chittenden Y., Yin F., et al. The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression. Developmental Cell 2013, 25:388-401.
-
(2013)
Developmental Cell
, vol.25
, pp. 388-401
-
-
Koontz, L.M.1
Liu-Chittenden, Y.2
Yin, F.3
-
14
-
-
33645224114
-
Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65
-
Morin-Kensicki E.M., Boone B.N., Howell M., et al. Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65. Molecular and Cellular Biology 2006, 26:77-87.
-
(2006)
Molecular and Cellular Biology
, vol.26
, pp. 77-87
-
-
Morin-Kensicki, E.M.1
Boone, B.N.2
Howell, M.3
-
15
-
-
77954945373
-
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
-
Zhang N., Bai H., David K.K., et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Developmental Cell 2010, 19:27-38.
-
(2010)
Developmental Cell
, vol.19
, pp. 27-38
-
-
Zhang, N.1
Bai, H.2
David, K.K.3
-
16
-
-
49649111405
-
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice
-
Geisler F., Nagl F., Mazur P.K., et al. Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology 2008, 48:607-616.
-
(2008)
Hepatology
, vol.48
, pp. 607-616
-
-
Geisler, F.1
Nagl, F.2
Mazur, P.K.3
-
17
-
-
33745856213
-
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
-
Xu X., Kobayashi S., Qiao W., et al. Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. Journal of Clinical Investigation 2006, 116:1843-1852.
-
(2006)
Journal of Clinical Investigation
, vol.116
, pp. 1843-1852
-
-
Xu, X.1
Kobayashi, S.2
Qiao, W.3
-
18
-
-
0037213681
-
Development of the biliary tract
-
Lemaigre F.P. Development of the biliary tract. Mechanisms of Development 2003, 120:81-87.
-
(2003)
Mechanisms of Development
, vol.120
, pp. 81-87
-
-
Lemaigre, F.P.1
-
20
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu F., Willecke M., Kango-Singh M., et al. The tumour-suppressor genes NF2/Merlin and expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nature Cell Biology 2006, 8:27-36.
-
(2006)
Nature Cell Biology
, vol.8
, pp. 27-36
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
-
21
-
-
46149099112
-
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity
-
Yu J., Poulton J., Huang Y.C., et al. The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS ONE 2008, 3:e1761.
-
(2008)
PLoS ONE
, vol.3
, pp. e1761
-
-
Yu, J.1
Poulton, J.2
Huang, Y.C.3
-
22
-
-
80052169853
-
The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis
-
Chen H.J., Wang C.M., Wang T.W., et al. The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis. Developmental Biology 2011, 357:370-379.
-
(2011)
Developmental Biology
, vol.357
, pp. 370-379
-
-
Chen, H.J.1
Wang, C.M.2
Wang, T.W.3
-
23
-
-
84878273791
-
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma
-
e12
-
Tschaharganeh D.F., Chen X., Latzko P., et al. Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma. Gastroenterology 2013, 144:1530-1542. e12.
-
(2013)
Gastroenterology
, vol.144
, pp. 1530-1542
-
-
Tschaharganeh, D.F.1
Chen, X.2
Latzko, P.3
-
24
-
-
84902081616
-
Hippo pathway activity influences liver cell fate
-
Yimlamai D., Christodoulou C., Galli G.G., et al. Hippo pathway activity influences liver cell fate. Cell 2014, 157:1324-1338.
-
(2014)
Cell
, vol.157
, pp. 1324-1338
-
-
Yimlamai, D.1
Christodoulou, C.2
Galli, G.G.3
-
25
-
-
0036339631
-
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
-
McCright B., Lozier J., Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 2002, 129:1075-1082.
-
(2002)
Development
, vol.129
, pp. 1075-1082
-
-
McCright, B.1
Lozier, J.2
Gridley, T.3
-
26
-
-
84865571180
-
Yes-associated protein regulates the hepatic response after bile duct ligation
-
Bai H., Zhang N., Xu Y., et al. Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology 2012, 56:1097-1107.
-
(2012)
Hepatology
, vol.56
, pp. 1097-1107
-
-
Bai, H.1
Zhang, N.2
Xu, Y.3
-
27
-
-
77955868800
-
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver
-
Benhamouche S., Curto M., Saotome I., et al. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes & Development 2010, 24:1718-1730.
