-
1
-
-
85016921782
-
Dietary glucosinolates sulforaphane, phenethyl isothiocyanate, indole-3-carbinol/3,3′-diindolylmethane: antioxidative stress/inflammation, Nrf2, epigenetics/epigenomics and in vivo cancer chemopreventive efficacy
-
F. Fuentes, X. Paredes-Gonzalez, and A.-N.T. Kong Dietary glucosinolates sulforaphane, phenethyl isothiocyanate, indole-3-carbinol/3,3′-diindolylmethane: antioxidative stress/inflammation, Nrf2, epigenetics/epigenomics and in vivo cancer chemopreventive efficacy Curr. Pharmacol. Rep. 1 2015 179 196
-
(2015)
Curr. Pharmacol. Rep.
, vol.1
, pp. 179-196
-
-
Fuentes, F.1
Paredes-Gonzalez, X.2
Kong, A.-N.T.3
-
2
-
-
84901244406
-
An evaluation of sulforaphane as a potential agent for disease prevention
-
N.S. Alrawaiq, and A. Abdullah An evaluation of sulforaphane as a potential agent for disease prevention Res. J. Pharm. Biol. Chem. Sci. 5 2014 1335 1349
-
(2014)
Res. J. Pharm. Biol. Chem. Sci.
, vol.5
, pp. 1335-1349
-
-
Alrawaiq, N.S.1
Abdullah, A.2
-
3
-
-
84858153162
-
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity
-
V. Calabrese, C. Cornelius, A.T. Dinkova-Kostova, I. Iavicoli, R. Di Paola, A. Koverech, and et al. Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity Biochim. Biophys. Acta Mol. Basis Dis. 2012 1822 753 783
-
(1822)
Biochim. Biophys. Acta Mol. Basis Dis.
, vol.2012
, pp. 753-783
-
-
Calabrese, V.1
Cornelius, C.2
Dinkova-Kostova, A.T.3
Iavicoli, I.4
Di Paola, R.5
Koverech, A.6
-
4
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure
-
Y. Zhang, P. Talalay, C.G. Cho, and G.H. Posner A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure Proc. Natl. Acad. Sci. U. S. A. 89 1992 2399 2403
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
5
-
-
84875157012
-
Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin
-
I.M.A. Ernst, K. Palani, T. Esatbeyoglu, K. Schwarz, and G. Rimbach Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin Pharmacol. Res. 70 2013 155 162
-
(2013)
Pharmacol. Res.
, vol.70
, pp. 155-162
-
-
Ernst, I.M.A.1
Palani, K.2
Esatbeyoglu, T.3
Schwarz, K.4
Rimbach, G.5
-
6
-
-
0035808553
-
The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
-
J.W. Fahey, A.T. Zalcmann, and P. Talalay The chemical diversity and distribution of glucosinolates and isothiocyanates among plants Phytochemistry 56 2001 5 51
-
(2001)
Phytochemistry
, vol.56
, pp. 5-51
-
-
Fahey, J.W.1
Zalcmann, A.T.2
Talalay, P.3
-
7
-
-
84859161954
-
Glucosinolate structures in evolution
-
N. Agerbirk, and C.E. Olsen Glucosinolate structures in evolution Phytochemistry 77 2012 16 45
-
(2012)
Phytochemistry
, vol.77
, pp. 16-45
-
-
Agerbirk, N.1
Olsen, C.E.2
-
8
-
-
84903286823
-
Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds
-
G.R. De Nicola, P. Rollin, E. Mazzon, and R. Iori Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds Molecules 19 2014 6975 6986
-
(2014)
Molecules
, vol.19
, pp. 6975-6986
-
-
De Nicola, G.R.1
Rollin, P.2
Mazzon, E.3
Iori, R.4
-
9
-
-
55049121677
-
Determination of the absolute configuration of the glucosinolate methyl sulfoxide group reveals a stereospecific biosynthesis of the side chain
-
F. Vergara, M. Wenzler, B.G. Hansen, D.J. Kliebenstein, B.A. Halkier, J. Gershenzon, and et al. Determination of the absolute configuration of the glucosinolate methyl sulfoxide group reveals a stereospecific biosynthesis of the side chain Phytochemistry 69 2008 2737 2742
-
(2008)
Phytochemistry
, vol.69
, pp. 2737-2742
-
-
Vergara, F.1
Wenzler, M.2
Hansen, B.G.3
Kliebenstein, D.J.4
Halkier, B.A.5
Gershenzon, J.6
-
10
-
-
79955416779
-
The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer
-
A.F. Abdull Razis, R. Iori, and C. Ioannides The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer Int. J. Cancer 128 2011 2775 2782
-
(2011)
Int. J. Cancer
, vol.128
, pp. 2775-2782
-
-
Abdull Razis, A.F.1
Iori, R.2
Ioannides, C.3
-
11
-
-
79953706274
-
Potential health benefits of sulforaphane: a review of the experimental, clinical and epidemiological evidences and underlying mechanisms
-
F. Elbarbry, and N. Elrody Potential health benefits of sulforaphane: a review of the experimental, clinical and epidemiological evidences and underlying mechanisms J. Med. Plant Res. 5 2011 473 484
-
(2011)
