-
1
-
-
0032733691
-
The role of oxidative stress in Alzheimer disease
-
Markesbery W. R. The role of oxidative stress in Alzheimer disease. Arch. Neurol. 56:1999;1449-1452.
-
(1999)
Arch. Neurol.
, vol.56
, pp. 1449-1452
-
-
Markesbery, W.R.1
-
2
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci P., MacGarvey U., Beal M. F. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36:1994;747-751.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
3
-
-
0028345763
-
Reactive oxygen species in tumorigenesis
-
Feig D. I., Reid T. M., Loeb L. A. Reactive oxygen species in tumorigenesis. Cancer Res. 54:1994;1890s-1894s.
-
(1994)
Cancer Res.
, vol.54
-
-
Feig, D.I.1
Reid, T.M.2
Loeb, L.A.3
-
4
-
-
0014690248
-
Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat
-
Gross N. J., Getz G. S., Rabinowitz M. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J. Biol. Chem. 244:1969;1552-1562.
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 1552-1562
-
-
Gross, N.J.1
Getz, G.S.2
Rabinowitz, M.3
-
5
-
-
0015370851
-
The apparent turnover of mitochondria, ribosomes and sRNA of the brain in young adult and aged rats
-
Menzies R. A., Gold P. H. The apparent turnover of mitochondria, ribosomes and sRNA of the brain in young adult and aged rats. J. Neurochem. 19:1972;1671-1683.
-
(1972)
J. Neurochem.
, vol.19
, pp. 1671-1683
-
-
Menzies, R.A.1
Gold, P.H.2
-
6
-
-
0033028516
-
Mitochondrial involvement in Alzheimer's disease
-
Bonilla E., Tanji K., Hirano M., Vu T. H., DiMauro S., Schon E. A. Mitochondrial involvement in Alzheimer's disease. Biochim. Biophys. Acta. 1410:1999;171-182.
-
(1999)
Biochim. Biophys. Acta
, vol.1410
, pp. 171-182
-
-
Bonilla, E.1
Tanji, K.2
Hirano, M.3
Vu, T.H.4
Dimauro, S.5
Schon, E.A.6
-
7
-
-
0030882784
-
Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions
-
Smith T. S., Bennett J. P. Jr. Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions. Brain Res. Mol. Brain Res. 765:1997;183-188.
-
(1997)
Brain Res. Mol. Brain Res.
, vol.765
, pp. 183-188
-
-
Smith, T.S.1
Bennett J.P., Jr.2
-
8
-
-
0026732706
-
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
-
Cortopassi G. A., Shibata D., Soong N. W., Arnheim N. A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc. Natl. Acad. Sci. USA. 89:1992;7370-7374.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7370-7374
-
-
Cortopassi, G.A.1
Shibata, D.2
Soong, N.W.3
Arnheim, N.4
-
9
-
-
0022414054
-
Diagnosis of Alzheimer's disease
-
Khachaturian Z. S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1985;1097-1105.
-
(1985)
Arch. Neurol.
, vol.42
, pp. 1097-1105
-
-
Khachaturian, Z.S.1
-
10
-
-
0028011999
-
An improved general method to generate internal standards for competitive PCR
-
Forster E. An improved general method to generate internal standards for competitive PCR. Biotechniques. 16:1994;18-20.
-
(1994)
Biotechniques
, vol.16
, pp. 18-20
-
-
Forster, E.1
-
11
-
-
0025646076
-
Mitochondrial gene mutation: The ageing process and degenerative diseases
-
Linnane A. W., Baumer A., Maxwell R. J., Preston H., Zhang C. F., Marzuki S. Mitochondrial gene mutation: The ageing process and degenerative diseases. Biochem. Int. 22:1990;1067-1076.
-
(1990)
Biochem. Int.
