SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 16, 2015, Pages 5087-5097

Perspective: Challenges and opportunities in TB drug discovery from phenotypic screening

(2) Manjunatha, Ujjini H a Smith, Paul W a

a NOVARTIS INSTITUTE FOR TROPICAL DISEASES (Singapore)

Author keywords

Drug discovery; Mycobacterium; New chemical entities; Phenotypic screening; Tuberculosis

Indexed keywords

4 HYDROXYPYRIDONE DERIVATIVE; CARRIER PROTEINS AND BINDING PROTEINS; IMIDAZOLE DERIVATIVE; IMIDAZOPYRIDINE DERIVATIVE; INDOLCARBOXAMIDE; IPA 4; NITD 192; NITD 304; NITD 501; NITD 529; NITD 916; PROTEIN DRPE1; PROTEIN MMPL3; PROTEIN QCRB; PYRAZOLOPYRIMIDINE; PYRIMIDINYLIMIDAZOLE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; BACTERIAL PROTEIN;

ANTIBACTERIAL ACTIVITY; BACTERIAL GROWTH; DRUG EFFICACY; DRUG POTENCY; DRUG RESEARCH; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; LIPOPHILICITY; MEDICINAL CHEMISTRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACODYNAMICS; PROCESS OPTIMIZATION; PROTEIN TARGETING; REVIEW; TUBERCULOSIS; ANIMAL; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULARLY TARGETED THERAPY; MYCOBACTERIUM TUBERCULOSIS; PROCEDURES;

MYCOBACTERIUM;

ANIMALS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MOLECULAR TARGETED THERAPY; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

EID: 84938972601 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.12.031 Document Type: Article

Times cited : (90)

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