J. Med. Plant Res.
, vol.5
, pp. 473-484
-
-
Elbarbry, F.1
Elrody, N.2
-
12
-
-
84898657029
-
Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis
-
M. Galuppo, S. Giacoppo, G.R. De Nicola, R. Iori, M. Navarra, G.E. Lombardo, and et al. Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis Fitoterapia 95 2014 160 174
-
(2014)
Fitoterapia
, vol.95
, pp. 160-174
-
-
Galuppo, M.1
Giacoppo, S.2
De Nicola, G.R.3
Iori, R.4
Navarra, M.5
Lombardo, G.E.6
-
13
-
-
84888634349
-
Pharmacological potentials of Moringa oleifera Lam.: a review
-
S.K. Biswas, A. Chowdhury, J. Das, A. Roy, and S.M. Zahid Hosen Pharmacological potentials of Moringa oleifera Lam.: a review Int. J. Pharm. Sci. Res. 47 2012 305 310
-
(2012)
Int. J. Pharm. Sci. Res.
, vol.47
, pp. 305-310
-
-
Biswas, S.K.1
Chowdhury, A.2
Das, J.3
Roy, A.4
Zahid Hosen, S.M.5
-
14
-
-
69549103145
-
Recent advances in our understanding of neurodegeneration
-
K.A. Jellinger Recent advances in our understanding of neurodegeneration J. Neural Transm. 116 2009 1111 1162
-
(2009)
J. Neural Transm.
, vol.116
, pp. 1111-1162
-
-
Jellinger, K.A.1
-
15
-
-
33947601659
-
Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes
-
V. Calabrese, E. Guagliano, M. Sapienza, M. Panebianco, S. Calafato, E. Puleo, and et al. Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes Neurochem. Res. 32 2007 757 773
-
(2007)
Neurochem. Res.
, vol.32
, pp. 757-773
-
-
Calabrese, V.1
Guagliano, E.2
Sapienza, M.3
Panebianco, M.4
Calafato, S.5
Puleo, E.6
-
17
-
-
84861875282
-
Glucosinolates and isothiocyanates in health and disease
-
A.T. Dinkova-Kostova, and R.V. Kostov Glucosinolates and isothiocyanates in health and disease Trends Mol. Med. 18 2012 337 347
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 337-347
-
-
Dinkova-Kostova, A.T.1
Kostov, R.V.2
-
18
-
-
3042783575
-
A critical review of the bioavailability of glucosinolates and related compounds
-
B. Holst, and G. Williamson A critical review of the bioavailability of glucosinolates and related compounds Nat. Prod. Rep. 21 2004 425 447
-
(2004)
Nat. Prod. Rep.
, vol.21
, pp. 425-447
-
-
Holst, B.1
Williamson, G.2
-
19
-
-
84859102919
-
Natural isothiocyanates: genotoxic potential versus chemoprevention
-
C. Fimognari, E. Turrini, L. Ferruzzi, M. Lenzi, and P. Hrelia Natural isothiocyanates: genotoxic potential versus chemoprevention Mutat. Res. 750 2012 107 131
-
(2012)
Mutat. Res.
, vol.750
, pp. 107-131
-
-
Fimognari, C.1
Turrini, E.2
Ferruzzi, L.3
Lenzi, M.4
Hrelia, P.5
-
20
-
-
84881494802
-
Sulforaphane as a potential protective phytochemical against neurodegenerative diseases
-
A. Tarozzi, C. Angeloni, M. Malaguti, F. Morroni, S. Hrelia, and P. Hrelia Sulforaphane as a potential protective phytochemical against neurodegenerative diseases Oxidative Med. Cell. Longev. 2013 2013 415078
-
(2013)
Oxidative Med. Cell. Longev.
, vol.2013
, pp. 415078
-
-
Tarozzi, A.1
Angeloni, C.2
Malaguti, M.3
Morroni, F.4
Hrelia, S.5
Hrelia, P.6
-
21
-
-
84863979230
-
Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins A, C, and E
-
S. Boddupalli, J.R. Mein, S. Lakkanna, and D.R. James Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins A, C, and E Front. Genet. 3 2012 7
-
(2012)
Front. Genet.
