Softer zwitterionic nanogels for longer circulation and lower splenic accumulation

ACS Nano

Volumn 6, Issue 8, 2012, Pages 6681-6686

  Zhang, Lei ^a   Cao, Zhiqiang ^a   Li, Yuting ^a   Ella Menye, Jean Rene ^a   Bai, Tao ^a   Jiang, Shaoyi ^a  

^a University of Washington   (United States)

Author keywords

drug delivery; long circulating nanoparticles; nanoparticle stiffness; splenic filtration; zwitterionic

Indexed keywords

CROSS-LINKING DENSITY; IN-VIVO; NANOGELS; VARYING STIFFNESS; ZWITTERIONIC;

DRUG DELIVERY; NANOPARTICLES; STIFFNESS;

NANOSTRUCTURED MATERIALS;

BIOMATERIAL; NANOPARTICLE;

ANIMAL; ARTICLE; BLOOD ANALYSIS; CHEMISTRY; CONFORMATION; HARDNESS; HYDROGEL; MATERIALS TESTING; PARTICLE SIZE; RAT; SPLEEN; STATIC ELECTRICITY; SURFACE PROPERTY; SYNTHESIS; ULTRASTRUCTURE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BLOOD CHEMICAL ANALYSIS; HARDNESS; HYDROGELS; MATERIALS TESTING; MOLECULAR CONFORMATION; NANOPARTICLES; PARTICLE SIZE; RATS; SPLEEN; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 84865600098     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn301159a     Document Type: Article

References (27)

