-
1
-
-
33846094306
-
An enhanced MITOMAP with a global mtDNA mutational phylogeny
-
E. Ruiz-Pesini, M.T. Lott, V. Procaccio, J.C. Poole, M.C. Brandon, D. Mishmar, C. Yi, J. Kreuziger, P. Baldi, and D.C. Wallace An enhanced MITOMAP with a global mtDNA mutational phylogeny Nucleic Acids Res. 35 2007 D823 D828
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. D823-D828
-
-
Ruiz-Pesini, E.1
Lott, M.T.2
Procaccio, V.3
Poole, J.C.4
Brandon, M.C.5
Mishmar, D.6
Yi, C.7
Kreuziger, J.8
Baldi, P.9
Wallace, D.C.10
-
2
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in ageing
-
I. Trounce, E. Byrne, and S. Marzuki Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing Lancet 1 1989 637 639
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
3
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
A. Bender, K.J. Krishnan, C.M. Morris, G.A. Taylor, A.K. Reeve, R.H. Perry, E. Jaros, J.S. Hersheson, J. Betts, T. Klopstock, R.W. Taylor, and D.M. Turnbull High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nat. Genet. 38 2006 515 517
-
(2006)
Nat. Genet.
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
5
-
-
65449139544
-
Mitochondria, calcium and cell death: A deadly triad in neurodegeneration
-
F. Celsi, P. Pizzo, M. Brini, S. Leo, C. Fotino, P. Pinton, and R. Rizzuto Mitochondria, calcium and cell death: a deadly triad in neurodegeneration Biochim. Biophys. Acta 1787 2009 335 344
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 335-344
-
-
Celsi, F.1
Pizzo, P.2
Brini, M.3
Leo, S.4
Fotino, C.5
Pinton, P.6
Rizzuto, R.7
-
6
-
-
0344413426
-
Mitochondrial fission in apoptosis, neurodegeneration and aging
-
E. Bossy-Wetzel, M.J. Barsoum, A. Godzik, R. Schwarzenbacher, and S.A. Lipton Mitochondrial fission in apoptosis, neurodegeneration and aging Curr. Opin. Cell Biol. 15 2003 706 716
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 706-716
-
-
Bossy-Wetzel, E.1
Barsoum, M.J.2
Godzik, A.3
Schwarzenbacher, R.4
Lipton, S.A.5
-
7
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
M.F. Beal Mitochondria take center stage in aging and neurodegeneration Ann. Neurol. 58 2005 495 505
-
(2005)
Ann. Neurol.
, vol.58
, pp. 495-505
-
-
Beal, M.F.1
-
8
-
-
84884416043
-
Germline mitochondrial DNA mutations aggravate ageing and can impair brain development
-
J.M. Ross, J.B. Stewart, E. Hagstrom, S. Brene, A. Mourier, G. Coppotelli, C. Freyer, M. Lagouge, B.J. Hoffer, L. Olson, and N.G. Larsson Germline mitochondrial DNA mutations aggravate ageing and can impair brain development Nature 501 2013 412 415
-
(2013)
Nature
, vol.501
, pp. 412-415
-
-
Ross, J.M.1
Stewart, J.B.2
Hagstrom, E.3
Brene, S.4
Mourier, A.5
Coppotelli, G.6
Freyer, C.7
Lagouge, M.8
Hoffer, B.J.9
Olson, L.10
Larsson, N.G.11
-
9
-
-
0032576724
-
Energy transduction in ATP synthase
-
T. Elston, H. Wang, and G. Oster Energy transduction in ATP synthase Nature 391 1998 510 513
-
(1998)
Nature
, vol.391
, pp. 510-513
-
-
Elston, T.1
Wang, H.2
Oster, G.3
-
10
-
-
0035910414
-
The rotary machine in the cell, ATP synthase
-
H. Noji, and M. Yoshida The rotary machine in the cell, ATP synthase J. Biol. Chem. 276 2001 1665 1668
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1665-1668
-
-
Noji, H.1
Yoshida, M.2
-
11
-
-
0032868141
-
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
-
R.M. Andrews, I. Kubacka, P.F. Chinnery, R.N. Lightowlers, D.M. Turnbull, and N. Howell Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA Nat. Genet. 23 1999 147
-
(1999)
Nat. Genet.
, vol.23
, pp. 147
-
-
Andrews, R.M.1
Kubacka, I.2
Chinnery, P.F.3
Lightowlers, R.N.4
Turnbull, D.M.5
Howell, N.6
-
12
-
-
0026554863
-
Counting target molecules by exponential polymerase chain reaction: Copy number of mitochondrial DNA in rat tissues
-
R.J. Wiesner, J.C. Ruegg, and I. Morano Counting target molecules by exponential polymerase chain reaction: copy number of mitochondrial DNA in rat tissues Biochem. Biophys. Res. Commun. 183 1992 553 559
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.183
, pp. 553-559
-
-
Wiesner, R.J.1
Ruegg, J.C.2
Morano, I.3
-
13
-
-
0035895505
-
The sequence of the human genome
-
J.C. Venter, M.D. Adams, E.W. Myers, P.W. Li, R.J. Mural, G.G. Sutton, H.O. Smith, M. Yandell, C.A. Evans, R.A. Holt, J.D. Gocayne, P. Amanatides, R.M. Ballew, D.H. Huson, J.R. Wortman, Q. Zhang, C.D. Kodira, X.H. Zheng, L. Chen, M. Skupski, G. Subramanian, P.D. Thomas, J. Zhang, G.L. Gabor Miklos, C. Nelson, S. Broder, A.G. Clark, J. Nadeau, V.A. McKusick, N. Zinder, A.J. Levine, R.J. Roberts, M. Simon, C. Slayman, M. Hunkapiller, R. Bolanos, A. Delcher, I. Dew, D. Fasulo, M. Flanigan, L. Florea, A. Halpern, S. Hannenhalli, S. Kravitz, S. Levy, C. Mobarry, K. Reinert, K. Remington, J. Abu-Threideh, E. Beasley, K. Biddick, V. Bonazzi, R. Brandon, M. Cargill, I. Chandramouliswaran, R. Charlab, K. Chaturvedi, Z. Deng, V. Di Francesco, P. Dunn, K. Eilbeck, C. Evangelista, A.E. Gabrielian, W. Gan, W. Ge, F. Gong, Z. Gu, P. Guan, T.J. Heiman, M.E. Higgins, R.R. Ji, Z. Ke, K.A. Ketchum, Z. Lai, Y. Lei, Z. Li, J. Li, Y. Liang, X. Lin, F. Lu, G.V. Merkulov, N. Milshina, H.M. Moore, A.K. Naik, V.A. Narayan, B. Neelam, D. Nusskern, D.B. Rusch, S. Salzberg, W. Shao, B. Shue, J. Sun, Z. Wang, A. Wang, X. Wang, J. Wang, M. Wei, R. Wides, C. Xiao, C. Yan, A. Yao, J. Ye, M. Zhan, W. Zhang, H. Zhang, Q. Zhao, L. Zheng, F. Zhong, W. Zhong, S. Zhu, S. Zhao, D. Gilbert, S. Baumhueter, G. Spier, C. Carter, A. Cravchik, T. Woodage, F. Ali, H. An, A. Awe, D. Baldwin, H. Baden, M. Barnstead, I. Barrow, K. Beeson, D. Busam, A. Carver, A. Center, M.L. Cheng, L. Curry, S. Danaher, L. Davenport, R. Desilets, S. Dietz, K. Dodson, L. Doup, S. Ferriera, N. Garg, A. Gluecksmann, B. Hart, J. Haynes, C. Haynes, C. Heiner, S. Hladun, D. Hostin, J. Houck, T. Howland, C. Ibegwam, J. Johnson, F. Kalush, L. Kline, S. Koduru, A. Love, F. Mann, D. May, S. McCawley, T. McIntosh, I. McMullen, M. Moy, L. Moy, B. Murphy, K. Nelson, C. Pfannkoch, E. Pratts, V. Puri, H. Qureshi, M. Reardon, R. Rodriguez, Y.H. Rogers, D. Romblad, B. Ruhfel, R. Scott, C. Sitter, M. Smallwood, E. Stewart, R. Strong, E. Suh, R. Thomas, N.N. Tint, S. Tse, C. Vech, G. Wang, J. Wetter, S. Williams, M. Williams, S. Windsor, E. Winn-Deen, K. Wolfe, J. Zaveri, K. Zaveri, J.F. Abril, R. Guigo, M.J. Campbell, K.V. Sjolander, B. Karlak, A. Kejariwal, H. Mi, B. Lazareva, T. Hatton, A. Narechania, K. Diemer, A. Muruganujan, N. Guo, S. Sato, V. Bafna, S. Istrail, R. Lippert, R. Schwartz, B. Walenz, S. Yooseph, D. Allen, A. Basu, J. Baxendale, L. Blick, M. Caminha, J. Carnes-Stine, P. Caulk, Y.H. Chiang, M. Coyne, C. Dahlke, A. Mays, M. Dombroski, M. Donnelly, D. Ely, S. Esparham, C. Fosler, H. Gire, S. Glanowski, K. Glasser, A. Glodek, M. Gorokhov, K. Graham, B. Gropman, M. Harris, J. Heil, S. Henderson, J. Hoover, D. Jennings, C. Jordan, J. Jordan, J. Kasha, L. Kagan, C. Kraft, A. Levitsky, M. Lewis, X. Liu, J. Lopez, D. Ma, W. Majoros, J. McDaniel, S. Murphy, M. Newman, T. Nguyen, N. Nguyen, M. Nodell, S. Pan, J. Peck, M. Peterson, W. Rowe, R. Sanders, J. Scott, M. Simpson, T. Smith, A. Sprague, T. Stockwell, R. Turner, E. Venter, M. Wang, M. Wen, D. Wu, M. Wu, A. Xia, A. Zandieh, and X. Zhu The sequence of the human genome Science 291 2001 1304 1351
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
Broder, S.26
Clark, A.G.27
Nadeau, J.28
McKusick, V.A.29
Zinder, N.30
Levine, A.J.31
Roberts, R.J.32
Simon, M.33
Slayman, C.34
Hunkapiller, M.35
Bolanos, R.36
Delcher, A.37
Dew, I.38
Fasulo, D.39
Flanigan, M.40
Florea, L.41
Halpern, A.42
Hannenhalli, S.43
Kravitz, S.44
Levy, S.45
Mobarry, C.46
Reinert, K.47
Remington, K.48
Abu-Threideh, J.49
Beasley, E.50
Biddick, K.51
Bonazzi, V.52
Brandon, R.53
Cargill, M.54
Chandramouliswaran, I.55
Charlab, R.56
Chaturvedi, K.57
Deng, Z.58
Di Francesco, V.59
Dunn, P.60
Eilbeck, K.61
Evangelista, C.62
Gabrielian, A.E.63
Gan, W.64
Ge, W.65
Gong, F.66
Gu, Z.67
Guan, P.68
Heiman, T.J.69
Higgins, M.E.70
Ji, R.R.71
Ke, Z.72
Ketchum, K.A.73
Lai, Z.74
Lei, Y.75
Li, Z.76
Li, J.77
Liang, Y.78
Lin, X.79
Lu, F.80
Merkulov, G.V.81
Milshina, N.82
Moore, H.M.83
Naik, A.K.84
Narayan, V.A.85
Neelam, B.86
Nusskern, D.87
Rusch, D.B.88
Salzberg, S.89
Shao, W.90
Shue, B.91
Sun, J.92
Wang, Z.93
Wang, A.94
Wang, X.95
Wang, J.96
Wei, M.97
Wides, R.98
Xiao, C.99
more..