, vol.3
, pp. 7
-
-
Boddupalli, S.1
Mein, J.R.2
Lakkanna, S.3
James, D.R.4
-
22
-
-
3042688047
-
In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat
-
R. Hu, V. Hebbar, B.R. Kim, C. Chen, B. Winnik, B. Buckley, and et al. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat J. Pharmacol. Exp. Ther. 310 2004 263 271
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 263-271
-
-
Hu, R.1
Hebbar, V.2
Kim, B.R.3
Chen, C.4
Winnik, B.5
Buckley, B.6
-
23
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
A.T. Dinkova-Kostova, W.D. Holtzclaw, R.N. Cole, K. Itoh, N. Wakabayashi, Y. Katoh, and et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc. Natl. Acad. Sci. U. S. A. 99 2002 11908 11913
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
-
24
-
-
84961201398
-
Nanoformulated mutant SurR9-C84A: a possible key for Alzheimer's and its associated inflammation
-
B. Sriramoju, R.K. Kanwar, and J.R. Kanwar Nanoformulated mutant SurR9-C84A: a possible key for Alzheimer's and its associated inflammation Pharm. Res. Mar 14 2015 10.1007/s 11095-015-1664-8
-
(2015)
Pharm. Res.
-
-
Sriramoju, B.1
Kanwar, R.K.2
Kanwar, J.R.3
-
25
-
-
0347357617
-
Protein folding and misfolding
-
C.M. Dobson Protein folding and misfolding Nature 426 2003 884 890
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
26
-
-
33846054445
-
The role of tau phosphorylation in the pathogenesis of Alzheimer's disease
-
K. Mi, and G.V. Johnson The role of tau phosphorylation in the pathogenesis of Alzheimer's disease Curr. Alzheimer Res. 3 2006 449 463
-
(2006)
Curr. Alzheimer Res.
, vol.3
, pp. 449-463
-
-
Mi, K.1
Johnson, G.V.2
-
27
-
-
33750016561
-
Selective loss of synaptic proteins in Alzheimer's disease: evidence for an increased severity with APOE ε4
-
R.K. Tannenberg, H.L. Scott, A.E.G. Tannenberg, and P.R. Dodd Selective loss of synaptic proteins in Alzheimer's disease: evidence for an increased severity with APOE ε4 Neurochem. Int. 49 2006 631 639
-
(2006)
Neurochem. Int.
, vol.49
, pp. 631-639
-
-
Tannenberg, R.K.1
Scott, H.L.2
Tannenberg, A.E.G.3
Dodd, P.R.4
-
28
-
-
0032890439
-
Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches
-
C. Behl Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches Prog. Neurobiol. 57 1999 301 323
-
(1999)
Prog. Neurobiol.
, vol.57
, pp. 301-323
-
-
Behl, C.1
-
29
-
-
61349088546
-
Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors
-
A. Salminen, J. Ojala, A. Kauppinen, K. Kaarniranta, and T. Suuronen Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors Prog. Neurobiol. 87 2009 181 194
-
(2009)
Prog. Neurobiol.
, vol.87
, pp. 181-194
-
-
Salminen, A.1
Ojala, J.2
Kauppinen, A.3
Kaarniranta, K.4
Suuronen, T.5
-
30
-
-
33847066706
-
Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy
-
A.L. Goldberg Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy Biochem. Soc. Trans. 35 2007 12 17
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 12-17
-
-
Goldberg, A.L.1
-
31
-
-
59449100511
-
Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome
-
H.-M. Park, J.-A. Kim, and M.-K. Kwak Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome Arch. Pharm. Res. 32 2009 109 115
-
(2009)
Arch. Pharm. Res.
, vol.32
, pp. 109-115
-
-
Park, H.-M.1
Kim, J.-A.2
Kwak, M.-K.3
-
32
-
-
78149260516
-
Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27
-
N. Gan, Y.-C. Wu, M. Brunet, C. Garrido, F.-L. Chung, C. Dai, and et al. Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27 J. Biol. Chem. 285 2010 35528 35536
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35528-35536
-
-
Gan, N.1
Wu, Y.-C.2
Brunet, M.3
Garrido, C.4
Chung, F.-L.5
Dai, C.6
-
33
-
-
0035139109
-
Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases
-
M.Y. Sherman, and A.L. Goldberg Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases Neuron. 29 2001 15 32
-
(2001)
Neuron.