, vol.22
, pp. 1067-1076
-
-
Linnane, A.W.1
Baumer, A.2
Maxwell, R.J.3
Preston, H.4
Zhang, C.F.5
Marzuki, S.6
-
12
-
-
0026786405
-
Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control
-
Bouaboula M., Legoux P., Pessegue B., Delpech B., Dumont X., Piechaczyk M., Casellas P., Shire D. Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control. J. Biol. Chem. 267:1992;21830-21838.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 21830-21838
-
-
Bouaboula, M.1
Legoux, P.2
Pessegue, B.3
Delpech, B.4
Dumont, X.5
Piechaczyk, M.6
Casellas, P.7
Shire, D.8
-
13
-
-
0029101232
-
Human aging is associated with stochastic somatic mutations of mitochondrial DNA
-
Kadenbach B., Munscher C., Frank V., Muller-Hocker J., Napiwotzki J. Human aging is associated with stochastic somatic mutations of mitochondrial DNA. Mutat. Res. 338:1995;161-172.
-
(1995)
Mutat. Res.
, vol.338
, pp. 161-172
-
-
Kadenbach, B.1
Munscher, C.2
Frank, V.3
Muller-Hocker, J.4
Napiwotzki, J.5
-
14
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski M., Horton T., Lott M. T., Shoffner J. M., Beal M. F., Wallace D. C. Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age. Nat. Genet. 2:1992;324-329.
-
(1992)
Nat. Genet.
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
15
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
Soong N. W., Hinton D. R., Cortopassi G., Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat. Genet. 2:1992;318-323.
-
(1992)
Nat. Genet.
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
16
-
-
0027933135
-
Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
-
Corral-Debrinski M., Horton T., Lott M. T., Shoffner J. M., McKee A. C., Beal M. F., Graham B. H., Wallace D. C. Marked changes in mitochondrial DNA deletion levels in Alzheimer brains. Genomics. 23:1994;471-476.
-
(1994)
Genomics
, vol.23
, pp. 471-476
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
McKee, A.C.5
Beal, M.F.6
Graham, B.H.7
Wallace, D.C.8
-
17
-
-
0025113789
-
Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence
-
Ikebe S., Tanaka M., Ohno K., Sato W., Hattori K., Kondo T., Mizuno Y., Ozawa T. Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence. Biochem. Biophys. Res. Commun. 170:1990;1044-1048.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.170
, pp. 1044-1048
-
-
Ikebe, S.1
Tanaka, M.2
Ohno, K.3
Sato, W.4
Hattori, K.5
Kondo, T.6
Mizuno, Y.7
Ozawa, T.8
-
18
-
-
0026471872
-
Accumulation of deletions in human mitochondrial DNA during normal aging: Analysis by quantitative PCR
-
Simonetti S., Chen X., DiMauro S., Schon E. A. Accumulation of deletions in human mitochondrial DNA during normal aging: Analysis by quantitative PCR. Biochim. Biophys. Acta. 1180:1992;113-122.
-
(1992)
Biochim. Biophys. Acta
, vol.1180
, pp. 113-122
-
-
Simonetti, S.1
Chen, X.2
Dimauro, S.3
Schon, E.A.4
-
19
-
-
0026408619
-
Cytochrome oxidase deficiency in Alzheimer's disease
-
Parker W. D. Jr. Cytochrome oxidase deficiency in Alzheimer's disease. Ann. N.Y. Acad. Sci. 640:1991;59-64.
-
(1991)
Ann. N.Y. Acad. Sci.
, vol.640
, pp. 59-64
-
-
Parker W.D., Jr.1
-
20
-
-
0025734299
-
The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease
-
Blass J. P., Gibson G. E. The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease. Rev. Neurol. (Paris). 147:1991;513-525.
-
(1991)
Rev. Neurol. (Paris)
, vol.147
, pp. 513-525
-
-
Blass, J.P.1
Gibson, G.E.2
-
21
-
-
0343050763
-
Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors
-
Peterson C., Goldman J. E. Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors. Proc. Natl. Acad. Sci. USA. 83:1986;2758-2762.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 2758-2762
-
-
Peterson, C.1
Goldman, J.E.2
-
23
-
-
0028179578
-
Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease
-
Ito E., Oka K., Etcheberrigaray R., Nelson T. J., McPhie D. L., Tofel-Grehl B., Gibson G. E., Alkon D. L. Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA. 91:1994;534-538.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 534-538
-
-
Ito, E.1
Oka, K.2
Etcheberrigaray, R.3
Nelson, T.J.4
McPhie, D.L.5
Tofel-Grehl, B.6
Gibson, G.E.7
Alkon, D.L.8
-
24
-
-
0027220966
-
Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease
-
Etcheberrigaray R., Ito E., Oka K., Tofel-Grehl B., Gibson G. E., Alkon D. L. Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;8209-8213.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8209-8213
-
-
Etcheberrigaray, R.1
Ito, E.2
Oka, K.3
Tofel-Grehl, B.4
Gibson, G.E.5
Alkon, D.L.6
-
26
-
-
0026071738
-
Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes
-
Stoneking M., Hedgecock D., Higuchi R. G., Vigilant L., Erlich H. A. Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes. Am. J. Hum. Genet. 48:1991;370-382.