-
14
-
-
84864308607
-
Mitochondrial DNA nucleoid structure
-
D.F. Bogenhagen Mitochondrial DNA nucleoid structure Biochim. Biophys. Acta 1819 2012 914 920
-
(2012)
Biochim. Biophys. Acta
, vol.1819
, pp. 914-920
-
-
Bogenhagen, D.F.1
-
15
-
-
74549114163
-
Hungry codons promote frameshifting in human mitochondrial ribosomes
-
R. Temperley, R. Richter, S. Dennerlein, R.N. Lightowlers, and Z.M. Chrzanowska-Lightowlers Hungry codons promote frameshifting in human mitochondrial ribosomes Science 327 2010 301
-
(2010)
Science
, vol.327
, pp. 301
-
-
Temperley, R.1
Richter, R.2
Dennerlein, S.3
Lightowlers, R.N.4
Chrzanowska-Lightowlers, Z.M.5
-
17
-
-
17744393686
-
Mitochondrial DNA mutations in human disease
-
R.W. Taylor, and D.M. Turnbull Mitochondrial DNA mutations in human disease Nat. Rev. Genet. 6 2005 389 402
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 389-402
-
-
Taylor, R.W.1
Turnbull, D.M.2
-
18
-
-
64049089255
-
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
-
M. van Oven, and M. Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation Hum. Mutat. 30 2009 E386 E394
-
(2009)
Hum. Mutat.
, vol.30
, pp. E386-E394
-
-
Van Oven, M.1
Kayser, M.2
-
19
-
-
0346455087
-
The mutation rate in the human mtDNA control region
-
S. Sigurgardottir, A. Helgason, J.R. Gulcher, K. Stefansson, and P. Donnelly The mutation rate in the human mtDNA control region Am. J. Hum. Genet. 66 2000 1599 1609
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1599-1609
-
-
Sigurgardottir, S.1
Helgason, A.2
Gulcher, J.R.3
Stefansson, K.4
Donnelly, P.5
-
20
-
-
0027363388
-
Asian affinities and continental radiation of the four founding Native American mtDNAs
-
A. Torroni, T.G. Schurr, M.F. Cabell, M.D. Brown, J.V. Neel, M. Larsen, D.G. Smith, C.M. Vullo, and D.C. Wallace Asian affinities and continental radiation of the four founding Native American mtDNAs Am. J. Hum. Genet. 53 1993 563 590
-
(1993)
Am. J. Hum. Genet.
, vol.53
, pp. 563-590
-
-
Torroni, A.1
Schurr, T.G.2
Cabell, M.F.3
Brown, M.D.4
Neel, J.V.5
Larsen, M.6
Smith, D.G.7
Vullo, C.M.8
Wallace, D.C.9
-
22
-
-
61649121108
-
Mitochondrial DNA haplogroups J and K are not protective for Parkinson's disease in the Australian community
-
P. Mehta, G.D. Mellick, D.B. Rowe, G.M. Halliday, M.M. Jones, N. Manwaring, H. Vandebona, P.A. Silburn, J.J. Wang, P. Mitchell, and C.M. Sue Mitochondrial DNA haplogroups J and K are not protective for Parkinson's disease in the Australian community Mov. Disord. 24 2009 290 292
-
(2009)
Mov. Disord.
, vol.24
, pp. 290-292
-
-
Mehta, P.1
Mellick, G.D.2
Rowe, D.B.3
Halliday, G.M.4
Jones, M.M.5
Manwaring, N.6
Vandebona, H.7
Silburn, P.A.8
Wang, J.J.9
Mitchell, P.10
Sue, C.M.11
-
23
-
-
41549121974
-
Mitochondrial DNA polymorphisms and haplogroups in Parkinson's disease and control individuals with a similar genetic background
-
H. Latsoudis, C. Spanaki, G. Chlouverakis, and A. Plaitakis Mitochondrial DNA polymorphisms and haplogroups in Parkinson's disease and control individuals with a similar genetic background J. Hum. Genet. 53 2008 349 356
-
(2008)
J. Hum. Genet.
, vol.53
, pp. 349-356
-
-
Latsoudis, H.1
Spanaki, C.2
Chlouverakis, G.3
Plaitakis, A.4
-
24
-
-
20544461885
-
Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians
-
D. Ghezzi, C. Marelli, A. Achilli, S. Goldwurm, G. Pezzoli, P. Barone, M.T. Pellecchia, P. Stanzione, L. Brusa, A.R. Bentivoglio, U. Bonuccelli, L. Petrozzi, G. Abbruzzese, R. Marchese, P. Cortelli, D. Grimaldi, P. Martinelli, C. Ferrarese, B. Garavaglia, S. Sangiorgi, V. Carelli, A. Torroni, A. Albanese, and M. Zeviani Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians Eur. J. Hum. Genet. 13 2005 748 752
-
(2005)
Eur. J. Hum. Genet.
, vol.13
, pp. 748-752
-
-
Ghezzi, D.1
Marelli, C.2
Achilli, A.3
Goldwurm, S.4
Pezzoli, G.5
Barone, P.6
Pellecchia, M.T.7
Stanzione, P.8
Brusa, L.9
Bentivoglio, A.R.10
Bonuccelli, U.11
Petrozzi, L.12
Abbruzzese, G.13
Marchese, R.14
Cortelli, P.15
Grimaldi, D.16
Martinelli, P.17
Ferrarese, C.18
Garavaglia, B.19
Sangiorgi, S.20
Carelli, V.21
Torroni, A.22
Albanese, A.23
Zeviani, M.24
more..
-
25
-
-
34447265267
-
Lack of association between mtDNA haplogroups and Alzheimer's disease in Tuscany
-
M. Mancuso, M. Nardini, D. Micheli, A. Rocchi, C. Nesti, N.J. Giglioli, L. Petrozzi, C. Rossi, R. Ceravolo, A. Bacci, A. Choub, G. Ricci, G. Tognoni, M.L. Manca, G. Siciliano, and L. Murri Lack of association between mtDNA haplogroups and Alzheimer's disease in Tuscany Neurol. Sci. 28 2007 142 147
-
(2007)
Neurol. Sci.
, vol.28
, pp. 142-147
-
-
Mancuso, M.1
Nardini, M.2
Micheli, D.3
Rocchi, A.4
Nesti, C.5
Giglioli, N.J.6
Petrozzi, L.7
Rossi, C.8
Ceravolo, R.9
Bacci, A.10
Choub, A.11
Ricci, G.12
Tognoni, G.13
Manca, M.L.14
Siciliano, G.15
Murri, L.16
-
26
-
-
77954034861
-
I. Alzheimer's Disease Neuroimaging, Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort
-
A. Lakatos, O. Derbeneva, D. Younes, D. Keator, T. Bakken, M. Lvova, M. Brandon, G. Guffanti, D. Reglodi, A. Saykin, M. Weiner, F. Macciardi, N. Schork, D.C. Wallace, and S.G. Potkin I. Alzheimer's Disease Neuroimaging, Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort Neurobiol. Aging 31 2010 1355 1363
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 1355-1363
-
-
Lakatos, A.1
Derbeneva, O.2
Younes, D.3
Keator, D.4
Bakken, T.5
Lvova, M.6
Brandon, M.7
Guffanti, G.8
Reglodi, D.9
Saykin, A.10
Weiner, M.11
MacCiardi, F.12
Schork, N.13
Wallace, D.C.14
Potkin, S.G.15
-
27
-
-
84866443759
-
Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging
-
P.G. Ridge, T.J. Maxwell, C.D. Corcoran, M.C. Norton, J.T. Tschanz, E. O'Brien, R.A. Kerber, R.M. Cawthon, R.G. Munger, and J.S. Kauwe Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging PLoS One 7 2012 e45134
-
(2012)
PLoS One
, vol.7
, pp. e45134
-
-
Ridge, P.G.1
Maxwell, T.J.2
Corcoran, C.D.3
Norton, M.C.4
Tschanz, J.T.5
O'Brien, E.6
Kerber, R.A.7
Cawthon, R.M.8
Munger, R.G.9
Kauwe, J.S.10
-
28
-
-
77950662782
-
Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: A genetic association study
-
P.F. Chinnery, H.R. Elliott, A. Syed, P.M. Rothwell, and S. Oxford Vascular Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: a genetic association study Lancet Neurol 9 2010 498 503
-
(2010)
Lancet Neurol
, vol.9
, pp. 498-503
-
-
Chinnery, P.F.1
Elliott, H.R.2
Syed, A.3
Rothwell, P.M.4
Oxford Vascular, S.5
-
29
-
-
84861593887
-
Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis
-
C.J. Ingram, M.E. Weale, C.A. Plaster, K.E. Morrison, E.F. Goodall, H.S. Pall, M. Beck, S. Jablonka, M. Sendtner, E.M. Fisher, N. Bradman, and D. Kasperaviciute Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis Amyotroph. Lateral Scler. 13 2012 341 346
-
(2012)
Amyotroph. Lateral Scler.
