-
1
-
-
39849097306
-
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
-
Q. Zeng, W. Hong The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals Cancer Cell 13 2008 188 192
-
(2008)
Cancer Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
2
-
-
79960997489
-
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
-
B. Zhao, K. Tumaneng, K.L. Guan The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal Nat Cell Biol 13 2011 877 883
-
(2011)
Nat Cell Biol
, vol.13
, pp. 877-883
-
-
Zhao, B.1
Tumaneng, K.2
Guan, K.L.3
-
3
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
B. Zhao, X. Wei, W. Li Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control Genes Dev 21 2007 2747 2761
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
-
4
-
-
53849087493
-
Expression of Yes-associated protein in common solid tumors
-
A.A. Steinhardt, M.F. Gayyed, A.P. Klein Expression of Yes-associated protein in common solid tumors Hum Pathol 39 2008 1582 1589
-
(2008)
Hum Pathol
, vol.39
, pp. 1582-1589
-
-
Steinhardt, A.A.1
Gayyed, M.F.2
Klein, A.P.3
-
5
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
J. Dong, G. Feldmann, J. Huang Elucidation of a universal size-control mechanism in Drosophila and mammals Cell 130 2007 1120 1133
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
-
6
-
-
70349295967
-
Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
-
M.Z. Xu, T.J. Yao, N.P. Lee Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma Cancer 115 2009 4576 4585
-
(2009)
Cancer
, vol.115
, pp. 4576-4585
-
-
Xu, M.Z.1
Yao, T.J.2
Lee, N.P.3
-
7
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
L. Zender, M.S. Spector, W. Xue Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach Cell 125 2006 1253 1267
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
-
8
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
F.D. Camargo, S. Gokhale, J.B. Johnnidis YAP1 increases organ size and expands undifferentiated progenitor cells Curr Biol 17 2007 2054 2060
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
-
9
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
K.P. Lee, J.H. Lee, T.S. Kim The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis Proc Natl Acad Sci U S A 107 2010 8248 8253
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
-
10
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
L. Lu, Y. Li, S.M. Kim Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver Proc Natl Acad Sci U S A 107 2010 1437 1442
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
-
11
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
D. Zhou, C. Conrad, F. Xia Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene Cancer Cell 16 2009 425 438
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
-
12
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
M. Cordenonsi, F. Zanconato, L. Azzolin The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells Cell 147 2011 759 772
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
-
13
-
-
33747072601
-
Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms
-
M.C. Cantarini, S.M. de la Monte, M. Pang Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms Hepatology 44 2006 446 457
-
(2006)
Hepatology
, vol.44
, pp. 446-457
-
-
Cantarini, M.C.1
De La Monte, S.M.2
Pang, M.3
-
14
-
-
0346365362
-
Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis
-
R. Qi, H. An, Y. Yu Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis Cancer Res 63 2003 8323 8329
-
(2003)
Cancer Res
, vol.63
, pp. 8323-8329
-
-
Qi, R.1
An, H.2
Yu, Y.3
-
15
-
-
67650236862
-
Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression
-
C. Wang, R. Qi, N. Li Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression J Biol Chem 284 2009 16183 16190
-
(2009)
J Biol Chem
, vol.284
, pp. 16183-16190
-
-
Wang, C.1
Qi, R.2
Li, N.3
-
16
-
-
84861573132
-
Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma
-
X.Q. Wang, W. Zhang, E.L. Lui Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma Int J Cancer 131 2012 E163 E172
-
(2012)
Int J Cancer
, vol.131
-
-
Wang, X.Q.1
Zhang, W.2
Lui, E.L.3
-
17
-
-
60749112337
-
YAP: At the crossroad between transformation and tumor suppression
-
E. Bertini, T. Oka, M. Sudol YAP: at the crossroad between transformation and tumor suppression Cell Cycle 8 2009 49 57
-
(2009)
Cell Cycle
, vol.8