1. Moghimi, S. M.; Hunter, A. C.; Murray, J. C. Long-Circulating and Target-Specific Nanoparticles: Theory to Practice Pharmacol. Rev. 2001, 53, 283-318
2. Gu, F.; Zhang, L.; Teply, B. A.; Mann, N.; Wang, A.; Radovic-Moreno, A. F.; Langer, R.; Farokhzad, O. C. Precise Engineering of Targeted Nanoparticles by Using Self-Assembled Biointegrated Block Copolymers Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 2586-2591
3. Zhang, L.; Yu, F. Q.; Cole, A. J.; Chertok, B.; David, A. E.; Wang, J. K.; Yang, V. C. Gum Arabic-Coated Magnetic Nanoparticles for Potential Application in Simultaneous Magnetic Targeting and Tumor Imaging AAPS J. 2009, 11, 693-699
4. van Schooneveld, M. M.; Vucic, E.; Koole, R.; Zhou, Y.; Stocks, J.; Cormode, D. P.; Tang, C. Y.; Gordon, R. E.; Nicolay, K.; Meijerink, A. et al. Improved Biocompatibility and Pharmacokinetics of Silica Nanoparticles by Means of a Lipid Coating: A Multimodality Investigation Nano Lett. 2008, 8, 2517-2525
5. Peer, D.; Karp, J. M.; Hong, S.; Farokhzad, O. C.; Margalit, R.; Langer, R. Nanocarriers as an Emerging Platform for Cancer Therapy Nat. Nanotechnol. 2007, 2, 751-760
6. Zhang, L.; Gu, F. X.; Chan, J. M.; Wang, A. Z.; Langer, R. S.; Farokhzad, O. C. Nanoparticles in Medicine: Therapeutic Applications and Developments Clin. Pharmacol. Ther. 2008, 83, 761-769
7. Mornet, S.; Vasseur, S.; Grasset, F.; Duguet, E. Magnetic Nanoparticle Design for Medical Diagnosis and Therapy J. Mater. Chem. 2004, 14, 2161-2175
8. Corot, C.; Robert, P.; Idee, J. M.; Port, M. Recent Advances in Iron Oxide Nanocrystal Technology for Medical Imaging Adv. Drug Delivery Rev. 2006, 58, 1471-1504
9. Mebius, R. E.; Kraal, G. Structure and Function of the Spleen Nat. Rev. Immunol. 2005, 5, 606-616
10. Perrault, S. D.; Walkey, C.; Jennings, T.; Fischer, H. C.; Chan, W. C. W. Mediating Tumor Targeting Efficiency of Nanoparticles through Design Nano Lett. 2009, 9, 1909-1915
11. Moghimi, S. M.; Porter, C. J.; Muir, I. S.; Illum, L.; Davis, S. S. Non-phagocytic Uptake of Intravenously Injected Microspheres in Rat Spleen: Influence of Particle Size and Hydrophilic Coating Biochem. Biophys. Res. Commun. 1991, 177, 861-866
12. Zhang, G. D.; Yang, Z.; Lu, W.; Zhang, R.; Huang, Q.; Tian, M.; Li, L.; Liang, D.; Li, C. Influence of Anchoring Ligands and Particle Size on the Colloidal Stability and In Vivo Biodistribution of Polyethylene Glycol-Coated Gold Nanoparticles in Tumor-Xenografted Mice Biomaterials 2009, 30, 1928-1936
13. Choi, H. S.; Liu, W.; Misra, P.; Tanaka, E.; Zimmer, J. P.; Ipe, B. I.; Bawendi, M. G.; Frangioni, J. V. Renal Clearance of Quantum Dots Nat. Biotechnol. 2007, 25, 1165-1170
14. Geng, Y.; Dalhaimer, P.; Cai, S. S.; Tsai, R.; Tewari, M.; Minko, T.; Discher, D. E. Shape Effects of Filaments versus Spherical Particles in Flow and Drug Delivery Nat. Nanotechnol. 2007, 2, 249-255
15. Park, J. H.; von Maltzahn, G.; Zhang, L. L.; Derfus, A. M.; Simberg, D.; Harris, T. J.; Ruoslahti, E.; Bhatia, S. N.; Sailor, M. J. Systematic Surface Engineering of Magnetic Nanoworms for In Vivo Tumor Targeting Small 2009, 5, 694-700
16. Merkel, T. J.; Jones, S. W.; Herlihy, K. P.; Kersey, F. R.; Shields, A. R.; Napier, M.; Luft, J. C.; Wu, H.; Zamboni, W. C.; Wang, A. Z. et al. Using Mechanobiological Mimicry of Red Blood Cells To Extend Circulation Times of Hydrogel Microparticles Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 586-591
17. Mitragotri, S.; Lahann, J. Physical Approaches to Biomaterial Design Nat. Mater. 2009, 8, 15-23
18. Jiang, S. Y.; Cao, Z. Q. Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications Adv. Mater. 2010, 22, 920-932
19. Yang, W.; Zhang, L.; Wang, S. L.; White, A. D.; Jiang, S. Y. Functionalizable and Ultra Stable Nanoparticles Coated with Zwitterionic Poly(carboxybetaine) in Undiluted Blood Serum Biomaterials 2009, 30, 5617-5621
20. Zhang, L.; Xue, H.; Gao, C. L.; Carr, L.; Wang, J. N.; Chu, B. C.; Jiang, S. Y. Imaging and Cell Targeting Characteristics of Magnetic Nanoparticles Modified by a Functionalizable Zwitterionic Polymer with Adhesive 3,4-Dihydroxyphenyl- l -Alanine Linkages Biomaterials 2010, 31, 6582-6588
21. Carr, L. R.; Zhou, Y. B.; Krause, J. E.; Xue, H.; Jiang, S. Y. Uniform Zwitterionic Polymer Hydrogels with a Nonfouling and Functionalizable Crosslinker Using Photopolymerization Biomaterials 2011, 32, 6893-6899
22. Zhang, L.; Xue, H.; Cao, Z.; Keefe, A.; Wang, J.; Jiang, S. Multifunctional and Degradable Zwitterionic Nanogels for Targeted Delivery, Enhanced MR Imaging, Reduction-Sensitive Drug Release, and Renal Clearance Biomaterials 2011, 32, 4604-4608
23. Cai, Q.; Kim, S. H.; Choi, K. S.; Kim, S. Y.; Byun, S. J.; Kim, K. W.; Park, S. H.; Juhng, S. K.; Yoon, K. Colloidal Gold Nanoparticles as a Blood-Pool Contrast Agent for X-ray Computed Tomography in Mice Invest. Radiol. 2007, 42, 797-806
24. Kim, D.; Park, S.; Lee, J. H.; Jeong, Y. Y.; Jon, S. Antibiofouling Polymer-Coated Gold Nanoparticles as a Contrast Agent for In Vivo X-ray Computed Tomography Imaging J. Am. Chem. Soc. 2007, 129, 7661-7665
25. Cheng, J. J.; Teply, B. A.; Sherifi, I.; Sung, J.; Luther, G.; Gu, F. X.; Levy-Nissenbaum, E.; Radovic-Moreno, A. F.; Langer, R. et al. Formulation of Functionalized PLGA-PEG Nanoparticles for In Vivo Targeted Drug Delivery Biomaterials 2007, 28, 869-876
26. Mohanraj, V. J.; Chen, Y. Nanoparticles-A Review Trop. J. Pharm. Res. 2006, 5, 561-573
27. Redhead, H. M.; Davis, S. S.; Illum, L. Drug Delivery in Poly(lactide- co -glycolide) Nanoparticles Surface Modified with Poloxamer 407 and Poloxamine 908: In Vitro Characterisation and In Vivo Evaluation J. Controlled Release 2001, 70, 353-363