-
(2010)
Genes & Development
, vol.24
, pp. 1718-1730
-
-
Benhamouche, S.1
Curto, M.2
Saotome, I.3
-
28
-
-
43549120265
-
Characterization of time-related changes after experimental bile duct ligation
-
Georgiev P., Jochum W., Heinrich S., et al. Characterization of time-related changes after experimental bile duct ligation. British Journal of Surgery 2008, 95:646-656.
-
(2008)
British Journal of Surgery
, vol.95
, pp. 646-656
-
-
Georgiev, P.1
Jochum, W.2
Heinrich, S.3
-
29
-
-
70349232394
-
Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase
-
Apte U., Gkretsi V., Bowen W.C., et al. Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase. Hepatology 2009, 50:844-851.
-
(2009)
Hepatology
, vol.50
, pp. 844-851
-
-
Apte, U.1
Gkretsi, V.2
Bowen, W.C.3
-
30
-
-
84862907748
-
Differences in Yes-associated protein and mRNA levels in regenerating liver and hepatocellular carcinoma
-
Wang C., Zhang L., He Q., et al. Differences in Yes-associated protein and mRNA levels in regenerating liver and hepatocellular carcinoma. Molecular Medicine Reports 2012, 5:410-414.
-
(2012)
Molecular Medicine Reports
, vol.5
, pp. 410-414
-
-
Wang, C.1
Zhang, L.2
He, Q.3
-
31
-
-
84878619758
-
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense
-
Wu H., Xiao Y., Zhang S., et al. The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense. Cell Reports 2013, 3:1663-1677.
-
(2013)
Cell Reports
, vol.3
, pp. 1663-1677
-
-
Wu, H.1
Xiao, Y.2
Zhang, S.3
-
32
-
-
14244252656
-
Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury
-
Michalopoulos G.K., Barua L., Bowen W.C. Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury. Hepatology 2005, 41:535-544.
-
(2005)
Hepatology
, vol.41
, pp. 535-544
-
-
Michalopoulos, G.K.1
Barua, L.2
Bowen, W.C.3
-
33
-
-
80053610625
-
The ductal plate: a source of progenitors and hepatocytes in the adult liver
-
Greenbaum L.E. The ductal plate: a source of progenitors and hepatocytes in the adult liver. Gastroenterology 2011, 141:1152-1155.
-
(2011)
Gastroenterology
, vol.141
, pp. 1152-1155
-
-
Greenbaum, L.E.1
-
34
-
-
84925103805
-
YAP inhibition restores hepatocyte differentiation in advanced HCC, leading to tumor regression
-
Fitamant J., Kottakis F., Benhamouche S., et al. YAP inhibition restores hepatocyte differentiation in advanced HCC, leading to tumor regression. Cell Reports 2015, 10:1692-1707.
-
(2015)
Cell Reports
, vol.10
, pp. 1692-1707
-
-
Fitamant, J.1
Kottakis, F.2
Benhamouche, S.3
-
35
-
-
78049451932
-
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
-
Cai J., Zhang N., Zheng Y., et al. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes & Development 2010, 24:2383-2388.
-
(2010)
Genes & Development
, vol.24
, pp. 2383-2388
-
-
Cai, J.1
Zhang, N.2
Zheng, Y.3
-
36
-
-
84871789026
-
Restriction of intestinal stem cell expansion and the regenerative response by YAP
-
Barry E.R., Morikawa T., Butler B.L., et al. Restriction of intestinal stem cell expansion and the regenerative response by YAP. Nature 2013, 493:106-110.
-
(2013)
Nature
, vol.493
, pp. 106-110
-
-
Barry, E.R.1
Morikawa, T.2
Butler, B.L.3
-
37
-
-
84871862870
-
Hippo signaling regulates pancreas development through inactivation of Yap
-
George N.M., Day C.E., Boerner B.P., et al. Hippo signaling regulates pancreas development through inactivation of Yap. Molecular and Cellular Biology 2012, 32:5116-5128.
-
(2012)
Molecular and Cellular Biology
, vol.32
, pp. 5116-5128
-
-
George, N.M.1
Day, C.E.2
Boerner, B.P.3
-
38
-
-
84878282156
-
Hippo signaling regulates differentiation and maintenance in the exocrine pancreas
-
e1
-
Gao T., Zhou D., Yang C., et al. Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology 2013, 144:1543-1553. e1.