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
34
-
-
84874159254
-
Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model
-
H.V. Kim, H.Y. Kim, H.Y. Ehrlich, S.Y. Choi, D.J. Kim, and Y. Kim Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model Amyloid 20 2013 7 12
-
(2013)
Amyloid
, vol.20
, pp. 7-12
-
-
Kim, H.V.1
Kim, H.Y.2
Ehrlich, H.Y.3
Choi, S.Y.4
Kim, D.J.5
Kim, Y.6
-
35
-
-
84887891608
-
Effects of Brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in PC12 cells and ICR mice
-
J.K. Kim, E.-C. Shin, C.R. Kim, G.G. Park, S.J. Choi, C.-S. Park, and et al. Effects of Brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in PC12 cells and ICR mice J. Med. Food 16 2013 1057 1061
-
(2013)
J. Med. Food
, vol.16
, pp. 1057-1061
-
-
Kim, J.K.1
Shin, E.-C.2
Kim, C.R.3
Park, G.G.4
Choi, S.J.5
Park, C.-S.6
-
36
-
-
61849104057
-
Alteration of brain monoamines & EEG wave pattern in rat model of Alzheimer's disease & protection by Moringa oleifera
-
R. Ganguly, and D. Guha Alteration of brain monoamines & EEG wave pattern in rat model of Alzheimer's disease & protection by Moringa oleifera Indian J. Med. Res. 128 2008 744 751
-
(2008)
Indian J. Med. Res.
, vol.128
, pp. 744-751
-
-
Ganguly, R.1
Guha, D.2
-
37
-
-
61849140503
-
Effect of Moringa oleifera in experimental model of Alzheimer's disease: role of antioxidants
-
R. Ganguly, K. Ray, and D. Guha Effect of Moringa oleifera in experimental model of Alzheimer's disease: role of antioxidants Ann. Neurosci. 12 2005 36 39
-
(2005)
Ann. Neurosci.
, vol.12
, pp. 36-39
-
-
Ganguly, R.1
Ray, K.2
Guha, D.3
-
38
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
T.M. Dawson, and V.L. Dawson Molecular pathways of neurodegeneration in Parkinson's disease Science 302 5646 2003 819 822
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
40
-
-
79957515007
-
Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism
-
A. Jazwa, A.I. Rojo, N.G. Innamorato, M. Hesse, J. Fernandez-Ruiz, and A. Cuadrado Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism Antioxid. Redox Signal. 14 2011 2347 2360
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2347-2360
-
-
Jazwa, A.1
Rojo, A.I.2
Innamorato, N.G.3
Hesse, M.4
Fernandez-Ruiz, J.5
Cuadrado, A.6
-
41
-
-
84876376158
-
Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease
-
F. Morroni, A. Tarozzi, G. Sita, C. Bolondi, J.M. Zolezzi Moraga, G. Cantelli-Forti, and P. Hrelia Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease Neurotoxicology 36 2013 63 71
-
(2013)
Neurotoxicology
, vol.36
, pp. 63-71
-
-
Morroni, F.1
Tarozzi, A.2
Sita, G.3
Bolondi, C.4
Zolezzi Moraga, J.M.5
Cantelli-Forti, G.6
Hrelia, P.7
-
42
-
-
84858207203
-
4-Iodophenyl isothiocyanate: a neuroprotective compound
-
A. Wellejus, H. Elbrond-Bek, N.M. Kelly, M.S. Weidner, and S.H. Jorgensen 4-Iodophenyl isothiocyanate: a neuroprotective compound Restor. Neurol. Neurosci. 30 2012 21 38
-
(2012)
Restor. Neurol. Neurosci.
, vol.30
, pp. 21-38
-
-
Wellejus, A.1
Elbrond-Bek, H.2
Kelly, N.M.3
Weidner, M.S.4
Jorgensen, S.H.5
-
44
-
-
70350761712
-
Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line
-
A. Tarozzi, F. Morroni, A. Merlicco, S. Hrelia, C. Angeloni, G. Cantelli-Forti, and et al. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line J. Neurochem. 111 2009 1161 1171
-
(2009)
J. Neurochem.
, vol.111
, pp. 1161-1171
-
-
Tarozzi, A.1
Morroni, F.2
Merlicco, A.3
Hrelia, S.4
Angeloni, C.5
Cantelli-Forti, G.6
-
45
-
-
84861651453
-
Inhibition of 6-hydroxydopamine-induced endoplasmic reticulum stress by sulforaphane through the activation of Nrf2 nuclear translocation
-
C. Deng, R. Tao, S.Z. Yu, and H. Jin Inhibition of 6-hydroxydopamine-induced endoplasmic reticulum stress by sulforaphane through the activation of Nrf2 nuclear translocation Mol. Med. Rep. 6 2012 215 219
-
(2012)
Mol. Med. Rep.
, vol.6
, pp. 215-219
-
-
Deng, C.1
Tao, R.2
Yu, S.Z.3
Jin, H.4
-
46
-
-
84856257180
-
Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner
-
C. Deng, R. Tao, S.Z. Yu, and H. Jin Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner Mol. Med. Rep. 5 2012 847 851
-
(2012)
Mol. Med. Rep.