, pp. 49-57
-
-
Bertini, E.1
Oka, T.2
Sudol, M.3
-
18
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
B. Zhao, X. Ye, J. Yu TEAD mediates YAP-dependent gene induction and growth control Genes Dev 22 2008 1962 1971
-
(2008)
Genes Dev
, vol.22
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
-
19
-
-
84862605178
-
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
-
Y. Liu-Chittenden, B. Huang, J.S. Shim Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP Genes Dev 26 2012 1300 1305
-
(2012)
Genes Dev
, vol.26
, pp. 1300-1305
-
-
Liu-Chittenden, Y.1
Huang, B.2
Shim, J.S.3
-
20
-
-
59149088576
-
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
-
B. Zhao, J. Kim, X. Ye Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein Cancer Res 69 2009 1089 1098
-
(2009)
Cancer Res
, vol.69
, pp. 1089-1098
-
-
Zhao, B.1
Kim, J.2
Ye, X.3
-
21
-
-
83755195660
-
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
-
D. Zhou, Y. Zhang, H. Wu Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance Proc Natl Acad Sci U S A 108 2011 E1312 E1320
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
-
-
Zhou, D.1
Zhang, Y.2
Wu, H.3
-
22
-
-
65549140672
-
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer
-
V. Rodilla, A. Villanueva, A. Obrador-Hevia Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer Proc Natl Acad Sci U S A 106 2009 6315 6320
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 6315-6320
-
-
Rodilla, V.1
Villanueva, A.2
Obrador-Hevia, A.3
-
23
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
J. Zhang, J.Y. Ji, M. Yu YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway Nat Cell Biol 11 2009 1444 1450
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
Ji, J.Y.2
Yu, M.3
-
24
-
-
33749125438
-
Delineation of a Fat tumor suppressor pathway
-
E. Cho, Y. Feng, C. Rauskolb Delineation of a Fat tumor suppressor pathway Nat Genet 38 2006 1142 1150
-
(2006)
Nat Genet
, vol.38
, pp. 1142-1150
-
-
Cho, E.1
Feng, Y.2
Rauskolb, C.3
-
25
-
-
78649969033
-
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway
-
X. Varelas, P. Samavarchi-Tehrani, M. Narimatsu The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway Dev Cell 19 2010 831 844
-
(2010)
Dev Cell
, vol.19
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
-
26
-
-
77955909174
-
Merlin in organ size control and tumorigenesis: Hippo versus EGFR?
-
C. Yi, J.L. Kissil Merlin in organ size control and tumorigenesis: hippo versus EGFR? Genes Dev 24 2010 1673 1679
-
(2010)
Genes Dev
, vol.24
, pp. 1673-1679
-
-
Yi, C.1
Kissil, J.L.2
-
27
-
-
72549090299
-
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
-
L.A. Fernandez, P.A. Northcott, J. Dalton YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation Genes Dev 23 2009 2729 2741
-
(2009)
Genes Dev
, vol.23
, pp. 2729-2741
-
-
Fernandez, L.A.1
Northcott, P.A.2
Dalton, J.3
-
28
-
-
82455210238
-
Connective tissue growth factor autocriny in human hepatocellular carcinoma: Oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation
-
R. Urtasun, M.U. Latasa, M.I. Demartis Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation Hepatology 54 2011 2149 2158
-
(2011)
Hepatology
, vol.54
, pp. 2149-2158
-
-
Urtasun, R.1
Latasa, M.U.2
Demartis, M.I.3
-
29
-
-
80555154065
-
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
-
P. Viatour, U. Ehmer, L.A. Saddic Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway J Exp Med 208 2011 1963 1976
-
(2011)
J Exp Med
, vol.208
, pp. 1963-1976
-
-
Viatour, P.1
Ehmer, U.2
Saddic, L.A.3
-
30
-
-
84856264859
-
IKKalpha activation of NOTCH links tumorigenesis via FOXA2 suppression
-
M. Liu, D.F. Lee, C.T. Chen IKKalpha activation of NOTCH links tumorigenesis via FOXA2 suppression Mol Cell 45 2012 171 184
-
(2012)
Mol Cell
, vol.45
, pp. 171-184
-
-
Liu, M.1
Lee, D.F.2
Chen, C.T.3
-
31
-
-
84864773126
-
Cholangiocarcinomas can originate from hepatocytes in mice
-
B. Fan, Y. Malato, D.F. Calvisi Cholangiocarcinomas can originate from hepatocytes in mice J Clin Invest 122 2012 2911 2915
-
(2012)
J Clin Invest
, vol.122
, pp. 2911-2915
-
-
Fan, B.1
Malato, Y.2
Calvisi, D.F.3
-
32
-
-
84869774410
-
Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice
-
A. Villanueva, C. Alsinet, K. Yanger Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice Gastroenterology 143 2012 1660 1669
-
(2012)