-
(2013)
Gastroenterology
, vol.144
, pp. 1543-1553
-
-
Gao, T.1
Zhou, D.2
Yang, C.3
-
39
-
-
84922826380
-
Hippo pathway regulation of gastrointestinal tissues
-
Yu F.X., Meng Z., Plouffe S.W., et al. Hippo pathway regulation of gastrointestinal tissues. Annual Review of Physiology 2015, 77:201-227.
-
(2015)
Annual Review of Physiology
, vol.77
, pp. 201-227
-
-
Yu, F.X.1
Meng, Z.2
Plouffe, S.W.3
-
40
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
Zender L., Spector M.S., Xue W., et al. Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 2006, 125:1253-1267.
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
-
41
-
-
0035884398
-
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas
-
Imoto I., Yang Z.Q., Pimkhaokham A., et al. Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Research 2001, 61:6629-6634.
-
(2001)
Cancer Research
, vol.61
, pp. 6629-6634
-
-
Imoto, I.1
Yang, Z.Q.2
Pimkhaokham, A.3
-
42
-
-
0037388691
-
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes
-
Dai Z., Zhu W.G., Morrison C.D., et al. A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes. Human Molecular Genetics 2003, 12:791-801.
-
(2003)
Human Molecular Genetics
, vol.12
, pp. 791-801
-
-
Dai, Z.1
Zhu, W.G.2
Morrison, C.D.3
-
43
-
-
22044450542
-
Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
-
Bashyam M.D., Bair R., Kim Y.H., et al. Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer. Neoplasia 2005, 7:556-562.
-
(2005)
Neoplasia
, vol.7
, pp. 556-562
-
-
Bashyam, M.D.1
Bair, R.2
Kim, Y.H.3
-
44
-
-
20544465379
-
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
-
Snijders A.M., Schmidt B.L., Fridlyand J., et al. Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene 2005, 24:4232-4242.
-
(2005)
Oncogene
, vol.24
, pp. 4232-4242
-
-
Snijders, A.M.1
Schmidt, B.L.2
Fridlyand, J.3
-
46
-
-
0035341895
-
The Ste20 group kinases as regulators of MAP kinase cascades
-
Dan I., Watanabe N.M., Kusumi A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends in Cell Biology 2001, 11:220-230.
-
(2001)
Trends in Cell Biology
, vol.11
, pp. 220-230
-
-
Dan, I.1
Watanabe, N.M.2
Kusumi, A.3
-
47
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
Zhou D., Conrad C., Xia F., et al. Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 2009, 16:425-438.
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
-
49
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
Lee K.P., Lee J.H., Kim T.S., et al. The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:8248-8253.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
-
51
-
-
84906934146
-
Activation of beta-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice
-
Tao J., Calvisi D.F., Ranganathan S., et al. Activation of beta-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice. Gastroenterology 2014, 147:690-701.
-
(2014)
Gastroenterology
, vol.147
, pp. 690-701
-
-
Tao, J.1
Calvisi, D.F.2
Ranganathan, S.3
-
52
-
-
79957465561
-
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice
-
Kowalik M.A., Saliba C., Pibiri M., et al. Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice. Hepatology 2011, 53:2086-2096.
-
(2011)
Hepatology
, vol.53
, pp. 2086-2096
-
-
Kowalik, M.A.1
Saliba, C.2
Pibiri, M.3
-
53
-
-
84930204654
-
YAP activation is an early event and a potential therapeutic target in liver cancer development
-
Perra A., Kowalik M.A., Ghiso E., et al. YAP activation is an early event and a potential therapeutic target in liver cancer development. Journal of Hepatology 2014, 61:1088-1096.
-
(2014)
Journal of Hepatology
, vol.61
, pp. 1088-1096
-
-
Perra, A.1
Kowalik, M.A.2
Ghiso, E.3
-
54
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao B., Wei X., Li W., et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes & Development 2007, 21:2747-2761.
-
(2007)
Genes & Development
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
-
55
-
-
70349295967
-
Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
-
Xu M.Z., Yao T.J., Lee N.P., et al. Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma. Cancer 2009, 115:4576-4585.
-
(2009)
Cancer
, vol.115
, pp. 4576-4585
-
-
Xu, M.Z.1
Yao, T.J.2
Lee, N.P.3
-
56
-
-
84864281802
-
Expression of Yes-associated protein modulates survivin expression in primary liver malignancies
-
Bai H., Gayyed M.F., Lam-Himlin D.M., et al. Expression of Yes-associated protein modulates survivin expression in primary liver malignancies. Human Pathology 2012, 43:1376-1385.