, vol.5
, pp. 847-851
-
-
Deng, C.1
Tao, R.2
Yu, S.Z.3
Jin, H.4
-
47
-
-
33947379500
-
Protective effect of sulforaphane against dopaminergic cell death
-
J.M. Han, Y.J. Lee, S.Y. Lee, E.M. Kim, Y. Moon, H.W. Kim, and et al. Protective effect of sulforaphane against dopaminergic cell death J. Pharmacol. Exp. Ther. 321 2007 249 256
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 249-256
-
-
Han, J.M.1
Lee, Y.J.2
Lee, S.Y.3
Kim, E.M.4
Moon, Y.5
Kim, H.W.6
-
48
-
-
0036074531
-
5-S-cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons
-
J.P.E. Spencer, M. Whiteman, P. Jenner, and B. Halliwell 5-S-cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons J. Neurochem. 81 2002 122 129
-
(2002)
J. Neurochem.
, vol.81
, pp. 122-129
-
-
Spencer, J.P.E.1
Whiteman, M.2
Jenner, P.3
Halliwell, B.4
-
49
-
-
34548250927
-
Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols
-
D. Vauzour, K. Vafeiadou, and J.P.E. Spencer Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols Biochem. Biophys. Res. Commun. 362 2007 340 346
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.362
, pp. 340-346
-
-
Vauzour, D.1
Vafeiadou, K.2
Spencer, J.P.E.3
-
50
-
-
0031722906
-
Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species
-
J.P.E. Spencer, P. Jenner, S.E. Daniel, A.J. Lees, D.C. Marsden, and B. Halliwell Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species J. Neurochem. 71 1998 2112 2122
-
(1998)
J. Neurochem.
, vol.71
, pp. 2112-2122
-
-
Spencer, J.P.E.1
Jenner, P.2
Daniel, S.E.3
Lees, A.J.4
Marsden, D.C.5
Halliwell, B.6
-
51
-
-
77951076084
-
Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes
-
D. Vauzour, M. Buonfiglio, G. Corona, J. Chirafisi, K. Vafeiadou, C. Angeloni, and et al. Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes Mol. Nutr. Food Res. 54 2010 532 542
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 532-542
-
-
Vauzour, D.1
Buonfiglio, M.2
Corona, G.3
Chirafisi, J.4
Vafeiadou, K.5
Angeloni, C.6
-
52
-
-
78650031174
-
Huntington's disease: from molecular pathogenesis to clinical treatment
-
C.A. Ross, and S.J. Tabrizi Huntington's disease: from molecular pathogenesis to clinical treatment Lancet Neurol. 10 2011 83 98
-
(2011)
Lancet Neurol.
, vol.10
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
53
-
-
34547092719
-
Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma cells
-
M.-K. Kwak, J.-M. Cho, B. Huang, S. Shin, and T.W. Kensler Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma cells Free Radic. Biol. Med. 43 2007 809 817
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 809-817
-
-
Kwak, M.-K.1
Cho, J.-M.2
Huang, B.3
Shin, S.4
Kensler, T.W.5
-
54
-
-
84899421127
-
Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease
-
Y. Liu, C.L. Hettinger, D. Zhang, K. Rezvani, X. Wang, and H. Wang Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease J. Neurochem. 129 2014 539 547
-
(2014)
J. Neurochem.
, vol.129
, pp. 539-547
-
-
Liu, Y.1
Hettinger, C.L.2
Zhang, D.3
Rezvani, K.4
Wang, X.5
Wang, H.6
-
55
-
-
17644396349
-
Immunology of multiple sclerosis
-
M. Sospedra, and R. Martin Immunology of multiple sclerosis Annu. Rev. Immunol. 23 2005 683 747
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
56
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
R. Gold, C. Linington, and H. Lassmann Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research Brain 129 2006 1953 1971
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
57
-
-
84886237017
-
Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice
-
B. Li, W. Cui, J. Liu, R. Li, Q. Liu, X.-H. Xie, and et al. Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice Exp. Neurol. 250 2013 239 249
-
(2013)
Exp. Neurol.
, vol.250
, pp. 239-249
-
-
Li, B.1
Cui, W.2
Liu, J.3
Li, R.4
Liu, Q.5
Xie, X.-H.6
-
58
-
-
78649467294
-
Nutraceutical antioxidants as novel neuroprotective agents
-
N.A. Kelsey, H.M. Wilkins, and D.A. Linseman Nutraceutical antioxidants as novel neuroprotective agents Molecules. 15 2010 7792 7814
-
(2010)
Molecules.
