The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease

Human Pathology

Volumn 45, Issue 5, 2014, Pages 1057-1064

  Gurda, Grzegorz T ^a   Zhu, Qingfeng ^a   Bai, Haibo ^a   Pan, Duojia ^b   Schwarz, Kathleen B ^b   Anders, Robert A ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bile duct obstruction; Bile ductular reaction; Biliary atresia; Hippo pathway; Neonatal cholestasis; Neurofibromatosis 2 (NF2); Verteporfin (VP); Yes associated protein (YAP)

Indexed keywords

BILE DUCT OBSTRUCTION; BILE DUCTULAR REACTION; BILIARY ATRESIA; HIPPO PATHWAY; NEONATAL CHOLESTASIS; NEUROFIBROMATOSIS 2 (NF2); VERTEPORFIN (VP); YES-ASSOCIATED PROTEIN (YAP);

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; BILE DUCTS; BILIARY ATRESIA; CELL LINE; CHOLESTASIS; FEMALE; HUMANS; INFANT, NEWBORN; JAUNDICE, NEONATAL; LIVER; MALE; MIDDLE AGED; PHOSPHOPROTEINS;

EID: 84898801231     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.01.002     Document Type: Article

References (35)

1. G. Cleghorn Biliary atresia and its micromanagement: does it really matter? J Pediatr 147 2005 142 143
2. A.S. Chu, P.A. Russo, and R.G. Wells Cholangiocyte cilia are abnormal in syndromic and non-syndromic biliary atresia Mod Pathol 25 2012 751 757
3. K.B. Schwarz, B.H. Haber, and R. Philip et al. Extra-hepatic anomalies in infants with biliary atresia: results of a large prospective North American multi-center study Hepatology 58 5 2013 1724 1731
4. J.R. Ehrenkranz, N.G. Lewis, C.R. Kahn, and J. Roth Phlorizin: a review Diabetes Metab Res Rev 21 2005 31 38
5. R.J. Sokol, C. Mack, M.R. Narkewicz, and F.M. Karrer Pathogenesis and outcome of biliary atresia: current concepts J Pediatr Gastroenterol Nutr 37 2003 4 21
6. B.L. Shneider, M.B. Brown, and B. Haber et al. A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000 J Pediatr 148 2006 467 474
7. B.A. Haber, and P. Russo Biliary atresia Gastroenterol Clin North Am 32 2003 891 911
8. P. Russo, J.C. Magee, and J. Boitnott et al. Design and validation of the biliary atresia research consortium histologic assessment system for cholestasis in infancy Clin Gastroenterol Hepatol 2011 357 362 e352
9. M. Torbenson, J. Wang, S. Abraham, A. Maitra, and J. Boitnott Bile ducts and ductules are positive for CD56 (N-CAM) in most cases of extrahepatic biliary atresia Am J Surg Pathol 27 2003 1454 1457
10. D.C. Yamaguti, and F.R. Patricio Morphometrical and immunohistochemical study of intrahepatic bile ducts in biliary atresia Eur J Gastroenterol Hepatol 23 2011 759 765
11. M. Davenport, C. Gonde, and R. Redkar et al. Immunohistochemistry of the liver and biliary tree in extrahepatic biliary atresia J Pediatr Surg 36 2001 1017 1025
12. E.M. Ghoneim, M.M. Sira, A.M. Abd Elaziz, F.O. Khalil, M.M. Sultan, and A.B. Mahmoud Diagnostic value of hepatic intercellular adhesion molecule-1 expression in Egyptian infants with biliary atresia and other forms of neonatal cholestasis Hepatol Res 41 2011 763 775
13. F.E. Mahjoub, R.H. Khairkhah, M.N. Sani, G. Irvanloo, and M. Monajemzadeh CD 56 staining in liver biopsies does not help in differentiating extrahepatic biliary atresia from other causes of neonatal cholestasis Diagn Pathol 3 2008 10
14. U. Broome, A. Nemeth, R. Hultcrantz, and A. Scheynius Different expression of HLA-DR and ICAM-1 in livers from patients with biliary atresia and Byler's disease J Hepatol 26 1997 857 862