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 370-382
-
-
Stoneking, M.1
Hedgecock, D.2
Higuchi, R.G.3
Vigilant, L.4
Erlich, H.A.5
-
27
-
-
0032967445
-
Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients
-
Lezza A. M., Mecocci P., Cormio A., Beal M. F., Cherubini A., Cantatore P., Senin U., Gadaleta M. N. Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients. FASEB J. 13:1999;1083-1088.
-
(1999)
FASEB J.
, vol.13
, pp. 1083-1088
-
-
Lezza, A.M.1
Mecocci, P.2
Cormio, A.3
Beal, M.F.4
Cherubini, A.5
Cantatore, P.6
Senin, U.7
Gadaleta, M.N.8
-
28
-
-
0025981359
-
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
-
Shibutani S., Takeshita M., Grollman A. P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature. 349:1991;431-434.
-
(1991)
Nature
, vol.349
, pp. 431-434
-
-
Shibutani, S.1
Takeshita, M.2
Grollman, A.P.3
-
29
-
-
0030296713
-
Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease
-
Chandrasekaran K., Hatanpaa K., Brady D. R., Rapoport S. I. Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease. Exp. Neurol. 142:1996;80-88.
-
(1996)
Exp. Neurol.
, vol.142
, pp. 80-88
-
-
Chandrasekaran, K.1
Hatanpaa, K.2
Brady, D.R.3
Rapoport, S.I.4
-
30
-
-
0027215961
-
A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue
-
Blanchard B. J., Park T., Fripp W. J., Lerman L. S., Ingram V. M. A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue. Neuroreport. 4:1993;799-802.
-
(1993)
Neuroreport
, vol.4
, pp. 799-802
-
-
Blanchard, B.J.1
Park, T.2
Fripp, W.J.3
Lerman, L.S.4
Ingram, V.M.5
-
31
-
-
0029101854
-
Decreased cytochrome-c oxidase activity and lack of age-related accumulation of mitochondrial DNA deletions in the brains of schizophrenics
-
Cavelier L., Jazin E. E., Eriksson I., Prince J., Bave U., Oreland L., Gyllensten U. Decreased cytochrome-c oxidase activity and lack of age-related accumulation of mitochondrial DNA deletions in the brains of schizophrenics. Genomics. 29:1995;217-224.
-
(1995)
Genomics
, vol.29
, pp. 217-224
-
-
Cavelier, L.1
Jazin, E.E.2
Eriksson, I.3
Prince, J.4
Bave, U.5
Oreland, L.6
Gyllensten, U.7
-
32
-
-
0025276996
-
Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease
-
Shoubridge E. A., Karpati G., Hastings K. E. Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease. Cell. 62:1990;43-49.
-
(1990)
Cell
, vol.62
, pp. 43-49
-
-
Shoubridge, E.A.1
Karpati, G.2
Hastings, K.E.3
-
33
-
-
0032030309
-
Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing
-
Liu V. W., Zhang C., Nagley P. Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing. Nucleic Acids Res. 26:1998;1268-1275.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1268-1275
-
-
Liu, V.W.1
Zhang, C.2
Nagley, P.3
-
34
-
-
0029741431
-
Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging
-
Pallotti F., Chen X., Bonilla E., Schon E. A. Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging. Am. J. Hum. Genet. 59:1996;591-602.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 591-602
-
-
Pallotti, F.1
Chen, X.2
Bonilla, E.3
Schon, E.A.4
|