, vol.15
, pp. 7792-7814
-
-
Kelsey, N.A.1
Wilkins, H.M.2
Linseman, D.A.3
-
62
-
-
77955423158
-
Mutant, and TAR, DNA-binding protein-43 induces oxidative injury in motor neuron-like cell
-
W. Duan, X. Li, J. Shi, Y. Guo, Z. Li, Li C. Mutant, and TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell Neuroscience 169 2010 1621 1629
-
(2010)
Neuroscience
, vol.169
, pp. 1621-1629
-
-
Duan, W.1
Li, X.2
Shi, J.3
Guo, Y.4
Li, Z.5
Li, C.6
-
63
-
-
70350125985
-
Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats
-
M. Malaguti, C. Angeloni, N. Garatachea, M. Baldini, E. Leoncini, P.S. Collado, and et al. Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats J. Appl. Physiol. 107 2009 1028 1036
-
(2009)
J. Appl. Physiol.
, vol.107
, pp. 1028-1036
-
-
Malaguti, M.1
Angeloni, C.2
Garatachea, N.3
Baldini, M.4
Leoncini, E.5
Collado, P.S.6
-
64
-
-
77957550194
-
Protective effect of combination of sulforaphane and riluzole on glutamate-mediated excitotoxicity
-
G. Chang, Y. Guo, Y. Jia, W. Duan, B. Li, J. Yu, and et al. Protective effect of combination of sulforaphane and riluzole on glutamate-mediated excitotoxicity Biol. Pharm. Bull. 33 2010 1477 1483
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 1477-1483
-
-
Chang, G.1
Guo, Y.2
Jia, Y.3
Duan, W.4
Li, B.5
Yu, J.6
-
65
-
-
84929643640
-
Administration of 4-(α-l-rhamnosyloxy)-benzyl isothiocyanate delays disease phenotype in SOD1G93A rats: a transgenic model of amyotrophic lateral sclerosis
-
M. Galuppo, S. Giacoppo, R. Iori, G.R. De Nicola, P. Bramanti, and E. Mazzon Administration of 4-(α-l-rhamnosyloxy)-benzyl isothiocyanate delays disease phenotype in SOD1G93A rats: a transgenic model of amyotrophic lateral sclerosis BioMed. Res. Int. 2015 10.1155/2015/259417
-
(2015)
BioMed. Res. Int.
-
-
Galuppo, M.1
Giacoppo, S.2
Iori, R.3
De Nicola, G.R.4
Bramanti, P.5
Mazzon, E.6
-
66
-
-
0043013350
-
Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century
-
V.L. Feigin, C.M.M. Lawes, D.A. Bennett, and C.S. Anderson Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century Lancet Neurol. 2 2003 43 53
-
(2003)
Lancet Neurol.
, vol.2
, pp. 43-53
-
-
Feigin, V.L.1
Lawes, C.M.M.2
Bennett, D.A.3
Anderson, C.S.4
-
67
-
-
84893651437
-
Heart disease and stroke statistics - 2014 update: a report from the American Heart Association
-
A.S. Go, D. Mozaffarian, V.L. Roger, E.J. Benjamin, J.D. Berry, M.J. Blaha, and et al. Heart disease and stroke statistics - 2014 update: a report from the American Heart Association Circulation 129 2014 e28 e292
-
(2014)
Circulation
, vol.129
, pp. e28-e292
-
-
Go, A.S.1
Mozaffarian, D.2
Roger, V.L.3
Benjamin, E.J.4
Berry, J.D.5
Blaha, M.J.6
-
68
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
P.H. Chan Reactive oxygen radicals in signaling and damage in the ischemic brain J. Cereb. Blood Flow Metab. 21 2001 2 14
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
69
-
-
77952513645
-
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
-
R. Jin, G. Yang, and G. Li Inflammatory mechanisms in ischemic stroke: role of inflammatory cells J. Leukoc. Biol. 87 2010 779 789
-
(2010)
J. Leukoc. Biol.
, vol.87
, pp. 779-789
-
-
Jin, R.1
Yang, G.2
Li, G.3
-
70
-
-
0033979993
-
Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia
-
G. del Zoppo, I. Ginis, J.M. Hallenbeck, C. Iadecola, X. Wang, and G.Z. Feuerstein Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia Brain Pathol. 10 2000 95 112
-
(2000)
Brain Pathol.
, vol.10
, pp. 95-112
-
-
Del Zoppo, G.1
Ginis, I.2
Hallenbeck, J.M.3
Iadecola, C.4
Wang, X.5
Feuerstein, G.Z.6
-
71
-
-
77955487488
-
The science of stroke: mechanisms in search of treatments
-
M.A. Moskowitz, E.H. Lo, and C. Iadecola The science of stroke: mechanisms in search of treatments Neuron 67 2010 181 198
-
(2010)
Neuron
, vol.67
, pp. 181-198
-
-
Moskowitz, M.A.1
Lo, E.H.2
Iadecola, C.3
-
72
-
-
84908030091
-
S)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats
-
S)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats Fitoterapia 99 2014 166 177
-
(2014)
Fitoterapia
, vol.99
, pp. 166-177
-
-
Giacoppo, S.1
Galuppo, M.2
Iori, R.3
De Nicola, G.R.4
Bramanti, P.5
Mazzon, E.6
-
74
-
-
29244479186
-
Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
-
J. Zhao, N. Kobori, J. Aronowski, and P.K. Dash Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents Neurosci. Lett. 393 2006 108 112
-
(2006)
Neurosci. Lett.