, vol.13
, pp. 341-346
-
-
Ingram, C.J.1
Weale, M.E.2
Plaster, C.A.3
Morrison, K.E.4
Goodall, E.F.5
Pall, H.S.6
Beck, M.7
Jablonka, S.8
Sendtner, M.9
Fisher, E.M.10
Bradman, N.11
Kasperaviciute, D.12
-
30
-
-
49549089537
-
No evidence of association between frontotemporal dementia and major European mtDNA haplogroups
-
G. Rose, T. Longo, R. Maletta, G. Passarino, A.C. Bruni, and G. De Benedictis No evidence of association between frontotemporal dementia and major European mtDNA haplogroups Eur. J. Neurol. 15 2008 1006 1008
-
(2008)
Eur. J. Neurol.
, vol.15
, pp. 1006-1008
-
-
Rose, G.1
Longo, T.2
Maletta, R.3
Passarino, G.4
Bruni, A.C.5
De Benedictis, G.6
-
31
-
-
48249095920
-
Single-strand break repair and genetic disease
-
K.W. Caldecott Single-strand break repair and genetic disease Nat. Rev. Genet. 9 2008 619 631
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 619-631
-
-
Caldecott, K.W.1
-
32
-
-
0028901020
-
Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage
-
K.G. Pinz, S. Shibutani, and D.F. Bogenhagen Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage J. Biol. Chem. 270 1995 9202 9206
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9202-9206
-
-
Pinz, K.G.1
Shibutani, S.2
Bogenhagen, D.F.3
-
33
-
-
84902989327
-
Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans
-
H.L. Baines, J.B. Stewart, C. Stamp, A. Zupanic, T.B. Kirkwood, N.G. Larsson, D.M. Turnbull, and L.C. Greaves Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans Mech. Ageing Dev. 139 2014 22 30
-
(2014)
Mech. Ageing Dev.
, vol.139
, pp. 22-30
-
-
Baines, H.L.1
Stewart, J.B.2
Stamp, C.3
Zupanic, A.4
Kirkwood, T.B.5
Larsson, N.G.6
Turnbull, D.M.7
Greaves, L.C.8
-
34
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, Y.M. Bohlooly, S. Gidlof, A. Oldfors, R. Wibom, J. Tornell, H.T. Jacobs, and N.G. Larsson Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
35
-
-
38949091096
-
Strong purifying selection in transmission of mammalian mitochondrial DNA
-
J.B. Stewart, C. Freyer, J.L. Elson, A. Wredenberg, Z. Cansu, A. Trifunovic, and N.G. Larsson Strong purifying selection in transmission of mammalian mitochondrial DNA PLoS Biol. 6 2008 e10
-
(2008)
PLoS Biol.
, vol.6
, pp. e10
-
-
Stewart, J.B.1
Freyer, C.2
Elson, J.L.3
Wredenberg, A.4
Cansu, Z.5
Trifunovic, A.6
Larsson, N.G.7
-
36
-
-
79952426030
-
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
-
D. Simsek, A. Furda, Y. Gao, J. Artus, E. Brunet, A.K. Hadjantonakis, B. Van Houten, S. Shuman, P.J. McKinnon, and M. Jasin Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair Nature 471 2011 245 248
-
(2011)
Nature
, vol.471
, pp. 245-248
-
-
Simsek, D.1
Furda, A.2
Gao, Y.3
Artus, J.4
Brunet, E.5
Hadjantonakis, A.K.6
Van Houten, B.7
Shuman, S.8
McKinnon, P.J.9
Jasin, M.10
-
37
-
-
70450277835
-
Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity
-
M.N. Rossi, M. Carbone, C. Mostocotto, C. Mancone, M. Tripodi, R. Maione, and P. Amati Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity J. Biol. Chem. 284 2009 31616 31624
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31616-31624
-
-
Rossi, M.N.1
Carbone, M.2
Mostocotto, C.3
Mancone, C.4
Tripodi, M.5
Maione, R.6
Amati, P.7
-
38
-
-
55049124777
-
Long patch base excision repair in mammalian mitochondrial genomes
-
B. Szczesny, A.W. Tann, M.J. Longley, W.C. Copeland, and S. Mitra Long patch base excision repair in mammalian mitochondrial genomes J. Biol. Chem. 283 2008 26349 26356
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26349-26356
-
-
Szczesny, B.1
Tann, A.W.2
Longley, M.J.3
Copeland, W.C.4
Mitra, S.5
-
39
-
-
0026598677
-
Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease
-
S. Kleff, B. Kemper, and R. Sternglanz Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease EMBO J. 11 1992 699 704
-
(1992)
EMBO J.
, vol.11
, pp. 699-704
-
-
Kleff, S.1
Kemper, B.2
Sternglanz, R.3
-
40
-
-
39749124232
-
What causes mitochondrial DNA deletions in human cells?
-
K.J. Krishnan, A.K. Reeve, D.C. Samuels, P.F. Chinnery, J.K. Blackwood, R.W. Taylor, S. Wanrooij, J.N. Spelbrink, R.N. Lightowlers, and D.M. Turnbull What causes mitochondrial DNA deletions in human cells? Nat. Genet. 40 2008 275 279
-
(2008)
Nat. Genet.
, vol.40
, pp. 275-279
-
-
Krishnan, K.J.1
Reeve, A.K.2
Samuels, D.C.3
Chinnery, P.F.4
Blackwood, J.K.5
Taylor, R.W.6
Wanrooij, S.7
Spelbrink, J.N.8
Lightowlers, R.N.9
Turnbull, D.M.10
-
41
-
-
84866729278
-
Minimizing the damage: Repair pathways keep mitochondrial DNA intact
-
L. Kazak, A. Reyes, and I.J. Holt Minimizing the damage: repair pathways keep mitochondrial DNA intact Nat. Rev. Mol. Cell Biol. 13 2012 659 671
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 659-671
-
-
Kazak, L.1
Reyes, A.2
Holt, I.J.3
-
42
-
-
0035097502
-
Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age
-
J.L. Elson, D.C. Samuels, D.M. Turnbull, and P.F. Chinnery Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age Am. J. Hum. Genet. 68 2001 802 806
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 802-806
-
-
Elson, J.L.1
Samuels, D.C.2
Turnbull, D.M.3
Chinnery, P.F.4
-
43
-
-
84871565767
-
Universal heteroplasmy of human mitochondrial DNA
-
B.A. Payne, I.J. Wilson, P. Yu-Wai-Man, J. Coxhead, D. Deehan, R. Horvath, R.W. Taylor, D.C. Samuels, M. Santibanez-Koref, and P.F. Chinnery Universal heteroplasmy of human mitochondrial DNA Hum. Mol. Genet. 22 2013 384 390
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 384-390
-
-
Payne, B.A.1
Wilson, I.J.2
Yu-Wai-Man, P.3
Coxhead, J.4
Deehan, D.5
Horvath, R.6
Taylor, R.W.7
Samuels, D.C.8
Santibanez-Koref, M.9
Chinnery, P.F.10
-
44
-
-
79960918493
-
The timing of mitochondrial DNA mutations in aging
-
K. Khrapko The timing of mitochondrial DNA mutations in aging Nat. Genet. 43 2011 726 727
-
(2011)
Nat. Genet.
, vol.43
, pp. 726-727
-
-
Khrapko, K.1
-
45
-
-
0024366601
-
Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - An age-related phenomenon. A histochemical ultracytochemical study
-
J. Muller-Hocker Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - an age-related phenomenon. A histochemical ultracytochemical study Am. J. Pathol. 134 1989 1167 1173
-
(1989)
Am. J. Pathol.
, vol.134
, pp. 1167-1173
-
-
Muller-Hocker, J.1
-
46
-
-
0025673968
-
Cytochrome c oxidase deficient fibres in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
-
J. Muller-Hocker Cytochrome c oxidase deficient fibres in the limb muscle and diaphragm of man without muscular disease: an age-related alteration J. Neurol. Sci. 100 1990 14 21
-
(1990)
J. Neurol. Sci.
, vol.100
, pp. 14-21
-
-
Muller-Hocker, J.1
-
47
-
-
0036258718
-
Ageing muscle: Clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function
-
G. Fayet, M. Jansson, D. Sternberg, A.R. Moslemi, P. Blondy, A. Lombes, M. Fardeau, and A. Oldfors Ageing muscle: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function Neuromuscul. Disord. 12 2002 484 493
-
(2002)
Neuromuscul. Disord.
, vol.12
, pp. 484-493
-
-
Fayet, G.1
Jansson, M.2
Sternberg, D.3
Moslemi, A.R.4
Blondy, P.5
Lombes, A.6
Fardeau, M.7
Oldfors, A.8
-
48
-
-
0037444769
-
Mitochondrial threshold effects
-
R. Rossignol, B. Faustin, C. Rocher, M. Malgat, J.P. Mazat, and T. Letellier Mitochondrial threshold effects Biochem. Med. 370 2003 751 762
-
(2003)
Biochem. Med.
, vol.370
, pp. 751-762
-
-
Rossignol, R.1
Faustin, B.2
Rocher, C.3
Malgat, M.4
Mazat, J.P.5
Letellier, T.6
-
49
-
-
0033584845
-
Threshold effect and tissue specificity. Implication for mitochondrial cytopathies
-
R. Rossignol, M. Malgat, J.P. Mazat, and T. Letellier Threshold effect and tissue specificity. Implication for mitochondrial cytopathies J. Biol. Chem. 274 1999 33426 33432
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33426-33432
-
-
Rossignol, R.1
Malgat, M.2
Mazat, J.P.3
Letellier, T.4
-
50
-
-
0025836655
-
Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction
-
J. Hayashi, S. Ohta, A. Kikuchi, M. Takemitsu, Y. Goto, and I. Nonaka Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction Proc. Natl. Acad. Sci. U. S. A. 88 1991 10614 10618
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 10614-10618
-
-
Hayashi, J.1
Ohta, S.2
Kikuchi, A.3
Takemitsu, M.4
Goto, Y.5
Nonaka, I.6
-
51
-
-
0026621445
-
Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF)
-
L. Boulet, G. Karpati, and E.A. Shoubridge Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF) Am. J. Hum. Genet. 51 1992 1187 1200
-
(1992)
Am. J. Hum. Genet.
