No evidence of association between frontotemporal dementia and major European mtDNA haplogroups

European Journal of Neurology

Volumn 15, Issue 9, 2008, Pages 1006-1008

  Rose, G ^a   Longo, T ^a   Maletta, R ^b   Passarino, G ^a   Bruni, A C ^b   De Benedictis, G ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b ASL 6   (Italy)

Author keywords

Frontotemporal dementia; mtDNA; Risk factors

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGE; AGED; ARTICLE; CASE CONTROL STUDY; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; ETHNICITY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DEMENTIA; DNA, MITOCHONDRIAL; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; ITALY; MALE; MIDDLE AGED;

EID: 49549089537     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2008.02222.x     Document Type: Article

References (8)

1. Le Ber I, van der Zee J, Hannequin D, et al. Progranulin null mutations in both sporadic and familial frontotemporal dementia. Human Mutation 2007 28 : 846 855.
2. Bernardi L, Maletta RG, Tomaino C, et al. The effects of APOE and tau gene variability on risk of frontotemporal dementia. Neurobiology of Aging 2006 27 : 702 709.
3. Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006 443 : 787 795.
4. Torroni A, Huoponen K, Francalacci P, et al. Classification of European mtDNAs from an analysis of three European populations. Genetics 1996 144 : 1835 1850.
5. Achilli A, Rengo C, Magri C, et al. The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool. American Journal of Human Genetics 2004 75 : 910 918.
6. Weir BS. Genetic Data Analysis II. Sunderland, MA : Sinauer Associates Inc., 1996 : 165 166.
7. NCI-NHGRI Working Group on Replication in Association Studies. Replicating genotype phenotype associations. Nature 2007 447 : 655 660.
8. Samuels DC, Carothers AD, Horton R, Chinnery PF. The power to detect disease associations with mitochondrial DNA haplogroups. American Journal of Human Genetics 2006 78 : 713 720.