, vol.393
, pp. 108-112
-
-
Zhao, J.1
Kobori, N.2
Aronowski, J.3
Dash, P.K.4
-
75
-
-
49749117926
-
Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death
-
A.I. Rojo, P. Rada, J. Egea, A.O. Rosa, M.G. Lopez, and A. Cuadrado Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death Mol. Cell. Neurosci. 39 2008 125 132
-
(2008)
Mol. Cell. Neurosci.
, vol.39
, pp. 125-132
-
-
Rojo, A.I.1
Rada, P.2
Egea, J.3
Rosa, A.O.4
Lopez, M.G.5
Cuadrado, A.6
-
76
-
-
77953620909
-
Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme
-
Z. Ping, W. Liu, Z. Kang, J. Cai, Q. Wang, N. Cheng, and et al. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme Brain Res. 1343 2010 178 185
-
(2010)
Brain Res.
, vol.1343
, pp. 178-185
-
-
Ping, Z.1
Liu, W.2
Kang, Z.3
Cai, J.4
Wang, Q.5
Cheng, N.6
-
77
-
-
77951526269
-
Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation
-
L. Soane, W. Li Dai, G. Fiskum, and L.L. Bambrick Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation J. Neurosci. Res. 88 2010 1355 1363
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 1355-1363
-
-
Soane, L.1
Li Dai, W.2
Fiskum, G.3
Bambrick, L.L.4
-
78
-
-
65549118899
-
Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation
-
C.A. Danilov, K. Chandrasekaran, J. Racz, L. Soane, C. Zielke, and G. Fiskum Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation Glia 57 2009 645 656
-
(2009)
Glia
, vol.57
, pp. 645-656
-
-
Danilov, C.A.1
Chandrasekaran, K.2
Racz, J.3
Soane, L.4
Zielke, C.5
Fiskum, G.6
-
79
-
-
84988372343
-
4-(α-l-Rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that defends cerebral tissue and prevents severe damage induced by focal ischemia/reperfusion
-
M. Galuppo, S. Giacoppo, R. Iori, G.R. De Nicola, D. Milardi, P. Bramanti, and et al. 4-(α-l-Rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that defends cerebral tissue and prevents severe damage induced by focal ischemia/reperfusion J. Biol. Regul. Homeost. Agents 29 2015 343 356
-
(2015)
J. Biol. Regul. Homeost. Agents
, vol.29
, pp. 343-356
-
-
Galuppo, M.1
Giacoppo, S.2
Iori, R.3
De Nicola, G.R.4
Milardi, D.5
Bramanti, P.6
-
80
-
-
84893857613
-
Cerebroprotective effect of Moringa oleifera against focal ischemic stroke induced by middle cerebral artery occlusion
-
W. Kirisattayakul, J. Wattanathorn, T. Tong-Un, S. Muchimapura, P. Wannanon, and J. Jittiwat Cerebroprotective effect of Moringa oleifera against focal ischemic stroke induced by middle cerebral artery occlusion Oxidative Med. Cell. Longev. 2013 2013 951415
-
(2013)
Oxidative Med. Cell. Longev.
, vol.2013
, pp. 951415
-
-
Kirisattayakul, W.1
Wattanathorn, J.2
Tong-Un, T.3
Muchimapura, S.4
Wannanon, P.5
Jittiwat, J.6
-
81
-
-
46849094295
-
Moderate and severe traumatic brain injury in adults
-
A.I.R. Maas, N. Stocchetti, and R. Bullock Moderate and severe traumatic brain injury in adults Lancet Neurol. 7 2008 728 741
-
(2008)
Lancet Neurol.
, vol.7
, pp. 728-741
-
-
Maas, A.I.R.1
Stocchetti, N.2
Bullock, R.3
-
82
-
-
0347990376
-
The neurophysiology of brain injury
-
M. Gaetz The neurophysiology of brain injury Clin. Neurophysiol. 115 2004 4 18
-
(2004)
Clin. Neurophysiol.
, vol.115
, pp. 4-18
-
-
Gaetz, M.1
-
83
-
-
66949123850
-
Sulforaphane improves cognitive function administered following traumatic brain injury
-
P.K. Dash, J. Zhao, S.A. Orsi, M. Zhang, and A.N. Moore Sulforaphane improves cognitive function administered following traumatic brain injury Neurosci. Lett. 460 2009 103 107
-
(2009)
Neurosci. Lett.