Gastroenterology
, vol.143
, pp. 1660-1669
-
-
Villanueva, A.1
Alsinet, C.2
Yanger, K.3
-
33
-
-
79955460636
-
Notch signalling in solid tumours: A little bit of everything but not all the time
-
P. Ranganathan, K.L. Weaver, A.J. Capobianco Notch signalling in solid tumours: a little bit of everything but not all the time Nat Rev Cancer 11 2011 338 351
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 338-351
-
-
Ranganathan, P.1
Weaver, K.L.2
Capobianco, A.J.3
-
34
-
-
84859614232
-
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
-
L. Boulter, O. Govaere, T.G. Bird Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease Nat Med 18 2012 572 579
-
(2012)
Nat Med
, vol.18
, pp. 572-579
-
-
Boulter, L.1
Govaere, O.2
Bird, T.G.3
-
35
-
-
84876145364
-
Constitutive Notch2 signaling induces hepatic tumors in mice
-
M.T. Dill, L. Tornillo, T. Fritzius Constitutive Notch2 signaling induces hepatic tumors in mice Hepatology 57 2012 1607 1619
-
(2012)
Hepatology
, vol.57
, pp. 1607-1619
-
-
Dill, M.T.1
Tornillo, L.2
Fritzius, T.3
-
36
-
-
76149134716
-
Structural basis of YAP recognition by TEAD4 in the hippo pathway
-
L. Chen, S.W. Chan, X. Zhang Structural basis of YAP recognition by TEAD4 in the hippo pathway Genes Dev 24 2010 290 300
-
(2010)
Genes Dev
, vol.24
, pp. 290-300
-
-
Chen, L.1
Chan, S.W.2
Zhang, X.3
-
37
-
-
47149111583
-
Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis
-
T. Nussbaum, J. Samarin, V. Ehemann Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis Hepatology 48 2008 146 156
-
(2008)
Hepatology
, vol.48
, pp. 146-156
-
-
Nussbaum, T.1
Samarin, J.2
Ehemann, V.3
-
38
-
-
77950356060
-
Glycoprotein 130-dependent pathways in host hepatocytes are important for liver repopulation in mice
-
D.F. Tschaharganeh, M. Kaldenbach, S. Erschfeld Glycoprotein 130-dependent pathways in host hepatocytes are important for liver repopulation in mice Liver Transpl 16 2010 23 32
-
(2010)
Liver Transpl
, vol.16
, pp. 23-32
-
-
Tschaharganeh, D.F.1
Kaldenbach, M.2
Erschfeld, S.3
-
39
-
-
70449671729
-
Direct inhibition of the NOTCH transcription factor complex
-
R.E. Moellering, M. Cornejo, T.N. Davis Direct inhibition of the NOTCH transcription factor complex Nature 462 2009 182 188
-
(2009)
Nature
, vol.462
, pp. 182-188
-
-
Moellering, R.E.1
Cornejo, M.2
Davis, T.N.3
-
40
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
F.D. Camargo, S. Gokhale, J.B. Johnnidis YAP1 increases organ size and expands undifferentiated progenitor cells Curr Biol 17 2007 2054 2060
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
-
41
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
J.S. Lee, I.S. Chu, J. Heo Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling Hepatology 40 2004 667 676
-
(2004)
Hepatology
, vol.40
, pp. 667-676
-
-
Lee, J.S.1
Chu, I.S.2
Heo, J.3
-
42
-
-
79952312698
-
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
-
D.F. Calvisi, C. Wang, C. Ho Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma Gastroenterology 140 2011 1071 1083
-
(2011)
Gastroenterology
, vol.140
, pp. 1071-1083
-
-
Calvisi, D.F.1
Wang, C.2
Ho, C.3
-
43
-
-
70350057051
-
Overexpression of far upstream element binding proteins: A mechanism regulating proliferation and migration in liver cancer cells
-
M. Malz, A. Weber, S. Singer Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells Hepatology 50 2009 1130 1139
-
(2009)
Hepatology
, vol.50
, pp. 1130-1139
-
-
Malz, M.1
Weber, A.2
Singer, S.3
-
44
-
-
48749122338
-
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma
-
M.N. Wente, M.M. Gaida, C. Mayer Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma Int J Oncol 33 2008 297 308
-
(2008)
Int J Oncol
, vol.33
, pp. 297-308
-
-
Wente, M.N.1
Gaida, M.M.2
Mayer, C.3
-
45
-
-
34548770025
-
Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis
-
S. Singer, V. Ehemann, A. Brauckhoff Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis Hepatology 46 2007 759 768
-
(2007)
Hepatology
, vol.46
, pp. 759-768
-
-
Singer, S.1
Ehemann, V.2
Brauckhoff, A.3
-
46
-
-
57549089243
-
Using TESS to predict transcription factor binding sites in DNA sequence
-
Chapter 2:Unit 2
-
J. Schug Using TESS to predict transcription factor binding sites in DNA sequence Curr Protoc Bioinformatics 2008 Chapter 2:Unit 2
-
(2008)
Curr Protoc Bioinformatics
-
-
Schug, J.1
|