Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

Nature Genetics

Volumn 40, Issue 8, 2008, Pages 1010-1015

  Saburi, Sakura ^a   Hester, Ian ^a   Fischer, Evelyne ^b   Pontoglio, Marco ^b   Eremina, Vera ^a   Gessler, Manfred ^c   Quaggin, Sue E ^a,d   Harrison, Robert ^e   Mount, Richard ^e   McNeill, Helen ^a,f  

^a MOUNT SINAI HOSPITAL   (Canada)

^b CNRS   (France)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; NERVE PROTEIN; PROTEIN FAT4; PROTEIN FJX1; PROTEIN VANGL2;

ANIMAL TISSUE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE DISRUPTION; GENE EXPRESSION; GENE INTERACTION; GENE REPRESSION; HISTOPATHOLOGY; KIDNEY POLYCYSTIC DISEASE; MALE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; CADHERINS; CELL DIVISION; CELL POLARITY; DROSOPHILA MELANOGASTER; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; KIDNEY; KIDNEY DISEASES, CYSTIC;

MAMMALIA; VERTEBRATA;

EID: 48349125616     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.179     Document Type: Article

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