-
(2012)
Human Pathology
, vol.43
, pp. 1376-1385
-
-
Bai, H.1
Gayyed, M.F.2
Lam-Himlin, D.M.3
-
58
-
-
84870531955
-
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells
-
Zhang T., Zhang J., You X., et al. Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells. Hepatology 2012, 56:2051-2059.
-
(2012)
Hepatology
, vol.56
, pp. 2051-2059
-
-
Zhang, T.1
Zhang, J.2
You, X.3
-
59
-
-
84880538284
-
RASSF1A-mediated regulation of AREG via the Hippo pathway in hepatocellular carcinoma
-
Ahn E.Y., Kim J.S., Kim G.J., et al. RASSF1A-mediated regulation of AREG via the Hippo pathway in hepatocellular carcinoma. Molecular Cancer Research: MCR 2013, 11:748-758.
-
(2013)
Molecular Cancer Research: MCR
, vol.11
, pp. 748-758
-
-
Ahn, E.Y.1
Kim, J.S.2
Kim, G.J.3
-
60
-
-
84879139034
-
Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53
-
Bai N., Zhang C., Liang N., et al. Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biology & Therapy 2013, 14:511-520.
-
(2013)
Cancer Biology & Therapy
, vol.14
, pp. 511-520
-
-
Bai, N.1
Zhang, C.2
Liang, N.3
-
61
-
-
79952532529
-
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
-
Xu M.Z., Chan S.W., Liu A.M., et al. AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. Oncogene 2011, 30:1229-1240.
-
(2011)
Oncogene
, vol.30
, pp. 1229-1240
-
-
Xu, M.Z.1
Chan, S.W.2
Liu, A.M.3
-
62
-
-
84898801231
-
The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease
-
Gurda G.T., Zhu Q., Bai H., et al. The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease. Human Pathology 2014, 45:1057-1064.
-
(2014)
Human Pathology
, vol.45
, pp. 1057-1064
-
-
Gurda, G.T.1
Zhu, Q.2
Bai, H.3
-
63
-
-
84888430367
-
Bile acids activate YAP to promote liver carcinogenesis
-
Anakk S., Bhosale M., Schmidt V.A., et al. Bile acids activate YAP to promote liver carcinogenesis. Cell Reports 2013, 5:1060-1069.
-
(2013)
Cell Reports
, vol.5
, pp. 1060-1069
-
-
Anakk, S.1
Bhosale, M.2
Schmidt, V.A.3
-
64
-
-
84879660191
-
Reciprocal regulation by TLR4 and TGF-beta in tumor-initiating stem-like cells
-
Chen C.L., Tsukamoto H., Liu J.C., et al. Reciprocal regulation by TLR4 and TGF-beta in tumor-initiating stem-like cells. Journal of Clinical Investigation 2013, 123:2832-2849.
-
(2013)
Journal of Clinical Investigation
, vol.123
, pp. 2832-2849
-
-
Chen, C.L.1
Tsukamoto, H.2
Liu, J.C.3
-
65
-
-
84883235155
-
Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer
-
Wang J., Ma L., Weng W., et al. Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer. Hepatology 2013, 58:1011-1020.
-
(2013)
Hepatology
, vol.58
, pp. 1011-1020
-
-
Wang, J.1
Ma, L.2
Weng, W.3
-
66
-
-
82455210238
-
Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation
-
Urtasun R., Latasa M.U., Demartis M.I., et al. Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation. Hepatology 2011, 54:2149-2158.
-
(2011)
Hepatology
, vol.54
, pp. 2149-2158
-
-
Urtasun, R.1
Latasa, M.U.2
Demartis, M.I.3
-
67
-
-
10744224167
-
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
-
Hughes C.M., Rozenblatt-Rosen O., Milne T.A., et al. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Molecular Cell 2004, 13:587-597.
-
(2004)
Molecular Cell
, vol.13
, pp. 587-597
-
-
Hughes, C.M.1
Rozenblatt-Rosen, O.2
Milne, T.A.3
-
69
-
-
77950626836
-
MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties
-
Liu A.M., Poon R.T., Luk J.M. MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. Biochemical and Biophysical Research Communications 2010, 394:623-627.