15. Y. Liu-Chittenden, B. Huang, and J.S. Shim et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP Genes Dev 26 2012 1300 1305
16. A.A. Steinhardt, M.F. Gayyed, and A.P. Klein et al. Expression of Yes-associated protein in common solid tumors Hum Pathol 39 2008 1582 1589
17. N. Zhang, H. Bai, and K.K. David et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals Dev Cell 19 2010 27 38
18. A.M. Liu, M.Z. Xu, J. Chen, R.T. Poon, and J.M. Luk Targeting YAP and Hippo signaling pathway in liver cancer Expert Opin Ther Targets 14 2010 855 868
19. J. Cai, N. Zhang, Y. Zheng, R.F. de Wilde, A. Maitra, and D. Pan The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program Genes Dev 24 2010 2383 2388
20. S. Septer, G. Edwards, and S. Gunewardena et al. Yes-associated protein is involved in proliferation and differentiation during postnatal liver development Am J Physiol Gastrointest Liver Physiol 2011
21. P.J. Scheuer, R.A. Standish, and A.P. Dhillon Scoring of chronic hepatitis Clin Liver Dis 6 2002 335 347
22. A.K. Bandyopadhyay, T. Das, G. Sa, and M. Mukherjea Effect of fatty acid binding proteins on developing human placental malate dehydrogenase activity Indian J Exp Biol 32 1994 800 803
23. H. Bai, N. Zhang, and Y. Xu et al. Yes-associated protein regulates the hepatic response after bile duct ligation Hepatology 56 2012 1097 1107
24. J. Dong, G. Feldmann, and J. Huang et al. Elucidation of a universal size-control mechanism in Drosophila and mammals Cell 130 2007 1120 1133
25. E. Kahn Biliary atresia revisited Pediatr Dev Pathol 7 2004 109 124
26. V. Moyer, D.K. Freese, and P.F. Whitington et al. Guideline for the evaluation of cholestatic jaundice in infants: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition J Pediatr Gastroenterol Nutr 39 2004 115 128
27. G. Azar, D. Beneck, B. Lane, J. Markowitz, F. Daum, and E. Kahn Atypical morphologic presentation of biliary atresia and value of serial liver biopsies J Pediatr Gastroenterol Nutr 34 2002 212 215
28. M.C. Zerbini, S.D. Gallucci, and R. Maezono et al. Liver biopsy in neonatal cholestasis: a review on statistical grounds Mod Pathol 10 1997 793 799
29. R.K. Moreira, R. Cabral, R.A. Cowles, and S.J. Lobritto Biliary atresia: a multidisciplinary approach to diagnosis and management Arch Pathol Lab Med 136 2012 746 760
30. A.G. Manolaki, V.F. Larcher, A.P. Mowat, J.J. Barrett, B. Portmann, and E.R. Howard The prelaparotomy diagnosis of extrahepatic biliary atresia Arch Dis Child 58 1983 591 594
31. F.D. Camargo, S. Gokhale, and J.B. Johnnidis et al. YAP1 increases organ size and expands undifferentiated progenitor cells Curr Biol 17 2007 2054 2060
32. L.M. Ernst, N.B. Spinner, D.A. Piccoli, J. Mauger, and P. Russo Interlobular bile duct loss in pediatric cholestatic disease is associated with aberrant cytokeratin 7 expression by hepatocytes Pediatr Dev Pathol 10 2007 383 390
33. Y. Low, V. Vijayan, and C.E. Tan The prognostic value of ductal plate malformation and other histologic parameters in biliary atresia: an immunohistochemical study J Pediatr 139 2001 320 322
34. S. Benhamouche, M. Curto, and I. Saotome et al. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver Genes Dev 24 2010 1718 1730
35. P. Mehlen Dependence receptors: the trophic theory revisited Sci Signal 3 2010 e47