, vol.51
, pp. 1187-1200
-
-
Boulet, L.1
Karpati, G.2
Shoubridge, E.A.3
-
52
-
-
0027992780
-
The relationship between mitochondrial genotype and mitochondrial phenotype in lymphoblasts with a heteroplasmic mtDNA deletion
-
J.N. Spelbrink, B.A. Van Oost, and C. Van den Bogert The relationship between mitochondrial genotype and mitochondrial phenotype in lymphoblasts with a heteroplasmic mtDNA deletion Hum. Mol. Genet. 3 1994 1989 1997
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1989-1997
-
-
Spelbrink, J.N.1
Van Oost, B.A.2
Van Den Bogert, C.3
-
53
-
-
0029790507
-
Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations
-
A.M. James, Y.H. Wei, C.Y. Pang, and M.P. Murphy Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations Biochem. J. 318 Pt 2 1996 401 407
-
(1996)
Biochem. J.
, vol.318
, pp. 401-407
-
-
James, A.M.1
Wei, Y.H.2
Pang, C.Y.3
Murphy, M.P.4
-
54
-
-
0035861593
-
In vivo regulation of oxidative phosphorylation in cells harboring a stop-codon mutation in mitochondrial DNA-encoded cytochrome c oxidase subunit i
-
M. D'Aurelio, F. Pallotti, A. Barrientos, C.D. Gajewski, J.Q. Kwong, C. Bruno, M.F. Beal, and G. Manfredi In vivo regulation of oxidative phosphorylation in cells harboring a stop-codon mutation in mitochondrial DNA-encoded cytochrome c oxidase subunit I J. Biol. Chem. 276 2001 46925 46932
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46925-46932
-
-
D'Aurelio, M.1
Pallotti, F.2
Barrientos, A.3
Gajewski, C.D.4
Kwong, J.Q.5
Bruno, C.6
Beal, M.F.7
Manfredi, G.8
-
55
-
-
0033971346
-
Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria
-
Y. Bai, R.M. Shakeley, and G. Attardi Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria Mol. Cell. Biol. 20 2000 805 815
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 805-815
-
-
Bai, Y.1
Shakeley, R.M.2
Attardi, G.3
-
56
-
-
0029059067
-
MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination
-
J.A. Enriquez, A. Chomyn, and G. Attardi MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination Nat. Genet. 10 1995 47 55
-
(1995)
Nat. Genet.
, vol.10
, pp. 47-55
-
-
Enriquez, J.A.1
Chomyn, A.2
Attardi, G.3
-
57
-
-
0025674177
-
Detection of a specific mitochondrial DNA deletion in tissues of older humans
-
G.A. Cortopassi, and N. Arnheim Detection of a specific mitochondrial DNA deletion in tissues of older humans Nucleic Acids Res. 18 1990 6927 6933
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6927-6933
-
-
Cortopassi, G.A.1
Arnheim, N.2
-
58
-
-
0025758425
-
Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia
-
K. Hattori, M. Tanaka, S. Sugiyama, T. Obayashi, T. Ito, T. Satake, Y. Hanaki, J. Asai, M. Nagano, and T. Ozawa Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia Am. Heart J. 121 1991 1735 1742
-
(1991)
Am. Heart J.
, vol.121
, pp. 1735-1742
-
-
Hattori, K.1
Tanaka, M.2
Sugiyama, S.3
Obayashi, T.4
Ito, T.5
Satake, T.6
Hanaki, Y.7
Asai, J.8
Nagano, M.9
Ozawa, T.10
-
60
-
-
0026340875
-
Deleted mitochondrial DNA in the skeletal muscle of aged individuals
-
M. Katayama, M. Tanaka, H. Yamamoto, T. Ohbayashi, Y. Nimura, and T. Ozawa Deleted mitochondrial DNA in the skeletal muscle of aged individuals Biochem. Int. 25 1991 47 56
-
(1991)
Biochem. Int.
, vol.25
, pp. 47-56
-
-
Katayama, M.1
Tanaka, M.2
Yamamoto, H.3
Ohbayashi, T.4
Nimura, Y.5
Ozawa, T.6
-
61
-
-
0026732706
-
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
-
G.A. Cortopassi, D. Shibata, N.W. Soong, and N. Arnheim A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues Proc. Natl. Acad. Sci. U. S. A. 89 1992 7370 7374
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 7370-7374
-
-
Cortopassi, G.A.1
Shibata, D.2
Soong, N.W.3
Arnheim, N.4
-
62
-
-
0026671245
-
Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease
-
M. Corral-Debrinski, J.M. Shoffner, M.T. Lott, and D.C. Wallace Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease Mutat. Res. 275 1992 169 180
-
(1992)
Mutat. Res.
, vol.275
, pp. 169-180
-
-
Corral-Debrinski, M.1
Shoffner, J.M.2
Lott, M.T.3
Wallace, D.C.4
-
63
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
J.M. Cooper, V.M. Mann, and A.H. Schapira Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing J. Neurol. Sci. 113 1992 91 98
-
(1992)
J. Neurol. Sci.
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.3
-
64
-
-
0024596946
-
A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA
-
E.A. Schon, R. Rizzuto, C.T. Moraes, H. Nakase, M. Zeviani, and S. DiMauro A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA Science 244 1989 346 349
-
(1989)
Science
, vol.244
, pp. 346-349
-
-
Schon, E.A.1
Rizzuto, R.2
Moraes, C.T.3
Nakase, H.4
Zeviani, M.5
DiMauro, S.6
-
65
-
-
0025373850
-
Transcription and translation of deleted mitochondrial genomes in Kearns-Sayre syndrome: Implications for pathogenesis
-
H. Nakase, C.T. Moraes, R. Rizzuto, A. Lombes, S. DiMauro, and E.A. Schon Transcription and translation of deleted mitochondrial genomes in Kearns-Sayre syndrome: implications for pathogenesis Am. J. Hum. Genet. 46 1990 418 427
-
(1990)
Am. J. Hum. Genet.
, vol.46
, pp. 418-427
-
-
Nakase, H.1
Moraes, C.T.2
Rizzuto, R.3
Lombes, A.4
DiMauro, S.5
Schon, E.A.6
-
66
-
-
0026907560
-
Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions
-
C.T. Moraes, E. Ricci, V. Petruzzella, S. Shanske, S. DiMauro, E.A. Schon, and E. Bonilla Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions Nat. Genet. 1 1992 359 367
-
(1992)
Nat. Genet.
, vol.1
, pp. 359-367
-
-
Moraes, C.T.1
Ricci, E.2
Petruzzella, V.3
Shanske, S.4
DiMauro, S.5
Schon, E.A.6
Bonilla, E.7
-
67
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
M. Corral-Debrinski, T. Horton, M.T. Lott, J.M. Shoffner, M.F. Beal, and D.C. Wallace Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age Nat. Genet. 2 1992 324 329
-
(1992)
Nat. Genet.
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
68
-
-
46749100918
-
The 4977 bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more?
-
C. Meissner, P. Bruse, S.A. Mohamed, A. Schulz, H. Warnk, T. Storm, and M. Oehmichen The 4977 bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: a useful biomarker or more? Exp. Gerontol. 43 2008 645 652
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 645-652
-
-
Meissner, C.1
Bruse, P.2
Mohamed, S.A.3
Schulz, A.4
Warnk, H.5
Storm, T.6
Oehmichen, M.7
-
69
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
N.W. Soong, D.R. Hinton, G. Cortopassi, and N. Arnheim Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain Nat. Genet. 2 1992 318 323
-
(1992)
Nat. Genet.
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
70
-
-
0031556536
-
Elevated levels of the Kearns-Sayre syndrome mitochondrial DNA deletion in temporal cortex of Alzheimer's patients
-
N.S. Hamblet, and F.J. Castora Elevated levels of the Kearns-Sayre syndrome mitochondrial DNA deletion in temporal cortex of Alzheimer's patients Mutat. Res. 379 1997 253 262
-
(1997)
Mutat. Res.
, vol.379
, pp. 253-262
-
-
Hamblet, N.S.1
Castora, F.J.2
-
71
-
-
77951978898
-
Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions
-
R. Gredilla, C. Garm, R. Holm, V.A. Bohr, and T. Stevnsner Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions Neurobiol. Aging 31 2010 993 1002
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 993-1002
-
-
Gredilla, R.1
Garm, C.2
Holm, R.3
Bohr, V.A.4
Stevnsner, T.5
-
72
-
-
84890797290
-
Mitochondrial DNA rearrangements in health and disease - A comprehensive study
-
J. Damas, D.C. Samuels, J. Carneiro, A. Amorim, and F. Pereira Mitochondrial DNA rearrangements in health and disease - a comprehensive study Hum. Mutat. 35 2014 1 14
-
(2014)
Hum. Mutat.
, vol.35
, pp. 1-14
-
-
Damas, J.1
Samuels, D.C.2
Carneiro, J.3
Amorim, A.4
Pereira, F.5
-
73
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Y. Kraytsberg, E. Kudryavtseva, A.C. McKee, C. Geula, N.W. Kowall, and K. Khrapko Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons Nat. Genet. 38 2006 518 520
-
(2006)
Nat. Genet.