-
(2010)
Biochemical and Biophysical Research Communications
, vol.394
, pp. 623-627
-
-
Liu, A.M.1
Poon, R.T.2
Luk, J.M.3
-
70
-
-
0032493903
-
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion
-
Kuroda S., Fukata M., Nakagawa M., et al. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion. Science 1998, 281:832-835.
-
(1998)
Science
, vol.281
, pp. 832-835
-
-
Kuroda, S.1
Fukata, M.2
Nakagawa, M.3
-
72
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S., Morsut L., Aragona M., et al. Role of YAP/TAZ in mechanotransduction. Nature 2011, 474:179-183.
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
-
73
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
Calvo F., Ege N., Grande-Garcia A., et al. Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nature Cell Biology 2013, 15:637-646.
-
(2013)
Nature Cell Biology
, vol.15
, pp. 637-646
-
-
Calvo, F.1
Ege, N.2
Grande-Garcia, A.3
-
74
-
-
84855326431
-
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
-
Zhao B., Li L., Wang L., et al. Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes & Development 2012, 26:54-68.
-
(2012)
Genes & Development
, vol.26
, pp. 54-68
-
-
Zhao, B.1
Li, L.2
Wang, L.3
-
75
-
-
84883466306
-
A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
-
Aragona M., Panciera T., Manfrin A., et al. A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell 2013, 154:1047-1059.
-
(2013)
Cell
, vol.154
, pp. 1047-1059
-
-
Aragona, M.1
Panciera, T.2
Manfrin, A.3
-
76
-
-
84926258240
-
The spectrin cytoskeleton regulates the Hippo signalling pathway
-
Fletcher G.C., Elbediwy A., Khanal I., et al. The spectrin cytoskeleton regulates the Hippo signalling pathway. The EMBO Journal 2015, 34:940-954.
-
(2015)
The EMBO Journal
, vol.34
, pp. 940-954
-
-
Fletcher, G.C.1
Elbediwy, A.2
Khanal, I.3
-
77
-
-
84926338403
-
Spectrin regulates Hippo signaling by modulating cortical actomyosin activity
-
Deng H., Wang W., Yu J., et al. Spectrin regulates Hippo signaling by modulating cortical actomyosin activity. Elife 2015, 4:e06567.
-
(2015)
Elife
, vol.4
, pp. e06567
-
-
Deng, H.1
Wang, W.2
Yu, J.3
-
78
-
-
84919595168
-
Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein
-
DeRan M., Yang J., Shen C.H., et al. Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein. Cell Reports 2014, 9:495-503.
-
(2014)
Cell Reports
, vol.9
, pp. 495-503
-
-
DeRan, M.1
Yang, J.2
Shen, C.H.3
-
79
-
-
84925970129
-
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
-
Mo J.S., Meng Z., Kim Y.C., et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nature Cell Biology 2015, 17:500-510.
-
(2015)
Nature Cell Biology
, vol.17
, pp. 500-510
-
-
Mo, J.S.1
Meng, Z.2
Kim, Y.C.3
-
80
-
-
84874257648
-
The Hippo pathway: regulators and regulations
-
Yu F.X., Guan K.L. The Hippo pathway: regulators and regulations. Genes & Development 2013, 27:355-371.
-
(2013)
Genes & Development
, vol.27
, pp. 355-371
-
-
Yu, F.X.1
Guan, K.L.2
-
81
-
-
84921438953
-
Impaired trace fear conditioning and diminished ERK1/2 phosphorylation in the dorsal hippocampus of adult rats administered alcohol as neonates
-
DuPont C.M., Coppola J.J., Kaercher R.M., et al. Impaired trace fear conditioning and diminished ERK1/2 phosphorylation in the dorsal hippocampus of adult rats administered alcohol as neonates. Behavioral Neuroscience 2014, 128:187-198.
-
(2014)
Behavioral Neuroscience
, vol.128
, pp. 187-198
-
-
DuPont, C.M.1
Coppola, J.J.2
Kaercher, R.M.3
-
82
-
-
84865455267
-
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP
-
Miller E., Yang J., DeRan M., et al. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chemistry & Biology 2012, 19:955-962.
-
(2012)
Chemistry & Biology
, vol.19
, pp. 955-962
-
-
Miller, E.1
Yang, J.2
DeRan, M.3
-
83
-
-
84865260845
-
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
-
Yu F.X., Zhao B., Panupinthu N., et al. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 2012, 150:780-791.