, vol.460
, pp. 103-107
-
-
Dash, P.K.1
Zhao, J.2
Orsi, S.A.3
Zhang, M.4
Moore, A.N.5
-
84
-
-
27644587832
-
Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury
-
J. Zhao, A.N. Moore, G.L. Clifton, and P.K. Dash Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury J. Neurosci. Res. 82 2005 499 506
-
(2005)
J. Neurosci. Res.
, vol.82
, pp. 499-506
-
-
Zhao, J.1
Moore, A.N.2
Clifton, G.L.3
Dash, P.K.4
-
85
-
-
34548850603
-
Enhancing expression of Nrf2-driven genes protects the blood-brain barrier after brain injury
-
J. Zhao, A.N. Moore, J.B. Redell, and P.K. Dash Enhancing expression of Nrf2-driven genes protects the blood-brain barrier after brain injury J. Neurosci. 27 2007 10240 10248
-
(2007)
J. Neurosci.
, vol.27
, pp. 10240-10248
-
-
Zhao, J.1
Moore, A.N.2
Redell, J.B.3
Dash, P.K.4
-
86
-
-
1842419475
-
Degenerative and regenerative mechanisms governing spinal cord injury
-
C. Profyris, S.S. Cheema, D. Zang, M.F. Azari, K. Boyle, and S. Petratos Degenerative and regenerative mechanisms governing spinal cord injury Neurobiol. Dis. 15 2004 415 436
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 415-436
-
-
Profyris, C.1
Cheema, S.S.2
Zang, D.3
Azari, M.F.4
Boyle, K.5
Petratos, S.6
-
87
-
-
80051549591
-
Transcription factor Nrf2 protects the spinal cord from inflammation produced by spinal cord injury
-
L. Mao, H. Wang, X. Wang, H. Liao, and X. Zhao Transcription factor Nrf2 protects the spinal cord from inflammation produced by spinal cord injury J. Surg. Res. 170 2011 e105 e115
-
(2011)
J. Surg. Res.
, vol.170
, pp. e105-e115
-
-
Mao, L.1
Wang, H.2
Wang, X.3
Liao, H.4
Zhao, X.5
-
88
-
-
84869065449
-
Neuroprotective effects of sulforaphane after contusive spinal cord injury
-
A.L. Benedict, A. Mountney, A. Hurtado, K.E. Bryan, R.L. Schnaar, A.T. Dinkova-Kostova, and et al. Neuroprotective effects of sulforaphane after contusive spinal cord injury J. Neurotrauma 29 2012 2576 2586
-
(2012)
J. Neurotrauma
, vol.29
, pp. 2576-2586
-
-
Benedict, A.L.1
Mountney, A.2
Hurtado, A.3
Bryan, K.E.4
Schnaar, R.L.5
Dinkova-Kostova, A.T.6
-
89
-
-
77958071059
-
Sulforaphane attenuates matrix metalloproteinase-9 expression following spinal cord injury in mice
-
L. Mao, H.D. Wang, X.L. Wang, L. Qiao, and H.X. Yin Sulforaphane attenuates matrix metalloproteinase-9 expression following spinal cord injury in mice Ann. Clin. Lab. Sci. 40 2010 354 360
-
(2010)
Ann. Clin. Lab. Sci.
, vol.40
, pp. 354-360
-
-
Mao, L.1
Wang, H.D.2
Wang, X.L.3
Qiao, L.4
Yin, H.X.5
-
90
-
-
84863338153
-
Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury
-
X. Wang, J.P. de Rivero Vaccari, H. Wang, P. Diaz, R. German, A.E. Marcillo, and et al. Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury J. Neurotrauma 29 2012 936 945
-
(2012)
J. Neurotrauma
, vol.29
, pp. 936-945
-
-
Wang, X.1
De Rivero Vaccari, J.P.2
Wang, H.3
Diaz, P.4
German, R.5
Marcillo, A.E.6
-
91
-
-
84887465716
-
S)-glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model
-
S)-glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model J. Neurol. Sci. 334 2013 88 96
-
(2013)
J. Neurol. Sci.
, vol.334
, pp. 88-96
-
-
Galuppo, M.1
Giacoppo, S.2
De Nicola, G.R.3
Iori, R.4
Mazzon, E.5
Bramanti, P.6
-
92
-
-
84918809163
-
4-(α-l-Rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that attenuates secondary damage in an experimental model of spinal cord injury
-
S. Giacoppo, M. Galuppo, G.R. De Nicola, R. Iori, P. Bramanti, and E. Mazzon 4-(α-l-Rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that attenuates secondary damage in an experimental model of spinal cord injury Bioorg. Med. Chem. 23 2015 80 88
-
(2015)
Bioorg. Med. Chem.
, vol.23
, pp. 80-88
-
-
Giacoppo, S.1
Galuppo, M.2
De Nicola, G.R.3
Iori, R.4
Bramanti, P.5
Mazzon, E.6
|