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
74
-
-
38749102795
-
Nature of mitochondrial DNA deletions in substantia nigra neurons
-
A.K. Reeve, K.J. Krishnan, J.L. Elson, C.M. Morris, A. Bender, R.N. Lightowlers, and D.M. Turnbull Nature of mitochondrial DNA deletions in substantia nigra neurons Am. J. Hum. Genet. 82 2008 228 235
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 228-235
-
-
Reeve, A.K.1
Krishnan, K.J.2
Elson, J.L.3
Morris, C.M.4
Bender, A.5
Lightowlers, R.N.6
Turnbull, D.M.7
-
75
-
-
0035125774
-
Point mutations of the mtDNA control region in normal and neurodegenerative human brains
-
P.F. Chinnery, G.A. Taylor, N. Howell, D.T. Brown, T.J. Parsons, and D.M. Turnbull Point mutations of the mtDNA control region in normal and neurodegenerative human brains Am. J. Hum. Genet. 68 2001 529 532
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 529-532
-
-
Chinnery, P.F.1
Taylor, G.A.2
Howell, N.3
Brown, D.T.4
Parsons, T.J.5
Turnbull, D.M.6
-
76
-
-
0033595684
-
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
-
Y. Michikawa, F. Mazzucchelli, N. Bresolin, G. Scarlato, and G. Attardi Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication Science 286 1999 774 779
-
(1999)
Science
, vol.286
, pp. 774-779
-
-
Michikawa, Y.1
Mazzucchelli, F.2
Bresolin, N.3
Scarlato, G.4
Attardi, G.5
-
77
-
-
0035309740
-
Low mutational burden of individual acquired mitochondrial DNA mutations in brain
-
D.K. Simon, M.T. Lin, C.H. Ahn, G.J. Liu, G.E. Gibson, M.F. Beal, and D.R. Johns Low mutational burden of individual acquired mitochondrial DNA mutations in brain Genomics 73 2001 113 116
-
(2001)
Genomics
, vol.73
, pp. 113-116
-
-
Simon, D.K.1
Lin, M.T.2
Ahn, C.H.3
Liu, G.J.4
Gibson, G.E.5
Beal, M.F.6
Johns, D.R.7
-
78
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
M.T. Lin, D.K. Simon, C.H. Ahn, L.M. Kim, and M.F. Beal High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain Hum. Mol. Genet. 11 2002 133 145
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Beal, M.F.5
-
79
-
-
84884686924
-
Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage
-
S.R. Kennedy, J.J. Salk, M.W. Schmitt, and L.A. Loeb Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage PLoS Genet. 9 2013 e1003794
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003794
-
-
Kennedy, S.R.1
Salk, J.J.2
Schmitt, M.W.3
Loeb, L.A.4
-
80
-
-
0034637514
-
In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells
-
J.N. Spelbrink, J.M. Toivonen, G.A. Hakkaart, J.M. Kurkela, H.M. Cooper, S.K. Lehtinen, N. Lecrenier, J.W. Back, D. Speijer, F. Foury, and H.T. Jacobs In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells J. Biol. Chem. 275 2000 24818 24828
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24818-24828
-
-
Spelbrink, J.N.1
Toivonen, J.M.2
Hakkaart, G.A.3
Kurkela, J.M.4
Cooper, H.M.5
Lehtinen, S.K.6
Lecrenier, N.7
Back, J.W.8
Speijer, D.9
Foury, F.10
Jacobs, H.T.11
-
81
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
European Alzheimer's Disease, Genetic, D. Environmental Risk in Alzheimer's, C. Alzheimer's Disease Genetic
-
J.C. Lambert, C.A. Ibrahim-Verbaas, D. Harold, A.C. Naj, R. Sims, C. Bellenguez, G. Jun, A.L. Destefano, J.C. Bis, G.W. Beecham, B. Grenier-Boley, G. Russo, T.A. Thornton-Wells, N. Jones, A.V. Smith, V. Chouraki, C. Thomas, M.A. Ikram, D. Zelenika, B.N. Vardarajan, Y. Kamatani, C.F. Lin, A. Gerrish, H. Schmidt, B. Kunkle, M.L. Dunstan, A. Ruiz, M.T. Bihoreau, S.H. Choi, C. Reitz, F. Pasquier, P. Hollingworth, A. Ramirez, O. Hanon, A.L. Fitzpatrick, J.D. Buxbaum, D. Campion, P.K. Crane, C. Baldwin, T. Becker, V. Gudnason, C. Cruchaga, D. Craig, N. Amin, C. Berr, O.L. Lopez, P.L. De Jager, V. Deramecourt, J.A. Johnston, D. Evans, S. Lovestone, L. Letenneur, F.J. Moron, D.C. Rubinsztein, G. Eiriksdottir, K. Sleegers, A.M. Goate, N. Fievet, M.J. Huentelman, M. Gill, K. Brown, M.I. Kamboh, L. Keller, P. Barberger-Gateau, B. McGuinness, E.B. Larson, R. Green, A.J. Myers, C. Dufouil, S. Todd, D. Wallon, S. Love, E. Rogaeva, J. Gallacher, P. St George-Hyslop, J. Clarimon, A. Lleo, A. Bayer, D.W. Tsuang, L. Yu, M. Tsolaki, P. Bossu, G. Spalletta, P. Proitsi, J. Collinge, S. Sorbi, F. Sanchez-Garcia, N.C. Fox, J. Hardy, M.C. Naranjo, P. Bosco, R. Clarke, C. Brayne, D. Galimberti, M. Mancuso, F. Matthews, I. European Alzheimer's Disease, Genetic, D. Environmental Risk in Alzheimer's, C. Alzheimer's Disease Genetic, H. Cohorts for, E, Aging Research in Genomic, S. Moebus, P. Mecocci, M. Del Zompo, W. Maier, H. Hampel, A. Pilotto, M. Bullido, F. Panza, P. Caffarra, B. Nacmias, J.R. Gilbert, M. Mayhaus, L. Lannfelt, H. Hakonarson, S. Pichler, M.M. Carrasquillo, M. Ingelsson, D. Beekly, V. Alvarez, F. Zou, O. Valladares, S.G. Younkin, E. Coto, K.L. Hamilton-Nelson, W. Gu, C. Razquin, P. Pastor, I. Mateo, M.J. Owen, K.M. Faber, P.V. Jonsson, O. Combarros, M.C. O'Donovan, L.B. Cantwell, H. Soininen, D. Blacker, S. Mead, T.H. Mosley Jr., D.A. Bennett, T.B. Harris, L. Fratiglioni, C. Holmes, R.F. de Bruijn, P. Passmore, T.J. Montine, K. Bettens, J.I. Rotter, A. Brice, K. Morgan, T.M. Foroud, W.A. Kukull, D. Hannequin, J.F. Powell, M.A. Nalls, K. Ritchie, K.L. Lunetta, J.S. Kauwe, E. Boerwinkle, M. Riemenschneider, M. Boada, M. Hiltunen, E.R. Martin, R. Schmidt, D. Rujescu, L.S. Wang, J.F. Dartigues, R. Mayeux, C. Tzourio, A. Hofman, M.M. Nothen, C. Graff, B.M. Psaty, L. Jones, J.L. Haines, P.A. Holmans, M. Lathrop, M.A. Pericak-Vance, L.J. Launer, L.A. Farrer, C.M. van Duijn, C. Van Broeckhoven, V. Moskvina, S. Seshadri, J. Williams, G.D. Schellenberg, and P. Amouyel Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease Nat. Genet. 45 2013 1452 1458
-
(2013)
Nat. Genet.
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
Jun, G.7
Destefano, A.L.8
Bis, J.C.9
Beecham, G.W.10
Grenier-Boley, B.11
Russo, G.12
Thornton-Wells, T.A.13
Jones, N.14
Smith, A.V.15
Chouraki, V.16
Thomas, C.17
Ikram, M.A.18
Zelenika, D.19
Vardarajan, B.N.20
Kamatani, Y.21
Lin, C.F.22
Gerrish, A.23
Schmidt, H.24
Kunkle, B.25
Dunstan, M.L.26
Ruiz, A.27
Bihoreau, M.T.28
Choi, S.H.29
Reitz, C.30
Pasquier, F.31
Hollingworth, P.32
Ramirez, A.33
Hanon, O.34
Fitzpatrick, A.L.35
Buxbaum, J.D.36
Campion, D.37
Crane, P.K.38
Baldwin, C.39
Becker, T.40
Gudnason, V.41
Cruchaga, C.42
Craig, D.43
Amin, N.44
Berr, C.45
Lopez, O.L.46
De Jager, P.L.47
Deramecourt, V.48
Johnston, J.A.49
Evans, D.50
Lovestone, S.51
Letenneur, L.52
Moron, F.J.53
Rubinsztein, D.C.54
Eiriksdottir, G.55
Sleegers, K.56
Goate, A.M.57
Fievet, N.58
Huentelman, M.J.59
Gill, M.60
Brown, K.61
Kamboh, M.I.62
Keller, L.63
Barberger-Gateau, P.64
McGuinness, B.65
Larson, E.B.66
Green, R.67
Myers, A.J.68
Dufouil, C.69
Todd, S.70
Wallon, D.71
Love, S.72
Rogaeva, E.73
Gallacher, J.74
St George-Hyslop, P.75
Clarimon, J.76
Lleo, A.77
Bayer, A.78
Tsuang, D.W.79
Yu, L.80
Tsolaki, M.81
Bossu, P.82
Spalletta, G.83
Proitsi, P.84
Collinge, J.85
Sorbi, S.86
Sanchez-Garcia, F.87
Fox, N.C.88
Hardy, J.89
Naranjo, M.C.90
Bosco, P.91
Clarke, R.92
Brayne, C.93
Galimberti, D.94
Mancuso, M.95
Matthews, F.96
more..
-
82
-
-
25144514232
-
Somatic mitochondrial DNA mutations in single neurons and glia
-
I. Cantuti-Castelvetri, M.T. Lin, K. Zheng, C.E. Keller-McGandy, R.A. Betensky, D.R. Johns, M.F. Beal, D.G. Standaert, and D.K. Simon Somatic mitochondrial DNA mutations in single neurons and glia Neurobiol. Aging 26 2005 1343 1355
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 1343-1355
-
-
Cantuti-Castelvetri, I.1
Lin, M.T.2
Zheng, K.3
Keller-Mcgandy, C.E.4
Betensky, R.A.5
Johns, D.R.6
Beal, M.F.7
Standaert, D.G.8
Simon, D.K.9
-
83
-
-
84862742683
-
Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease
-
M.T. Lin, I. Cantuti-Castelvetri, K. Zheng, K.E. Jackson, Y.B. Tan, T. Arzberger, A.J. Lees, R.A. Betensky, M.F. Beal, and D.K. Simon Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease Ann. Neurol. 71 2012 850 854
-
(2012)
Ann. Neurol.
, vol.71
, pp. 850-854
-
-
Lin, M.T.1
Cantuti-Castelvetri, I.2
Zheng, K.3
Jackson, K.E.4
Tan, Y.B.5
Arzberger, T.6
Lees, A.J.7
Betensky, R.A.8
Beal, M.F.9
Simon, D.K.10
-
84
-
-
33644543761
-
Expanding insights of mitochondrial dysfunction in Parkinson's disease
-
P.M. Abou-Sleiman, M.M. Muqit, and N.W. Wood Expanding insights of mitochondrial dysfunction in Parkinson's disease Nat. Rev. Neurosci. 7 2006 207 219
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 207-219
-
-
Abou-Sleiman, P.M.1
Muqit, M.M.2
Wood, N.W.3
-
85
-
-
0032937059
-
Diagnostic criteria for Parkinson disease
-
D.J. Gelb, E. Oliver, and S. Gilman Diagnostic criteria for Parkinson disease Arch. Neurol. 56 1999 33 39
-
(1999)
Arch. Neurol.