-
(2012)
Cell
, vol.150
, pp. 780-791
-
-
Yu, F.X.1
Zhao, B.2
Panupinthu, N.3
-
84
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
-
Zhao B., Li L., Tumaneng K., et al. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes & Development 2010, 24:72-85.
-
(2010)
Genes & Development
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
-
85
-
-
0035805487
-
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
-
Strano S., Munarriz E., Rossi M., et al. Physical interaction with Yes-associated protein enhances p73 transcriptional activity. Journal of Biological Chemistry 2001, 276:15164-15173.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 15164-15173
-
-
Strano, S.1
Munarriz, E.2
Rossi, M.3
-
86
-
-
0033522472
-
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
-
Yagi R., Chen L.F., Shigesada K., et al. A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. The EMBO Journal 1999, 18:2551-2562.
-
(1999)
The EMBO Journal
, vol.18
, pp. 2551-2562
-
-
Yagi, R.1
Chen, L.F.2
Shigesada, K.3
-
87
-
-
60849138138
-
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
-
Ota M., Sasaki H. Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development 2008, 135:4059-4069.
-
(2008)
Development
, vol.135
, pp. 4059-4069
-
-
Ota, M.1
Sasaki, H.2
-
88
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
Zhao B., Ye X., Yu J., et al. TEAD mediates YAP-dependent gene induction and growth control. Genes & Development 2008, 22:1962-1971.
-
(2008)
Genes & Development
, vol.22
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
-
89
-
-
43249089639
-
Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival
-
Sawada A., Kiyonari H., Ukita K., et al. Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival. Molecular and Cellular Biology 2008, 28:3177-3189.
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 3177-3189
-
-
Sawada, A.1
Kiyonari, H.2
Ukita, K.3
-
90
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
Zhang J., Ji J.Y., Yu M., et al. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nature Cell Biology 2009, 11:1444-1450.
-
(2009)
Nature Cell Biology
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
Ji, J.Y.2
Yu, M.3
-
91
-
-
84893710162
-
The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity
-
Shimomura T., Miyamura N., Hata S., et al. The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity. Biochemical and Biophysical Research Communications 2014, 443:917-923.
-
(2014)
Biochemical and Biophysical Research Communications
, vol.443
, pp. 917-923
-
-
Shimomura, T.1
Miyamura, N.2
Hata, S.3
-
92
-
-
84884279358
-
Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancer
-
Xiao W., Wang J., Ou C., et al. Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancer. Biochemical and Biophysical Research Communications 2013, 439:167-172.
-
(2013)
Biochemical and Biophysical Research Communications
, vol.439
, pp. 167-172
-
-
Xiao, W.1
Wang, J.2
Ou, C.3
-
93
-
-
84885186496
-
A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity
-
Guo T., Lu Y., Li P., et al. A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity. Cell Research 2013, 23:1201-1214.
-
(2013)
Cell Research
, vol.23
, pp. 1201-1214
-
-
Guo, T.1
Lu, Y.2
Li, P.3
-
94
-
-
84893576085
-
A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer
-
Jiao S., Wang H., Shi Z., et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell 2014, 25:166-180.
-
(2014)
Cancer Cell
, vol.25
, pp. 166-180
-
-
Jiao, S.1
Wang, H.2
Shi, Z.3
-
95
-
-
84890916735
-
Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
-
Serrano I., McDonald P.C., Lock F., et al. Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nature Communications 2013, 4:2976.
-
(2013)
Nature Communications
, vol.4
, pp. 2976
-
-
Serrano, I.1
McDonald, P.C.2
Lock, F.3
-
96
-
-
80051923057
-
Hippo pathway regulation by cell morphology and stress fibers
-
Wada K., Itoga K., Okano T., et al. Hippo pathway regulation by cell morphology and stress fibers. Development 2011, 138:3907-3914.
-
(2011)
Development
, vol.138
, pp. 3907-3914
-
-
Wada, K.1
Itoga, K.2
Okano, T.3
-
97
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo F.D., Gokhale S., Johnnidis J.B., et al. YAP1 increases organ size and expands undifferentiated progenitor cells. Current Biology: CB 2007, 17:2054-2060.
-
(2007)
Current Biology: CB
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
-
98
-
-
48349125616
-
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
-
Saburi S., Hester I., Fischer E., et al. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nature Genetics 2008, 40:1010-1015.
