Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria

Molecular and Cellular Biology

Volumn 20, Issue 3, 2000, Pages 805-815

  Bai, Yidong ^a   Shakeley, Rebecca M ^a   Attardi, Giuseppe ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME SUBUNIT; GENE EXPRESSION; GENETIC TRANSCRIPTION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; NONSENSE MUTATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TRANSLATION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE, TRANSFORMED; CHROMOSOME MAPPING; CODON, TERMINATOR; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KINETICS; L CELLS (CELL LINE); MACROMOLECULAR SUBSTANCES; MICE; MITOCHONDRIA; MUTATION, MISSENSE; NADH DEHYDROGENASE; OXYGEN CONSUMPTION; POINT MUTATION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0033971346     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.3.805-815.2000     Document Type: Article

References (53)

1. Ammini, C. V., and W. W. Hauswirth. 1999. Mitochondrial gene expression is regulated at the level of transcription during early embryogenesis of Xenopus laevis. J. Biol. Chem. 274:6265-6271.
2. Attardi, G. 1985. Animal mitochondrial DNA: an extreme example of genetic economy. Int. Rev. Cytol. 93:93-145.
3. Attardi, G., and G. Schatz. 1988. Biogenesis of mitochondria. Annu. Rev. Cell Biol. 4:289-333.
4. Attardi, G., A. Chomyn, and P. Loguercio. 1989. Evidence for translational control of mitochondrial gene expression in rat muscle and brain synaptosome mitochondria, p. 55-64. In G. Benzi (ed.), Advances in myochemistry, vol. 2. John Libbey Eurotext, Ltd., London, England.
5. Bai, Y. D., and G. Attardi. 1998. The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme. EMBO J. 17: 4848-4858.
6. + splice site choice in vivo by ASF/SF2 and hnRNP Al. Nucleic Acids Res. 27:1126-1134.
7. Bertram, J. S., and P. Janik. 1980. Establishment of a cloned line of Lewis lung carcinoma cells adapted to cell culture. Cancer Lett. 11:63-73.
8. Bibb, M. J., R. A. Van Etten, C. T. Wright, M. W., Walberg, and D. A. Clayton. 1981. Sequence and gene organization of mouse mitochondrial DNA. Cell 26:167-180.
9. Cantatore, P., P. L. Polosa, F. Fracasso, Z. Flagella, and M. N. Gadalenta. 1986. Quantitation of mitochondrial RNA species during rat liver development: the concentration of cytochrome oxidase subunit I (CO1) messenger RNA increases at birth. Cell Differ. 19:125-132.
10. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
11. Chomyn, A., P. Mariottini, M. W. J. Cleeter, C. I. Ragan, A. Matsuno-Yagi, Y. Hatefi, R. F. Doolittle, and G. Attardi. 1985. Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory chain NADH dehydrogenase. Nature 314:592-597.
12. Chomyn, A. 1996. In vivo labeling and analysis of human mitochondrial translation products. Methods Enzymol. 264:197-211.
13. Desjardins, P., E. Frost, and R. Morais. 1985. Ethidium bromide induced loss of mitochondrial DNA from primary chicken embryo fibroblasts. Mol. Cell. Biol. 5:1163-1169.
14. England, J., P. Constantino, and G. Attardi. 1978. Mitochondrial RNA and protein synthesis in enucleated African green monkey cells. J. Mol. Biol. 119:455-462.
15. Lys and premature translation termination. Nat. Genet. 10:47-55.
16. Enriquez, J. A., P. Fernandez-Silva, N. Garrido-Perez, and J. Montoya. 1999. Direct regulation of mitochondrial RNA synthesis by thyroid hormone. Mol. Cell. Biol. 19:657-670.
17. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
18. Fox, T. D. 1996. Translational control of endogenous and recorded nuclear genes in yeast mitochondria: regulation and membrane targeting. Experientia 52:1130-1135.
19. Freshney, R. I. 1994. Culture of animal cells. Wiley-Liss, Inc., New York, N.Y.
20. Galante, Y. M., and Y. Hatefi. 1979. Purification and molecular and enzymatic properties of mitochondrial NADH dehydrogenase. Arch. Biochem. Biophys. 192:559-568.
21. Gelfand, R., and G. Attardi. 1981. Synthesis and turnover of mitochondrial ribonucleic acid in HeLa cells: the mature ribosomal and messenger ribonucleic acid species are metabolically unstable. Mol. Cell. Biol. 1:497-511.
22. Ser(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression. Mol. Cell. Biol. 18:5868-5879.
23. Hayashi, J.-I., S. Ohta, A. Kikuchi, M. Takemitsu, Y.-I. Goto, and I. Nonaka. 1991. Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc. Natl. Acad. Sci. USA 88:10614-10618.
24. Hofhaus, G., and G. Attardi. 1993. Lack of assembly of mitochondrial DNA-encoded submits of respiratory NADH dehydrogenase and loss of enzyme activity in a human cell mutant lacking the mitochondrial ND4 gene product. EMBO J. 12:3043-3048.
25. Hofhaus, G., and G. Attardi. 1995. Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase. Mol. Cell. Biol. 15:964-974.