, vol.56
, pp. 33-39
-
-
Gelb, D.J.1
Oliver, E.2
Gilman, S.3
-
86
-
-
0026514953
-
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases
-
A.J. Hughes, S.E. Daniel, L. Kilford, and A.J. Lees Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases J. Neurol. Neurosurg. Psychiatry 55 1992 181 184
-
(1992)
J. Neurol. Neurosurg. Psychiatry
, vol.55
, pp. 181-184
-
-
Hughes, A.J.1
Daniel, S.E.2
Kilford, L.3
Lees, A.J.4
-
87
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
M.G. Spillantini, M.L. Schmidt, V.M. Lee, J.Q. Trojanowski, R. Jakes, and M. Goedert Alpha-synuclein in Lewy bodies Nature 388 1997 839 840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
88
-
-
0342368772
-
Disease Genetics Study, D. European Consortium on Genetic Susceptibility in Parkinson's, Association between early-onset Parkinson's disease and mutations in the parkin gene
-
C.B. Lucking, A. Durr, V. Bonifati, J. Vaughan, G. De Michele, T. Gasser, B.S. Harhangi, G. Meco, P. Denefle, N.W. Wood, Y. Agid, A. Brice, and G. French Parkinson's. Disease Genetics Study, D. European Consortium on Genetic Susceptibility in Parkinson's, Association between early-onset Parkinson's disease and mutations in the parkin gene N. Engl. J. Med. 342 2000 1560 1567
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
89
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
E.M. Valente, P.M. Abou-Sleiman, V. Caputo, M.M. Muqit, K. Harvey, S. Gispert, Z. Ali, D. Del Turco, A.R. Bentivoglio, D.G. Healy, A. Albanese, R. Nussbaum, R. Gonzalez-Maldonado, T. Deller, S. Salvi, P. Cortelli, W.P. Gilks, D.S. Latchman, R.J. Harvey, B. Dallapiccola, G. Auburger, and N.W. Wood Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 304 2004 1158 1160
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
90
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
V. Bonifati, P. Rizzu, M.J. van Baren, O. Schaap, G.J. Breedveld, E. Krieger, M.C. Dekker, F. Squitieri, P. Ibanez, M. Joosse, J.W. van Dongen, N. Vanacore, J.C. van Swieten, A. Brice, G. Meco, C.M. van Duijn, B.A. Oostra, and P. Heutink Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism Science 299 2003 256 259
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
91
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
J.W. Langston, P. Ballard, J.W. Tetrud, and I. Irwin Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis Science 219 1983 979 980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
92
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
W.J. Nicklas, I. Vyas, and R.E. Heikkila Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine Life Sci. 36 1985 2503 2508
-
(1985)
Life Sci.
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
93
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease
-
A.H. Schapira, V.M. Mann, J.M. Cooper, D. Dexter, S.E. Daniel, P. Jenner, J.B. Clark, and C.D. Marsden Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease J. Neurochem. 55 1990 2142 2145
-
(1990)
J. Neurochem.
, vol.55
, pp. 2142-2145
-
-
Schapira, A.H.1
Mann, V.M.2
Cooper, J.M.3
Dexter, D.4
Daniel, S.E.5
Jenner, P.6
Clark, J.B.7
Marsden, C.D.8
-
94
-
-
0026484964
-
Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group
-
D. Krige, M.T. Carroll, J.M. Cooper, C.D. Marsden, and A.H. Schapira Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group Ann. Neurol. 32 1992 782 788
-
(1992)
Ann. Neurol.
, vol.32
, pp. 782-788
-
-
Krige, D.1
Carroll, M.T.2
Cooper, J.M.3
Marsden, C.D.4
Schapira, A.H.5
-
95
-
-
0028556287
-
Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease
-
C. Mytilineou, P. Werner, S. Molinari, A. Di Rocco, G. Cohen, and M.D. Yahr Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease J. Neural Transm. Park Dis. Dement. Sect. 8 1994 223 228
-
(1994)
J. Neural Transm. Park Dis. Dement. Sect.
, vol.8
, pp. 223-228
-
-
Mytilineou, C.1
Werner, P.2
Molinari, S.3
Di Rocco, A.4
Cohen, G.5
Yahr, M.D.6
-
96
-
-
0025831821
-
Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease
-
L.A. Bindoff, M.A. Birch-Machin, N.E. Cartlidge, W.D. Parker Jr., and D.M. Turnbull Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease J. Neurol. Sci. 104 1991 203 208
-
(1991)
J. Neurol. Sci.
, vol.104
, pp. 203-208
-
-
Bindoff, L.A.1
Birch-Machin, M.A.2
Cartlidge, N.E.3
Parker, W.D.4
Turnbull, D.M.5
-
98
-
-
0026718086
-
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
-
V.M. Mann, J.M. Cooper, D. Krige, S.E. Daniel, A.H. Schapira, and C.D. Marsden Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease Brain 115 Pt 2 1992 333 342
-
(1992)
Brain
, vol.115
, pp. 333-342
-
-
Mann, V.M.1
Cooper, J.M.2
Krige, D.3
Daniel, S.E.4
Schapira, A.H.5
Marsden, C.D.6
-
99
-
-
0027311153
-
No evidence for altered muscle mitochondrial function in Parkinson's disease
-
J.J. Anderson, D. Bravi, R. Ferrari, T.L. Davis, F. Baronti, T.N. Chase, and F. Dagani No evidence for altered muscle mitochondrial function in Parkinson's disease J. Neurol. Neurosurg. Psychiatry 56 1993 477 480
-
(1993)
J. Neurol. Neurosurg. Psychiatry
, vol.56
, pp. 477-480
-
-
Anderson, J.J.1
Bravi, D.2
Ferrari, R.3
Davis, T.L.4
Baronti, F.5
Chase, T.N.6
Dagani, F.7
-
100
-
-
0030945489
-
Respiratory chain enzyme activities in isolated mitochondria of lymphocytes from patients with Alzheimer's disease
-
J.A. Molina, F. de Bustos, F.J. Jimenez-Jimenez, J. Benito-Leon, T. Gasalla, M. Orti-Pareja, L. Vela, F. Bermejo, M.A. Martin, Y. Campos, and J. Arenas Respiratory chain enzyme activities in isolated mitochondria of lymphocytes from patients with Alzheimer's disease Neurology 48 1997 636 638
-
(1997)
Neurology
, vol.48
, pp. 636-638
-
-
Molina, J.A.1
De Bustos, F.2
Jimenez-Jimenez, F.J.3
Benito-Leon, J.4
Gasalla, T.5
Orti-Pareja, M.6
Vela, L.7
Bermejo, F.8
Martin, M.A.9
Campos, Y.10
Arenas, J.11
-
101
-
-
0005427216
-
Mitochondria and Parkinson's disease
-
N. Chesselet, M.-F. Totowa, Humana Press
-
R.H. Swerdlow Mitochondria and Parkinson's disease N. Chesselet, M.-F. Totowa, Molecular Mechanisms of Neurodegenerative Diseases 2000 Humana Press 233 270
-
(2000)
Molecular Mechanisms of Neurodegenerative Diseases
, pp. 233-270
-
-
Swerdlow, R.H.1
-
102
-
-
84857963075
-
Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence
-
R.H. Swerdlow Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence Antioxid. Redox Signal. 16 2012 950 964
-
(2012)
Antioxid. Redox Signal.
, vol.16
, pp. 950-964
-
-
Swerdlow, R.H.1
-
103
-
-
0029908226
-
Origin and functional consequences of the complex i defect in Parkinson's disease
-
R.H. Swerdlow, J.K. Parks, S.W. Miller, J.B. Tuttle, P.A. Trimmer, J.P. Sheehan, J.P. Bennett Jr., R.E. Davis, and W.D. Parker Jr. Origin and functional consequences of the complex I defect in Parkinson's disease Ann. Neurol. 40 1996 663 671
-
(1996)
Ann. Neurol.
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett, J.P.7
Davis, R.E.8
Parker, W.D.9
-
104
-
-
0034809341
-
Cytoplasmic transfer of platelet mtDNA from elderly patients with Parkinson's disease to mtDNA-less HeLa cells restores complete mitochondrial respiratory function
-
Y. Aomi, C.S. Chen, K. Nakada, S. Ito, K. Isobe, H. Murakami, S.Y. Kuno, M. Tawata, R. Matsuoka, H. Mizusawa, and J.I. Hayashi Cytoplasmic transfer of platelet mtDNA from elderly patients with Parkinson's disease to mtDNA-less HeLa cells restores complete mitochondrial respiratory function Biochem. Biophys. Res. Commun. 280 2001 265 273
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 265-273
-
-
Aomi, Y.1
Chen, C.S.2
Nakada, K.3
Ito, S.4
Isobe, K.5
Murakami, H.6
Kuno, S.Y.7
Tawata, M.8
Matsuoka, R.9
Mizusawa, H.10
Hayashi, J.I.11
-
105
-
-
84879484724
-
Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease
-
G. Hudson, M. Nalls, J.R. Evans, D.P. Breen, S. Winder-Rhodes, K.E. Morrison, H.R. Morris, C.H. Williams-Gray, R.A. Barker, A.B. Singleton, J. Hardy, N.E. Wood, D.J. Burn, and P.F. Chinnery Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease Neurology 80 2013 2042 2048
-
(2013)
Neurology
, vol.80
, pp. 2042-2048
-
-
Hudson, G.1
Nalls, M.2
Evans, J.R.3
Breen, D.P.4
Winder-Rhodes, S.5
Morrison, K.E.6
Morris, H.R.7
Williams-Gray, C.H.8
Barker, R.A.9
Singleton, A.B.10
Hardy, J.11
Wood, N.E.12
Burn, D.J.13
Chinnery, P.F.14
-
106
-
-
0036903298
-
Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy
-
V. Maximov, A. Martynenko, G. Hunsmann, and V. Tarantul Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy Med. Hypotheses 59 2002 670 673
-
(2002)
Med. Hypotheses
, vol.59
, pp. 670-673
-
-
Maximov, V.1
Martynenko, A.2
Hunsmann, G.3
Tarantul, V.4
-
107
-
-
0030294728
-
Cytochrome c oxidase defects of the human substantia nigra in normal aging
-
K. Itoh, S. Weis, P. Mehraein, and J. Muller-Hocker Cytochrome c oxidase defects of the human substantia nigra in normal aging Neurobiol. Aging 17 1996 843 848
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 843-848
-
-
Itoh, K.1
Weis, S.2
Mehraein, P.3
Muller-Hocker, J.4
-
108
-
-
84880954005
-
Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms
-
C. Perier, A. Bender, E. Garcia-Arumi, M.J. Melia, J. Bove, C. Laub, T. Klopstock, M. Elstner, R.B. Mounsey, P. Teismann, T. Prolla, A.L. Andreu, and M. Vila Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms Brain 136 2013 2369 2378
-
(2013)
Brain
, vol.136
, pp. 2369-2378
-
-
Perier, C.1
Bender, A.2
Garcia-Arumi, E.3
Melia, M.J.4
Bove, J.5
Laub, C.6
Klopstock, T.7
Elstner, M.8
Mounsey, R.B.9
Teismann, P.10
Prolla, T.11
Andreu, A.L.12
Vila, M.13
-
109
-
-
84858604461
-
Relationship between mitochondria and alpha-synuclein: A study of single substantia nigra neurons
-
A.K. Reeve, T.K. Park, E. Jaros, G.R. Campbell, N.Z. Lax, P.D. Hepplewhite, K.J. Krishnan, J.L. Elson, C.M. Morris, I.G. McKeith, and D.M. Turnbull Relationship between mitochondria and alpha-synuclein: a study of single substantia nigra neurons Arch. Neurol. 69 2012 385 393
-
(2012)
Arch. Neurol.