-
(2008)
Nature Genetics
, vol.40
, pp. 1010-1015
-
-
Saburi, S.1
Hester, I.2
Fischer, E.3
-
99
-
-
84895929894
-
An evolutionary shift in the regulation of the Hippo pathway between mice and flies
-
Bossuyt W., Chen C.L., Chen Q., et al. An evolutionary shift in the regulation of the Hippo pathway between mice and flies. Oncogene 2014, 33:1218-1228.
-
(2014)
Oncogene
, vol.33
, pp. 1218-1228
-
-
Bossuyt, W.1
Chen, C.L.2
Chen, Q.3
-
100
-
-
19944429131
-
Tumor susceptibility of Rassf1a knockout mice
-
Tommasi S., Dammann R., Zhang Z., et al. Tumor susceptibility of Rassf1a knockout mice. Cancer Research 2005, 65:92-98.
-
(2005)
Cancer Research
, vol.65
, pp. 92-98
-
-
Tommasi, S.1
Dammann, R.2
Zhang, Z.3
-
101
-
-
24344435500
-
The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis
-
van der Weyden L., Tachibana K.K., Gonzalez M.A., et al. The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. Molecular and Cellular Biology 2005, 25:8356-8367.
-
(2005)
Molecular and Cellular Biology
, vol.25
, pp. 8356-8367
-
-
van der Weyden, L.1
Tachibana, K.K.2
Gonzalez, M.A.3
-
102
-
-
78049359250
-
Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis
-
Park J., Kang S.I., Lee S.Y., et al. Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis. Journal of Biological Chemistry 2010, 285:35029-35038.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 35029-35038
-
-
Park, J.1
Kang, S.I.2
Lee, S.Y.3
-
103
-
-
0030924657
-
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation
-
McClatchey A.I., Saotome I., Ramesh V., et al. The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes & Development 1997, 11:1253-1265.
-
(1997)
Genes & Development
, vol.11
, pp. 1253-1265
-
-
McClatchey, A.I.1
Saotome, I.2
Ramesh, V.3
-
104
-
-
0032522603
-
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
-
McClatchey A.I., Saotome I., Mercer K., et al. Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. Genes & Development 1998, 12:1121-1133.
-
(1998)
Genes & Development
, vol.12
, pp. 1121-1133
-
-
McClatchey, A.I.1
Saotome, I.2
Mercer, K.3
-
105
-
-
71949114463
-
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse
-
Oh S., Lee D., Kim T., et al. Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Molecular and Cellular Biology 2009, 29:6309-6320.
-
(2009)
Molecular and Cellular Biology
, vol.29
, pp. 6309-6320
-
-
Oh, S.1
Lee, D.2
Kim, T.3
-
106
-
-
42449101282
-
A crucial role of WW45 in developing epithelial tissues in the mouse
-
Lee J.H., Kim T.S., Yang T.H., et al. A crucial role of WW45 in developing epithelial tissues in the mouse. The EMBO Journal 2008, 27:1231-1242.
-
(2008)
The EMBO Journal
, vol.27
, pp. 1231-1242
-
-
Lee, J.H.1
Kim, T.S.2
Yang, T.H.3
-
107
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
St John M.A., Tao W., Fei X., et al. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nature Genetics 1999, 21:182-186.
-
(1999)
Nature Genetics
, vol.21
, pp. 182-186
-
-
St John, M.A.1
Tao, W.2
Fei, X.3
-
108
-
-
20844449390
-
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity
-
McPherson J.P., Tamblyn L., Elia A., et al. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. The EMBO Journal 2004, 23:3677-3688.
-
(2004)
The EMBO Journal
, vol.23
, pp. 3677-3688
-
-
McPherson, J.P.1
Tamblyn, L.2
Elia, A.3
-
109
-
-
84870572443
-
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
-
Nishio M., Hamada K., Kawahara K., et al. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. Journal of Clinical Investigation 2012, 122:4505-4518.
-
(2012)
Journal of Clinical Investigation
, vol.122
, pp. 4505-4518
-
-
Nishio, M.1
Hamada, K.2
Kawahara, K.3
-
111
-
-
84884263282
-
The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis
-
Yi C., Shen Z., Stemmer-Rachamimov A., et al. The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Science Signaling 2013, 6:ra77.
-
(2013)
Science Signaling
, vol.6
, pp. ra77
-
-
Yi, C.1
Shen, Z.2
Stemmer-Rachamimov, A.3
|