26. Hofhaus, G., D. R. Johns, O. Hurko, G. Attardi, and A. Chomyn. 1996. Respiration and growth defects in transmitochondrial cell lines carrying the 11778 mutation associated with Leber's hereditary optic neuropathy. J. Biol. Chem. 271:13155-13161.
27. Hofhaus, G., R. M. Shakeley, and G. Attardi. 1996. Use of polarography to detect respiration defects in cell cultures. Methods Enzymol. 264:476-483.
28. Jun, A. S., I. A. Trounce, M. D. Brown, J. M. Shoffner, and D. C. Wallace. 1996. Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia. Mol. Cell. Biol. 16:771-777.
29. King, M. P., and G. Attardi. 1989. Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 246:500-503.
30. King, M. P. 1996. Use of ethidium bromide to manipulate ratio of mutant and wild-type mitochondrial DNA in cultured cells. Methods Enzymol. 264: 339-344.
31. Kuznetsov, A. V., J. F. Clark, K. Winkler, and W. S. Kunz. 1996. Increase of flux control of cytochrome c oxidase in copper-deficient mottled brindled mice. J. Biol. Chem. 271:283-288.
32. Lansman, R. A., and D. A. Clayton. 1975. Mitochondrial protein synthesis in mouse L cells: effect of selective nicking of mitochondrial DNA. J. Mol. Biol. 99:777-793.
33. Larsson, N. G., E. Holme, B. Kristiansson, A. Oldfors, and M. Tulinius. 1990. Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome. Pediatr. Res. 28:131-136.
34. Litllefield, J. W. 1963. The inosinic acid pyrophosphorylase activity of mouse fibroblasts partially resistant to 8-azaguanine. Proc. Natl. Acad. Sci. USA 50:568-576.
35. Loguercio Polosa, P., and G. Attardi. 1991. Distinctive pattern and translational control of mitochondrial protein synthesis in rat brain synaptic endings. J. Biol. Chem. 266:10011-10017.
36. Majander, A., M. Finel, M. L. Savontaus, E. Nikoskelainen, and M. Wikstrom. 1996. Catalytic activity of complex 1 in cell lines that possess replacement mutations in the ND genes in Leber's hereditary optic neuropathy. Eur. J. Biochem. 239:201-207.
37. Maquat, L. E. 1988. When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. RNA 1:453-465.
38. Mariottini, P., A. Chomyn, M. Riley, B. Cottrell, R. F. Doolitlle, and G. Attardi. 1986. Identification of the polypeptides encoded in the unassigned reading frame-2, frame-4, frame-4L and frame-5 of human mitochondrial DNA. Proc. Natl. Acad. Sci. USA 83:1563-1567.
39. Mariottini, P., and A. Chomyn. 1996. Immunoprecipitation of human NADH:ubiquinone oxidoreductase and cytochrome c oxidase with single subunit-specific antibodies. Methods Enzymol. 260:202-210.
40. Mitchell, C. H., and G. Attardi. 1978. Cytoplasmic transfer of chloramphenicol resistance in a human cell line. Somat. Cell Genet. 4:737-744.
41. Leu(UUR) mutation in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS): genetic, biochemical, and morphological correlations in skeletal muscle. Am. J. Hum. Genet. 50:934-949.
42. Ostronoff, L. K., J. M. Izquierdo, and J. M. Cuezva. 1995. mt-mRNA stability regulates the expression of the mitochondrial genome during liver development. Biochem. Biophys. Res. Commun. 217:1094-1098.
43. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
44. Storrie, B., and G. Attardi. 1972. Expression of the mitochondrial genome in HeLa cells. XIII. Effect of selective inhibition of cytoplasmic or mitochondrial protein synthesis on mitochondrial nucleic acid synthesis. J. Mol. Biol. 71:177-199.
45. Villani, G., and G. Attardi. 1997. In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells. Proc. Natl. Acad. Sci. USA 94:1165-1171.
46. Villani, G., M. Greco, S. Papa, and G. Attardi. 1998. Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types. J. Biol. Chem. 273:31829-31836.
47. Wallace, D. C., J. M. Shoffner, I. Trounce, M. D. Brown, S. W. Ballinger, M. Corral-Debrinski, T. Horton, A. S. Jun, and M. T. Lott. 1995. Mitochondrial DNA mutations in human degenerative diseases and aging. Biochem. Biophys. Acta 127:141-151.
48. Weiss, H., T. Friedrich, G. Hofhaus, and D. Preis. 1991. The respiratory chain NADH dehydrogenase (complex I) of mitochondria. Eur. J. Biochem. 197:563-576.
49. Williams, R. S. 1986. Mitochondrial gene expression in mammalian striated muscle: evidence that variation in gene dosage is the major regulatory event. J. Biol. Chem. 261:12390-12394.
50. Williams, R. S., S. Salmons, E. A. Newsholme, R. E. Kaufman, and J. Mellor. 1986. Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. J. Biol. Chem. 261:376-380.
51. Wiseman, A., and G. Attardi. 1978. Reversible ten-fold reduction in mitochondrial DNA content of human cells treated with ethidium bromide. Mol. Gen. Genet. 167:51-63.
52. Yoneda, M., A. Chomyn, A. Martinuzzi, O. Hurko, and G. Attardi. 1992. Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc. Natl. Acad. Sci. USA 89:11164-11168.
53. Yoneda, M., T. Miyatake, and G. Attardi. 1994. Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles. Mol. Cell. Biol. 14:2699-2712.