, vol.69
, pp. 385-393
-
-
Reeve, A.K.1
Park, T.K.2
Jaros, E.3
Campbell, G.R.4
Lax, N.Z.5
Hepplewhite, P.D.6
Krishnan, K.J.7
Elson, J.L.8
Morris, C.M.9
McKeith, I.G.10
Turnbull, D.M.11
-
110
-
-
84878920856
-
Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease
-
S.K. Muller, A. Bender, C. Laub, T. Hogen, F. Schlaudraff, B. Liss, T. Klopstock, and M. Elstner Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease Neurobiol. Aging 34 2013 2231 2233
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 2231-2233
-
-
Muller, S.K.1
Bender, A.2
Laub, C.3
Hogen, T.4
Schlaudraff, F.5
Liss, B.6
Klopstock, T.7
Elstner, M.8
-
111
-
-
0035943058
-
Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD
-
D.A. Cottrell, E.L. Blakely, M.A. Johnson, P.G. Ince, and D.M. Turnbull Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD Neurology 57 2001 260 264
-
(2001)
Neurology
, vol.57
, pp. 260-264
-
-
Cottrell, D.A.1
Blakely, E.L.2
Johnson, M.A.3
Ince, P.G.4
Turnbull, D.M.5
-
112
-
-
0026718966
-
Brain cytochrome oxidase in Alzheimer's disease
-
S.J. Kish, C. Bergeron, A. Rajput, S. Dozic, F. Mastrogiacomo, L.J. Chang, J.M. Wilson, L.M. DiStefano, and J.N. Nobrega Brain cytochrome oxidase in Alzheimer's disease J. Neurochem. 59 1992 776 779
-
(1992)
J. Neurochem.
, vol.59
, pp. 776-779
-
-
Kish, S.J.1
Bergeron, C.2
Rajput, A.3
Dozic, S.4
Mastrogiacomo, F.5
Chang, L.J.6
Wilson, J.M.7
DiStefano, L.M.8
Nobrega, J.N.9
-
113
-
-
0020758778
-
Positron emission tomographic studies of aging and Alzheimer disease
-
M.J. de Leon, S.H. Ferris, A.E. George, D.R. Christman, J.S. Fowler, C. Gentes, B. Reisberg, B. Gee, M. Emmerich, Y. Yonekura, J. Brodie, Kricheff, II, and A.P. Wolf Positron emission tomographic studies of aging and Alzheimer disease AJNR Am. J. Neuroradiol. 4 1983 568 571
-
(1983)
AJNR Am. J. Neuroradiol.
, vol.4
, pp. 568-571
-
-
De Leon, M.J.1
Ferris, S.H.2
George, A.E.3
Christman, D.R.4
Fowler, J.S.5
Gentes, C.6
Reisberg, B.7
Gee, B.8
Emmerich, M.9
Yonekura, Y.10
Brodie, J.11
Kricheff, I.I.12
Wolf, A.P.13
-
114
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
G.W. Small, L.M. Ercoli, D.H. Silverman, S.C. Huang, S. Komo, S.Y. Bookheimer, H. Lavretsky, K. Miller, P. Siddarth, N.L. Rasgon, J.C. Mazziotta, S. Saxena, H.M. Wu, M.S. Mega, J.L. Cummings, A.M. Saunders, M.A. Pericak-Vance, A.D. Roses, J.R. Barrio, and M.E. Phelps Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease Proc. Natl. Acad. Sci. U. S. A. 97 2000 6037 6042
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
Bookheimer, S.Y.6
Lavretsky, H.7
Miller, K.8
Siddarth, P.9
Rasgon, N.L.10
Mazziotta, J.C.11
Saxena, S.12
Wu, H.M.13
Mega, M.S.14
Cummings, J.L.15
Saunders, A.M.16
Pericak-Vance, M.A.17
Roses, A.D.18
Barrio, J.R.19
Phelps, M.E.20
more..
-
115
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
J.W. Lustbader, M. Cirilli, C. Lin, H.W. Xu, K. Takuma, N. Wang, C. Caspersen, X. Chen, S. Pollak, M. Chaney, F. Trinchese, S. Liu, F. Gunn-Moore, L.F. Lue, D.G. Walker, P. Kuppusamy, Z.L. Zewier, O. Arancio, D. Stern, S.S. Yan, and H. Wu ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease Science 304 2004 448 452
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.F.14
Walker, D.G.15
Kuppusamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.20
Wu, H.21
more..
-
117
-
-
0025024024
-
Cytochrome oxidase deficiency in Alzheimer's disease
-
W.D. Parker Jr., C.M. Filley, and J.K. Parks Cytochrome oxidase deficiency in Alzheimer's disease Neurology 40 1990 1302 1303
-
(1990)
Neurology
, vol.40
, pp. 1302-1303
-
-
Parker, W.D.1
Filley, C.M.2
Parks, J.K.3
-
118
-
-
84860770991
-
No consistent evidence for association between mtDNA variants and Alzheimer disease
-
G. Hudson, R. Sims, D. Harold, J. Chapman, P. Hollingworth, A. Gerrish, G. Russo, M. Hamshere, V. Moskvina, N. Jones, C. Thomas, A. Stretton, P.A. Holmans, M.C. O'Donovan, M.J. Owen, J. Williams, P.F. Chinnery, and G. Consortium No consistent evidence for association between mtDNA variants and Alzheimer disease Neurology 78 2012 1038 1042
-
(2012)
Neurology
, vol.78
, pp. 1038-1042
-
-
Hudson, G.1
Sims, R.2
Harold, D.3
Chapman, J.4
Hollingworth, P.5
Gerrish, A.6
Russo, G.7
Hamshere, M.8
Moskvina, V.9
Jones, N.10
Thomas, C.11
Stretton, A.12
Holmans, P.A.13
O'Donovan, M.C.14
Owen, M.J.15
Williams, J.16
Chinnery, P.F.17
Consortium, G.18
-
119
-
-
77957822416
-
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease
-
e12037
-
A. Santoro, V. Balbi, E. Balducci, C. Pirazzini, F. Rosini, F. Tavano, A. Achilli, P. Siviero, N. Minicuci, E. Bellavista, M. Mishto, S. Salvioli, F. Marchegiani, M. Cardelli, F. Olivieri, B. Nacmias, A.M. Chiamenti, L. Benussi, R. Ghidoni, G. Rose, C. Gabelli, G. Binetti, S. Sorbi, G. Crepaldi, G. Passarino, A. Torroni, and C. Franceschi Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease PLoS One 5 2010 e12037
-
(2010)
PLoS One
, vol.5
-
-
Santoro, A.1
Balbi, V.2
Balducci, E.3
Pirazzini, C.4
Rosini, F.5
Tavano, F.6
Achilli, A.7
Siviero, P.8
Minicuci, N.9
Bellavista, E.10
Mishto, M.11
Salvioli, S.12
Marchegiani, F.13
Cardelli, M.14
Olivieri, F.15
Nacmias, B.16
Chiamenti, A.M.17
Benussi, L.18
Ghidoni, R.19
Rose, G.20
Gabelli, C.21
Binetti, G.22
Sorbi, S.23
Crepaldi, G.24
Passarino, G.25
Torroni, A.26
Franceschi, C.27
more..
-
120
-
-
70049112960
-
Mitochondrial haplogroup H and Alzheimer's disease - Is there a connection?
-
A. Maruszak, J.A. Canter, M. Styczynska, C. Zekanowski, and M. Barcikowska Mitochondrial haplogroup H and Alzheimer's disease - is there a connection? Neurobiol. Aging 30 2009 1749 1755
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 1749-1755
-
-
Maruszak, A.1
Canter, J.A.2
Styczynska, M.3
Zekanowski, C.4
Barcikowska, M.5
-
121
-
-
0030016323
-
Increased risk of dementia in mothers of Alzheimer's disease cases: Evidence for maternal inheritance
-
S.D. Edland, J.M. Silverman, E.R. Peskind, D. Tsuang, E. Wijsman, and J.C. Morris Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal inheritance Neurology 47 1996 254 256
-
(1996)
Neurology
, vol.47
, pp. 254-256
-
-
Edland, S.D.1
Silverman, J.M.2
Peskind, E.R.3
Tsuang, D.4
Wijsman, E.5
Morris, J.C.6
-
122
-
-
0027200741
-
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients
-
J.M. Shoffner, M.D. Brown, A. Torroni, M.T. Lott, M.F. Cabell, S.S. Mirra, M.F. Beal, C.C. Yang, M. Gearing, R. Salvo, and et al. Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients Genomics 17 1993 171 184
-
(1993)
Genomics
, vol.17
, pp. 171-184
-
-
Shoffner, J.M.1
Brown, M.D.2
Torroni, A.3
Lott, M.T.4
Cabell, M.F.5
Mirra, S.S.6
Beal, M.F.7
Yang, C.C.8
Gearing, M.9
Salvo, R.10
-
123
-
-
0030066069
-
Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients
-
M.D. Brown, J.M. Shoffner, Y.L. Kim, A.S. Jun, B.H. Graham, M.F. Cabell, D.S. Gurley, and D.C. Wallace Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients Am. J. Med. Genet. 61 1996 283 289
-
(1996)
Am. J. Med. Genet.
