Energy stress regulates Hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein

Cell Reports

Volumn 9, Issue 2, 2014, Pages 495-503

  deRan, Michael ^a   Yang, Jiayi ^b   Shen, Che Hung ^a   Peters, Eric C ^b   Fitamant, Julien ^c   Chan, Puiyee ^a   Hsieh, Mindy ^b   Zhu, Shunying ^a   Asara, John M ^c   Zheng, Bin ^a   Bardeesy, Nabeel ^c   Liu, Jun ^b   Wu, Xu ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ANGIOMOTIN LIKE 1 PROTEIN; ANGIOMOTIN LIKE 2 PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LATS1 KINASE; LATS2 KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; TIGHT JUNCTION PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YAP; UNCLASSIFIED DRUG; ADENYLATE KINASE; AMOTL1 PROTEIN, HUMAN; HIPPO PROTEIN, HUMAN; LATS1 PROTEIN, HUMAN; LATS2 PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER CELL LINE; CARCINOGENESIS; CELL ENERGY; CELL METABOLISM; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EMBRYO; ENERGY STRESS; ENZYME ACTIVITY; GENETIC TRANSFECTION; GLUCOSE METABOLISM; HALF LIFE TIME; HEK293 CELL LINE; HIPPO YAP SIGNALING; HUMAN; HUMAN CELL; METABOLIC INHIBITION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RAT; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STEADY STATE; AMINO ACID SEQUENCE; ENERGY METABOLISM; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PHOSPHORYLATION; PHYSIOLOGICAL STRESS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENYLATE KINASE; AMINO ACID SEQUENCE; ENERGY METABOLISM; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84919595168     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.09.036     Document Type: Article

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