, vol.61
, pp. 283-289
-
-
Brown, M.D.1
Shoffner, J.M.2
Kim, Y.L.3
Jun, A.S.4
Graham, B.H.5
Cabell, M.F.6
Gurley, D.S.7
Wallace, D.C.8
-
124
-
-
0030299996
-
The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years
-
C. Tysoe, D. Robinson, C. Brayne, T. Dening, E.S. Paykel, F.A. Huppert, and D.C. Rubinsztein The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years J. Med. Genet. 33 1996 1002 1006
-
(1996)
J. Med. Genet.
, vol.33
, pp. 1002-1006
-
-
Tysoe, C.1
Robinson, D.2
Brayne, C.3
Dening, T.4
Paykel, E.S.5
Huppert, F.A.6
Rubinsztein, D.C.7
-
125
-
-
0036048612
-
Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases
-
J.R. Garcia-Lozano, P. Mir, R. Alberca, I. Aguilera, E. Gil Neciga, O. Fernandez-Lopez, A. Cayuela, and A. Nunez-Roldan Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases Eur. Neurol. 48 2002 34 36
-
(2002)
Eur. Neurol.
, vol.48
, pp. 34-36
-
-
Garcia-Lozano, J.R.1
Mir, P.2
Alberca, R.3
Aguilera, I.4
Gil Neciga, E.5
Fernandez-Lopez, O.6
Cayuela, A.7
Nunez-Roldan, A.8
-
126
-
-
0027933135
-
Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
-
M. Corral-Debrinski, T. Horton, M.T. Lott, J.M. Shoffner, A.C. McKee, M.F. Beal, B.H. Graham, and D.C. Wallace Marked changes in mitochondrial DNA deletion levels in Alzheimer brains Genomics 23 1994 471 476
-
(1994)
Genomics
, vol.23
, pp. 471-476
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
McKee, A.C.5
Beal, M.F.6
Graham, B.H.7
Wallace, D.C.8
-
127
-
-
0034709595
-
The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain
-
S.W. Chang, D. Zhang, H.D. Chung, and H.P. Zassenhaus The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain Biochem. Biophys. Res. Commun. 273 2000 203 208
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 203-208
-
-
Chang, S.W.1
Zhang, D.2
Chung, H.D.3
Zassenhaus, H.P.4
-
128
-
-
1242292303
-
Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans
-
C. Mawrin, E. Kirches, G. Krause, R. Schneider-Stock, B. Bogerts, C.K. Vorwerk, and K. Dietzmann Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans Neurosci. Lett. 357 2004 111 114
-
(2004)
Neurosci. Lett.
, vol.357
, pp. 111-114
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
Schneider-Stock, R.4
Bogerts, B.5
Vorwerk, C.K.6
Dietzmann, K.7
-
129
-
-
3242668604
-
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
-
P.E. Coskun, M.F. Beal, and D.C. Wallace Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication Proc. Natl. Acad. Sci. U. S. A. 101 2004 10726 10731
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 10726-10731
-
-
Coskun, P.E.1
Beal, M.F.2
Wallace, D.C.3
-
131
-
-
84922480908
-
Mitochondrial DNA haplogroup D4b is a protective factor for ischemic stroke in Chinese Han population
-
D. Yang, Q. Wang, Y. Shi, Y. Fan, H.X. Zheng, G. Song, Q. Feng, H. Zheng, and Y. He Mitochondrial DNA haplogroup D4b is a protective factor for ischemic stroke in Chinese Han population Mol. Genet. Genomics 289 2014 1241 1246
-
(2014)
Mol. Genet. Genomics
, vol.289
, pp. 1241-1246
-
-
Yang, D.1
Wang, Q.2
Shi, Y.3
Fan, Y.4
Zheng, H.X.5
Song, G.6
Feng, Q.7
Zheng, H.8
He, Y.9
-
132
-
-
48649083598
-
Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
-
A. Rosa, B.V. Fonseca, T. Krug, H. Manso, L. Gouveia, I. Albergaria, G. Gaspar, M. Correia, M. Viana-Baptista, R.M. Simoes, A.N. Pinto, R. Taipa, C. Ferreira, J.R. Fontes, M.R. Silva, J.P. Gabriel, I. Matos, G. Lopes, J.M. Ferro, A.M. Vicente, and S.A. Oliveira Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients BMC Med. Genet. 9 2008 57
-
(2008)
BMC Med. Genet.
, vol.9
, pp. 57
-
-
Rosa, A.1
Fonseca, B.V.2
Krug, T.3
Manso, H.4
Gouveia, L.5
Albergaria, I.6
Gaspar, G.7
Correia, M.8
Viana-Baptista, M.9
Simoes, R.M.10
Pinto, A.N.11
Taipa, R.12
Ferreira, C.13
Fontes, J.R.14
Silva, M.R.15
Gabriel, J.P.16
Matos, I.17
Lopes, G.18
Ferro, J.M.19
Vicente, A.M.20
Oliveira, S.A.21
more..
-
133
-
-
33847671417
-
Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females
-
Y. Nishigaki, Y. Yamada, N. Fuku, H. Matsuo, T. Segawa, S. Watanabe, K. Kato, K. Yokoi, S. Yamaguchi, Y. Nozawa, and M. Tanaka Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females Mitochondrion 7 2007 72 79
-
(2007)
Mitochondrion
, vol.7
, pp. 72-79
-
-
Nishigaki, Y.1
Yamada, Y.2
Fuku, N.3
Matsuo, H.4
Segawa, T.5
Watanabe, S.6
Kato, K.7
Yokoi, K.8
Yamaguchi, S.9
Nozawa, Y.10
Tanaka, M.11
-
134
-
-
34547447707
-
Oxidative stress, AGE, and atherosclerosis
-
E. Schleicher, and U. Friess Oxidative stress, AGE, and atherosclerosis Kidney Int. Suppl. 2007 S17 S26
-
(2007)
Kidney Int. Suppl.
, pp. S17-S26
-
-
Schleicher, E.1
Friess, U.2
-
135
-
-
38349014270
-
Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence
-
M. Schleicher, B.R. Shepherd, Y. Suarez, C. Fernandez-Hernando, J. Yu, Y. Pan, L.M. Acevedo, G.S. Shadel, and W.C. Sessa Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence J. Cell Biol. 180 2008 101 112
-
(2008)
J. Cell Biol.
, vol.180
, pp. 101-112
-
-
Schleicher, M.1
Shepherd, B.R.2
Suarez, Y.3
Fernandez-Hernando, C.4
Yu, J.5
Pan, Y.6
Acevedo, L.M.7
Shadel, G.S.8
Sessa, W.C.9
-
136
-
-
1542300730
-
Frontotemporal dementia and mitochondrial DNA transitions
-
M. Grazina, F. Silva, I. Santana, B. Santiago, C. Mendes, M. Simoes, M. Oliveira, L. Cunha, and C. Oliveira Frontotemporal dementia and mitochondrial DNA transitions Neurobiol. Dis. 15 2004 306 311
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 306-311
-
-
Grazina, M.1
Silva, F.2
Santana, I.3
Santiago, B.4
Mendes, C.5
Simoes, M.6
Oliveira, M.7
Cunha, L.8
Oliveira, C.9
-
137
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
D.R. Rosen, T. Siddique, D. Patterson, D.A. Figlewicz, P. Sapp, A. Hentati, D. Donaldson, J. Goto, J.P. O'Regan, H.X. Deng, and et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Nature 362 1993 59 62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
138
-
-
0031915174
-
Cytochrome c oxidase subunit i microdeletion in a patient with motor neuron disease
-
G.P. Comi, A. Bordoni, S. Salani, L. Franceschina, M. Sciacco, A. Prelle, F. Fortunato, M. Zeviani, L. Napoli, N. Bresolin, M. Moggio, C.D. Ausenda, J.W. Taanman, and G. Scarlato Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease Ann. Neurol. 43 1998 110 116
-
(1998)
Ann. Neurol.
, vol.43
, pp. 110-116
-
-
Comi, G.P.1
Bordoni, A.2
Salani, S.3
Franceschina, L.4
Sciacco, M.5
Prelle, A.6
Fortunato, F.7
Zeviani, M.8
Napoli, L.9
Bresolin, N.10
Moggio, M.11
Ausenda, C.D.12
Taanman, J.W.13
Scarlato, G.14
-
139
-
-
84862326984
-
Mitochondrial genome large rearrangements in the skeletal muscle of a patient with PMA
-
S. Zoccolella, L. Artuso, R. Capozzo, A. Amati, F. Guerra, I. Simone, G. Logroscino, and V. Petruzzella Mitochondrial genome large rearrangements in the skeletal muscle of a patient with PMA Eur. J. Neurol. 19 2012 e63 e64
-
(2012)
Eur. J. Neurol.
, vol.19
, pp. e63-e64
-
-
Zoccolella, S.1
Artuso, L.2
Capozzo, R.3
Amati, A.4
Guerra, F.5
Simone, I.6
Logroscino, G.7
Petruzzella, V.8
-
140
-
-
84863954100
-
Clonal expansion of mitochondrial DNA deletions and the progression of multiple sclerosis
-
G.R. Campbell, and D.J. Mahad Clonal expansion of mitochondrial DNA deletions and the progression of multiple sclerosis CNS Neurol. Disord. Drug Targets 11 2012 589 597
-
(2012)
CNS Neurol. Disord. Drug Targets
, vol.11
, pp. 589-597
-
-
Campbell, G.R.1
Mahad, D.J.2
-
141
-
-
84879288527
-
The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons
-
A. Reeve, M. Meagher, N. Lax, E. Simcox, P. Hepplewhite, E. Jaros, and D. Turnbull The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons J. Neurosci. 33 2013 10790 10801
-
(2013)
J. Neurosci.
, vol.33
, pp. 10790-10801
-
-
Reeve, A.1
Meagher, M.2
Lax, N.3
Simcox, E.4
Hepplewhite, P.5
Jaros, E.6
Turnbull, D.7
-
142
-
-
34948862122
-
Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease
-
P.T. Luoma, J. Eerola, S. Ahola, A.H. Hakonen, O. Hellstrom, K.T. Kivisto, P.J. Tienari, and A. Suomalainen Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease Neurology 69 2007 1152 1159
-
(2007)
Neurology
, vol.69
, pp. 1152-1159
-
-
Luoma, P.T.1
Eerola, J.2
Ahola, S.3
Hakonen, A.H.4
Hellstrom, O.5
Kivisto, K.T.6
Tienari, P.J.7
Suomalainen, A.8
|